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Items: 14


A single combination gene therapy treats multiple age-related diseases.

Davidsohn N, Pezone M, Vernet A, Graveline A, Oliver D, Slomovic S, Punthambaker S, Sun X, Liao R, Bonventre JV, Church GM.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23505-23511. doi: 10.1073/pnas.1910073116. Epub 2019 Nov 4. Erratum in: Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):790.


Replenishable drug depot to combat post-resection cancer recurrence.

Brudno Y, Pezone MJ, Snyder TK, Uzun O, Moody CT, Aizenberg M, Mooney DJ.

Biomaterials. 2018 Sep;178:373-382. doi: 10.1016/j.biomaterials.2018.05.005. Epub 2018 May 6.


Using Engineered Bacteria to Characterize Infection Dynamics and Antibiotic Effects In Vivo.

Certain LK, Way JC, Pezone MJ, Collins JJ.

Cell Host Microbe. 2017 Sep 13;22(3):263-268.e4. doi: 10.1016/j.chom.2017.08.001. Epub 2017 Aug 31.


Nitrogen dioxide reducing ascorbic acid technologies in the ventilator circuit leads to uniform NO concentration during inspiration.

Pezone MJ, Wakim MG, Denton RJ, Gamero LG, Roscigno RF, Gilbert RJ, Lovich MA.

Nitric Oxide. 2016 Aug 31;58:42-50. doi: 10.1016/j.niox.2016.06.001. Epub 2016 Jun 2.


Infusion System Architecture Impacts the Ability of Intensive Care Nurses to Maintain Hemodynamic Stability in a Living Swine Simulator.

Pezone MJ, Peterfreund RA, Maslov MY, Govindaswamy RR, Lovich MA.

Anesthesiology. 2016 May;124(5):1077-85. doi: 10.1097/ALN.0000000000001075.


Infusion system carrier flow perturbations and dead-volume: large effects on drug delivery in vitro and hemodynamic responses in a swine model.

Lovich MA, Pezone MJ, Maslov MY, Murray MR, Wakim MG, Peterfreund RA.

Anesth Analg. 2015 Jun;120(6):1255-63. doi: 10.1213/ANE.0000000000000654.


Vascular Dilation, Tachycardia, and Increased Inotropy Occur Sequentially with Increasing Epinephrine Dose Rate, Plasma and Myocardial Concentrations, and cAMP.

Maslov MY, Wei AE, Pezone MJ, Edelman ER, Lovich MA.

Heart Lung Circ. 2015 Sep;24(9):912-8. doi: 10.1016/j.hlc.2015.02.012. Epub 2015 Feb 23.


Inhaled Nitric Oxide Augments Left Ventricular Assist Device Capacity by Ameliorating Secondary Right Ventricular Failure.

Lovich MA, Pezone MJ, Wakim MG, Denton RJ, Maslov MY, Murray MR, Tsukada H, Agnihotri AK, Roscigno RF, Gamero LG, Gilbert RJ.

ASAIO J. 2015 Jul-Aug;61(4):379-85. doi: 10.1097/MAT.0000000000000211.


Myocardial drug distribution generated from local epicardial application: potential impact of cardiac capillary perfusion in a swine model using epinephrine.

Maslov MY, Edelman ER, Pezone MJ, Wei AE, Wakim MG, Murray MR, Tsukada H, Gerogiannis IS, Groothuis A, Lovich MA.

J Control Release. 2014 Nov 28;194:257-65. doi: 10.1016/j.jconrel.2014.09.012. Epub 2014 Sep 16.


Use of pressure-volume conductance catheters in real-time cardiovascular experimentation.

Wei AE, Maslov MY, Pezone MJ, Edelman ER, Lovich MA.

Heart Lung Circ. 2014 Nov;23(11):1059-69. doi: 10.1016/j.hlc.2014.04.130. Epub 2014 May 22.


Drug infusion system manifold dead-volume impacts the delivery response time to changes in infused medication doses in vitro and also in vivo in anesthetized swine.

Lovich MA, Wakim MG, Wei A, Parker MJ, Maslov MY, Pezone MJ, Tsukada H, Peterfreund RA.

Anesth Analg. 2013 Dec;117(6):1313-8. doi: 10.1213/ANE.0b013e3182a76f3b.


Divergent modification of low-dose ⁵⁶Fe-particle and proton radiation on skeletal muscle.

Shtifman A, Pezone MJ, Sasi SP, Agarwal A, Gee H, Song J, Perepletchikov A, Yan X, Kishore R, Goukassian DA.

Radiat Res. 2013 Nov;180(5):455-64. doi: 10.1667/RR3329.1. Epub 2013 Oct 17.


High concentrations of drug in target tissues following local controlled release are utilized for both drug distribution and biologic effect: an example with epicardial inotropic drug delivery.

Maslov MY, Edelman ER, Wei AE, Pezone MJ, Lovich MA.

J Control Release. 2013 Oct 28;171(2):201-7. doi: 10.1016/j.jconrel.2013.06.038. Epub 2013 Jul 18.


Mitochondrial dysfunction in skeletal muscle of amyloid precursor protein-overexpressing mice.

Boncompagni S, Moussa CE, Levy E, Pezone MJ, Lopez JR, Protasi F, Shtifman A.

J Biol Chem. 2012 Jun 8;287(24):20534-44. doi: 10.1074/jbc.M112.359588. Epub 2012 Apr 19.

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