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Items: 37

1.

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling.

V'kovski P, Gerber M, Kelly J, Pfaender S, Ebert N, Braga Lagache S, Simillion C, Portmann J, Stalder H, Gaschen V, Bruggmann R, Stoffel MH, Heller M, Dijkman R, Thiel V.

Elife. 2019 Jan 11;8. pii: e42037. doi: 10.7554/eLife.42037.

2.

Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection.

Alves MP, Vielle NJ, Thiel V, Pfaender S.

Viruses. 2018 Oct 30;10(11). pii: E593. doi: 10.3390/v10110593. Review.

3.

The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor.

García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01206-18. doi: 10.1128/AAC.01206-18. Print 2018 Nov.

4.

Comparison of Different In Situ Hybridization Techniques for the Detection of Various RNA and DNA Viruses.

Pfankuche VM, Hahn K, Bodewes R, Hansmann F, Habierski A, Haverkamp AK, Pfaender S, Walter S, Baechlein C, Postel A, Steinmann E, Becher P, Osterhaus A, Baumgärtner W, Puff C.

Viruses. 2018 Jul 20;10(7). pii: E384. doi: 10.3390/v10070384.

5.

Environmental Stability and Infectivity of Hepatitis C Virus (HCV) in Different Human Body Fluids.

Pfaender S, Helfritz FA, Siddharta A, Todt D, Behrendt P, Heyden J, Riebesehl N, Willmann W, Steinmann J, Münch J, Ciesek S, Steinmann E.

Front Microbiol. 2018 Mar 27;9:504. doi: 10.3389/fmicb.2018.00504. eCollection 2018.

6.

Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry.

Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meuleman P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T.

Antiviral Res. 2017 Nov;147:19-28. doi: 10.1016/j.antiviral.2017.09.006. Epub 2017 Sep 18.

PMID:
28923507
7.

Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC.

Sauer AK, Pfaender S, Hagmeyer S, Tarana L, Mattes AK, Briel F, Küry S, Boeckers TM, Grabrucker AM.

Biometals. 2017 Oct;30(5):643-661. doi: 10.1007/s10534-017-0033-y. Epub 2017 Jul 17.

8.

Frequent occurrence of nonprimate hepacivirus infections in Thoroughbred breeding horses - A cross-sectional study for the occurrence of infections and potential risk factors.

Reichert C, Campe A, Walter S, Pfaender S, Welsch K, Ruddat I, Sieme H, Feige K, Steinmann E, Cavalleri JMV.

Vet Microbiol. 2017 May;203:315-322. doi: 10.1016/j.vetmic.2017.03.030. Epub 2017 Apr 4.

PMID:
28619163
9.

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch MP, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E.

J Infect Dis. 2017 Mar 15;215(6):902-906. doi: 10.1093/infdis/jix046.

10.

Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.

Pfaender S, Sauer AK, Hagmeyer S, Mangus K, Linta L, Liebau S, Bockmann J, Huguet G, Bourgeron T, Boeckers TM, Grabrucker AM.

Sci Rep. 2017 Mar 27;7:45190. doi: 10.1038/srep45190.

11.

Immune protection against reinfection with nonprimate hepacivirus.

Pfaender S, Walter S, Grabski E, Todt D, Bruening J, Romero-Brey I, Gather T, Brown RJ, Hahn K, Puff C, Pfankuche VM, Hansmann F, Postel A, Becher P, Thiel V, Kalinke U, Wagner B, Bartenschlager R, Baumgärtner W, Feige K, Pietschmann T, Cavalleri JM, Steinmann E.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2430-E2439. doi: 10.1073/pnas.1619380114. Epub 2017 Mar 8.

12.

Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization.

Pfaender S, Vielle NJ, Ebert N, Steinmann E, Alves MP, Thiel V.

Virus Res. 2017 Jan 15;228:58-60. doi: 10.1016/j.virusres.2016.11.025. Epub 2016 Nov 23.

13.

Inactivation of HCV and HIV by microwave: a novel approach for prevention of virus transmission among people who inject drugs.

Siddharta A, Pfaender S, Malassa A, Doerrbecker J, Anggakusuma, Engelmann M, Nugraha B, Steinmann J, Todt D, Vondran FW, Mateu-Gelabert P, Goffinet C, Steinmann E.

Sci Rep. 2016 Nov 18;6:36619. doi: 10.1038/srep36619.

14.

Differential Infection Patterns and Recent Evolutionary Origins of Equine Hepaciviruses in Donkeys.

