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Items: 1 to 50 of 282

1.

Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26-Mic27 Antagonism and Cardiolipin.

Rampelt H, Wollweber F, Gerke C, de Boer R, van der Klei IJ, Bohnert M, Pfanner N, van der Laan M.

J Mol Biol. 2018 Jun 22;430(13):1883-1890. doi: 10.1016/j.jmb.2018.04.037. Epub 2018 May 4.

PMID:
29733859
2.

Assembling the mitochondrial ATP synthase.

Song J, Pfanner N, Becker T.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):2850-2852. doi: 10.1073/pnas.1801697115. Epub 2018 Mar 7. No abstract available.

PMID:
29514954
3.

Membrane protein insertion through a mitochondrial β-barrel gate.

Höhr AIC, Lindau C, Wirth C, Qiu J, Stroud DA, Kutik S, Guiard B, Hunte C, Becker T, Pfanner N, Wiedemann N.

Science. 2018 Jan 19;359(6373). pii: eaah6834. doi: 10.1126/science.aah6834.

PMID:
29348211
4.

Identification of new channels by systematic analysis of the mitochondrial outer membrane.

Krüger V, Becker T, Becker L, Montilla-Martinez M, Ellenrieder L, Vögtle FN, Meyer HE, Ryan MT, Wiedemann N, Warscheid B, Pfanner N, Wagner R, Meisinger C.

J Cell Biol. 2017 Nov 6;216(11):3485-3495. doi: 10.1083/jcb.201706043. Epub 2017 Sep 15.

5.

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale.

Morgenstern M, Stiller SB, Lübbert P, Peikert CD, Dannenmaier S, Drepper F, Weill U, Höß P, Feuerstein R, Gebert M, Bohnert M, van der Laan M, Schuldiner M, Schütze C, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B.

Cell Rep. 2017 Jun 27;19(13):2836-2852. doi: 10.1016/j.celrep.2017.06.014.

6.

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.

Hessenberger M, Zerbes RM, Rampelt H, Kunz S, Xavier AH, Purfürst B, Lilie H, Pfanner N, van der Laan M, Daumke O.

Nat Commun. 2017 May 31;8:15258. doi: 10.1038/ncomms15258.

7.

Mic10, a Core Subunit of the Mitochondrial Contact Site and Cristae Organizing System, Interacts with the Dimeric F1Fo-ATP Synthase.

Rampelt H, Bohnert M, Zerbes RM, Horvath SE, Warscheid B, Pfanner N, van der Laan M.

J Mol Biol. 2017 Apr 21;429(8):1162-1170. doi: 10.1016/j.jmb.2017.03.006. Epub 2017 Mar 15.

PMID:
28315355
8.

Mitochondrial Machineries for Protein Import and Assembly.

Wiedemann N, Pfanner N.

Annu Rev Biochem. 2017 Jun 20;86:685-714. doi: 10.1146/annurev-biochem-060815-014352. Epub 2017 Mar 15. Review.

PMID:
28301740
9.

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.

Chatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, Böttinger L, Mårtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar A.

Cell. 2016 Oct 20;167(3):722-738.e23. doi: 10.1016/j.cell.2016.09.052.

10.

Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10.

Ellenrieder L, Opaliński Ł, Becker L, Krüger V, Mirus O, Straub SP, Ebell K, Flinner N, Stiller SB, Guiard B, Meisinger C, Wiedemann N, Schleiff E, Wagner R, Pfanner N, Becker T.

Nat Commun. 2016 Oct 10;7:13021. doi: 10.1038/ncomms13021.

11.

Coordination of Two Genomes by Mitochondrial Translational Plasticity.

Rampelt H, Pfanner N.

Cell. 2016 Oct 6;167(2):308-310. doi: 10.1016/j.cell.2016.09.042.

12.

Role of the mitochondrial contact site and cristae organizing system in membrane architecture and dynamics.

Rampelt H, Zerbes RM, van der Laan M, Pfanner N.

Biochim Biophys Acta. 2017 Apr;1864(4):737-746. doi: 10.1016/j.bbamcr.2016.05.020. Epub 2016 Sep 7. Review.

