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Items: 1 to 50 of 64

1.

Simultaneous targeting of XPO1 and BCL2 as an effective treatment strategy for double-hit lymphoma.

Liu Y, Azizian NG, Dou Y, Pham LV, Li Y.

J Hematol Oncol. 2019 Nov 21;12(1):119. doi: 10.1186/s13045-019-0803-9.

2.

DNA-HPV transition rate and related factors in HPV-infected women in Can Tho city, Vietnam.

Duong LM, Pham LV, Pham TT, Tran DN, Bui NQ, Tran HD, Vo TH.

Trop Med Int Health. 2019 Nov;24(11):1330-1334. doi: 10.1111/tmi.13309. Epub 2019 Oct 3.

PMID:
31520562
3.

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma.

Zhang L, Yao Y, Zhang S, Liu Y, Guo H, Ahmed M, Bell T, Zhang H, Han G, Lorence E, Badillo M, Zhou S, Sun Y, Di Francesco ME, Feng N, Haun R, Lan R, Mackintosh SG, Mao X, Song X, Zhang J, Pham LV, Lorenzi PL, Marszalek J, Heffernan T, Draetta G, Jones P, Futreal A, Nomie K, Wang L, Wang M.

Sci Transl Med. 2019 May 8;11(491). pii: eaau1167. doi: 10.1126/scitranslmed.aau1167.

PMID:
31068440
4.

Upright posture increases oxyhemoglobin saturation in Peruvian highlanders.

Arias RS, Etienne B, Polotsky VY, Checkley W, Schwartz AR, Pham LV.

Respir Physiol Neurobiol. 2019 Aug;266:138-143. doi: 10.1016/j.resp.2019.04.015. Epub 2019 May 24.

PMID:
31048020
5.

Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).

Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H.

J Autoimmun. 2019 Aug;102:77-88. doi: 10.1016/j.jaut.2019.04.020. Epub 2019 Apr 26.

PMID:
31036429
6.

Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.

Jensen SB, Fahnøe U, Pham LV, Serre SBN, Tang Q, Ghanem L, Pedersen MS, Ramirez S, Humes D, Pihl AF, Filskov J, Sølund CS, Dietz J, Fourati S, Pawlotsky JM, Sarrazin C, Weis N, Schønning K, Krarup H, Bukh J, Gottwein JM.

Hepatology. 2019 Sep;70(3):771-787. doi: 10.1002/hep.30647. Epub 2019 Jun 5.

7.

Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL.

Xu-Monette ZY, Xiao M, Au Q, Padmanabhan R, Xu B, Hoe N, Rodríguez-Perales S, Torres-Ruiz R, Manyam GC, Visco C, Miao Y, Tan X, Zhang H, Tzankov A, Wang J, Dybkær K, Tam W, You H, Bhagat G, Hsi ED, Ponzoni M, Ferreri AJM, Møller MB, Piris MA, van Krieken JH, Winter JN, Westin JR, Pham LV, Medeiros LJ, Rassidakis GZ, Li Y, Freeman GJ, Young KH.

Cancer Immunol Res. 2019 Apr;7(4):644-657. doi: 10.1158/2326-6066.CIR-18-0439. Epub 2019 Feb 11.

PMID:
30745366
8.

Antimicrobial activity of rhodomyrtone isolated from Rhodomyrtus tomentosa (Aiton) Hassk.

Bach QN, Hongthong S, Quach LT, Pham LV, Pham TV, Kuhakarn C, Reutrakul V, Nguyen PTM.

Nat Prod Res. 2019 Jan 2:1-6. doi: 10.1080/14786419.2018.1540479. [Epub ahead of print]

PMID:
30600706
9.

A Novel Non-invasive Approach for Measuring Upper Airway Collapsibility in Mice.

Nishimura Y, Arias RS, Pho H, Pham LV, Curado TF, Polotsky VY, Schwartz AR.

Front Neurol. 2018 Nov 20;9:985. doi: 10.3389/fneur.2018.00985. eCollection 2018.

10.

Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma.

Mohanty A, Sandoval N, Phan A, Nguyen TV, Chen RW, Budde E, Mei M, Popplewell L, Pham LV, Kwak LW, Weisenburger DD, Rosen ST, Chan WC, Müschen M, Ngo VN.

Blood. 2019 Jan 24;133(4):306-318. doi: 10.1182/blood-2018-05-851667. Epub 2018 Dec 10.

PMID:
30530749
11.

HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.

Pham LV, Jensen SB, Fahnøe U, Pedersen MS, Tang Q, Ghanem L, Ramirez S, Humes D, Serre SBN, Schønning K, Bukh J, Gottwein JM.

J Hepatol. 2019 Mar;70(3):388-397. doi: 10.1016/j.jhep.2018.10.031. Epub 2018 Nov 3.

