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Items: 1 to 50 of 124


Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles.

Tian Y, Babor M, Lane J, Seumois G, Liang S, Goonawardhana NDS, De Silva AD, Phillips EJ, Mallal SA, da Silva Antunes R, Grifoni A, Vijayanand P, Weiskopf D, Peters B, Sette A.

J Clin Invest. 2019 Mar 18;130. pii: 123726. doi: 10.1172/JCI123726. eCollection 2019 Mar 18.


HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.

Konvinse KC, Trubiano JA, Pavlos R, James I, Shaffer CM, Bejan CA, Schutte RJ, Ostrov DA, Pilkinton MA, Rosenbach M, Zwerner JP, Williams KB, Bourke J, Martinez P, Rwandamuriye F, Chopra A, Watson M, Redwood AJ, White KD, Mallal SA, Phillips EJ.

J Allergy Clin Immunol. 2019 Feb 16. pii: S0091-6749(19)30210-6. doi: 10.1016/j.jaci.2019.01.045. [Epub ahead of print]


Prevention and Diagnosis of Severe T-Cell-Mediated Adverse Drug Reactions: Are We There Yet?

Redwood A, Trubiano J, Phillips EJ.

J Allergy Clin Immunol Pract. 2019 Jan;7(1):228-230. doi: 10.1016/j.jaip.2018.07.011. No abstract available.


Controversies in drug allergy: Testing for delayed reactions.

Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, Lehloenya R, Mockenhaupt M, Peter J, Pirmohamed M, Roujeau JC, Shear NH, Tanno LK, Trubiano J, Valluzzi R, Barbaud A.

J Allergy Clin Immunol. 2019 Jan;143(1):66-73. doi: 10.1016/j.jaci.2018.10.030. Epub 2018 Dec 17. Review.


Antibiotic allergy.

Blumenthal KG, Peter JG, Trubiano JA, Phillips EJ.

Lancet. 2019 Jan 12;393(10167):183-198. doi: 10.1016/S0140-6736(18)32218-9. Epub 2018 Dec 14. Review.


Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized.

Stone CA Jr, Liu Y, Relling MV, Krantz MS, Pratt AL, Abreo A, Hemler JA, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Dec 14. pii: S2213-2198(18)30823-7. doi: 10.1016/j.jaip.2018.12.003. [Epub ahead of print]


The Safety and Efficacy of an Oral Penicillin Challenge Program in Cancer Patients: A Multicenter Pilot Study.

Trubiano JA, Smibert O, Douglas A, Devchand M, Lambros B, Holmes NE, Chua KY, Phillips EJ, Slavin MA.

Open Forum Infect Dis. 2018 Nov 17;5(12):ofy306. doi: 10.1093/ofid/ofy306. eCollection 2018 Dec.


Placement effects of inertial measurement units on contact identification in wheelchair racing.

Lewis AR, Haydon DS, Phillips EJ, Grimshaw PN, Pinder RA, Winter J, Robertson WSP, Portus MR.

Sports Biomech. 2018 Nov 27:1-16. doi: 10.1080/14763141.2018.1522367. [Epub ahead of print]


Precision HIV care: responding to old questions and meeting new challenges.

Hulgan T, Dash C, Haas DW, Phillips EJ.

Pharmacogenomics. 2018 Nov;19(17):1299-1302. doi: 10.2217/pgs-2018-0126. Epub 2018 Oct 16. No abstract available.


The safety of antibiotic skin testing in severe T-cell-mediated hypersensitivity of immunocompetent and immunocompromised hosts.

Trubiano JA, Douglas AP, Goh M, Slavin MA, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Sep 26. pii: S2213-2198(18)30590-7. doi: 10.1016/j.jaip.2018.09.014. [Epub ahead of print] No abstract available.


Pathways to improved antibiotic allergy and antimicrobial stewardship practice: The validation of a beta-lactam antibiotic allergy assessment tool.

Devchand M, Urbancic KF, Khumra S, Douglas AP, Smibert O, Cohen E, Sutherland M, Phillips EJ, Trubiano JA.

