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Items: 1 to 50 of 313

1.

MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.

Wild K, Aleksić M, Lapouge K, Juaire KD, Flemming D, Pfeffer S, Sinning I.

Nat Commun. 2020 Feb 7;11(1):776. doi: 10.1038/s41467-020-14603-7.

2.

TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channel.

Klein MC, Lerner M, Nguyen D, Pfeffer S, Dudek J, Förster F, Helms V, Lang S, Zimmermann R.

Channels (Austin). 2020 Dec;14(1):28-44. doi: 10.1080/19336950.2020.1724759.

PMID:
32013668
3.

Author Correction: Template-free detection and classification of membrane-bound complexes in cryo-electron tomograms.

Martinez-Sanchez A, Kochovski Z, Laugks U, Meyer Zum Alten Borgloh J, Chakraborty S, Pfeffer S, Baumeister W, Lučić V.

Nat Methods. 2020 Feb;17(2):240. doi: 10.1038/s41592-020-0763-6.

PMID:
31988520
4.

Author Correction: Template-free detection and classification of membrane-bound complexes in cryo-electron tomograms.

Martinez-Sanchez A, Kochovski Z, Laugks U, Meyer Zum Alten Borgloh J, Chakraborty S, Pfeffer S, Baumeister W, Lučić V.

Nat Methods. 2020 Feb;17(2):240. doi: 10.1038/s41592-020-0747-6.

PMID:
31969729
5.

Functions and Mechanisms of the Human Ribosome-Translocon Complex.

Lang S, Nguyen D, Pfeffer S, Förster F, Helms V, Zimmermann R.

Subcell Biochem. 2019;93:83-141. doi: 10.1007/978-3-030-28151-9_4. Review.

PMID:
31939150
6.

Template-free detection and classification of membrane-bound complexes in cryo-electron tomograms.

Martinez-Sanchez A, Kochovski Z, Laugks U, Meyer Zum Alten Borgloh J, Chakraborty S, Pfeffer S, Baumeister W, Lučić V.

Nat Methods. 2020 Feb;17(2):209-216. doi: 10.1038/s41592-019-0675-5. Epub 2020 Jan 6. Erratum in: Nat Methods. 2020 Jan 22;:. Nat Methods. 2020 Jan 27;:.

PMID:
31907446
7.

Insights into the assembly and activation of the microtubule nucleator γ-TuRC.

Liu P, Zupa E, Neuner A, Böhler A, Loerke J, Flemming D, Ruppert T, Rudack T, Peter C, Spahn C, Gruss OJ, Pfeffer S, Schiebel E.

Nature. 2020 Feb;578(7795):467-471. doi: 10.1038/s41586-019-1896-6. Epub 2019 Dec 19.

PMID:
31856152
8.

[ReSi: Evaluation of a Program for Competency Training and Prevention of Sexual Abuse in Kindergarten].

Feldmann J, Storck C, Pfeffer S.

Prax Kinderpsychol Kinderpsychiatr. 2018 Dec;67(8):720-735. doi: 10.13109/prkk.2018.67.8.720. German.

PMID:
31801427
9.

CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines.

Lentsch E, Li L, Pfeffer S, Ekici AB, Taher L, Pilarsky C, Grützmann R.

Int J Mol Sci. 2019 Nov 14;20(22). pii: E5706. doi: 10.3390/ijms20225706.

10.

HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway.

Spaety ME, Gries A, Badie A, Venkatasamy A, Romain B, Orvain C, Yanagihara K, Okamoto K, Jung AC, Mellitzer G, Pfeffer S, Gaiddon C.

Cancers (Basel). 2019 Nov 7;11(11). pii: E1747. doi: 10.3390/cancers11111747.

11.

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.

Berndsen K, Lis P, Yeshaw WM, Wawro PS, Nirujogi RS, Wightman M, Macartney T, Dorward M, Knebel A, Tonelli F, Pfeffer SR, Alessi DR.

