Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 159

1.

Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains.

Ma Y, Iida K, Sasaki S, Hirokawa T, Heddi B, Phan AT, Nagasawa K.

Molecules. 2019 Jan 11;24(2). pii: E263. doi: 10.3390/molecules24020263.

2.

Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.

Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT.

Nucleic Acids Res. 2018 Dec 15. doi: 10.1093/nar/gky1179. [Epub ahead of print]

PMID:
30551210
3.

A Minimal Sequence for Left-Handed G-Quadruplex Formation.

Bakalar B, Heddi B, Schmitt E, Mechulam Y, Phan AT.

Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2331-2335. doi: 10.1002/anie.201812628. Epub 2019 Jan 21.

PMID:
30481397
4.

Effect of Lanreotide Depot/Autogel on Urinary 5-Hydroxyindoleacetic Acid and Plasma Chromogranin A Biomarkers in Nonfunctional Metastatic Enteropancreatic Neuroendocrine Tumors.

Pavel ME, Phan AT, Wolin EM, Mirakhur B, Liyanage N, Pitman Lowenthal S, Fisher GA Jr, Vinik AI; CLARINET Study Investigators.

Oncologist. 2018 Oct 24. pii: theoncologist.2018-0217. doi: 10.1634/theoncologist.2018-0217. [Epub ahead of print]

PMID:
30355775
5.

A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids.

Nadai M, Doria F, Scalabrin M, Pirota V, Grande V, Bergamaschi G, Amendola V, Winnerdy FR, Phan AT, Richter SN, Freccero M.

J Am Chem Soc. 2018 Nov 7;140(44):14528-14532. doi: 10.1021/jacs.8b05337. Epub 2018 Oct 29.

6.

Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop.

Butovskaya E, Heddi B, Bakalar B, Richter SN, Phan AT.

J Am Chem Soc. 2018 Oct 24;140(42):13654-13662. doi: 10.1021/jacs.8b05332. Epub 2018 Oct 9.

7.

Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool.

Zhou Y, Bond AM, Shade JE, Zhu Y, Davis CO, Wang X, Su Y, Yoon KJ, Phan AT, Chen WJ, Oh JH, Marsh-Armstrong N, Atabai K, Ming GL, Song H.

Cell Stem Cell. 2018 Sep 6;23(3):444-452.e4. doi: 10.1016/j.stem.2018.08.005. Epub 2018 Aug 30.

PMID:
30174295
8.

Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound.

Sedghi Masoud S, Yamaoki Y, Ma Y, Marchand A, Winnerdy FR, Gabelica V, Phan AT, Katahira M, Nagasawa K.

Chembiochem. 2018 Nov 2;19(21):2268-2272. doi: 10.1002/cbic.201800425. Epub 2018 Oct 12.

PMID:
30160816
9.

BIOCHEMICAL RESPONSES IN SYMPTOMATIC AND ASYMPTOMATIC PATIENTS WITH NEUROENDOCRINE TUMORS: POOLED ANALYSIS OF 2 PHASE 3 TRIALS.

Mirakhur B, Pavel ME, Pommier RF, Fisher GA, Phan AT, Massien C, Liyanage N, Lowenthal SP, Vinik AI.

Endocr Pract. 2018 Aug 7. doi: 10.4158/EP-2018-0296. [Epub ahead of print]

PMID:
30084687
10.

Two birds, one stone: hesperetin alleviates chemotherapy-induced diarrhea and potentiates tumor inhibition.

Yu Y, Kong R, Cao H, Yin Z, Liu J, Nan X, Phan AT, Ding T, Zhao H, Wong STC.

Oncotarget. 2018 Feb 23;9(46):27958-27973. doi: 10.18632/oncotarget.24563. eCollection 2018 Jun 15.

11.

High-resolution AFM structure of DNA G-wires in aqueous solution.

Bose K, Lech CJ, Heddi B, Phan AT.

Nat Commun. 2018 May 17;9(1):1959. doi: 10.1038/s41467-018-04016-y.