PMID:
30395912
12.

PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas.

Ren Y, Bi C, Zhao X, Lwin T, Wang C, Yuan J, Silva AS, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham LV, Sudalagunta PR, Wan L, Wang X, Dalton WS, Moscinski LC, Shain KH, Vose J, Cleveland JL, Sotomayor EM, Fu K, Tao J.

J Clin Invest. 2018 Dec 3;128(12):5517-5530. doi: 10.1172/JCI122533. Epub 2018 Nov 5.

13.

B-cell receptor-mediated NFATc1 activation induces IL-10/STAT3/PD-L1 signaling in diffuse large B-cell lymphoma.

Li L, Zhang J, Chen J, Xu-Monette ZY, Miao Y, Xiao M, Young KH, Wang S, Medeiros LJ, Wang M, Ford RJ, Pham LV.

Blood. 2018 Oct 25;132(17):1805-1817. doi: 10.1182/blood-2018-03-841015. Epub 2018 Sep 12.

14.

Unequal misses during the flash-induced advancement of photosystem II: effects of the S state and acceptor side cycles.

Pham LV, Janna Olmos JD, Chernev P, Kargul J, Messinger J.

Photosynth Res. 2019 Mar;139(1-3):93-106. doi: 10.1007/s11120-018-0574-0. Epub 2018 Sep 6.

15.

Oxyhemoglobin Saturation Overshoot Following Obstructive Breathing Events Mitigates Sleep Apnea-Induced Glucose Elevations.

Pham LV, Schwartz AR, Jun JC.

Front Endocrinol (Lausanne). 2018 Aug 23;9:477. doi: 10.3389/fendo.2018.00477. eCollection 2018.

16.

Integrating loop gain into the understanding of obstructive sleep apnoea mechanisms.

Pham LV, Schwartz AR, Polotsky VY.

J Physiol. 2018 Sep;596(17):3819-3820. doi: 10.1113/JP276590. Epub 2018 Jul 23. No abstract available.

17.

The Role of Macrophage/B-Cell Interactions in the Pathophysiology of B-Cell Lymphomas.

Pham LV, Pogue E, Ford RJ.

Front Oncol. 2018 May 8;8:147. doi: 10.3389/fonc.2018.00147. eCollection 2018. Review.

18.

Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas.

Pham LV, Huang S, Zhang H, Zhang J, Bell T, Zhou S, Pogue E, Ding Z, Lam L, Westin J, Davis RE, Young KH, Medeiros LJ, Ford RJ, Nomie K, Zhang L, Wang M.

Clin Cancer Res. 2018 Aug 15;24(16):3967-3980. doi: 10.1158/1078-0432.CCR-17-3004. Epub 2018 Apr 17.

19.

HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models.

Pham LV, Ramirez S, Gottwein JM, Fahnøe U, Li YP, Pedersen J, Bukh J.

Gastroenterology. 2018 Jun;154(8):2194-2208.e12. doi: 10.1053/j.gastro.2018.02.017. Epub 2018 Feb 15.

PMID:
29454794
20.

Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma.

Liu W, Chen J, Tamayo AT, Ruan C, Li L, Zhou S, Shen C, Young KH, Westin J, Davis RE, Hu S, Medeiros LJ, Ford RJ, Pham LV.

Oncotarget. 2017 Aug 21;9(1):346-360. doi: 10.18632/oncotarget.20378. eCollection 2018 Jan 2.

21.

Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1-7 and Escape Variants.

Gottwein JM, Pham LV, Mikkelsen LS, Ghanem L, Ramirez S, Scheel TKH, Carlsen THR, Bukh J.

Gastroenterology. 2018 Apr;154(5):1435-1448. doi: 10.1053/j.gastro.2017.12.015. Epub 2017 Dec 22.

PMID:
29274866
22.

Rad51 Interacts with Non-structural 3 Protein of Hepatitis C Virus and Regulates Viral Production.

Son K, Nguyen TTT, Choi JW, Pham LV, Luong TTD, Lim YS, Hwang SB.

Front Microbiol. 2017 Jul 6;8:1249. doi: 10.3389/fmicb.2017.01249. eCollection 2017.

23.

AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma.

Wang J, Xu-Monette ZY, Jabbar KJ, Shen Q, Manyam GC, Tzankov A, Visco C, Wang J, Montes-Moreno S, Dybkær K, Tam W, Bhagat G, Hsi ED, van Krieken JH, Ponzoni M, Ferreri AJM, Wang S, Møller MB, Piris MA, Medeiros LJ, Li Y, Pham LV, Young KH.

Am J Pathol. 2017 Aug;187(8):1700-1716. doi: 10.1016/j.ajpath.2017.04.009. Epub 2017 Jun 13.

24.

Cardiometabolic correlates of sleep disordered breathing in Andean highlanders.

