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J Cell Biol. 2018 Oct 10. pii: jcb.201810022. doi: 10.1083/jcb.201810022. [Epub ahead of print]

A tent pole twist on membrane ruffles.

Author information

1
University of Toronto, Toronto, Canada.

Abstract

Macropinocytosis or "cell drinking" involves the elaboration of membrane ruffles that enclose and internalize extracellular fluids. Using lattice light sheet microscopy, Condon et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201804137) reveal the presence of parallel membrane protrusions termed "tent poles" that flank and direct membrane ruffle formation.

PMID:
30305313
DOI:
10.1083/jcb.201810022

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