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Items: 25

1.

Hydrazone linked doxorubicin-PLA prodrug nanoparticles with high drug loading.

Gatti S, Agostini A, Palmiero UC, Colombo C, Peviani M, Biffi A, Moscatelli D.

Nanotechnology. 2018 Jul 27;29(30):305602. doi: 10.1088/1361-6528/aac0d3. Epub 2018 Apr 27.

PMID:
29701613
2.

Metallothioneins are neuroprotective agents in lysosomal storage disorders.

Cavalca E, Cesani M, Gifford JC, Sena-Esteves M, Terreni MR, Leoncini G, Peviani M, Biffi A.

Ann Neurol. 2018 Feb;83(2):418-432. doi: 10.1002/ana.25161. Epub 2018 Feb 15.

PMID:
29369397
3.

Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells.

Capotondo A, Milazzo R, Garcia-Manteiga JM, Cavalca E, Montepeloso A, Garrison BS, Peviani M, Rossi DJ, Biffi A.

Sci Adv. 2017 Dec 6;3(12):e1701211. doi: 10.1126/sciadv.1701211. eCollection 2017 Dec.

4.

T1-Weighted Dynamic Contrast-Enhanced MRI Is a Noninvasive Marker of Epidermal Growth Factor Receptor vIII Status in Cancer Stem Cell-Derived Experimental Glioblastomas.

Politi LS, Brugnara G, Castellano A, Cadioli M, Altabella L, Peviani M, Mazzoleni S, Falini A, Galli R.

AJNR Am J Neuroradiol. 2016 Jun;37(6):E49-51. doi: 10.3174/ajnr.A4774. Epub 2016 Mar 17. No abstract available.

5.

Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.

Marra A, Rossi D, Pignataro L, Bigogno C, Canta A, Oggioni N, Malacrida A, Corbo M, Cavaletti G, Peviani M, Curti D, Dondio G, Collina S.

Future Med Chem. 2016;8(3):287-95. doi: 10.4155/fmc.15.191. Epub 2016 Feb 22.

PMID:
26898712
6.

Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.

Marra A, Rossi D, Maggi L, Corana F, Mannucci B, Peviani M, Curti D, Collina S.

Biomed Chromatogr. 2016 Apr;30(4):645-51. doi: 10.1002/bmc.3609. Epub 2015 Oct 8.

PMID:
26447185
7.

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

Marino M, Papa S, Crippa V, Nardo G, Peviani M, Cheroni C, Trolese MC, Lauranzano E, Bonetto V, Poletti A, DeBiasi S, Ferraiuolo L, Shaw PJ, Bendotti C.

Neurobiol Aging. 2015 Jan;36(1):492-504. doi: 10.1016/j.neurobiolaging.2014.06.026. Epub 2014 Jul 2.

PMID:
25085783
8.

Defining peripheral nervous system dysfunction in the SOD-1G93A transgenic rat model of amyotrophic lateral sclerosis.

Riva N, Chaabane L, Peviani M, Ungaro D, Domi T, Dina G, Bianchi F, Spano G, Cerri F, Podini P, Corbo M, Carro UD, Comi G, Bendotti C, Quattrini A.

J Neuropathol Exp Neurol. 2014 Jul;73(7):658-70. doi: 10.1097/NEN.0000000000000081.

PMID:
24918640
9.

Increased axonal ribosome numbers is an early event in the pathogenesis of amyotrophic lateral sclerosis.

Verheijen MH, Peviani M, Hendricusdottir R, Bell EM, Lammens M, Smit AB, Bendotti C, van Minnen J.

PLoS One. 2014 Jan 30;9(1):e87255. doi: 10.1371/journal.pone.0087255. eCollection 2014.

10.

Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury.

Papa S, Ferrari R, De Paola M, Rossi F, Mariani A, Caron I, Sammali E, Peviani M, Dell'Oro V, Colombo C, Morbidelli M, Forloni G, Perale G, Moscatelli D, Veglianese P.

J Control Release. 2014 Jan 28;174:15-26. doi: 10.1016/j.jconrel.2013.11.001. Epub 2013 Nov 10.

PMID:
24225226
11.

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.

Peviani M, Salvaneschi E, Bontempi L, Petese A, Manzo A, Rossi D, Salmona M, Collina S, Bigini P, Curti D.

Neurobiol Dis. 2014 Feb;62:218-32. doi: 10.1016/j.nbd.2013.10.010. Epub 2013 Oct 16.

PMID:
24141020
12.

Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury.

Papa S, Rossi F, Ferrari R, Mariani A, De Paola M, Caron I, Fiordaliso F, Bisighini C, Sammali E, Colombo C, Gobbi M, Canovi M, Lucchetti J, Peviani M, Morbidelli M, Forloni G, Perale G, Moscatelli D, Veglianese P.