J Allergy Clin Immunol Pract. 2019 Mar;7(3):1063-1065.e5. doi: 10.1016/j.jaip.2018.07.048. Epub 2018 Aug 29. No abstract available.


Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions.

Karnes JH, Miller MA, White KD, Konvinse KC, Pavlos RK, Redwood AJ, Peter JG, Lehloenya R, Mallal SA, Phillips EJ.

Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:463-486. doi: 10.1146/annurev-pharmtox-010818-021818. Epub 2018 Aug 22.


Defining Regional Differences in Drug-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Tool to Improve Drug Safety?

Phillips EJ.

Clin Pharmacol Ther. 2019 Jan;105(1):22-25. doi: 10.1002/cpt.1175. Epub 2018 Aug 17. No abstract available.


Antibiotic allergy testing improves antibiotic appropriateness in patients with cancer.

Trubiano JA, Grayson ML, Phillips EJ, Stewardson AJ, Thursky KA, Slavin MA.

J Antimicrob Chemother. 2018 Nov 1;73(11):3209-3211. doi: 10.1093/jac/dky307. No abstract available.


Anaphylaxis after vaccination in a pediatric patient: further implicating alpha-gal allergy.

Stone CA Jr, Commins SP, Choudhary S, Vethody C, Heavrin JL, Wingerter J, Hemler JA, Babe K, Phillips EJ, Norton AE.

J Allergy Clin Immunol Pract. 2019 Jan;7(1):322-324.e2. doi: 10.1016/j.jaip.2018.06.005. Epub 2018 Jun 15. No abstract available.


How antibiotic allergy labels may be harming our most vulnerable patients.

Trubiano JA, Grayson ML, Thursky KA, Phillips EJ, Slavin MA.

Med J Aust. 2018 Jun 18;208(11):469-470. No abstract available.


Minimal clinically important differences for measures of treatment efficacy in Stevens-Johnson syndrome and toxic epidermal necrolysis.

Kim WB, Worley B, Holmes J, Phillips EJ, Beecker J.

J Am Acad Dermatol. 2018 Dec;79(6):1150-1152. doi: 10.1016/j.jaad.2018.06.002. Epub 2018 Jun 8. No abstract available.


Effects of Athlete-Dependent Traits on Joint and System Countermovement-Jump Power.

Williams KJ, Chapman DW, Phillips EJ, Ball N.

Int J Sports Physiol Perform. 2018 Nov 26:1-8. doi: 10.1123/ijspp.2018-0050. [Epub ahead of print]


Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B*57:01 peptide repertoire alteration.

Phillips EJ, Mallal SA.

J Clin Invest. 2018 Jul 2;128(7):2746-2749. doi: 10.1172/JCI121525. Epub 2018 May 21.


Antibiotic Allergy in Pediatrics.

Norton AE, Konvinse K, Phillips EJ, Broyles AD.

Pediatrics. 2018 May;141(5). pii: e20172497. doi: 10.1542/peds.2017-2497. Review.


Antibiotic Use After Removal of Penicillin Allergy Label.

Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Kibicho J, Brousseau DC.

Pediatrics. 2018 May;141(5). pii: e20173466. doi: 10.1542/peds.2017-3466.


Incidence of Nephrotoxicity Among Pediatric Patients Receiving Vancomycin With Either Piperacillin-Tazobactam or Cefepime: A Cohort Study.

Cook KM, Gillon J, Grisso AG, Banerjee R, Jimenez-Truque N, Phillips EJ, Van Driest SL.

J Pediatric Infect Dis Soc. 2018 Mar 26. doi: 10.1093/jpids/piy030. [Epub ahead of print]


Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.

Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL Jr, Mushiroda T, Klein T, Gammal RS, Pirmohamed M.

Clin Pharmacol Ther. 2018 Apr;103(4):574-581. doi: 10.1002/cpt.1004. Epub 2018 Feb 2.



Stone CA Jr, Hemler JA, Commins SP, Schuyler AJ, Phillips EJ, Peebles RS Jr, Fahrenholz JM.

J Allergy Clin Immunol. 2018 May;141(5):1957-1958. doi: 10.1016/j.jaci.2017.08.048. Epub 2018 Jan 19. No abstract available.


