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Antimicrob Agents Chemother. 2005 Jul;49(7):3018-20.

Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York: epidemiology and recommendations for detection.

Author information

1
Department of Medicine, SUNY-Downstate Medical Center, Brooklyn, New Yoek 11203, USA.

Abstract

Among 257 isolates of Klebsiella pneumoniae collected in Brooklyn, NY, 24% were found to possess bla(KPC). Clinical microbiology laboratories that used automated broth microdilution systems reported 15% of the KPC-possessing isolates as susceptible to imipenem. The imipenem MIC was found to be markedly affected by the inoculum. For accurate detection of KPC-possessing K. pneumoniae, particular attention should be paid to proper inoculum preparation for broth-based susceptibility methods. In addition, using ertapenem or meropenem for class reporting of carbapenem susceptibility will improve detection.

PMID:
15980389
PMCID:
PMC1168646
DOI:
10.1128/AAC.49.7.3018-3020.2005
[Indexed for MEDLINE]
Free PMC Article

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