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Items: 1 to 50 of 75

1.

Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells.

Ahl D, Eriksson O, Sedin J, Seignez C, Schwan E, Kreuger J, Christoffersson G, Phillipson M.

Front Immunol. 2019 Aug 27;10:2036. doi: 10.3389/fimmu.2019.02036. eCollection 2019.

2.

High-Fat Diet Enriched with Bilberry Modifies Colonic Mucus Dynamics and Restores Marked Alterations of Gut Microbiome in Rats.

Liu HY, Walden TB, Ahl D, Nyman M, Bertilsson S, Phillipson M, Holm L.

Mol Nutr Food Res. 2019 Jul 23:e1900117. doi: 10.1002/mnfr.201900117. [Epub ahead of print]

PMID:
31336403
3.

Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition.

Liu HY, Walden TB, Cai D, Ahl D, Bertilsson S, Phillipson M, Nyman M, Holm L.

Nutrients. 2019 Jun 15;11(6). pii: E1350. doi: 10.3390/nu11061350.

4.

The Healing Power of Neutrophils.

Phillipson M, Kubes P.

Trends Immunol. 2019 Jul;40(7):635-647. doi: 10.1016/j.it.2019.05.001. Epub 2019 May 31. Review.

PMID:
31160208
5.

The discovery and development of topical medicines for wound healing.

Öhnstedt E, Lofton Tomenius H, Vågesjö E, Phillipson M.

Expert Opin Drug Discov. 2019 May;14(5):485-497. doi: 10.1080/17460441.2019.1588879. Epub 2019 Mar 14.

PMID:
30870037
6.

Cancer mortality and incidence following external occupational radiation exposure: an update of the 3rd analysis of the UK national registry for radiation workers.

Haylock RGE, Gillies M, Hunter N, Zhang W, Phillipson M.

Br J Cancer. 2018 Aug;119(5):631-637. doi: 10.1038/s41416-018-0184-9. Epub 2018 Aug 15.

7.

The neutrophil: one cell on many missions or many cells with different agendas?

Christoffersson G, Phillipson M.

Cell Tissue Res. 2018 Mar;371(3):415-423. doi: 10.1007/s00441-017-2780-z. Epub 2018 Feb 12. Review.

8.

Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria.

Vågesjö E, Öhnstedt E, Mortier A, Lofton H, Huss F, Proost P, Roos S, Phillipson M.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1895-1900. doi: 10.1073/pnas.1716580115. Epub 2018 Feb 5.

9.

Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer.

Thålin C, Lundström S, Seignez C, Daleskog M, Lundström A, Henriksson P, Helleday T, Phillipson M, Wallén H, Demers M.

PLoS One. 2018 Jan 11;13(1):e0191231. doi: 10.1371/journal.pone.0191231. eCollection 2018.

10.

Vascular sprouts induce local attraction of proangiogenic neutrophils.

Christoffersson G, Lomei J, O'Callaghan P, Kreuger J, Engblom S, Phillipson M.

J Leukoc Biol. 2017 Sep;102(3):741-751. doi: 10.1189/jlb.1MA0117-018R. Epub 2017 Jun 5.

PMID:
28584077
11.

The multitasking neutrophils and their involvement in angiogenesis.

Seignez C, Phillipson M.

Curr Opin Hematol. 2017 Jan;24(1):3-8. Review.

PMID:
27755126
12.

Lactobacillus reuteri increases mucus thickness and ameliorates dextran sulphate sodium-induced colitis in mice.

Ahl D, Liu H, Schreiber O, Roos S, Phillipson M, Holm L.

Acta Physiol (Oxf). 2016 Aug;217(4):300-10. doi: 10.1111/apha.12695. Epub 2016 Apr 30.

PMID:
27096537
13.

In Vivo and In Vitro Detection of Luminescent and Fluorescent Lactobacillus reuteri and Application of Red Fluorescent mCherry for Assessing Plasmid Persistence.

Karimi S, Ahl D, Vågesjö E, Holm L, Phillipson M, Jonsson H, Roos S.