Walter S, Rasche A, Moreira-Soto A, Pfaender S, Bletsa M, Corman VM, Aguilar-Setien A, García-Lacy F, Hans A, Todt D, Schuler G, Shnaiderman-Torban A, Steinman A, Roncoroni C, Veneziano V, Rusenova N, Sandev N, Rusenov A, Zapryanova D, García-Bocanegra I, Jores J, Carluccio A, Veronesi MC, Cavalleri JMV, Drosten C, Lemey P, Steinmann E, Drexler JF.

J Virol. 2016 Dec 16;91(1). pii: e01711-16. doi: 10.1128/JVI.01711-16. Print 2017 Jan 1.

15.

Acute and chronic infections with nonprimate hepacivirus in young horses.

Gather T, Walter S, Pfaender S, Todt D, Feige K, Steinmann E, Cavalleri JM.

Vet Res. 2016 Sep 22;47(1):97.

16.

Vertical transmission of hepatitis C virus-like non-primate hepacivirus in horses.

Gather T, Walter S, Todt D, Pfaender S, Brown RJ, Postel A, Becher P, Moritz A, Hansmann F, Baumgaertner W, Feige K, Steinmann E, Cavalleri JV.

J Gen Virol. 2016 Oct;97(10):2540-2551. doi: 10.1099/jgv.0.000561. Epub 2016 Jul 26.

PMID:
27461949
17.

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner.

Pfaender S, Grabski E, Detje CN, Riebesehl N, Lienenklaus S, Steinmann E, Kalinke U, Pietschmann T.

PLoS Pathog. 2016 Jul 6;12(7):e1005736. doi: 10.1371/journal.ppat.1005736. eCollection 2016 Jul.

18.

Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells.

Pfaender S, Föhr K, Lutz AK, Putz S, Achberger K, Linta L, Liebau S, Boeckers TM, Grabrucker AM.

Neural Plast. 2016;2016:3760702. doi: 10.1155/2016/3760702. Epub 2016 May 9.

19.

Prevention strategies for blood-borne viruses-in the Era of vaccines, direct acting antivirals and antiretroviral therapy.

Pfaender S, von Hahn T, Steinmann J, Ciesek S, Steinmann E.

Rev Med Virol. 2016 Sep;26(5):330-9. doi: 10.1002/rmv.1890. Epub 2016 May 17. Review.

20.

Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7.

Walter S, Bollenbach A, Doerrbecker J, Pfaender S, Brown RJP, Vieyres G, Scott C, Foster R, Kumar A, Zitzmann N, Griffin S, Penin F, Pietschmann T, Steinmann E.

J Virol. 2016 Apr 29;90(10):5075-5089. doi: 10.1128/JVI.00132-16. Print 2016 May 15.

21.

Frequent presence of hepaci and pegiviruses in commercial equine serum pools.

Postel A, Cavalleri JM, Pfaender S, Walter S, Steinmann E, Fischer N, Feige K, Haas L, Becher P.

Vet Microbiol. 2016;182:8-14. doi: 10.1016/j.vetmic.2015.10.032. Epub 2015 Nov 1.

PMID:
26711022
22.

Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.

Walker A, Skibbe K, Steinmann E, Pfaender S, Kuntzen T, Megger DA, Groten S, Sitek B, Lauer GM, Kim AY, Pietschmann T, Allen TM, Timm J.

J Virol. 2015 Oct 7;90(1):33-42. doi: 10.1128/JVI.01993-15. Print 2016 Jan 1.

23.

Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo.

Chhabra R, Ruozi B, Vilella A, Belletti D, Mangus K, Pfaender S, Sarowar T, Boeckers TM, Zoli M, Forni F, Vandelli MA, Tosi G, Grabrucker AM.

CNS Neurol Disord Drug Targets. 2015;14(8):1041-53.

PMID:
26295815
24.

Host cell mTORC1 is required for HCV RNA replication.

Stöhr S, Costa R, Sandmann L, Westhaus S, Pfaender S, Anggakusuma, Dazert E, Meuleman P, Vondran FW, Manns MP, Steinmann E, von Hahn T, Ciesek S.

Gut. 2016 Dec;65(12):2017-2028. doi: 10.1136/gutjnl-2014-308971. Epub 2015 Aug 14.

25.

Assessment of cross-species transmission of hepatitis C virus-related non-primate hepacivirus in a population of humans at high risk of exposure.

Pfaender S, Walter S, Todt D, Behrendt P, Doerrbecker J, Wölk B, Engelmann M, Gravemann U, Seltsam A, Steinmann J, Burbelo PD, Klawonn F, Feige K, Pietschmann T, Cavalleri JM, Steinmann E.