Load-Power Relationship During a Countermovement Jump: A Joint Level Analysis.

Williams KJ, Chapman DW, Phillips EJ, Ball NB.

J Strength Cond Res. 2018 Apr;32(4):955-961. doi: 10.1519/JSC.0000000000002432.


SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.

White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH 4th, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):38-69. doi: 10.1016/j.jaip.2017.11.023. Review.


HLAs: Key regulators of T-cell-mediated drug hypersensitivity.

Redwood AJ, Pavlos RK, White KD, Phillips EJ.

HLA. 2018 Jan;91(1):3-16. doi: 10.1111/tan.13183. Review.


Persistence of Penicillin Allergy-Reply.

Trubiano JA, Adkinson NF, Phillips EJ.

JAMA. 2017 Nov 7;318(17):1714-1715. doi: 10.1001/jama.2017.13763. No abstract available.


Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.

Manolio TA, Hutter CM, Avigan M, Cibotti R, Davis RL, Denny JC, Grenade L, Wheatley LM, Carrington MN, Chantratita W, Chung WH, Dalton AD, Hung SI, Lee MTM, Leeder JS, Lertora JJL, Mahasirimongkol S, McLeod HL, Mockenhaupt M, Pacanowski M, Phillips EJ, Pinheiro S, Pirmohamed M, Sung C, Suwankesawong W, Trepanier L, Tumminia SJ, Veenstra D, Yuliwulandari R, Shear NH.

Clin Pharmacol Ther. 2018 Mar;103(3):390-394. doi: 10.1002/cpt.890. Epub 2017 Nov 6.


The Combined Utility of Ex Vivo IFN-γ Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions.

Trubiano JA, Strautins K, Redwood AJ, Pavlos R, Konvinse KC, Aung AK, Slavin MA, Thursky KA, Grayson ML, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1287-1296.e1. doi: 10.1016/j.jaip.2017.09.004. Epub 2017 Oct 31.


Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.

Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA.

J Immunol. 2017 Nov 1;199(9):3187-3201. doi: 10.4049/jimmunol.1700851. Epub 2017 Oct 2.


Severe Delayed Drug Reactions: Role of Genetics and Viral Infections.

Pavlos R, White KD, Wanjalla C, Mallal SA, Phillips EJ.

Immunol Allergy Clin North Am. 2017 Nov;37(4):785-815. doi: 10.1016/j.iac.2017.07.007. Review.


A survey of drug allergy training opportunities in the United States.

Derrick MI, Williams KB, Shade LMP, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):302-304. doi: 10.1016/j.jaip.2017.08.003. Epub 2017 Sep 22. No abstract available.


The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.

Trubiano JA, Stone CA, Grayson ML, Urbancic K, Slavin MA, Thursky KA, Phillips EJ.

J Allergy Clin Immunol Pract. 2017 Nov - Dec;5(6):1532-1542. doi: 10.1016/j.jaip.2017.06.017. Epub 2017 Aug 23. Review. Erratum in: J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):323.


Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles.

Pavlos R, McKinnon EJ, Ostrov DA, Peters B, Buus S, Koelle D, Chopra A, Schutte R, Rive C, Redwood A, Restrepo S, Bracey A, Kaever T, Myers P, Speers E, Malaker SA, Shabanowitz J, Jing Y, Gaudieri S, Hunt DF, Carrington M, Haas DW, Mallal S, Phillips EJ.

Sci Rep. 2017 Aug 17;7(1):8653. doi: 10.1038/s41598-017-08876-0.


Influence of Human Leukocyte Antigen (HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors (KIR) Types on Heparin-Induced Thrombocytopenia (HIT).

Karnes JH, Shaffer CM, Cronin R, Bastarache L, Gaudieri S, James I, Pavlos R, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM.

Pharmacotherapy. 2017 Sep;37(9):1164-1171. doi: 10.1002/phar.1983. Epub 2017 Sep 4.


Penicillin Allergy Is Not Necessarily Forever.

Trubiano JA, Adkinson NF, Phillips EJ.