13.

Dynamic organization of the mitochondrial protein import machinery.

Straub SP, Stiller SB, Wiedemann N, Pfanner N.

Biol Chem. 2016 Nov 1;397(11):1097-1114. doi: 10.1515/hsz-2016-0145. Review.

PMID:
27289000
14.

Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins.

Stiller SB, Höpker J, Oeljeklaus S, Schütze C, Schrempp SG, Vent-Schmidt J, Horvath SE, Frazier AE, Gebert N, van der Laan M, Bohnert M, Warscheid B, Pfanner N, Wiedemann N.

Cell Metab. 2016 May 10;23(5):901-8. doi: 10.1016/j.cmet.2016.04.005.

15.

Mitochondrial contact site and cristae organizing system.

van der Laan M, Horvath SE, Pfanner N.

Curr Opin Cell Biol. 2016 Aug;41:33-42. doi: 10.1016/j.ceb.2016.03.013. Epub 2016 Apr 7. Review.

PMID:
27062547
16.

Distinct Roles of Mic12 and Mic27 in the Mitochondrial Contact Site and Cristae Organizing System.

Zerbes RM, Höß P, Pfanner N, van der Laan M, Bohnert M.

J Mol Biol. 2016 Apr 24;428(8):1485-92. doi: 10.1016/j.jmb.2016.02.031. Epub 2016 Mar 8.

PMID:
26968360
17.

Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

Wenz LS, Ellenrieder L, Qiu J, Bohnert M, Zufall N, van der Laan M, Pfanner N, Wiedemann N, Becker T.

J Cell Biol. 2015 Sep 28;210(7):1047-54. doi: 10.1083/jcb.201504119.

18.

Molecular architecture of the active mitochondrial protein gate.

Shiota T, Imai K, Qiu J, Hewitt VL, Tan K, Shen HH, Sakiyama N, Fukasawa Y, Hayat S, Kamiya M, Elofsson A, Tomii K, Horton P, Wiedemann N, Pfanner N, Lithgow T, Endo T.

Science. 2015 Sep 25;349(6255):1544-8. doi: 10.1126/science.aac6428.

PMID:
26404837
19.

Mitochondrial machineries for insertion of membrane proteins.

Bohnert M, Pfanner N, van der Laan M.

Curr Opin Struct Biol. 2015 Aug;33:92-102. doi: 10.1016/j.sbi.2015.07.013. Epub 2015 Aug 26. Review.

PMID:
26296231
20.

Central role of Mic10 in the mitochondrial contact site and cristae organizing system.

Bohnert M, Zerbes RM, Davies KM, Mühleip AW, Rampelt H, Horvath SE, Boenke T, Kram A, Perschil I, Veenhuis M, Kühlbrandt W, van der Klei IJ, Pfanner N, van der Laan M.

Cell Metab. 2015 May 5;21(5):747-55. doi: 10.1016/j.cmet.2015.04.007.

21.

Role of membrane contact sites in protein import into mitochondria.

Horvath SE, Rampelt H, Oeljeklaus S, Warscheid B, van der Laan M, Pfanner N.

Protein Sci. 2015 Mar;24(3):277-97. doi: 10.1002/pro.2625. Epub 2015 Feb 12. Review.

22.

Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane.

Ieva R, Schrempp SG, Opaliński L, Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M.

Mol Cell. 2014 Dec 4;56(5):641-52. doi: 10.1016/j.molcel.2014.10.010. Epub 2014 Nov 13.

23.

Mitochondria. Cell cycle-dependent regulation of mitochondrial preprotein translocase.

Harbauer AB, Opalińska M, Gerbeth C, Herman JS, Rao S, Schönfisch B, Guiard B, Schmidt O, Pfanner N, Meisinger C.

Science. 2014 Nov 28;346(6213):1109-13. doi: 10.1126/science.1261253. Epub 2014 Nov 6.

24.

Visualizing active membrane protein complexes by electron cryotomography.

Gold VA, Ieva R, Walter A, Pfanner N, van der Laan M, Kühlbrandt W.