Pham LV, Miele CH, Schwartz NG, Arias RS, Rattner A, Gilman RH, Miranda JJ, Polotsky VY, Checkley W, Schwartz AR.

Eur Respir J. 2017 Jun 15;49(6). pii: 1601705. doi: 10.1183/13993003.01705-2016. Print 2017 Jun.

25.

Obstructive Sleep Apnea Dynamically Increases Nocturnal Plasma Free Fatty Acids, Glucose, and Cortisol During Sleep.

Chopra S, Rathore A, Younas H, Pham LV, Gu C, Beselman A, Kim IY, Wolfe RR, Perin J, Polotsky VY, Jun JC.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3172-3181. doi: 10.1210/jc.2017-00619.

26.

Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors.

Pham LV, Ramirez S, Carlsen THR, Li YP, Gottwein JM, Bukh J.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00037-17. doi: 10.1128/AAC.00037-17. Print 2017 Jun.

27.

Cross-Sectional Comparison of Sleep-Disordered Breathing in Native Peruvian Highlanders and Lowlanders.

Pham LV, Meinzen C, Arias RS, Schwartz NG, Rattner A, Miele CH, Smith PL, Schneider H, Miranda JJ, Gilman RH, Polotsky VY, Checkley W, Schwartz AR.

High Alt Med Biol. 2017 Mar;18(1):11-19. doi: 10.1089/ham.2016.0102.

28.

Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency.

Fleury Curado T, Fishbein K, Pho H, Brennick M, Dergacheva O, Sennes LU, Pham LV, Ladenheim EE, Spencer R, Mendelowitz D, Schwartz AR, Polotsky VY.

Sci Rep. 2017 Mar 10;7:44392. doi: 10.1038/srep44392.

29.

RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma.

Zhang M, Xu-Monette ZY, Li L, Manyam GC, Visco C, Tzankov A, Wang J, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, Han van Krieken J, Huh J, Ponzoni M, Ferreri AJ, Møller MB, Parsons BM, Winter JN, Piris MA, Medeiros LJ, Pham LV, Young KH.

Aging (Albany NY). 2016 Dec 8;8(12):3321-3340. doi: 10.18632/aging.101121.

30.

Mantle Cell Lymphoma With MYC Rearrangement: A Report of 17 Patients.

Hu Z, Medeiros LJ, Chen Z, Chen W, Li S, Konoplev SN, Lu X, Pham LV, Young KH, Wang W, Hu S.

Am J Surg Pathol. 2017 Feb;41(2):216-224. doi: 10.1097/PAS.0000000000000758. Erratum in: Am J Surg Pathol. 2017 May;41(5):723.

PMID:
27776009
31.

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma.

Pham LV, Bryant JL, Mendez R, Chen J, Tamayo AT, Xu-Monette ZY, Young KH, Manyam GC, Yang D, Medeiros LJ, Ford RJ.

Oncotarget. 2016 Dec 6;7(49):80599-80611. doi: 10.18632/oncotarget.12413.

32.

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma.

Mohanty A, Sandoval N, Das M, Pillai R, Chen L, Chen RW, Amin HM, Wang M, Marcucci G, Weisenburger DD, Rosen ST, Pham LV, Ngo VN.

Oncotarget. 2016 Nov 8;7(45):73558-73572. doi: 10.18632/oncotarget.12434.

33.

Genome-Wide Association Studies in Obstructive Sleep Apnea. Will We Catch a Black Cat in a Dark Room?

Pham LV, Polotsky VY.

Am J Respir Crit Care Med. 2016 Oct 1;194(7):789-791. No abstract available.

34.

Probing S-state advancements and recombination pathways in photosystem II with a global fit program for flash-induced oxygen evolution pattern.

Pham LV, Messinger J.

Biochim Biophys Acta. 2016 Jun;1857(6):848-59. doi: 10.1016/j.bbabio.2016.03.013. Epub 2016 Mar 29.

35.

Establishment and characterization of a novel MYC/BCL2 "double-hit" diffuse large B cell lymphoma cell line, RC.

Pham LV, Lu G, Tamayo AT, Chen J, Challagundla P, Jorgensen JL, Medeiros LJ, Ford RJ.

J Hematol Oncol. 2015 Oct 29;8:121. doi: 10.1186/s13045-015-0218-1.

36.

The pathogenesis of obstructive sleep apnea.

Pham LV, Schwartz AR.

J Thorac Dis. 2015 Aug;7(8):1358-72. doi: 10.3978/j.issn.2072-1439.2015.07.28. Review.

37.

Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma.

Li L, Xu-Monette ZY, Ok CY, Tzankov A, Manyam GC, Sun R, Visco C, Zhang M, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Møller MB, Wang J, Parsons BM, Winter JN, Piris MA, Pham LV, Medeiros LJ, Young KH.