Elife. 2019 Oct 30;8. pii: e50416. doi: 10.7554/eLife.50416.

12.

Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.

Gomez RC, Wawro P, Lis P, Alessi DR, Pfeffer SR.

J Cell Biol. 2019 Dec 2;218(12):4157-4170. doi: 10.1083/jcb.201902184. Epub 2019 Oct 17.

PMID:
31624137
13.

High-speed locomotion in the Saharan silver ant, Cataglyphis bombycina.

Pfeffer SE, Wahl VL, Wittlinger M, Wolf H.

J Exp Biol. 2019 Oct 16;222(Pt 20). pii: jeb198705. doi: 10.1242/jeb.198705.

PMID:
31619540
14.

[Importance of cellular microRNAs in the regulation of viral infections].

López P, Girardi E, Pfeffer S.

Med Sci (Paris). 2019 Aug-Sep;35(8-9):667-673. doi: 10.1051/medsci/2019130. Epub 2019 Sep 18. Review. French.

PMID:
31532379
15.

A cryo-FIB lift-out technique enables molecular-resolution cryo-ET within native Caenorhabditis elegans tissue.

Schaffer M, Pfeffer S, Mahamid J, Kleindiek S, Laugks T, Albert S, Engel BD, Rummel A, Smith AJ, Baumeister W, Plitzko JM.

Nat Methods. 2019 Aug;16(8):757-762. doi: 10.1038/s41592-019-0497-5. Epub 2019 Jul 29.

PMID:
31363205
16.

Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity.

Herzog K, Bandiera S, Pernot S, Fauvelle C, Jühling F, Weiss A, Bull A, Durand SC, Chane-Woon-Ming B, Pfeffer S, Mercey M, Lerat H, Meunier JC, Raffelsberger W, Brino L, Baumert TF, Zeisel MB.

Gut. 2020 Feb;69(2):380-392. doi: 10.1136/gutjnl-2018-317423. Epub 2019 May 10.

PMID:
31076402
17.

Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane.

Rast A, Schaffer M, Albert S, Wan W, Pfeffer S, Beck F, Plitzko JM, Nickelsen J, Engel BD.

Nat Plants. 2019 Apr;5(4):436-446. doi: 10.1038/s41477-019-0399-7. Epub 2019 Apr 8.

PMID:
30962530
18.

Treatment of Chemotherapy-Induced Thrombotic Microangiopathy with Eculizumab in a Patient with Metastatic Breast Cancer.

Hausberg M, Felten H, Pfeffer S.

Case Rep Oncol. 2019 Jan 3;12(1):1-6. doi: 10.1159/000495031. eCollection 2019 Jan-Apr.

19.

NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes.

Pfeffer SR.

J Biol Chem. 2019 Feb 1;294(5):1706-1709. doi: 10.1074/jbc.TM118.004165. Review.

20.

Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR.

EMBO J. 2019 Jan 15;38(2). pii: e101237. doi: 10.15252/embj.2018101237. No abstract available.

21.

Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs.

Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR.

Elife. 2018 Dec 17;7. pii: e41460. doi: 10.7554/eLife.41460.

22.

LRRK2 and Rab GTPases.

Pfeffer SR.

Biochem Soc Trans. 2018 Dec 17;46(6):1707-1712. doi: 10.1042/BST20180470. Epub 2018 Nov 22. Review.

PMID:
30467121
23.

A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.

Dhekne HS, Yanatori I, Gomez RC, Tonelli F, Diez F, Schüle B, Steger M, Alessi DR, Pfeffer SR.

Elife. 2018 Nov 6;7. pii: e40202. doi: 10.7554/eLife.40202.

24.

Unravelling molecular complexity in structural cell biology.

Pfeffer S, Mahamid J.

Curr Opin Struct Biol. 2018 Oct;52:111-118. doi: 10.1016/j.sbi.2018.08.009. Epub 2018 Oct 16. Review.