J Gen Virol. 2015 Sep;96(9):2636-42. doi: 10.1099/vir.0.000208. Epub 2015 Jun 3.

26.

Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus-induced interferon alpha responses of plasmacytoid dendritic cells.

Grabski E, Wappler I, Pfaender S, Steinmann E, Haid S, Dzionek A, Pietschmann T, Kalinke U.

J Virol. 2015 Mar;89(6):3200-8. doi: 10.1128/JVI.03229-14. Epub 2014 Dec 31.

27.

Mechanisms of methods for hepatitis C virus inactivation.

Pfaender S, Brinkmann J, Todt D, Riebesehl N, Steinmann J, Steinmann J, Pietschmann T, Steinmann E.

Appl Environ Microbiol. 2015 Mar;81(5):1616-21. doi: 10.1128/AEM.03580-14. Epub 2014 Dec 19.

28.

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses.

Pfaender S, Cavalleri JM, Walter S, Doerrbecker J, Campana B, Brown RJ, Burbelo PD, Postel A, Hahn K, Anggakusuma, Riebesehl N, Baumgärtner W, Becher P, Heim MH, Pietschmann T, Feige K, Steinmann E.

Hepatology. 2015 Feb;61(2):447-59. doi: 10.1002/hep.27440. Epub 2015 Jan 5.

PMID:
25212983
29.

Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses.

Baecker T, Mangus K, Pfaender S, Chhabra R, Boeckers TM, Grabrucker AM.

Biometals. 2014 Aug;27(4):715-30. doi: 10.1007/s10534-014-9764-1. Epub 2014 Jul 10.

PMID:
25007851
30.

Characterization of biometal profiles in neurological disorders.

Pfaender S, Grabrucker AM.

Metallomics. 2014 May;6(5):960-77. doi: 10.1039/c4mt00008k. Review.

PMID:
24643462
31.

Natural reservoirs for homologs of hepatitis C virus.

Pfaender S, Brown RJ, Pietschmann T, Steinmann E.

Emerg Microbes Infect. 2014 Mar;3(3):e21. doi: 10.1038/emi.2014.19. Epub 2014 Mar 26. Review.

32.

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders.

Grabrucker S, Jannetti L, Eckert M, Gaub S, Chhabra R, Pfaender S, Mangus K, Reddy PP, Rankovic V, Schmeisser MJ, Kreutz MR, Ehret G, Boeckers TM, Grabrucker AM.

Brain. 2014 Jan;137(Pt 1):137-52. doi: 10.1093/brain/awt303. Epub 2013 Nov 25.

PMID:
24277719
33.

Inactivation of hepatitis C virus infectivity by human breast milk.

Pfaender S, Heyden J, Friesland M, Ciesek S, Ejaz A, Steinmann J, Steinmann J, Malarski A, Stoiber H, Tsiavaliaris G, Bader W, Jahreis G, Pietschmann T, Steinmann E.

J Infect Dis. 2013 Dec 15;208(12):1943-52. doi: 10.1093/infdis/jit519. Epub 2013 Sep 24.

PMID:
24068703
34.

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells.

Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E.

Gut. 2014 Jul;63(7):1137-49.

PMID:
23903236
35.

Thermostability of seven hepatitis C virus genotypes in vitro and in vivo.

Doerrbecker J, Meuleman P, Kang J, Riebesehl N, Wilhelm C, Friesland M, Pfaender S, Steinmann J, Pietschmann T, Steinmann E.

J Viral Hepat. 2013 Jul;20(7):478-85. doi: 10.1111/jvh.12055. Epub 2013 Jan 17.

PMID:
23730841
36.

Hepatocytes that express variants of cyclophilin A are resistant to HCV infection and replication.

von Hahn T, Schiene-Fischer C, Van ND, Pfaender S, Karavul B, Steinmann E, Potthoff A, Strassburg C, Hamdi N, Abdelaziz AI, Sarrazin C, Müller T, Berg T, Trépo E, Wedemeyer H, Manns MP, Pietschmann T, Ciesek S.

Gastroenterology. 2012 Aug;143(2):439-47.e1. doi: 10.1053/j.gastro.2012.04.053. Epub 2012 May 8.

PMID:
22580540
37.

[Primary prevention of gastroduodenal ulcer: what is the evidence?].

Pfaender S, Perrier A, Nendaz M.

Rev Med Suisse. 2006 Oct 18;2(83):2337-8, 2340, 2342-3. Review. French.

PMID:
17112084

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