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Items: 1 to 20 of 74

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1.

PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas.

Klein CH, Truxius DC, Vogel HA, Harizanova J, Murarka S, Martín-Gago P, Bastiaens PIH.

Int J Cancer. 2018 Sep 8. doi: 10.1002/ijc.31859. [Epub ahead of print]

PMID:
30194764
2.

Co-imaging extrinsic, intrinsic and effector caspase activity by fluorescence anisotropy microscopy.

Corbat AA, Schuermann KC, Liguzinski P, Radon Y, Bastiaens PIH, Verveer PJ, Grecco HE.

Redox Biol. 2018 Aug 9;19:210-217. doi: 10.1016/j.redox.2018.07.023. [Epub ahead of print]

3.

Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network.

Stanoev A, Mhamane A, Schuermann KC, Grecco HE, Stallaert W, Baumdick M, Brüggemann Y, Joshi MS, Roda-Navarro P, Fengler S, Stockert R, Roßmannek L, Luig J, Koseska A, Bastiaens PIH.

Cell Syst. 2018 Jul 18. pii: S2405-4712(18)30246-1. doi: 10.1016/j.cels.2018.06.006. [Epub ahead of print]

4.

Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling.

Stallaert W, Brüggemann Y, Sabet O, Baak L, Gattiglio M, Bastiaens PIH.

Sci Signal. 2018 Jul 31;11(541). pii: eaat0114. doi: 10.1126/scisignal.aat0114.

PMID:
30065026
5.

Hypertonicity-induced cation channels in HepG2 cells: architecture and role in proliferation vs. apoptosis.

Koos B, Christmann J, Plettenberg S, Käding D, Becker J, Keteku M, Klein C, Imtiaz S, Janning P, Bastiaens PIH, Wehner F.

J Physiol. 2018 Apr 1;596(7):1227-1241. doi: 10.1113/JP275827. Epub 2018 Feb 25.

PMID:
29369356
6.

Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2.

Tsutsumi R, Harizanova J, Stockert R, Schröder K, Bastiaens PIH, Neel BG.

Nat Commun. 2017 Sep 6;8(1):466. doi: 10.1038/s41467-017-00503-w.

7.

Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation.

Konitsiotis AD, Roßmannek L, Stanoev A, Schmick M, Bastiaens PIH.

Nat Commun. 2017 Jul 24;8(1):114. doi: 10.1038/s41467-017-00116-3.

8.

Reversible Cryo-arrests of Living Cells to Pause Molecular Movements for High-resolution Imaging.

Huebinger J, Masip ME, Christmann J, Wehner F, Bastiaens PIH.

Bio Protoc. 2017 Apr 20;7(8). pii: e2236. doi: 10.21769/BioProtoc.2236.

9.

A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2.

Martín-Gago P, Fansa EK, Klein CH, Murarka S, Janning P, Schürmann M, Metz M, Ismail S, Schultz-Fademrecht C, Baumann M, Bastiaens PI, Wittinghofer A, Waldmann H.

Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2423-2428. doi: 10.1002/anie.201610957. Epub 2017 Jan 20.

PMID:
28106325
10.

Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution.

Masip ME, Huebinger J, Christmann J, Sabet O, Wehner F, Konitsiotis A, Fuhr GR, Bastiaens PIH.

Nat Methods. 2016 Aug;13(8):665-672. doi: 10.1038/nmeth.3921. Epub 2016 Jul 11.

11.

Identification of pyrazolopyridazinones as PDEδ inhibitors.

Papke B, Murarka S, Vogel HA, Martín-Gago P, Kovacevic M, Truxius DC, Fansa EK, Ismail S, Zimmermann G, Heinelt K, Schultz-Fademrecht C, Al Saabi A, Baumann M, Nussbaumer P, Wittinghofer A, Waldmann H, Bastiaens PI.

Nat Commun. 2016 Apr 20;7:11360. doi: 10.1038/ncomms11360.

12.

EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.

Baumdick M, Brüggemann Y, Schmick M, Xouri G, Sabet O, Davis L, Chin JW, Bastiaens PI.

Elife. 2015 Nov 26;4. pii: e12223. doi: 10.7554/eLife.12223.

13.

Adaptive responses of cell hydration to a low temperature arrest.

Christmann J, Azer L, Dörr D, Fuhr GR, Bastiaens PI, Wehner F.

J Physiol. 2016 Mar 15;594(6):1663-76. doi: 10.1113/JP271245. Epub 2015 Dec 22.

14.

Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits.

Ibach J, Radon Y, Gelléri M, Sonntag MH, Brunsveld L, Bastiaens PI, Verveer PJ.

PLoS One. 2015 Nov 17;10(11):e0143162. doi: 10.1371/journal.pone.0143162. eCollection 2015.

15.

Direct Measurement of Water States in Cryopreserved Cells Reveals Tolerance toward Ice Crystallization.

Huebinger J, Han HM, Hofnagel O, Vetter IR, Bastiaens PI, Grabenbauer M.

Biophys J. 2016 Feb 23;110(4):840-9. doi: 10.1016/j.bpj.2015.09.029. Epub 2015 Nov 2.

16.

Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode.

Sabet O, Stockert R, Xouri G, Brüggemann Y, Stanoev A, Bastiaens PI.

Nat Commun. 2015 Aug 21;6:8047. doi: 10.1038/ncomms9047.

17.

The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.

Nakhaei-Rad S, Nakhaeizadeh H, Kordes C, Cirstea IC, Schmick M, Dvorsky R, Bastiaens PI, Häussinger D, Ahmadian MR.

J Biol Chem. 2015 Jun 19;290(25):15892-903. doi: 10.1074/jbc.M115.640607. Epub 2015 May 4.

18.

Ras moves to stay in place.

Schmick M, Kraemer A, Bastiaens PI.

Trends Cell Biol. 2015 Apr;25(4):190-7. doi: 10.1016/j.tcb.2015.02.004. Epub 2015 Mar 8.

PMID:
25759176
19.

miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL.

Berg V, Rusch M, Vartak N, Jüngst C, Schauss A, Waldmann H, Hedberg C, Pallasch CP, Bastiaens PI, Hallek M, Wendtner CM, Frenzel LP.

Blood. 2015 May 7;125(19):2948-57. doi: 10.1182/blood-2014-07-586511. Epub 2015 Feb 10.

20.

KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport.

Schmick M, Vartak N, Papke B, Kovacevic M, Truxius DC, Rossmannek L, Bastiaens PIH.

Cell. 2014 Apr 10;157(2):459-471. doi: 10.1016/j.cell.2014.02.051.

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