Oncotarget. 2015 Sep 15;6(27):23157-80.

38.

Stearoyl coenzyme A desaturase 1 is associated with hepatitis C virus replication complex and regulates viral replication.

Nguyen LN, Lim YS, Pham LV, Shin HY, Kim YS, Hwang SB.

J Virol. 2014 Nov;88(21):12311-25. doi: 10.1128/JVI.01678-14. Epub 2014 Aug 13.

39.

Involvement of tumor-associated macrophage activation in vitro during development of a novel mantle cell lymphoma cell line, PF-1, derived from a typical patient with relapsed disease.

Pham LV, Vang MT, Tamayo AT, Lu G, Challagundla P, Jorgensen JL, Rollo AA, Ou Z, Zhang L, Wang M, Ford RJ.

Leuk Lymphoma. 2015 Jan;56(1):186-93. doi: 10.3109/10428194.2014.901511. Epub 2014 Apr 29.

40.

Electrochemically produced hydrogen peroxide affects Joliot-type oxygen-evolution measurements of photosystem II.

Pham LV, Messinger J.

Biochim Biophys Acta. 2014 Sep;1837(9):1411-6. doi: 10.1016/j.bbabio.2014.01.013. Epub 2014 Jan 29.

41.

In vitro and in vivo therapeutic efficacy of carfilzomib in mantle cell lymphoma: targeting the immunoproteasome.

Zhang L, Pham LV, Newberry KJ, Ou Z, Liang R, Qian J, Sun L, Blonska M, You Y, Yang J, Lin X, Rollo A, Tamayo AT, Lee J, Ford RJ, Zhao X, Kwak LW, Yi Q, Wang M.

Mol Cancer Ther. 2013 Nov;12(11):2494-504. doi: 10.1158/1535-7163.MCT-13-0156. Epub 2013 Aug 29.

42.

Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma.

Axelrod M, Ou Z, Brett LK, Zhang L, Lopez ER, Tamayo AT, Gordon V, Ford RJ, Williams ME, Pham LV, Weber MJ, Wang ML.

Leukemia. 2014 Feb;28(2):407-10. doi: 10.1038/leu.2013.249. Epub 2013 Aug 27. No abstract available.

43.

Modulation of mitogen-activated protein kinase-activated protein kinase 3 by hepatitis C virus core protein.

Ngo HT, Pham LV, Kim JW, Lim YS, Hwang SB.

J Virol. 2013 May;87(10):5718-31. doi: 10.1128/JVI.03353-12. Epub 2013 Mar 13.

44.

Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma.

Zhang K, Wang M, Tamayo AT, Shacham S, Kauffman M, Lee J, Zhang L, Ou Z, Li C, Sun L, Ford RJ, Pham LV.

Exp Hematol. 2013 Jan;41(1):67-78.e4. doi: 10.1016/j.exphem.2012.09.002. Epub 2012 Sep 14.

PMID:
22986101
45.

Hepatitis C virus non-structural 5B protein interacts with cyclin A2 and regulates viral propagation.

Pham LV, Ngo HT, Lim YS, Hwang SB.

J Hepatol. 2012 Nov;57(5):960-6. doi: 10.1016/j.jhep.2012.07.006. Epub 2012 Jul 14.

PMID:
22796893
46.

The therapeutic effects of rGel/BLyS fusion toxin in in vitro and in vivo models of mantle cell lymphoma.

Lyu MA, Pham LV, Sung B, Tamayo AT, Ahn KS, Hittelman WN, Cheung LH, Marks JW, Cho MJ, Ford RJ, Aggarwal BB, Rosenblum MG.

Biochem Pharmacol. 2012 Aug 15;84(4):451-8. doi: 10.1016/j.bcp.2012.05.019. Epub 2012 Jun 9.

PMID:
22687624
47.

Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma.

Li C, Thompson MA, Tamayo AT, Zuo Z, Lee J, Vega F, Ford RJ, Pham LV.

Oncotarget. 2012 Mar;3(3):314-26.

48.

The role of BAFF-R dysregulation in B-lymphoid lineage malignancies.

Pham LV, Ford RJ.

Cell Cycle. 2011 Jan 15;10(2):189-90. Epub 2011 Jan 15. No abstract available.

PMID:
21239884
49.

Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways.

Pham LV, Fu L, Tamayo AT, Bueso-Ramos C, Drakos E, Vega F, Medeiros LJ, Ford RJ.

Blood. 2011 Jan 6;117(1):200-10. doi: 10.1182/blood-2010-06-290437. Epub 2010 Oct 1.

50.

An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas.

Pham LV, Tamayo AT, Li C, Bueso-Ramos C, Ford RJ.

Blood. 2010 Nov 11;116(19):3899-906. doi: 10.1182/blood-2009-12-257378. Epub 2010 Jul 27.

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