12.

Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.

Asamitsu S, Obata S, Phan AT, Hashiya K, Bando T, Sugiyama H.

Chemistry. 2018 Mar 20;24(17):4428-4435. doi: 10.1002/chem.201705945. Epub 2018 Feb 26.

PMID:
29380465
13.

Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours.

Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW.

Nature. 2018 Feb 15;554(7692):392. doi: 10.1038/nature25445. Epub 2018 Jan 10.

PMID:
29320476
14.

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours.

Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW.

Nature. 2017 Dec 14;552(7684):253-257. doi: 10.1038/nature24993. Epub 2017 Dec 6. Erratum in: Nature. 2018 Jan 10;:.

15.

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.

Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS.

Cancer Cell. 2017 Nov 13;32(5):669-683.e5. doi: 10.1016/j.ccell.2017.10.003.

16.

A Dual-Specific Targeting Approach Based on the Simultaneous Recognition of Duplex and Quadruplex Motifs.

Nguyen TQN, Lim KW, Phan AT.

Sci Rep. 2017 Sep 20;7(1):11969. doi: 10.1038/s41598-017-10583-9.

17.

Budget impact of somatostatin analogs as treatment for metastatic gastroenteropancreatic neuroendocrine tumors in US hospitals.

Ortendahl JD, Pulgar SJ, Mirakhur B, Cox D, Bentley TG, Phan AT.

Clinicoecon Outcomes Res. 2017 Aug 16;9:495-503. doi: 10.2147/CEOR.S140866. eCollection 2017.

18.

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR 3rd, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT.

J Clin Invest. 2017 Oct 2;127(10):3609-3623. doi: 10.1172/JCI90895. Epub 2017 Aug 28.

19.

Rotation of Guanine Amino Groups in G-Quadruplexes: A Probe for Local Structure and Ligand Binding.

Adrian M, Winnerdy FR, Heddi B, Phan AT.

Biophys J. 2017 Aug 22;113(4):775-784. doi: 10.1016/j.bpj.2017.05.053.

20.

Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae.

Piazza A, Cui X, Adrian M, Samazan F, Heddi B, Phan AT, Nicolas AG.

Elife. 2017 Jun 29;6. pii: e26884. doi: 10.7554/eLife.26884.

21.

Recent advances in the management of gastroenteropancreatic neuroendocrine tumors: Discussion.

Iyer R, Phan AT, Boudreaux JP.

Clin Adv Hematol Oncol. 2017 Apr;15 Suppl 4(4):18-19. No abstract available.

PMID:
28654026
22.

Emerging treatment options for patients with gastroenteropancreatic neuroendocrine tumors.

Phan AT.

Clin Adv Hematol Oncol. 2017 Apr;15 Suppl 4(4):10-14. No abstract available.

PMID:
28654024
23.
24.

Estrogen Replacement Reduces Risk and Increases Survival Times of Women With Hepatocellular Carcinoma.

Hassan MM, Botrus G, Abdel-Wahab R, Wolff RA, Li D, Tweardy D, Phan AT, Hawk E, Javle M, Lee JS, Torres HA, Rashid A, Lenzi R, Hassabo HM, Abaza Y, Shalaby AS, Lacin S, Morris J, Patt YZ, Amos CI, Khaderi SA, Goss JA, Jalal PK, Kaseb AO.

Clin Gastroenterol Hepatol. 2017 Nov;15(11):1791-1799. doi: 10.1016/j.cgh.2017.05.036. Epub 2017 Jun 1.

25.

RNA-seq detects pharmacological inhibition of Epstein-Barr virus late transcription during spontaneous reactivation.

Phan AT, Martinez DM, Miranda JL.

Genom Data. 2017 May 12;13:5-6. doi: 10.1016/j.gdata.2017.05.012. eCollection 2017 Sep.

26.

G-quadruplex structure of an anti-proliferative DNA sequence.

Do NQ, Chung WJ, Truong THA, Heddi B, Phan AT.