JAMA. 2017 Jul 4;318(1):82-83. doi: 10.1001/jama.2017.6510. No abstract available.


Cobicistat Versus Ritonavir: Similar Pharmacokinetic Enhancers But Some Important Differences.

Tseng A, Hughes CA, Wu J, Seet J, Phillips EJ.

Ann Pharmacother. 2017 Nov;51(11):1008-1022. doi: 10.1177/1060028017717018. Epub 2017 Jun 19. Review.


Impact of an Integrated Antibiotic Allergy Testing Program on Antimicrobial Stewardship: A Multicenter Evaluation.

Trubiano JA, Thursky KA, Stewardson AJ, Urbancic K, Worth LJ, Jackson C, Stevenson W, Sutherland M, Slavin MA, Grayson ML, Phillips EJ.

Clin Infect Dis. 2017 Jul 1;65(1):166-174. doi: 10.1093/cid/cix244. Review.


Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC.

Sci Transl Med. 2017 May 10;9(389). pii: eaai8708. doi: 10.1126/scitranslmed.aai8708.


Severe Delayed Cutaneous and Systemic Reactions to Drugs: A Global Perspective on the Science and Art of Current Practice.

Peter JG, Lehloenya R, Dlamini S, Risma K, White KD, Konvinse KC, Phillips EJ.

J Allergy Clin Immunol Pract. 2017 May - Jun;5(3):547-563. doi: 10.1016/j.jaip.2017.01.025. Review.


Pharmacogenomics of off-target adverse drug reactions.

Garon SL, Pavlos RK, White KD, Brown NJ, Stone CA Jr, Phillips EJ.

Br J Clin Pharmacol. 2017 Sep;83(9):1896-1911. doi: 10.1111/bcp.13294. Epub 2017 Apr 27. Review.


Recent advances in the understanding of severe cutaneous adverse reactions.

Adler NR, Aung AK, Ergen EN, Trubiano J, Goh MSY, Phillips EJ.

Br J Dermatol. 2017 Nov;177(5):1234-1247. doi: 10.1111/bjd.15423. Epub 2017 Sep 29. Review.


Comparison of HLA allelic imputation programs.

Karnes JH, Shaffer CM, Bastarache L, Gaudieri S, Glazer AM, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM.

PLoS One. 2017 Feb 16;12(2):e0172444. doi: 10.1371/journal.pone.0172444. eCollection 2017.


Anaphylaxis after zoster vaccine: Implicating alpha-gal allergy as a possible mechanism.

Stone CA Jr, Hemler JA, Commins SP, Schuyler AJ, Phillips EJ, Peebles RS Jr, Fahrenholz JM.

J Allergy Clin Immunol. 2017 May;139(5):1710-1713.e2. doi: 10.1016/j.jaci.2016.10.037. Epub 2016 Dec 14. No abstract available.


Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA Jr, Anders RA, Sosman JA, Moslehi JJ.

N Engl J Med. 2016 Nov 3;375(18):1749-1755.


Improving Antimicrobial Stewardship by Antibiotic Allergy Delabeling: Evaluation of Knowledge, Attitude, and Practices Throughout the Emerging Infections Network.

Trubiano JA, Beekmann SE, Worth LJ, Polgreen PM, Thursky KA, Slavin MA, Grayson ML, Phillips EJ.

Open Forum Infect Dis. 2016 Sep 3;3(3):ofw153. eCollection 2016 Sep.


Old dog begging for new tricks: current practices and future directions in the diagnosis of delayed antimicrobial hypersensitivity.

Konvinse KC, Phillips EJ, White KD, Trubiano JA.

Curr Opin Infect Dis. 2016 Dec;29(6):561-576. Review.


Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses.

Jing L, Laing KJ, Dong L, Russell RM, Barlow RS, Haas JG, Ramchandani MS, Johnston C, Buus S, Redwood AJ, White KD, Mallal SA, Phillips EJ, Posavad CM, Wald A, Koelle DM.

J Immunol. 2016 Mar 1;196(5):2205-2218. doi: 10.4049/jimmunol.1502366. Epub 2016 Jan 25.

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