PLoS One. 2016 Mar 22;11(3):e0151969. doi: 10.1371/journal.pone.0151969. eCollection 2016.

14.

Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis.

Kreuger J, Phillipson M.

Nat Rev Drug Discov. 2016 Feb;15(2):125-42. doi: 10.1038/nrd.2015.2. Epub 2015 Nov 27. Review.

PMID:
26612664
15.

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.

Massena S, Christoffersson G, Vågesjö E, Seignez C, Gustafsson K, Binet F, Herrera Hidalgo C, Giraud A, Lomei J, Weström S, Shibuya M, Claesson-Welsh L, Gerwins P, Welsh M, Kreuger J, Phillipson M.

Blood. 2015 Oct 22;126(17):2016-26. doi: 10.1182/blood-2015-03-631572. Epub 2015 Aug 18.

16.

Physiological recycling of endogenous nitrate by oral bacteria regulates gastric mucus thickness.

Petersson J, Jädert C, Phillipson M, Borniquel S, Lundberg JO, Holm L.

Free Radic Biol Med. 2015 Dec;89:241-7. doi: 10.1016/j.freeradbiomed.2015.07.003. Epub 2015 Jul 8.

PMID:
26163002
17.

Matrix metalloproteinase-9 is essential for physiological Beta cell function and islet vascularization in adult mice.

Christoffersson G, Waldén T, Sandberg M, Opdenakker G, Carlsson PO, Phillipson M.

Am J Pathol. 2015 Apr;185(4):1094-103. doi: 10.1016/j.ajpath.2014.12.009. Epub 2015 Feb 7.

PMID:
25665793
18.

Shb deficiency in endothelium but not in leucocytes is responsible for impaired vascular performance during hindlimb ischaemia.

Nikpour M, Gustafsson K, Vågesjö E, Seignez C, Giraud A, Phillipson M, Welsh M.

Acta Physiol (Oxf). 2015 Jun;214(2):200-9. doi: 10.1111/apha.12448. Epub 2015 Jan 17.

PMID:
25561022
19.

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

Li S, Pettersson US, Hoorelbeke B, Kolaczkowska E, Schelfhout K, Martens E, Kubes P, Van Damme J, Phillipson M, Opdenakker G.

PLoS One. 2014 Aug 5;9(8):e104107. doi: 10.1371/journal.pone.0104107. eCollection 2014.

20.

Acute sleep deprivation in healthy young men: impact on population diversity and function of circulating neutrophils.

Christoffersson G, Vågesjö E, Pettersson US, Massena S, Nilsson EK, Broman JE, Schiöth HB, Benedict C, Phillipson M.

Brain Behav Immun. 2014 Oct;41:162-72. doi: 10.1016/j.bbi.2014.05.010. Epub 2014 May 28.

PMID:
24878171
21.

Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease.

Jädert C, Phillipson M, Holm L, Lundberg JO, Borniquel S.

Redox Biol. 2013 Dec 24;2:73-81. doi: 10.1016/j.redox.2013.12.012. eCollection 2014.

22.

Immunological shielding by induced recruitment of regulatory T-lymphocytes delays rejection of islets transplanted in muscle.

Vågesjö E, Christoffersson G, Waldén TB, Carlsson PO, Essand M, Korsgren O, Phillipson M.

Cell Transplant. 2015;24(2):263-76. doi: 10.3727/096368914X678535. Epub 2014 Jan 29.

PMID:
24480306
23.

Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men.

Benedict C, Cedernaes J, Giedraitis V, Nilsson EK, Hogenkamp PS, Vågesjö E, Massena S, Pettersson U, Christoffersson G, Phillipson M, Broman JE, Lannfelt L, Zetterberg H, Schiöth HB.

Sleep. 2014 Jan 1;37(1):195-8. doi: 10.5665/sleep.3336.

24.

iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats.

Schreiber O, Petersson J, Waldén T, Ahl D, Sandler S, Phillipson M, Holm L.

PLoS One. 2013 Aug 19;8(8):e71843. doi: 10.1371/journal.pone.0071843. eCollection 2013.

25.

αB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin.

Dieterich LC, Huang H, Massena S, Golenhofen N, Phillipson M, Dimberg A.

