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Items: 26


Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials.

Lucas JS, Gahleitner F, Amorim A, Boon M, Brown P, Constant C, Cook S, Crowley S, Destouches DMS, Eber E, Mussaffi H, Haarman E, Harris A, Koerner-Rettberg C, Kuehni CE, Latzin P, Loebinger MR, Lorent N, Maitre B, Moreno-Galdó A, Nielsen KG, Özçelik U, Philipsen LKD, Pohunek P, Polverino E, Rademacher J, Robinson P, Snijders D, Yiallouros P, Carr SB.

ERJ Open Res. 2019 Feb 1;5(1). pii: 00147-2018. doi: 10.1183/23120541.00147-2018. eCollection 2019 Feb.


CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission.

Heyde S, Philipsen L, Formaglio P, Fu Y, Baars I, Höbbel G, Kleinholz CL, Seiß EA, Stettin J, Gintschel P, Dudeck A, Bousso P, Schraven B, Müller AJ.

PLoS Pathog. 2018 Oct 22;14(10):e1007374. doi: 10.1371/journal.ppat.1007374. eCollection 2018 Oct.


Cold shock Y-box binding protein-1 acetylation status in monocytes is associated with systemic inflammation and vascular damage.

Ewert L, Fischer A, Brandt S, Scurt FG, Philipsen L, Müller AJ, Girndt M, Zenclussen AC, Lindquist JA, Gorny X, Mertens PR.

Atherosclerosis. 2018 Nov;278:156-165. doi: 10.1016/j.atherosclerosis.2018.09.020. Epub 2018 Sep 22.


Multiplexed fluorescence microscopy reveals heterogeneity among stromal cells in mouse bone marrow sections.

Holzwarth K, Köhler R, Philipsen L, Tokoyoda K, Ladyhina V, Wählby C, Niesner RA, Hauser AE.

Cytometry A. 2018 Jul;93(9):876-888. doi: 10.1002/cyto.a.23526. Epub 2018 Aug 14.


JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.

Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T.

J Clin Invest. 2018 Oct 1;128(10):4359-4371. doi: 10.1172/JCI90312. Epub 2018 Jul 19.


The effect of time-of-day and chest physiotherapy on multiple breath washout measures in children with clinically stable cystic fibrosis.

Voldby C, Green K, Rosthøj S, Kongstad T, Philipsen L, Buchvald F, Skov M, Pressler T, Gustafsson P, Nielsen KG.

PLoS One. 2018 Jan 10;13(1):e0190894. doi: 10.1371/journal.pone.0190894. eCollection 2018.


TCR signalling network organization at the immunological synapses of murine regulatory T cells.

van Ham M, Teich R, Philipsen L, Niemz J, Amsberg N, Wissing J, Nimtz M, Gröbe L, Kliche S, Thiel N, Klawonn F, Hubo M, Jonuleit H, Reichardt P, Müller AJ, Huehn J, Jänsch L.

Eur J Immunol. 2017 Dec;47(12):2043-2058. doi: 10.1002/eji.201747041. Epub 2017 Sep 12.


Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1.

Bernhardt A, Fehr A, Brandt S, Jerchel S, Ballhause TM, Philipsen L, Stolze S, Geffers R, Weng H, Fischer KD, Isermann B, Brunner-Weinzierl MC, Batra A, Siegmund B, Zhu C, Lindquist JA, Mertens PR.

Kidney Int. 2017 Nov;92(5):1157-1177. doi: 10.1016/j.kint.2017.03.035. Epub 2017 Jun 11.


Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.

Volckmar J, Gereke M, Ebensen T, Riese P, Philipsen L, Lienenklaus S, Wohlleber D, Klopfleisch R, Stegemann-Koniszewski S, Müller AJ, Gruber AD, Knolle P, Guzman CA, Bruder D.

Sci Rep. 2017 Mar 7;7:43985. doi: 10.1038/srep43985.


De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.

Philipsen L, Reddycherla AV, Hartig R, Gumz J, Kästle M, Kritikos A, Poltorak MP, Prokazov Y, Turbin E, Weber A, Zuschratter W, Schraven B, Simeoni L, Müller AJ.

Sci Signal. 2017 Jan 17;10(462). pii: eaaf4736. doi: 10.1126/scisignal.aaf4736.


D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes.

Witte A, Meineke B, Sticht J, Philipsen L, Kuropka B, Müller AJ, Freund C, Schraven B, Kliche S.

Mol Cell Biol. 2017 Mar 17;37(7). pii: e00509-16. doi: 10.1128/MCB.00509-16. Print 2017 Apr 1.


