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Items: 22

1.

Development of a Selection Method for Discovering Irreversible (Covalent) Binders from a DNA-Encoded Library.

Zhu Z, Grady LC, Ding Y, Lind KE, Davie CP, Phelps CB, Evindar G.

SLAS Discov. 2019 Feb;24(2):169-174. doi: 10.1177/2472555218808454. Epub 2018 Nov 1.

PMID:
30383465
2.

Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, Coffin A, Davie CP, Deng H, Deng J, Ding Y, Dodson JW, Fosbenner DT, Gao EN, Graham TL, Graybill TL, Ingraham K, Johnson WP, King BW, Kwiatkowski CR, Lelièvre J, Li Y, Liu X, Lu Q, Lehr R, Mendoza-Losana A, Martin J, McCloskey L, McCormick P, O'Keefe HP, O'Keeffe T, Pao C, Phelps CB, Qi H, Rafferty K, Scavello GS, Steiginga MS, Sundersingh FS, Sweitzer SM, Szewczuk LM, Taylor A, Fern Toh M, Wang J, Wang M, Wilkins DJ, Xia B, Yao G, Zhang J, Zhou J, Donahue CP, Messer JA, Holmes D, Arico-Muendel CC, Pope AJ, Gross JW, Evindar G.

Nat Commun. 2018 Jul 13;9:16227. doi: 10.1038/ncomms16227.

3.

Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox.

Leveridge M, Chung CW, Gross JW, Phelps CB, Green D.

SLAS Discov. 2018 Oct;23(9):881-897. doi: 10.1177/2472555218778503. Epub 2018 Jun 6. Review.

PMID:
29874524
4.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, Coffin A, Davie CP, Deng H, Deng J, Ding Y, Dodson JW, Fosbenner DT, Gao EN, Graham TL, Graybill TL, Ingraham K, Johnson WP, King BW, Kwiatkowski CR, Lelièvre J, Li Y, Liu X, Lu Q, Lehr R, Mendoza-Losana A, Martin J, McCloskey L, McCormick P, O'Keefe HP, O'Keeffe T, Pao C, Phelps CB, Qi H, Rafferty K, Scavello GS, Steiginga MS, Sundersingh FS, Sweitzer SM, Szewczuk LM, Taylor A, Toh MF, Wang J, Wang M, Wilkins DJ, Xia B, Yao G, Zhang J, Zhou J, Donahue CP, Messer JA, Holmes D, Arico-Muendel CC, Pope AJ, Gross JW, Evindar G.

Nat Commun. 2017 Jul 17;8:16081. doi: 10.1038/ncomms16081. Erratum in: Nat Commun. 2018 Jul 13;9:16227.

5.

Ruthenium Promoted On-DNA Ring-Closing Metathesis and Cross-Metathesis.

Lu X, Fan L, Phelps CB, Davie CP, Donahue CP.

Bioconjug Chem. 2017 Jun 21;28(6):1625-1629. doi: 10.1021/acs.bioconjchem.7b00292. Epub 2017 Jun 9.

PMID:
28581718
6.

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.

Landouré G, Zdebik AA, Martinez TL, Burnett BG, Stanescu HC, Inada H, Shi Y, Taye AA, Kong L, Munns CH, Choo SS, Phelps CB, Paudel R, Houlden H, Ludlow CL, Caterina MJ, Gaudet R, Kleta R, Fischbeck KH, Sumner CJ.

Nat Genet. 2010 Feb;42(2):170-4. doi: 10.1038/ng.512. Epub 2009 Dec 27.

7.

Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.

Phelps CB, Wang RR, Choo SS, Gaudet R.

J Biol Chem. 2010 Jan 1;285(1):731-40. doi: 10.1074/jbc.M109.052548. Epub 2009 Oct 28.

8.

Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat diet.

Reynolds TH 4th, Cinquino N, Anthony M, Phelps CB, Zachary Berk E.

J Appl Physiol (1985). 2009 Nov;107(5):1479-85. doi: 10.1152/japplphysiol.00574.2009. Epub 2009 Sep 3. Erratum in: J Appl Physiol. 2011 Aug;111(2):623.. Dosage error in article text.

9.

Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice.

Miller AM, Brestoff JR, Phelps CB, Berk EZ, Reynolds TH 4th.

Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1431-8. doi: 10.1152/ajpregu.90428.2008. Epub 2008 Sep 3. Erratum in: Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R558. Dosage error in article text.

10.

Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels.

Phelps CB, Procko E, Lishko PV, Wang RR, Gaudet R.

Channels (Austin). 2007 May-Jun;1(3):148-51. Epub 2007 Jul 9.

PMID:
18690026
11.

Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels.

Phelps CB, Huang RJ, Lishko PV, Wang RR, Gaudet R.

Biochemistry. 2008 Feb 26;47(8):2476-84. doi: 10.1021/bi702109w. Epub 2008 Jan 31.

12.

The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization.

Phelps CB, Gaudet R.

J Biol Chem. 2007 Dec 14;282(50):36474-80. Epub 2007 Oct 1.

13.

The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity.

Lishko PV, Procko E, Jin X, Phelps CB, Gaudet R.

Neuron. 2007 Jun 21;54(6):905-18.

14.

folded gastrulation, cell shape change and the control of myosin localization.

Dawes-Hoang RE, Parmar KM, Christiansen AE, Phelps CB, Brand AH, Wieschaus EF.

Development. 2005 Sep;132(18):4165-78.

15.

Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB.

Huang DB, Phelps CB, Fusco AJ, Ghosh G.

J Mol Biol. 2005 Feb 11;346(1):147-60. Epub 2004 Dec 13.

PMID:
15663934
18.

Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation.

Huxford T, Mishler D, Phelps CB, Huang DB, Sengchanthalangsy LL, Reeves R, Hughes CA, Komives EA, Ghosh G.

J Mol Biol. 2002 Dec 6;324(4):587-97.

PMID:
12460563
19.

X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2.

Huang DB, Chen YQ, Ruetsche M, Phelps CB, Ghosh G.

Structure. 2001 Aug;9(8):669-78.

20.

Mechanism of I kappa B alpha binding to NF-kappa B dimers.

Phelps CB, Sengchanthalangsy LL, Huxford T, Ghosh G.

J Biol Chem. 2000 Sep 22;275(38):29840-6.

21.

Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers.

Phelps CB, Sengchanthalangsy LL, Malek S, Ghosh G.

J Biol Chem. 2000 Aug 11;275(32):24392-9.

22.

Ectopic gene expression in Drosophila using GAL4 system.

Phelps CB, Brand AH.

Methods. 1998 Apr;14(4):367-79. Review.

PMID:
9608508

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