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Items: 1 to 50 of 111

1.

Enabling the Advanced Bioeconomy through Public Policy Supporting Biofoundries and Engineering Biology.

Kitney R, Adeogun M, Fujishima Y, Goñi-Moreno Á, Johnson R, Maxon M, Steedman S, Ward S, Winickoff D, Philp J.

Trends Biotechnol. 2019 Sep;37(9):917-920. doi: 10.1016/j.tibtech.2019.03.017. Epub 2019 Apr 26.

PMID:
31036350
2.

4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors.

Philp J, Lawhorn BG, Graves AP, Shewchuk L, Rivera KL, Jolivette LJ, Holt DA, Gatto GJ Jr, Kallander LS.

J Med Chem. 2018 Apr 12;61(7):3076-3088. doi: 10.1021/acs.jmedchem.8b00125. Epub 2018 Mar 21.

PMID:
29561151
3.

Clusters in Industrial Biotechnology and Bioeconomy: The Roles of the Public Sector.

Philp J, Winickoff DE.

Trends Biotechnol. 2017 Aug;35(8):682-686. doi: 10.1016/j.tibtech.2017.04.004. Epub 2017 May 6.

PMID:
28487123
4.

The bioeconomy, the challenge of the century for policy makers.

Philp J.

N Biotechnol. 2018 Jan 25;40(Pt A):11-19. doi: 10.1016/j.nbt.2017.04.004. Epub 2017 May 6. Review.

PMID:
28487094
5.

Development and feasibility of a Swallowing intervention Package (SiP) for patients receiving radiotherapy treatment for head and neck cancer-the SiP study protocol.

Wells M, King E, Toft K, MacAulay F, Patterson J, Dougall N, Hulbert-Williams N, Boa S, Slaven E, Cowie J, McGarva J, Niblock PG, Philp J, Roe J.

Pilot Feasibility Stud. 2016 Aug 4;2:40. eCollection 2016.

6.

Substituent Effects on Drug-Receptor H-bond Interactions: Correlations Useful for the Design of Kinase Inhibitors.

Lawhorn BG, Philp J, Graves AP, Holt DA, Gatto GJ Jr, Kallander LS.

J Med Chem. 2016 Dec 8;59(23):10629-10641. Epub 2016 Nov 22.

PMID:
27933961
7.

Policy: Five cornerstones of a global bioeconomy.

El-Chichakli B, von Braun J, Lang C, Barben D, Philp J.

Nature. 2016 Jul 14;535(7611):221-3. doi: 10.1038/535221a. No abstract available.

PMID:
27411618
8.

GSK114: A selective inhibitor for elucidating the biological role of TNNI3K.

Lawhorn BG, Philp J, Graves AP, Shewchuk L, Holt DA, Gatto GJ Jr, Kallander LS.

Bioorg Med Chem Lett. 2016 Jul 15;26(14):3355-3358. doi: 10.1016/j.bmcl.2016.05.033. Epub 2016 May 14.

PMID:
27246618
9.

Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey.

Wells M, Swartzman S, Lang H, Cunningham M, Taylor L, Thomson J, Philp J, McCowan C.

Support Care Cancer. 2016 Jun;24(6):2463-72. doi: 10.1007/s00520-015-3045-6. Epub 2015 Dec 11.

PMID:
26660345
10.

Agricultural vulnerability over the Chinese Loess Plateau in response to climate change: Exposure, sensitivity, and adaptive capacity.

Li X, Philp J, Cremades R, Roberts A, He L, Li L, Yu Q.

Ambio. 2016 Apr;45(3):350-60. doi: 10.1007/s13280-015-0727-8. Epub 2015 Nov 12.

11.

Recurrent Painful Abdominal Rash.

Ridgeway-Diaz JG, Philp JC, North JP.

JAMA. 2015 Oct 6;314(13):1390-1. doi: 10.1001/jama.2015.9308. No abstract available.

PMID:
26441185
12.

Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K).