Nat Commun. 2014 Jun 19;5:4129. doi: 10.1038/ncomms5129.

25.

Clearing tail-anchored proteins from mitochondria.

Opaliński Ł, Becker T, Pfanner N.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):7888-9. doi: 10.1073/pnas.1406864111. Epub 2014 May 22. No abstract available.

26.

The presequence pathway is involved in protein sorting to the mitochondrial outer membrane.

Wenz LS, Opaliński L, Schuler MH, Ellenrieder L, Ieva R, Böttinger L, Qiu J, van der Laan M, Wiedemann N, Guiard B, Pfanner N, Becker T.

EMBO Rep. 2014 Jun;15(6):678-85. doi: 10.1002/embr.201338144. Epub 2014 Apr 29.

27.

Uniform nomenclature for the mitochondrial contact site and cristae organizing system.

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J.

J Cell Biol. 2014 Mar 31;204(7):1083-6. doi: 10.1083/jcb.201401006.

28.

The protein import machinery of mitochondria-a regulatory hub in metabolism, stress, and disease.

Harbauer AB, Zahedi RP, Sickmann A, Pfanner N, Meisinger C.

Cell Metab. 2014 Mar 4;19(3):357-72. doi: 10.1016/j.cmet.2014.01.010. Epub 2014 Feb 20. Review.

29.

Mitochondrial inner membrane protease promotes assembly of presequence translocase by removing a carboxy-terminal targeting sequence.

Ieva R, Heißwolf AK, Gebert M, Vögtle FN, Wollweber F, Mehnert CS, Oeljeklaus S, Warscheid B, Meisinger C, van der Laan M, Pfanner N.

Nat Commun. 2013;4:2853. doi: 10.1038/ncomms3853.

PMID:
24287567
30.

Glucose-induced regulation of protein import receptor Tom22 by cytosolic and mitochondria-bound kinases.

Gerbeth C, Schmidt O, Rao S, Harbauer AB, Mikropoulou D, Opalińska M, Guiard B, Pfanner N, Meisinger C.

Cell Metab. 2013 Oct 1;18(4):578-87. doi: 10.1016/j.cmet.2013.09.006.

31.

Voltage-coupled conformational dynamics of mitochondrial protein-import channel.

van der Laan M, Schrempp SG, Pfanner N.

Nat Struct Mol Biol. 2013 Aug;20(8):915-7. doi: 10.1038/nsmb.2643. No abstract available.

PMID:
23912355
32.

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation.

Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T.

Cell. 2013 Aug 1;154(3):596-608. doi: 10.1016/j.cell.2013.06.033.

33.

Role of phosphatidylethanolamine in the biogenesis of mitochondrial outer membrane proteins.

Becker T, Horvath SE, Böttinger L, Gebert N, Daum G, Pfanner N.

J Biol Chem. 2013 Jun 7;288(23):16451-9. doi: 10.1074/jbc.M112.442392. Epub 2013 Apr 26.

34.

Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation.

Wiedemann N, Stiller SB, Pfanner N.

Mol Cell. 2013 Feb 7;49(3):423-5. doi: 10.1016/j.molcel.2013.01.027.

35.

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture.

Zerbes RM, van der Klei IJ, Veenhuis M, Pfanner N, van der Laan M, Bohnert M.

Biol Chem. 2012 Nov;393(11):1247-61. doi: 10.1515/hsz-2012-0239. Review.

PMID:
23109542
36.

Mechanisms of protein sorting in mitochondria.

Stojanovski D, Bohnert M, Pfanner N, van der Laan M.

Cold Spring Harb Perspect Biol. 2012 Oct 1;4(10). pii: a011320. doi: 10.1101/cshperspect.a011320. Review.

37.

Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes.

Böttinger L, Horvath SE, Kleinschroth T, Hunte C, Daum G, Pfanner N, Becker T.

J Mol Biol. 2012 Nov 9;423(5):677-86. doi: 10.1016/j.jmb.2012.09.001. Epub 2012 Sep 10.

38.

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane.

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M.

Mol Biol Cell. 2012 Oct;23(20):3948-56. doi: 10.1091/mbc.E12-04-0295. Epub 2012 Aug 23.

