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Items: 1 to 20 of 108

1.

Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response.

Bobowski-Gerard M, Zummo FP, Staels B, Lefebvre P, Eeckhoute J.

Cells. 2018 Sep 13;7(9). pii: E137. doi: 10.3390/cells7090137.

2.

Stapes Surgery for Otosclerosis in Patients Presenting with Mixed Hearing Loss.

Salmon C, Barriat S, Lefebvre PP.

Audiol Neurootol. 2018 Aug 21;23(2):82-88. doi: 10.1159/000489813. [Epub ahead of print]

PMID:
30130744
3.

The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis.

Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P.

J Hepatol. 2018 Jul 5. pii: S0168-8278(18)32175-5. doi: 10.1016/j.jhep.2018.06.022. [Epub ahead of print]

4.

Tongue Necrosis in Giant-Cell Arteritis.

Truffaut L, Lefebvre P.

N Engl J Med. 2018 Jun 28;378(26):2517. doi: 10.1056/NEJMicm1709412. No abstract available.

5.

Daytime variations in perioperative myocardial injury - Authors' reply.

Montaigne D, Coisne A, Marechal X, Lefebvre P, Staels B.

Lancet. 2018 May 26;391(10135):2106. doi: 10.1016/S0140-6736(18)30758-X. Epub 2018 May 24. No abstract available.

PMID:
29856343
6.

Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle.

Quinault A, Leloup C, Denwood G, Spiegelhalter C, Rodriguez M, Lefebvre P, Messaddeq N, Zhang Q, Dacquet C, Pénicaud L, Collins SC.

PLoS One. 2018 Mar 15;13(3):e0193882. doi: 10.1371/journal.pone.0193882. eCollection 2018.

7.

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.

Montaigne D, Marechal X, Modine T, Coisne A, Mouton S, Fayad G, Ninni S, Klein C, Ortmans S, Seunes C, Potelle C, Berthier A, Gheeraert C, Piveteau C, Deprez R, Eeckhoute J, Duez H, Lacroix D, Deprez B, Jegou B, Koussa M, Edme JL, Lefebvre P, Staels B.

Lancet. 2018 Jan 6;391(10115):59-69. doi: 10.1016/S0140-6736(17)32132-3. Epub 2017 Oct 26.

PMID:
29107324
8.

Organizing combinatorial transcription factor recruitment at cis-regulatory modules.

Dubois-Chevalier J, Mazrooei P, Lupien M, Staels B, Lefebvre P, Eeckhoute J.

Transcription. 2018;9(4):233-239. doi: 10.1080/21541264.2017.1394424. Epub 2017 Nov 28.

PMID:
29105538
9.

The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.

Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, Venteclef N, Pattou F, Staels B, Eeckhoute J, Lefebvre P.

Sci Rep. 2017 Oct 26;7(1):14087. doi: 10.1038/s41598-017-14570-y.

10.

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.

Legry V, Francque S, Haas JT, Verrijken A, Caron S, Chávez-Talavera O, Vallez E, Vonghia L, Dirinck E, Verhaegen A, Kouach M, Lestavel S, Lefebvre P, Van Gaal L, Tailleux A, Paumelle R, Staels B.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3783-3794. doi: 10.1210/jc.2017-01397.

PMID:
28938455
11.

The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.

Vogl C, Butola T, Haag N, Hausrat TJ, Leitner MG, Moutschen M, Lefèbvre PP, Speckmann C, Garrett L, Becker L, Fuchs H, Hrabe de Angelis M, Nietzsche S, Kessels MM, Oliver D, Kneussel M, Kilimann MW, Strenzke N.

EMBO Rep. 2017 Nov;18(11):2015-2029. doi: 10.15252/embr.201643689. Epub 2017 Sep 11.

PMID:
28893864
12.

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.

Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, Vonghia L, Kwanten WJ, Michielsen P, Vanwolleghem T, Eeckhoute J, Verrijken A, Van Gaal L, Francque S, Staels B.

JCI Insight. 2017 Jul 6;2(13). pii: 92264. doi: 10.1172/jci.insight.92264. [Epub ahead of print]

13.

The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.

Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Guillaume P, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, Staels B, Lefebvre P, Eeckhoute J.

Genome Res. 2017 Jun;27(6):985-996. doi: 10.1101/gr.217075.116. Epub 2017 Apr 11.

14.

Distinct but complementary contributions of PPAR isotypes to energy homeostasis.

Dubois V, Eeckhoute J, Lefebvre P, Staels B.

J Clin Invest. 2017 Apr 3;127(4):1202-1214. doi: 10.1172/JCI88894. Epub 2017 Apr 3. Review.

15.

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease.

Chávez-Talavera O, Tailleux A, Lefebvre P, Staels B.

Gastroenterology. 2017 May;152(7):1679-1694.e3. doi: 10.1053/j.gastro.2017.01.055. Epub 2017 Feb 15. Review.

PMID:
28214524
16.

Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.

Le Guével R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G.

ACS Chem Biol. 2017 Mar 17;12(3):654-663. doi: 10.1021/acschembio.6b00593. Epub 2017 Jan 13.

PMID:
28059499
17.

A Retrospective Multicentre Cohort Review of Patient Characteristics and Surgical Aspects versus the Long-Term Outcomes for Recipients of a Fully Implantable Active Middle Ear Implant.

Lefebvre PP, Gisbert J, Cuda D, Tringali S, Deveze A.

Audiol Neurootol. 2016;21(5):333-345. doi: 10.1159/000454666. Epub 2017 Jan 5.

18.

Feasibility of an implanted microphone for cochlear implant listening.

Gérard JM, Demanez L, Salmon C, Vanpoucke F, Walraevens J, Plasmans A, De Siati D, Lefèbvre P.

Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1383-1390. doi: 10.1007/s00405-016-4410-x. Epub 2016 Nov 30.

PMID:
27904958
19.

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.

Gross B, Pawlak M, Lefebvre P, Staels B.

Nat Rev Endocrinol. 2017 Jan;13(1):36-49. doi: 10.1038/nrendo.2016.135. Epub 2016 Sep 16. Review.

PMID:
27636730
20.

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity.

van Moorsel D, Hansen J, Havekes B, Scheer FAJL, Jörgensen JA, Hoeks J, Schrauwen-Hinderling VB, Duez H, Lefebvre P, Schaper NC, Hesselink MKC, Staels B, Schrauwen P.

Mol Metab. 2016 Jul 1;5(8):635-645. doi: 10.1016/j.molmet.2016.06.012. eCollection 2016 Aug.

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