Nucleic Acids Res. 2017 Jul 7;45(12):7487-7493. doi: 10.1093/nar/gkx274.

27.

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity.

Phan AT, Goldrath AW, Glass CK.

Immunity. 2017 May 16;46(5):714-729. doi: 10.1016/j.immuni.2017.04.016. Review.

28.

Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification.

Lech CJ, Phan AT.

Nucleic Acids Res. 2017 Jun 20;45(11):6265-6274. doi: 10.1093/nar/gkx243.

29.

Leukapheresis reduces 4-week mortality in acute myeloid leukemia patients with hyperleukocytosis - a retrospective study from a tertiary center.

Nan X, Qin Q, Gentille C, Ensor J, Leveque C, Pingali SR, Phan AT, Rice L, Iyer S.

Leuk Lymphoma. 2017 Sep;58(9):1-11. doi: 10.1080/10428194.2016.1277386. Epub 2017 Jan 31.

PMID:
28140714
30.

Neuroendocrine Tumors and Lanreotide Depot: Clinical Considerations and Nurse and Patient Preferences.

Ryan P, Phan AT, Adelman DT, Iwasaki M.

Clin J Oncol Nurs. 2016 Dec 1;20(6):E139-E146. Review.

PMID:
27857269
31.

Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection.

Phan AT, Doedens AL, Palazon A, Tyrakis PA, Cheung KP, Johnson RS, Goldrath AW.

Immunity. 2016 Nov 15;45(5):1024-1037. doi: 10.1016/j.immuni.2016.10.017. Epub 2016 Nov 8.

32.

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.

Tyrakis PA, Palazon A, Macias D, Lee KL, Phan AT, Veliça P, You J, Chia GS, Sim J, Doedens A, Abelanet A, Evans CE, Griffiths JR, Poellinger L, Goldrath AW, Johnson RS.

Nature. 2016 Dec 8;540(7632):236-241. doi: 10.1038/nature20165. Epub 2016 Oct 26.

33.

The pivotal role of mammalian target of rapamycin inhibition in the treatment of patients with neuroendocrine tumors.

Phan AT, Dave B.

Cancer Med. 2016 Oct;5(10):2953-2964. doi: 10.1002/cam4.742. Epub 2016 Aug 18. Review.

34.

Lanreotide Depot: An Antineoplastic Treatment of Carcinoid or Neuroendocrine Tumors.

Wolin EM, Manon A, Chassaing C, Lewis A, Bertocchi L, Richard J, Phan AT.

J Gastrointest Cancer. 2016 Dec;47(4):366-374. Review.

35.

Important Variation in Vibrational Properties of LiFePO4 and FePO4 Induced by Magnetism.

Seifitokaldani A, Gheribi AE, Phan AT, Chartrand P, Dollé M.

Sci Rep. 2016 Sep 8;6:33033. doi: 10.1038/srep33033.

36.

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.

Clever D, Roychoudhuri R, Constantinides MG, Askenase MH, Sukumar M, Klebanoff CA, Eil RL, Hickman HD, Yu Z, Pan JH, Palmer DC, Phan AT, Goulding J, Gattinoni L, Goldrath AW, Belkaid Y, Restifo NP.

Cell. 2016 Aug 25;166(5):1117-1131.e14. doi: 10.1016/j.cell.2016.07.032.

37.

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome.

De Nicola B, Lech CJ, Heddi B, Regmi S, Frasson I, Perrone R, Richter SN, Phan AT.

Nucleic Acids Res. 2016 Jul 27;44(13):6442-51. doi: 10.1093/nar/gkw432. Epub 2016 Jun 13.

38.

Epstein-Barr virus latency type and spontaneous reactivation predict lytic induction levels.

Phan AT, Fernandez SG, Somberg JJ, Keck KM, Miranda JL.

Biochem Biophys Res Commun. 2016 May 20;474(1):71-75. doi: 10.1016/j.bbrc.2016.04.070. Epub 2016 Apr 16.