Angiogenesis. 2013 Oct;16(4):975-83. doi: 10.1007/s10456-013-9367-4. Epub 2013 Aug 9.

26.

Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue.

Pettersson US, Waldén TB, Carlsson PO, Jansson L, Phillipson M.

PLoS One. 2012;7(9):e46057. doi: 10.1371/journal.pone.0046057. Epub 2012 Sep 25.

27.

Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction.

Dicksved J, Schreiber O, Willing B, Petersson J, Rang S, Phillipson M, Holm L, Roos S.

PLoS One. 2012;7(9):e46399. doi: 10.1371/journal.pone.0046399. Epub 2012 Sep 27.

28.

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells.

Zang G, Christoffersson G, Tian G, Harun-Or-Rashid M, Vågesjö E, Phillipson M, Barg S, Tengholm A, Welsh M.

Cell Signal. 2013 Jan;25(1):85-92. doi: 10.1016/j.cellsig.2012.09.018. Epub 2012 Sep 18.

PMID:
23000345
29.

VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue.

Christoffersson G, Vågesjö E, Vandooren J, Lidén M, Massena S, Reinert RB, Brissova M, Powers AC, Opdenakker G, Phillipson M.

Blood. 2012 Nov 29;120(23):4653-62. doi: 10.1182/blood-2012-04-421040. Epub 2012 Sep 10.

30.

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

Sun Z, Li X, Massena S, Kutschera S, Padhan N, Gualandi L, Sundvold-Gjerstad V, Gustafsson K, Choy WW, Zang G, Quach M, Jansson L, Phillipson M, Abid MR, Spurkland A, Claesson-Welsh L.

J Exp Med. 2012 Jul 2;209(7):1363-77. doi: 10.1084/jem.20111343. Epub 2012 Jun 11.

31.

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.

Christoffersson G, Zang G, Zhuang ZW, Vågesjö E, Simons M, Phillipson M, Welsh M.

Angiogenesis. 2012 Sep;15(3):469-80. doi: 10.1007/s10456-012-9275-z. Epub 2012 May 5.

32.

Assessment of mucus thickness and production in situ.

Holm L, Phillipson M.

Methods Mol Biol. 2012;842:217-27. doi: 10.1007/978-1-61779-513-8_12.

PMID:
22259138
33.

Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury.

Jädert C, Petersson J, Massena S, Ahl D, Grapensparr L, Holm L, Lundberg JO, Phillipson M.

Free Radic Biol Med. 2012 Feb 1;52(3):683-692. doi: 10.1016/j.freeradbiomed.2011.11.018. Epub 2011 Nov 30.

PMID:
22178413
34.

The neutrophil in vascular inflammation.

Phillipson M, Kubes P.

Nat Med. 2011 Nov 7;17(11):1381-90. doi: 10.1038/nm.2514. Review.

PMID:
22064428
35.

Increased recruitment but impaired function of leukocytes during inflammation in mouse models of type 1 and type 2 diabetes.

Pettersson US, Christoffersson G, Massena S, Ahl D, Jansson L, Henriksnäs J, Phillipson M.

PLoS One. 2011;6(7):e22480. doi: 10.1371/journal.pone.0022480. Epub 2011 Jul 25.

36.

Intramuscular islet transplantation promotes restored islet vascularity.

Christoffersson G, Carlsson PO, Phillipson M.

Islets. 2011 Mar-Apr;3(2):69-71. Epub 2011 Mar 1.

PMID:
21346414
37.

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E, Costa S, Vinckier S, Dresselaer T, Åkerud P, De Mol M, Salomäki H, Phillipson M, Wyns S, Larsson E, Buysschaert I, Botling J, Himmelreich U, Van Ginderachter JA, De Palma M, Dewerchin M, Claesson-Welsh L, Carmeliet P.

Cancer Cell. 2011 Jan 18;19(1):31-44. doi: 10.1016/j.ccr.2010.11.009. Epub 2011 Jan 6.

38.

Importance and regulation of the colonic mucus barrier in a mouse model of colitis.