39.

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes.

Gebert M, Schrempp SG, Mehnert CS, Heißwolf AK, Oeljeklaus S, Ieva R, Bohnert M, von der Malsburg K, Wiese S, Kleinschroth T, Hunte C, Meyer HE, Haferkamp I, Guiard B, Warscheid B, Pfanner N, van der Laan M.

J Cell Biol. 2012 May 28;197(5):595-604. doi: 10.1083/jcb.201110047. Epub 2012 May 21.

40.

Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains.

Zerbes RM, Bohnert M, Stroud DA, von der Malsburg K, Kram A, Oeljeklaus S, Warscheid B, Becker T, Wiedemann N, Veenhuis M, van der Klei IJ, Pfanner N, van der Laan M.

J Mol Biol. 2012 Sep 14;422(2):183-91. doi: 10.1016/j.jmb.2012.05.004. Epub 2012 May 7.

41.

Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import.

Rao S, Schmidt O, Harbauer AB, Schönfisch B, Guiard B, Pfanner N, Meisinger C.

Mol Biol Cell. 2012 May;23(9):1618-27. doi: 10.1091/mbc.E11-11-0933. Epub 2012 Mar 14.

42.

Role of MINOS in mitochondrial membrane architecture and biogenesis.

van der Laan M, Bohnert M, Wiedemann N, Pfanner N.

Trends Cell Biol. 2012 Apr;22(4):185-92. doi: 10.1016/j.tcb.2012.01.004. Epub 2012 Mar 2.

PMID:
22386790
43.

Mitochondrial protein import: from transport pathways to an integrated network.

Becker T, Böttinger L, Pfanner N.

Trends Biochem Sci. 2012 Mar;37(3):85-91. doi: 10.1016/j.tibs.2011.11.004. Epub 2011 Dec 16.

PMID:
22178138
44.

Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.

Gebert N, Gebert M, Oeljeklaus S, von der Malsburg K, Stroud DA, Kulawiak B, Wirth C, Zahedi RP, Dolezal P, Wiese S, Simon O, Schulze-Specking A, Truscott KN, Sickmann A, Rehling P, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N.

Mol Cell. 2011 Dec 9;44(5):811-8. doi: 10.1016/j.molcel.2011.09.025.

45.

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.

von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M, Warscheid B, van der Klei IJ, Pfanner N, Chacinska A, van der Laan M.

Dev Cell. 2011 Oct 18;21(4):694-707. doi: 10.1016/j.devcel.2011.08.026. Epub 2011 Sep 22.

46.

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins.

Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N.

J Cell Biol. 2011 Aug 8;194(3):387-95. doi: 10.1083/jcb.201102044.

47.

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.

Qian X, Gebert M, Höpker J, Yan M, Li J, Wiedemann N, van der Laan M, Pfanner N, Sha B.

J Mol Biol. 2011 Aug 19;411(3):513-9. doi: 10.1016/j.jmb.2011.06.020. Epub 2011 Jun 17.

48.

Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex.

Stroud DA, Becker T, Qiu J, Stojanovski D, Pfannschmidt S, Wirth C, Hunte C, Guiard B, Meisinger C, Pfanner N, Wiedemann N.

Mol Biol Cell. 2011 Aug 15;22(16):2823-33. doi: 10.1091/mbc.E11-02-0148. Epub 2011 Jun 16.

49.

Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization.

Vögtle FN, Prinz C, Kellermann J, Lottspeich F, Pfanner N, Meisinger C.

Mol Biol Cell. 2011 Jul 1;22(13):2135-43. doi: 10.1091/mbc.E11-02-0169. Epub 2011 Apr 27.

50.

Regulation of mitochondrial protein import by cytosolic kinases.

Schmidt O, Harbauer AB, Rao S, Eyrich B, Zahedi RP, Stojanovski D, Schönfisch B, Guiard B, Sickmann A, Pfanner N, Meisinger C.

Cell. 2011 Jan 21;144(2):227-39. doi: 10.1016/j.cell.2010.12.015. Epub 2011 Jan 6.

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