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Items: 17

1.

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.

Phadwal K, Kurian D, Salamat MKF, MacRae VE, Diack AB, Manson JC.

Sci Rep. 2018 Jul 3;8(1):10004. doi: 10.1038/s41598-018-28296-y.

2.

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

Liao C, Ashley N, Diot A, Morten K, Phadwal K, Williams A, Fearnley I, Rosser L, Lowndes J, Fratter C, Ferguson DJ, Vay L, Quaghebeur G, Moroni I, Bianchi S, Lamperti C, Downes SM, Sitarz KS, Flannery PJ, Carver J, Dombi E, East D, Laura M, Reilly MM, Mortiboys H, Prevo R, Campanella M, Daniels MJ, Zeviani M, Yu-Wai-Man P, Simon AK, Votruba M, Poulton J.

Neurology. 2017 Jan 10;88(2):131-142. doi: 10.1212/WNL.0000000000003491. Epub 2016 Dec 14.

3.

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

Watson AS, Riffelmacher T, Stranks A, Williams O, De Boer J, Cain K, MacFarlane M, McGouran J, Kessler B, Khandwala S, Chowdhury O, Puleston D, Phadwal K, Mortensen M, Ferguson D, Soilleux E, Woll P, Jacobsen SE, Simon AK.

Cell Death Discov. 2015 Aug 17;1. pii: 15008.

4.

Techniques for the Detection of Autophagy in Primary Mammalian Cells.

Puleston D, Phadwal K, Watson AS, Soilleux EJ, Chittaranjan S, Bortnik S, Gorski SM, Ktistakis N, Simon AK.

Cold Spring Harb Protoc. 2015 Sep 1;2015(9):pdb.top070391. doi: 10.1101/pdb.top070391.

PMID:
26330629
5.

Analyzing the Colocalization of MAP1LC3 and Lysosomal Markers in Primary Cells.

Phadwal K.

Cold Spring Harb Protoc. 2015 Sep 1;2015(9):pdb.prot086272. doi: 10.1101/pdb.prot086272.

PMID:
26330623
6.

Autophagy Controls Acquisition of Aging Features in Macrophages.

Stranks AJ, Hansen AL, Panse I, Mortensen M, Ferguson DJ, Puleston DJ, Shenderov K, Watson AS, Veldhoen M, Phadwal K, Cerundolo V, Simon AK.

J Innate Immun. 2015;7(4):375-91. doi: 10.1159/000370112. Epub 2015 Mar 10.

7.

ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia.

Pike LR, Phadwal K, Simon AK, Harris AL.

Mol Biol Rep. 2012 Dec;39(12):10811-22. doi: 10.1007/s11033-012-1975-3. Epub 2012 Oct 23.

PMID:
23090478
8.

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.

Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, Simon AK, Murray JT, Harris AL.

Biochem J. 2013 Jan 15;449(2):389-400. doi: 10.1042/BJ20120972.

PMID:
23078367
9.

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging.

Phadwal K, Watson AS, Simon AK.

Cell Mol Life Sci. 2013 Jan;70(1):89-103. doi: 10.1007/s00018-012-1032-3. Epub 2012 Jun 5. Review.

10.

Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.

Lopez-Herrera G, Tampella G, Pan-Hammarström Q, Herholz P, Trujillo-Vargas CM, Phadwal K, Simon AK, Moutschen M, Etzioni A, Mory A, Srugo I, Melamed D, Hultenby K, Liu C, Baronio M, Vitali M, Philippet P, Dideberg V, Aghamohammadi A, Rezaei N, Enright V, Du L, Salzer U, Eibel H, Pfeifer D, Veelken H, Stauss H, Lougaris V, Plebani A, Gertz EM, Schäffer AA, Hammarström L, Grimbacher B.

Am J Hum Genet. 2012 Jun 8;90(6):986-1001. doi: 10.1016/j.ajhg.2012.04.015. Epub 2012 May 17.

11.

A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.

Phadwal K, Alegre-Abarrategui J, Watson AS, Pike L, Anbalagan S, Hammond EM, Wade-Martins R, McMichael A, Klenerman P, Simon AK.

Autophagy. 2012 Apr;8(4):677-89. doi: 10.4161/auto.18935. Epub 2012 Apr 1.

12.

HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes.

Kwok AS, Phadwal K, Turner BJ, Oliver PL, Raw A, Simon AK, Talbot K, Agashe VR.

J Neurochem. 2011 Dec;119(6):1155-61. doi: 10.1111/j.1471-4159.2011.07521.x. Epub 2011 Nov 3.

13.

T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challenges.

Flower DR, Phadwal K, Macdonald IK, Coveney PV, Davies MN, Wan S.

Immunome Res. 2010 Nov 3;6 Suppl 2:S4. doi: 10.1186/1745-7580-6-S2-S4.

14.

Proteomic characterization of acid stress response in Synechocystis sp. PCC 6803.

Kurian D, Phadwal K, Mäenpää P.

Proteomics. 2006 Jun;6(12):3614-24.

PMID:
16691555
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