Lawhorn BG, Philp J, Zhao Y, Louer C, Hammond M, Cheung M, Fries H, Graves AP, Shewchuk L, Wang L, Cottom JE, Qi H, Zhao H, Totoritis R, Zhang G, Schwartz B, Li H, Sweitzer S, Holt DA, Gatto GJ Jr, Kallander LS.

J Med Chem. 2015 Sep 24;58(18):7431-48. doi: 10.1021/acs.jmedchem.5b00931. Epub 2015 Sep 10.

PMID:
26355916
13.

Distress, concerns and unmet needs in survivors of head and neck cancer: a cross-sectional survey.

Wells M, Cunningham M, Lang H, Swartzman S, Philp J, Taylor L, Thomson J.

Eur J Cancer Care (Engl). 2015 Sep;24(5):748-60. doi: 10.1111/ecc.12370. Epub 2015 Aug 7.

PMID:
26250705
14.

Policy: Define biomass sustainability.

Bosch R, van de Pol M, Philp J.

Nature. 2015 Jul 30;523(7562):526-7. doi: 10.1038/523526a. No abstract available.

PMID:
26223612
15.

Oil spill problems and sustainable response strategies through new technologies.

Ivshina IB, Kuyukina MS, Krivoruchko AV, Elkin AA, Makarov SO, Cunningham CJ, Peshkur TA, Atlas RM, Philp JC.

Environ Sci Process Impacts. 2015 Jul;17(7):1201-19. doi: 10.1039/c5em00070j.

16.

Omics and the bioeconomy: Applications of genomics hold great potential for a future bio-based economy and sustainable development.

Jiménez-Sánchez G, Philp J.

EMBO Rep. 2015 Jan;16(1):17-20. doi: 10.15252/embr.201439409. Epub 2014 Dec 4. No abstract available.

17.

Biorefining policy needs to come of age.

Schieb PA, Philp JC.

Trends Biotechnol. 2014 Oct;32(10):496-500. doi: 10.1016/j.tibtech.2014.08.006. Review.

PMID:
25246169
18.

Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.

Vagnozzi RJ, Gatto GJ Jr, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T.

Sci Transl Med. 2013 Oct 16;5(207):207ra141. doi: 10.1126/scitranslmed.3006479.

19.

Pediatric teledermatology consultations: relationship between provided data and diagnosis.

Philp JC, Frieden IJ, Cordoro KM.

Pediatr Dermatol. 2013 Sep-Oct;30(5):561-7. doi: 10.1111/pde.12180. Epub 2013 Jul 26.

PMID:
23889079
20.

Bioremediation, an environmental remediation technology for the bioeconomy.

Gillespie IM, Philp JC.

Trends Biotechnol. 2013 Jun;31(6):329-32. doi: 10.1016/j.tibtech.2013.01.015. Epub 2013 Feb 18.

PMID:
23427900
21.

Biomass sustainability and certification.

Pavanan KC, Bosch RA, Cornelissen R, Philp JC.

Trends Biotechnol. 2013 Jul;31(7):385-7. doi: 10.1016/j.tibtech.2013.01.014. Epub 2013 Feb 19.

PMID:
23427899
22.

Biobased chemicals: the convergence of green chemistry with industrial biotechnology.

Philp JC, Ritchie RJ, Allan JE.

Trends Biotechnol. 2013 Apr;31(4):219-22. doi: 10.1016/j.tibtech.2012.12.007. Epub 2013 Feb 8.

23.

Policy to support marine biotechnology-based solutions to global challenges.

Ritchie RJ, Guy K, Philp JC.

Trends Biotechnol. 2013 Mar;31(3):128-31. doi: 10.1016/j.tibtech.2013.01.009. Epub 2013 Feb 8.

PMID:
23394961
24.

Synthetic biology, the bioeconomy, and a societal quandary.

Philp JC, Ritchie RJ, Allan JE.

Trends Biotechnol. 2013 May;31(5):269-72. doi: 10.1016/j.tibtech.2013.01.011. Epub 2013 Feb 8.

PMID:
23394960
25.

Biobased plastics in a bioeconomy.

Philp JC, Ritchie RJ, Guy K.

