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Items: 19


Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.

Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ.

Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27.


An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, Barres BA, Wu JQ.

J Neurosci. 2014 Sep 3;34(36):11929-47. doi: 10.1523/JNEUROSCI.1860-14.2014. Erratum in: J Neurosci. 2015 Jan 14;35(2):846-6.


A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.

Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T.

Cell Rep. 2013 Jul 25;4(2):385-401. doi: 10.1016/j.celrep.2013.06.018. Epub 2013 Jul 11.


Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Sci Transl Med. 2013 Jun 5;5(188):188le2. doi: 10.1126/scitranslmed.3005065.


Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, Shaw CE, Finkbeiner S, Chandran S.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4697-702. doi: 10.1073/pnas.1300398110. Epub 2013 Feb 11.


Intricate interplay between astrocytes and motor neurons in ALS.

Phatnani HP, Guarnieri P, Friedman BA, Carrasco MA, Muratet M, O'Keeffe S, Nwakeze C, Pauli-Behn F, Newberry KM, Meadows SK, Tapia JC, Myers RM, Maniatis T.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E756-65. doi: 10.1073/pnas.1222361110. Epub 2013 Feb 6.


Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26.


Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.

Möller A, Xie SQ, Hosp F, Lang B, Phatnani HP, James S, Ramirez F, Collin GB, Naggert JK, Babu MM, Greenleaf AL, Selbach M, Pombo A.

Mol Cell Proteomics. 2012 Jun;11(6):M111.011767. doi: 10.1074/mcp.M111.011767. Epub 2011 Dec 22.


CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.

Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL.

Genes Dev. 2010 Oct 15;24(20):2303-16. doi: 10.1101/gad.1968210.


The phosphoCTD-interacting domain of Topoisomerase I.

Wu J, Phatnani HP, Hsieh TS, Greenleaf AL.

Biochem Biophys Res Commun. 2010 Jun 18;397(1):117-9. doi: 10.1016/j.bbrc.2010.05.081. Epub 2010 May 20.


Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

Bennett CB, Westmoreland TJ, Verrier CS, Blanchette CA, Sabin TL, Phatnani HP, Mishina YV, Huper G, Selim AL, Madison ER, Bailey DD, Falae AI, Galli A, Olson JA, Greenleaf AL, Marks JR.

PLoS One. 2008 Jan 16;3(1):e1448. doi: 10.1371/journal.pone.0001448.


Phosphorylation and functions of the RNA polymerase II CTD.

Phatnani HP, Greenleaf AL.

Genes Dev. 2006 Nov 1;20(21):2922-36. Review.


NMR assignment of the SRI domain of human Set2/HYPB.

Li M, Phatnani HP, Greenleaf AL, Zhou P.

J Biomol NMR. 2006;36 Suppl 1:5. No abstract available.


Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.

Li M, Phatnani HP, Guan Z, Sage H, Greenleaf AL, Zhou P.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17636-41. Epub 2005 Nov 28.


A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.

Kizer KO, Phatnani HP, Shibata Y, Hall H, Greenleaf AL, Strahl BD.

Mol Cell Biol. 2005 Apr;25(8):3305-16.


C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.

Jones JC, Phatnani HP, Haystead TA, MacDonald JA, Alam SM, Greenleaf AL.

J Biol Chem. 2004 Jun 11;279(24):24957-64. Epub 2004 Mar 26.


Identifying phosphoCTD-associating proteins.

Phatnani HP, Greenleaf AL.

Methods Mol Biol. 2004;257:17-28.


Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation.

Morris DP, Phatnani HP, Greenleaf AL.

J Biol Chem. 1999 Oct 29;274(44):31583-7.

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