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Items: 9

1.

Continuous low-dose infusion of patupilone increases the therapeutic index in mouse and rat tumour models.

Becquet M, Laborde L, Texier C, Sterker D, Gschwind HP, Pfaar U, Wartmann M, O'Reilly TM, McSheehy PM.

Anticancer Drugs. 2018 Aug;29(7):691-701. doi: 10.1097/CAD.0000000000000639.

PMID:
29734209
2.

Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite.

Krauser JA, Jin Y, Walles M, Pfaar U, Sutton J, Wiesmann M, Graf D, Pflimlin-Fritschy V, Wolf T, Camenisch G, Swart P.

Xenobiotica. 2015 Feb;45(2):107-23. doi: 10.3109/00498254.2014.945988. Epub 2014 Sep 2.

PMID:
25180976
3.

Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800.

Massey AJ, Schoepfer J, Brough PA, Brueggen J, Chène P, Drysdale MJ, Pfaar U, Radimerski T, Ruetz S, Schweitzer A, Wood M, Garcia-Echeverria C, Jensen MR.

Mol Cancer Ther. 2010 Apr;9(4):906-19. doi: 10.1158/1535-7163.MCT-10-0055. Epub 2010 Apr 6.

4.

Biodistribution and plasma protein binding of zoledronic acid.

Weiss HM, Pfaar U, Schweitzer A, Wiegand H, Skerjanec A, Schran H.

Drug Metab Dispos. 2008 Oct;36(10):2043-9. doi: 10.1124/dmd.108.021071. Epub 2008 Jul 14.

5.

A microplate solid scintillation counter as a radioactivity detector for high performance liquid chromatography in drug metabolism: validation and applications.

Bruin GJ, Waldmeier F, Boernsen KO, Pfaar U, Gross G, Zollinger M.

J Chromatogr A. 2006 Nov 10;1133(1-2):184-94. Epub 2006 Sep 12.

PMID:
16970958
6.

Metabolism and disposition of imatinib mesylate in healthy volunteers.

Gschwind HP, Pfaar U, Waldmeier F, Zollinger M, Sayer C, Zbinden P, Hayes M, Pokorny R, Seiberling M, Ben-Am M, Peng B, Gross G.

Drug Metab Dispos. 2005 Oct;33(10):1503-12. Epub 2005 Jul 8.

7.

Development and validation of a highly sensitive RIA for zoledronic acid, a new potent heterocyclic bisphosphonate, in human serum, plasma and urine.

Legay F, Gauron S, Deckert F, Gosset G, Pfaar U, Ravera C, Wiegand H, Schran H.

J Pharm Biomed Anal. 2002 Nov 7;30(4):897-911.

PMID:
12408879
9.

Characterization of a novel diclofenac metabolite in human urine by capillary gas chromatography-negative chemical ionization mass spectrometry.

Blum W, Faigle JW, Pfaar U, Sallmann A.

J Chromatogr B Biomed Appl. 1996 Oct 25;685(2):251-63.

PMID:
8953166

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