Trends Biotechnol. 2013 Feb;31(2):65-7. doi: 10.1016/j.tibtech.2012.11.009. Epub 2013 Jan 17.

PMID:
23333433
26.

Bioplastics science from a policy vantage point.

Philp JC, Bartsev A, Ritchie RJ, Baucher MA, Guy K.

N Biotechnol. 2013 Sep 25;30(6):635-46. doi: 10.1016/j.nbt.2012.11.021. Epub 2012 Dec 5. Review.

PMID:
23220474
27.

Biofuels development and the policy regime.

Philp JC, Guy K, Ritchie RJ.

Trends Biotechnol. 2013 Jan;31(1):4-6. doi: 10.1016/j.tibtech.2012.10.001. Epub 2012 Nov 20.

PMID:
23174283
28.

In vivo activity of an azole series of CCR2 antagonists.

Smethurst CA, Bevan N, Brooks C, Emmons A, Gough PJ, Mookherjee C, Moores K, Peace S, Philp J, Piercy V, Watson SP, Zippoli M.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7252-5. doi: 10.1016/j.bmcl.2012.09.020. Epub 2012 Sep 23. Erratum in: Bioorg Med Chem Lett. 2013 Jan 1;23(1):382.

PMID:
23079519
29.

Complementary and alternative medicine use and adherence with pediatric asthma treatment.

Philp JC, Maselli J, Pachter LM, Cabana MD.

Pediatrics. 2012 May;129(5):e1148-54. doi: 10.1542/peds.2011-2467. Epub 2012 Apr 9.

30.

Potential barriers to veterinary student access to counselling and other support systems: perceptions of staff and students at a UK veterinary school.

Pickles KJ, Rhind SM, Miller R, Jackson S, Allister R, Philp J, Waterhouse L, Mellanby RJ.

Vet Rec. 2012 Feb 4;170(5):124. doi: 10.1136/vr.100179. Epub 2011 Dec 20.

PMID:
22186377
31.

Allergic Drug Reactions.

Philp JR.

In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 214.

32.

Identification of a sulfonamide series of CCR2 antagonists.

Peace S, Philp J, Brooks C, Piercy V, Moores K, Smethurst C, Watson S, Gaines S, Zippoli M, Mookherjee C, Ife R.

Bioorg Med Chem Lett. 2010 Jul 1;20(13):3961-4. doi: 10.1016/j.bmcl.2010.04.142. Epub 2010 May 7.

PMID:
20627722
33.

Field scale molecular analysis for the monitoring of bacterial community structures during on-site diesel bioremediation.

Ciric L, Griffiths RI, Philp JC, Whiteley AS.

Bioresour Technol. 2010 Jul;101(14):5235-41. doi: 10.1016/j.biortech.2010.02.065. Epub 2010 Mar 19.

PMID:
20303748
34.

Hydrocarbon utilization within a diesel-degrading bacterial consortium.

Ciric L, Philp JC, Whiteley AS.

FEMS Microbiol Lett. 2010 Feb;303(2):116-22. doi: 10.1111/j.1574-6968.2009.01871.x. Epub 2009 Dec 3.

35.

Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).

Wagner CE, Jurutka PW, Marshall PA, Groy TL, van der Vaart A, Ziller JW, Furmick JK, Graeber ME, Matro E, Miguel BV, Tran IT, Kwon J, Tedeschi JN, Moosavi S, Danishyar A, Philp JS, Khamees RO, Jackson JN, Grupe DK, Badshah SL, Hart JW.

J Med Chem. 2009 Oct 8;52(19):5950-66. doi: 10.1021/jm900496b.

36.

Barriers to palliative care for children: perceptions of pediatric health care providers.

Davies B, Sehring SA, Partridge JC, Cooper BA, Hughes A, Philp JC, Amidi-Nouri A, Kramer RF.

Pediatrics. 2008 Feb;121(2):282-8. doi: 10.1542/peds.2006-3153.

PMID:
18245419
37.

The discovery of GSK221149A: a potent and selective oxytocin antagonist.