ACS Nano. 2013 Nov 26;7(11):9881-95. doi: 10.1021/nn4036014. Epub 2013 Oct 18.

PMID:
24138479
13.

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

Rossi D, Pedrali A, Marra A, Pignataro L, Schepmann D, Wünsch B, Ye L, Leuner K, Peviani M, Curti D, Azzolina O, Collina S.

Chirality. 2013 Nov;25(11):814-22. doi: 10.1002/chir.22223. Epub 2013 Sep 7.

PMID:
24038285
14.

Specific induction of Akt3 in spinal cord motor neurons is neuroprotective in a mouse model of familial amyotrophic lateral sclerosis.

Peviani M, Tortarolo M, Battaglia E, Piva R, Bendotti C.

Mol Neurobiol. 2014 Feb;49(1):136-48. doi: 10.1007/s12035-013-8507-6. Epub 2013 Jul 20.

PMID:
23873136
15.

Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: promising neuroprotective agents acting as σ₁ receptor agonists.

Rossi D, Pedrali A, Gaggeri R, Marra A, Pignataro L, Laurini E, Dal Col V, Fermeglia M, Pricl S, Schepmann D, Wünsch B, Peviani M, Curti D, Collina S.

ChemMedChem. 2013 Sep;8(9):1514-27. doi: 10.1002/cmdc.201300218. Epub 2013 Jul 5.

PMID:
23832823
16.

Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.

Rossi D, Marra A, Picconi P, Serra M, Catenacci L, Sorrenti M, Laurini E, Fermeglia M, Pricl S, Brambilla S, Almirante N, Peviani M, Curti D, Collina S.

Bioorg Med Chem. 2013 May 1;21(9):2577-86. doi: 10.1016/j.bmc.2013.02.029. Epub 2013 Feb 26.

PMID:
23498917
17.

Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration.

De Paola M, Mariani A, Bigini P, Peviani M, Ferrara G, Molteni M, Gemma S, Veglianese P, Castellaneta V, Boldrin V, Rossetti C, Chiabrando C, Forloni G, Mennini T, Fanelli R.

Mol Med. 2012 Sep 7;18:971-81. doi: 10.2119/molmed.2012.00020.

18.

p38αMAPK interacts with and inhibits RARα: suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells.

Gianni M, Peviani M, Bruck N, Rambaldi A, Borleri G, Terao M, Kurosaki M, Paroni G, Rochette-Egly C, Garattini E.

Leukemia. 2012 Aug;26(8):1850-61. doi: 10.1038/leu.2012.50. Epub 2012 Feb 22.

PMID:
22354283
19.

Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons.

Peviani M, Kurosaki M, Terao M, Lidonnici D, Gensano F, Battaglia E, Tortarolo M, Piva R, Bendotti C.

J Neurosci Methods. 2012 Mar 30;205(1):139-47. doi: 10.1016/j.jneumeth.2011.12.024. Epub 2012 Jan 8.

PMID:
22245491
20.

Multiple drug delivery hydrogel system for spinal cord injury repair strategies.

Perale G, Rossi F, Santoro M, Peviani M, Papa S, Llupi D, Torriani P, Micotti E, Previdi S, Cervo L, Sundström E, Boccaccini AR, Masi M, Forloni G, Veglianese P.

J Control Release. 2012 Apr 30;159(2):271-80. doi: 10.1016/j.jconrel.2011.12.025. Epub 2011 Dec 29.

PMID:
22227024
21.

Identification of a potent and selective σ₁ receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells.

Rossi D, Pedrali A, Urbano M, Gaggeri R, Serra M, Fernández L, Fernández M, Caballero J, Ronsisvalle S, Prezzavento O, Schepmann D, Wuensch B, Peviani M, Curti D, Azzolina O, Collina S.

Bioorg Med Chem. 2011 Nov 1;19(21):6210-24. doi: 10.1016/j.bmc.2011.09.016. Epub 2011 Sep 14.

PMID:
21967807
22.

Unraveling the complexity of amyotrophic lateral sclerosis: recent advances from the transgenic mutant SOD1 mice.

Peviani M, Caron I, Pizzasegola C, Gensano F, Tortarolo M, Bendotti C.

CNS Neurol Disord Drug Targets. 2010 Aug;9(4):491-503. Review.

PMID:
20522008
23.

Lack of changes in the PI3K/AKT survival pathway in the spinal cord motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Peviani M, Cheroni C, Troglio F, Quarto M, Pelicci G, Bendotti C.

Mol Cell Neurosci. 2007 Apr;34(4):592-602. Epub 2007 Jan 11.

PMID:
17303436
24.

Inter- and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase.

Bendotti C, Bao Cutrona M, Cheroni C, Grignaschi G, Lo Coco D, Peviani M, Tortarolo M, Veglianese P, Zennaro E.

Neurodegener Dis. 2005;2(3-4):128-34. Review.

PMID:
16909017
25.

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