Immune complexes and complexity: investigating mechanisms of renal disease.

Lindquist JA, Hildebrandt J, Philipsen L, Mertens PR.

Int Urol Nephrol. 2017 Apr;49(4):735-739. doi: 10.1007/s11255-016-1450-5. Epub 2016 Nov 18.


Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation.

Harder T, Guttek K, Philipsen L, Simeoni L, Schraven B, Reinhold D.

Cell Commun Signal. 2014 Dec 8;12:74. doi: 10.1186/s12964-014-0074-6.


Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clusters.

Philipsen L, Engels T, Schilling K, Gurbiel S, Fischer KD, Tedford K, Schraven B, Gunzer M, Reichardt P.

Mol Cell Proteomics. 2013 Sep;12(9):2551-67. doi: 10.1074/mcp.M112.025205. Epub 2013 Jun 10.


T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B.

Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607.


Analysis of TCR activation kinetics in primary human T cells upon focal or soluble stimulation.

Arndt B, Poltorak M, Kowtharapu BS, Reichardt P, Philipsen L, Lindquist JA, Schraven B, Simeoni L.

J Immunol Methods. 2013 Jan 31;387(1-2):276-83. doi: 10.1016/j.jim.2012.11.006. Epub 2012 Nov 22.


Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma.

Berndt U, Philipsen L, Bartsch S, Hu Y, Röcken C, Bertram W, Hämmerle M, Rösch T, Sturm A.

Mol Cancer. 2010 Jul 6;9:177. doi: 10.1186/1476-4598-9-177.


In-situ-topoproteome analysis of cutaneous lymphomas: perspectives of assistance for dermatohistologic diagnostics by Multi Epitope Ligand Cartography (MELC).

Bonnekoh B, Pommer AJ, Böckelmann R, Philipsen L, Hofmeister H, Gollnick H.

J Dtsch Dermatol Ges. 2008 Dec;6(12):1038-51. doi: 10.1111/j.1610-0387.2007.06754.x. English, German.


Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.

Berndt U, Philipsen L, Bartsch S, Wiedenmann B, Baumgart DC, Hämmerle M, Sturm A.

Cancer Res. 2008 Feb 1;68(3):880-8. doi: 10.1158/0008-5472.CAN-07-2923.


Topo-proteomic in situ analysis of psoriatic plaque under efalizumab treatment.

Bonnekoh B, Pommer AJ, Böckelmann R, Hofmeister H, Philipsen L, Gollnick H.

Skin Pharmacol Physiol. 2007;20(5):237-52. Epub 2007 Jun 22.


Proteomic analysis of the inflamed intestinal mucosa reveals distinctive immune response profiles in Crohn's disease and ulcerative colitis.

Berndt U, Bartsch S, Philipsen L, Danese S, Wiedenmann B, Dignass AU, Hämmerle M, Sturm A.

J Immunol. 2007 Jul 1;179(1):295-304.


The CD11a binding site of efalizumab in psoriatic skin tissue as analyzed by Multi-Epitope Ligand Cartography robot technology. Introduction of a novel biological drug-binding biochip assay.

Bonnekoh B, Böckelmann R, Pommer AJ, Malykh Y, Philipsen L, Gollnick H.

Skin Pharmacol Physiol. 2007;20(2):96-111. Epub 2006 Dec 13.


Analyzing proteome topology and function by automated multidimensional fluorescence microscopy.

Schubert W, Bonnekoh B, Pommer AJ, Philipsen L, Böckelmann R, Malykh Y, Gollnick H, Friedenberger M, Bode M, Dress AW.

Nat Biotechnol. 2006 Oct;24(10):1270-8. Epub 2006 Oct 1.


Stability and continuity of child-caregiver and child-peer relationships.

Howes C, Hamilton CE, Phillipsen LC.

Child Dev. 1998 Apr;69(2):418-26. Erratum in: Child Dev 1998 Aug;69(4):872. Philipsen LC [corrected to Phillipsen LC].


[Demonstration of bacteriuria in elderly hospitalized patients. Comparison between leukocyte and nitrite strips and culture].

Madsen OR, Faber M, Philipsen L, Frimodt-Møller N.

Ugeskr Laeger. 1992 Dec 14;154(51):3682-6. Danish.


[Project by 5 student nurses in study course II: we would like to be exposed to a thorough introduction].

Dam KM, Hansen LS, Jensen KA, Nielsen EM, Philipsen LV.

Sygeplejersken. 1979 Sep 26;79(38):12-7. Danish. No abstract available.


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