Liddle J, Allen MJ, Borthwick AD, Brooks DP, Davies DE, Edwards RM, Exall AM, Hamlett C, Irving WR, Mason AM, McCafferty GP, Nerozzi F, Peace S, Philp J, Pollard D, Pullen MA, Shabbir SS, Sollis SL, Westfall TD, Woollard PM, Wu C, Hickey DM.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):90-4. Epub 2007 Nov 6.

PMID:
18032036
38.

Hydrophobised sawdust as a carrier for immobilisation of the hydrocarbon-oxidizing bacterium Rhodococcus ruber.

Podorozhko EA, Lozinsky VI, Ivshina IB, Kuyukina MS, Krivorutchko AB, Philp JC, Cunningham CJ.

Bioresour Technol. 2008 Apr;99(6):2001-8. Epub 2007 May 3.

PMID:
17481891
39.

Academic medicine. Who should call the tune?

Philp JR.

BMJ. 2007 Mar 10;334(7592):491. No abstract available.

40.

Phase-variable surface structures are required for infection of Campylobacter jejuni by bacteriophages.

Coward C, Grant AJ, Swift C, Philp J, Towler R, Heydarian M, Frost JA, Maskell DJ.

Appl Environ Microbiol. 2006 Jul;72(7):4638-47.

41.

Immobilization of hydrocarbon-oxidizing bacteria in poly(vinyl alcohol) cryogels hydrophobized using a biosurfactant.

Kuyukina MS, Ivshina IB, Gavrin AY, Podorozhko EA, Lozinsky VI, Jeffree CE, Philp JC.

J Microbiol Methods. 2006 Jun;65(3):596-603. Epub 2005 Nov 28.

PMID:
16316701
42.

Effect of biosurfactants on crude oil desorption and mobilization in a soil system.

Kuyukina MS, Ivshina IB, Makarov SO, Litvinenko LV, Cunningham CJ, Philp JC.

Environ Int. 2005 Feb;31(2):155-61.

PMID:
15661276
43.

Calibration and deployment of custom-designed bioreporters for protecting biological remediation consortia from toxic shock.

Wiles S, Lilley AK, Philp JC, Bailey MJ, Whiteley AS.

Environ Microbiol. 2005 Feb;7(2):260-9.

PMID:
15658993
44.

Methods evaluating vanadium tolerance in bacteria isolated from crude oil contaminated land.

Bell JM, Philp JC, Kuyukina MS, Ivshina IB, Dunbar SA, Cunningham CJ, Anderson P.

J Microbiol Methods. 2004 Jul;58(1):87-100.

PMID:
15177907
45.

Field trial of a new aeration system for enhancing biodegradation in a biopile.

Li L, Cunningham CJ, Pas V, Philp JC, Barry DA, Anderson P.

Waste Manag. 2004;24(2):127-37.

PMID:
14761751
46.
47.

Alkanotrophic Rhodococcus ruber as a biosurfactant producer.

Philp JC, Kuyukina MS, Ivshina IB, Dunbar SA, Christofi N, Lang S, Wray V.

Appl Microbiol Biotechnol. 2002 Jul;59(2-3):318-24. Epub 2002 May 9.

PMID:
12111164
48.

Recovery of Rhodococcus biosurfactants using methyl tertiary-butyl ether extraction.

Kuyukina MS, Ivshina IB, Philp JC, Christofi N, Dunbar SA, Ritchkova MI.

J Microbiol Methods. 2001 Aug;46(2):149-56.

PMID:
11412925
49.

Ecological and physiological analyses of Pseudomonad species within a phenol remediation system.

Whiteley AS, Wiles S, Lilley AK, Philp J, Bailey MJ.

J Microbiol Methods. 2001 Feb 1;44(1):79-88.

PMID:
11166102
50.

Identification and environmental detection of Rhodococcus species by 16S rDNA-targeted PCR.

Bell KS, Kuyukina MS, Heidbrink S, Philp JC, Aw DW, Ivshina IB, Christofi N.

J Appl Microbiol. 1999 Oct;87(4):472-80.

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