39.

Anti-tumour effects of lanreotide for pancreatic and intestinal neuroendocrine tumours: the CLARINET open-label extension study.

Caplin ME, Pavel M, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, Cadiot G, Wolin EM, Capdevila J, Wall L, Rindi G, Langley A, Martinez S, Gomez-Panzani E, Ruszniewski P; CLARINET Investigators.

Endocr Relat Cancer. 2016 Mar;23(3):191-9. doi: 10.1530/ERC-15-0490. Epub 2016 Jan 7.

40.

G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule binding.

Heddi B, Martín-Pintado N, Serimbetov Z, Kari TM, Phan AT.

Nucleic Acids Res. 2016 Jan 29;44(2):910-6. doi: 10.1093/nar/gkv1357. Epub 2015 Dec 15.

41.

Correction to Formation of a Stacked Dimeric G-Quadruplex Containing Bulges by the 5'-Terminal Region of Human Telomerase RNA (hTERC).

Martadinata H, Phan AT.

Biochemistry. 2015 Dec 8;54(48):7156. doi: 10.1021/acs.biochem.5b01231. Epub 2015 Nov 25. No abstract available.

PMID:
26616480
42.

Inverting the G-Tetrad Polarity of a G-Quadruplex by Using Xanthine and 8-Oxoguanine.

Cheong VV, Lech CJ, Heddi B, Phan AT.

Angew Chem Int Ed Engl. 2016 Jan 4;55(1):160-3. doi: 10.1002/anie.201507034. Epub 2015 Nov 13.

PMID:
26563582
43.

Development of Fluorescent Protein Probes Specific for Parallel DNA and RNA G-Quadruplexes.

Dang DT, Phan AT.

Chembiochem. 2016 Jan 1;17(1):42-5. doi: 10.1002/cbic.201500503. Epub 2015 Dec 9.

PMID:
26548353
44.

Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.

Crumley SM, Pepper KL, Phan AT, Olsen RJ, Schwartz MR, Portier BP.

Arch Pathol Lab Med. 2016 Jun;140(6):529-35. doi: 10.5858/arpa.2015-0261-SA. Epub 2015 Nov 4.

PMID:
26536055
45.

New and Emerging Treatment Options for Gastroenteropancreatic Neuroendocrine Tumors.

Phan AT, Kunz PL, Reidy-Lagunes DL.

Clin Adv Hematol Oncol. 2015 May;13(5 Suppl 5):1-18; quiz 1 p following 18.

PMID:
26430956
46.

Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G·G·X·O tetrad.

Cheong VV, Heddi B, Lech CJ, Phan AT.

Nucleic Acids Res. 2015 Dec 2;43(21):10506-14. doi: 10.1093/nar/gkv826. Epub 2015 Sep 22.

47.

Hypoxia-inducible factors regulate T cell metabolism and function.

Phan AT, Goldrath AW.

Mol Immunol. 2015 Dec;68(2 Pt C):527-35. doi: 10.1016/j.molimm.2015.08.004. Epub 2015 Aug 19. Review.

48.

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex.

Heddi B, Cheong VV, Martadinata H, Phan AT.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9608-13. doi: 10.1073/pnas.1422605112. Epub 2015 Jul 20.

49.

Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain.

Sun GJ, Zhou Y, Stadel RP, Moss J, Yong JH, Ito S, Kawasaki NK, Phan AT, Oh JH, Modak N, Reed RR, Toni N, Song H, Ming GL.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9484-9. doi: 10.1073/pnas.1508545112. Epub 2015 Jul 13.

50.

Duplex stem-loop-containing quadruplex motifs in the human genome: a combined genomic and structural study.

Lim KW, Jenjaroenpun P, Low ZJ, Khong ZJ, Ng YS, Kuznetsov VA, Phan AT.

Nucleic Acids Res. 2015 Jun 23;43(11):5630-46. doi: 10.1093/nar/gkv355. Epub 2015 May 9.

Supplemental Content

Support Center