PMID:
30339965
25.

On the Importance of Host MicroRNAs During Viral Infection.

Girardi E, López P, Pfeffer S.

Front Genet. 2018 Oct 2;9:439. doi: 10.3389/fgene.2018.00439. eCollection 2018. Review.

26.

Two distance memories in desert ants-Modes of interaction.

Wolf H, Wittlinger M, Pfeffer SE.

PLoS One. 2018 Oct 10;13(10):e0204664. doi: 10.1371/journal.pone.0204664. eCollection 2018.

27.

Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import.

Nguyen D, Stutz R, Schorr S, Lang S, Pfeffer S, Freeze HH, Förster F, Helms V, Dudek J, Zimmermann R.

Nat Commun. 2018 Sep 14;9(1):3765. doi: 10.1038/s41467-018-06188-z.

28.

Response to letter to the editor: "Comments on Unambiguous identification and characterization of a long-term human metabolite of dehydrochloromethyltestosterone".

Forsdahl G, Geisendorfer T, Göschl L, Pfeffer S, Gärtner P, Thevis M, Gmeiner G.

Drug Test Anal. 2019 Jan;11(1):185. doi: 10.1002/dta.2486. Epub 2018 Sep 9. No abstract available.

PMID:
30133177
29.

mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding.

Delarue M, Brittingham GP, Pfeffer S, Surovtsev IV, Pinglay S, Kennedy KJ, Schaffer M, Gutierrez JI, Sang D, Poterewicz G, Chung JK, Plitzko JM, Groves JT, Jacobs-Wagner C, Engel BD, Holt LJ.

Cell. 2018 Jul 12;174(2):338-349.e20. doi: 10.1016/j.cell.2018.05.042. Epub 2018 Jun 21.

30.

Regulation of primary microRNA processing.

Creugny A, Fender A, Pfeffer S.

FEBS Lett. 2018 Jun;592(12):1980-1996. doi: 10.1002/1873-3468.13067. Epub 2018 May 8. Review.

31.

Unambiguous identification and characterization of a long-term human metabolite of dehydrochloromethyltestosterone.

Forsdahl G, Geisendorfer T, Göschl L, Pfeffer S, Gärtner P, Thevis M, Gmeiner G.

Drug Test Anal. 2018 Mar 23. doi: 10.1002/dta.2385. [Epub ahead of print]

PMID:
29570240
32.

Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.

Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Förster F, Beckmann R.

Science. 2018 Apr 13;360(6385):215-219. doi: 10.1126/science.aar7899. Epub 2018 Mar 8.

33.

Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR.

EMBO J. 2018 Jan 4;37(1):1-18. doi: 10.15252/embj.201798099. Epub 2017 Dec 6. Erratum in: EMBO J. 2019 Jan 15;38(2):.

34.

An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.

Lang S, Pfeffer S, Lee PH, Cavalié A, Helms V, Förster F, Zimmermann R.

Front Physiol. 2017 Nov 1;8:887. doi: 10.3389/fphys.2017.00887. eCollection 2017. Review.

35.

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M.

Elife. 2017 Nov 10;6. pii: e31012. doi: 10.7554/eLife.31012.

36.

Structure of the Human Mitochondrial Ribosome Studied In Situ by Cryoelectron Tomography.

Englmeier R, Pfeffer S, Förster F.

Structure. 2017 Oct 3;25(10):1574-1581.e2. doi: 10.1016/j.str.2017.07.011. Epub 2017 Aug 31.

37.

Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1).

Schubert D, Klein MC, Hassdenteufel S, Caballero-Oteyza A, Yang L, Proietti M, Bulashevska A, Kemming J, Kühn J, Winzer S, Rusch S, Fliegauf M, Schäffer AA, Pfeffer S, Geiger R, Cavalié A, Cao H, Yang F, Li Y, Rizzi M, Eibel H, Kobbe R, Marks AL, Peppers BP, Hostoffer RW, Puck JM, Zimmermann R, Grimbacher B.

