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Items: 7


Bridging barriers: a comparative look at the blood-brain barrier across organisms.

O'Brown NM, Pfau SJ, Gu C.

Genes Dev. 2018 Apr 1;32(7-8):466-478. doi: 10.1101/gad.309823.117. Review.


Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.

Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik A, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A.

Cancer Res. 2017 Oct 1;77(19):5272-5286. doi: 10.1158/0008-5472.CAN-17-0049. Epub 2017 Aug 3.


Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo.

Pfau SJ, Silberman RE, Knouse KA, Amon A.

Genes Dev. 2016 Jun 15;30(12):1395-408. doi: 10.1101/gad.278820.116. Epub 2016 Jun 16.


A System to Study Aneuploidy In Vivo.

Pfau SJ, Amon A.

Cold Spring Harb Symp Quant Biol. 2015;80:93-101. doi: 10.1101/sqb.2015.80.027193. Epub 2016 Mar 2. Review.


Chromosomal instability and aneuploidy in cancer: from yeast to man.

Pfau SJ, Amon A.

EMBO Rep. 2012 Jun 1;13(6):515-27. doi: 10.1038/embor.2012.65. Review.


Aneuploidy drives genomic instability in yeast.

Sheltzer JM, Blank HM, Pfau SJ, Tange Y, George BM, Humpton TJ, Brito IL, Hiraoka Y, Niwa O, Amon A.

Science. 2011 Aug 19;333(6045):1026-30. doi: 10.1126/science.1206412.


let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts.

Legesse-Miller A, Elemento O, Pfau SJ, Forman JJ, Tavazoie S, Coller HA.

J Biol Chem. 2009 Mar 13;284(11):6605-9. doi: 10.1074/jbc.C900002200. Epub 2009 Jan 6.

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