Petersson J, Schreiber O, Hansson GC, Gendler SJ, Velcich A, Lundberg JO, Roos S, Holm L, Phillipson M.

Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G327-33. doi: 10.1152/ajpgi.00422.2010. Epub 2010 Nov 25.

39.

Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.

Petri B, Kaur J, Long EM, Li H, Parsons SA, Butz S, Phillipson M, Vestweber D, Patel KD, Robbins SM, Kubes P.

Blood. 2011 Jan 20;117(3):942-52. doi: 10.1182/blood-2010-02-270561. Epub 2010 Oct 28.

PMID:
21030556
40.

Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets.

Christoffersson G, Henriksnäs J, Johansson L, Rolny C, Ahlström H, Caballero-Corbalan J, Segersvärd R, Permert J, Korsgren O, Carlsson PO, Phillipson M.

Diabetes. 2010 Oct;59(10):2569-78. doi: 10.2337/db10-0205. Epub 2010 Jul 22.

41.

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils.

Massena S, Christoffersson G, Hjertström E, Zcharia E, Vlodavsky I, Ausmees N, Rolny C, Li JP, Phillipson M.

Blood. 2010 Sep 16;116(11):1924-31. doi: 10.1182/blood-2010-01-266072. Epub 2010 Jun 8.

42.

Secretory cell hyperplasia and defects in Notch activity in a mouse model of leukocyte adhesion deficiency type II.

Waterhouse CC, Johnson S, Phillipson M, Zbytnuik L, Petri B, Kelly M, Lowe JB, Kubes P.

Gastroenterology. 2010 Mar;138(3):1079-90.e1-5. doi: 10.1053/j.gastro.2009.10.049. Epub 2009 Nov 10.

PMID:
19900444
43.

Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature.

Phillipson M, Heit B, Parsons SA, Petri B, Mullaly SC, Colarusso P, Gower RM, Neely G, Simon SI, Kubes P.

J Immunol. 2009 Jun 1;182(11):6870-8. doi: 10.4049/jimmunol.0803414.

44.

Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash.

Petersson J, Carlström M, Schreiber O, Phillipson M, Christoffersson G, Jägare A, Roos S, Jansson EA, Persson AE, Lundberg JO, Holm L.

Free Radic Biol Med. 2009 Apr 15;46(8):1068-75. doi: 10.1016/j.freeradbiomed.2009.01.011. Epub 2009 Jan 21.

PMID:
19439233
45.

Lactobacillus reuteri prevents colitis by reducing P-selectin-associated leukocyte- and platelet-endothelial cell interactions.

Schreiber O, Petersson J, Phillipson M, Perry M, Roos S, Holm L.

Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G534-42. doi: 10.1152/ajpgi.90470.2008. Epub 2009 Jan 15.

46.

Acute effects of Helicobacter pylori extracts on gastric mucosal blood flow in the mouse.

Henriksnäs J, Atuma C, Phillipson M, Sandler S, Engstrand L, Holm L.

World J Gastroenterol. 2009 Jan 14;15(2):219-25.

47.

Cancer in the offspring of female radiation workers: a record linkage study.

Bunch KJ, Muirhead CR, Draper GJ, Hunter N, Kendall GM, O'Hagan JA, Phillipson MA, Vincent TJ, Zhang W.

Br J Cancer. 2009 Jan 13;100(1):213-8. doi: 10.1038/sj.bjc.6604841.

48.

Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers.

Muirhead CR, O'Hagan JA, Haylock RG, Phillipson MA, Willcock T, Berridge GL, Zhang W.

Br J Cancer. 2009 Jan 13;100(1):206-12. doi: 10.1038/sj.bjc.6604825.

49.

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.

Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9. doi: 10.1073/pnas.0803124105. Epub 2008 Sep 19.

50.

The gastric mucus layers: constituents and regulation of accumulation.

Phillipson M, Johansson ME, Henriksnäs J, Petersson J, Gendler SJ, Sandler S, Persson AE, Hansson GC, Holm L.

Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G806-12. doi: 10.1152/ajpgi.90252.2008. Epub 2008 Aug 21.

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