J Allergy Clin Immunol. 2018 Apr;141(4):1427-1438. doi: 10.1016/j.jaci.2017.06.042. Epub 2017 Aug 4.

38.

Unphosphorylated STAT3 regulates the antiproliferative, antiviral, and gene-inducing actions of type I interferons.

Pfeffer SR, Fan M, Du Z, Yang CH, Pfeffer LM.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):739-745. doi: 10.1016/j.bbrc.2017.06.111. Epub 2017 Jun 20.

39.

Complete Genome Sequence of Komagataeibacter hansenii Strain SC-3B.

Pfeffer S, Santos R, Ebels M, Bordbar D, Brown RM Jr.

Genome Announc. 2017 Apr 13;5(15). pii: e00169-17. doi: 10.1128/genomeA.00169-17.

40.

Complete Genome Sequence of Komagataeibacter hansenii LMG 23726T.

Pfeffer S, Santos R, Ebels M, Bordbar D, Brown RM Jr.

Genome Announc. 2017 Apr 13;5(15). pii: e00168-17. doi: 10.1128/genomeA.00168-17.

41.

Complete Genome Sequence of Komagataeibacter hansenii Strain HUM-1.

Pfeffer S, Santos R, Ebels M, Bordbar D, Brown RM Jr.

Genome Announc. 2017 Apr 13;5(15). pii: e00167-17. doi: 10.1128/genomeA.00167-17.

42.

Rab GTPases: master regulators that establish the secretory and endocytic pathways.

Pfeffer SR.

Mol Biol Cell. 2017 Mar 15;28(6):712-715. doi: 10.1091/mbc.E16-10-0737. Review.

43.

Dissecting the molecular organization of the translocon-associated protein complex.

Pfeffer S, Dudek J, Schaffer M, Ng BG, Albert S, Plitzko JM, Baumeister W, Zimmermann R, Freeze HH, Engel BD, Förster F.

Nat Commun. 2017 Feb 20;8:14516. doi: 10.1038/ncomms14516.

44.

Quantitative Measurement of Cholesterol in Cell Populations Using Flow Cytometry and Fluorescent Perfringolysin O.

Li J, Lee PL, Pfeffer SR.

Methods Mol Biol. 2017;1583:85-95. doi: 10.1007/978-1-4939-6875-6_8.

PMID:
28205169
45.

Naturalistic path integration of Cataglyphis desert ants on an air-cushioned lightweight spherical treadmill.

Dahmen H, Wahl VL, Pfeffer SE, Mallot HA, Wittlinger M.

J Exp Biol. 2017 Feb 15;220(Pt 4):634-644. doi: 10.1242/jeb.148213.

46.

Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export.

Li J, Pfeffer SR.

Elife. 2016 Sep 24;5. pii: e21635. doi: 10.7554/eLife.21635.

47.

MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis.

Yang CH, Wang Y, Sims M, Cai C, He P, Yue J, Cheng J, Boop FA, Pfeffer SR, Pfeffer LM.

Oncotarget. 2016 Dec 20;7(51):84017-84029. doi: 10.18632/oncotarget.12401.

48.

Optic flow odometry operates independently of stride integration in carried ants.

Pfeffer SE, Wittlinger M.

Science. 2016 Sep 9;353(6304):1155-7. doi: 10.1126/science.aaf9754.

49.

Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2.

Li X, Saha P, Li J, Blobel G, Pfeffer SR.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10079-84. doi: 10.1073/pnas.1611956113. Epub 2016 Aug 22.

50.

Complete Genome Sequence of a Novel Strain of Cyanobacterium, Anabaena sp. 4-3.

Pfeffer S, Sowa S, Brown RM Jr.

Genome Announc. 2016 Aug 18;4(4). pii: e00842-16. doi: 10.1128/genomeA.00842-16.

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