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Items: 1 to 50 of 202


Adjuvant Strategies for More Effective Tuberculosis Vaccine Immunity.

Stewart E, Triccas JA, Petrovsky N.

Microorganisms. 2019 Aug 12;7(8). pii: E255. doi: 10.3390/microorganisms7080255. Review.


Randomized controlled trial demonstrating the benefits of delta inulin adjuvanted immunotherapy in patients with bee venom allergy.

Heddle R, Smith A, Woodman R, Hissaria P, Petrovsky N.

J Allergy Clin Immunol. 2019 Aug;144(2):504-513.e16. doi: 10.1016/j.jaci.2019.03.035. Epub 2019 Jul 9.


Neonatal vaccine effectiveness and the role of adjuvants.

Sakala IG, Eichinger KM, Petrovsky N.

Expert Rev Clin Immunol. 2019 Aug;15(8):869-878. doi: 10.1080/1744666X.2019.1642748. Epub 2019 Jul 25.


Review of polysaccharide particle-based functional drug delivery.

Barclay TG, Day CM, Petrovsky N, Garg S.

Carbohydr Polym. 2019 Oct 1;221:94-112. doi: 10.1016/j.carbpol.2019.05.067. Epub 2019 May 26. Review.


Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes.

Afinjuomo F, Barclay TG, Parikh A, Song Y, Chung R, Wang L, Liu L, Hayball JD, Petrovsky N, Garg S.

Pharmaceutics. 2019 May 22;11(5). pii: E243. doi: 10.3390/pharmaceutics11050243.


The effects of positive schizotypy and sleep deprivation on prepulse inhibition.

Meyhöfer I, Ettinger U, Faiola E, Petrovsky N, Kumari V.

Schizophr Res. 2019 Jul;209:284-285. doi: 10.1016/j.schres.2019.05.017. Epub 2019 May 16. No abstract available.


Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy.

Wanandy T, Honda-Okubo Y, Davies NW, Rose HE, Heddle RJ, Brown SGA, Woodman RJ, Petrovsky N, Wiese MD.

J Pharm Biomed Anal. 2019 Aug 5;172:1-8. doi: 10.1016/j.jpba.2019.04.017. Epub 2019 Apr 9.


A Microfluidic Tumor-on-a-Chip for Assessing Multifunctional Liposomes' Tumor Targeting and Anticancer Efficacy.

Ran R, Wang HF, Hou F, Liu Y, Hui Y, Petrovsky N, Zhang F, Zhao CX.

Adv Healthc Mater. 2019 Apr;8(8):e1900015. doi: 10.1002/adhm.201900015. Epub 2019 Mar 14.


Calcium Signaling As a Therapeutic Target for Liver Steatosis.

Ali ES, Petrovsky N.

Trends Endocrinol Metab. 2019 Apr;30(4):270-281. doi: 10.1016/j.tem.2019.02.005. Epub 2019 Mar 5. Review.


Efficacy of an Adjuvanted Middle East Respiratory Syndrome Coronavirus Spike Protein Vaccine in Dromedary Camels and Alpacas.

Adney DR, Wang L, van Doremalen N, Shi W, Zhang Y, Kong WP, Miller MR, Bushmaker T, Scott D, de Wit E, Modjarrad K, Petrovsky N, Graham BS, Bowen RA, Munster VJ.

Viruses. 2019 Mar 2;11(3). pii: E212. doi: 10.3390/v11030212.


3D reconstruction of CT scans aid in preoperative planning for sarcomatoid renal cancer: A case report and mini-review.

Glybochko PV, Alyaev YG, Khokhlachev SB, Fiev DN, Shpot EV, Petrovsky NV, Zhang D, Proskura AV, Yurova M, Matz EL, Wang X, Atala A, Zhang Y, Butnaru DV.

J Xray Sci Technol. 2019;27(2):389-395. doi: 10.3233/XST-180387.


Mitochondrial haplogroups are not associated with diabetic retinopathy in a large Australian and British Caucasian sample.

Liu E, Kaidonis G, Gillies MC, Abhary S, Essex RW, Chang JH, Pal B, Daniell M, Lake S, Gilhotra J, Petrovsky N, Hewitt AW, Jenkins A, Lamoureux EL, Gleadle JM, Burdon KP, Craig JE.

Sci Rep. 2019 Jan 24;9(1):612. doi: 10.1038/s41598-018-37388-8.


Microfluidic formation of core-shell alginate microparticles for protein encapsulation and controlled release.

Yu L, Sun Q, Hui Y, Seth A, Petrovsky N, Zhao CX.

J Colloid Interface Sci. 2019 Mar 15;539:497-503. doi: 10.1016/j.jcis.2018.12.075. Epub 2018 Dec 19.


Effects of nicotine and atomoxetine on brain function during response inhibition.

Kasparbauer AM, Petrovsky N, Schmidt PM, Trautner P, Weber B, Sträter B, Ettinger U.

Eur Neuropsychopharmacol. 2019 Dec;29(2):235-246. doi: 10.1016/j.euroneuro.2018.12.004. Epub 2018 Dec 12.


The Safety of an Adjuvanted Autologous Cancer Vaccine Platform in Canine Cancer Patients.

Weir C, Oksa A, Millar J, Alexander M, Kynoch N, Walton-Weitz Z, Mackenzie-Wood P, Tam F, Richards H, Naylor R, Cheng K, Bennett P, Petrovsky N, Allavena R.

Vet Sci. 2018 Oct 12;5(4). pii: E87. doi: 10.3390/vetsci5040087.


Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge.

Tomar J, Biel C, de Haan CAM, Rottier PJM, Petrovsky N, Frijlink HW, Huckriede A, Hinrichs WLJ, Peeters B.

Eur J Pharm Biopharm. 2018 Dec;133:85-95. doi: 10.1016/j.ejpb.2018.10.008. Epub 2018 Oct 9.


Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge.

Tomar J, Patil HP, Bracho G, Tonnis WF, Frijlink HW, Petrovsky N, Vanbever R, Huckriede A, Hinrichs WLJ.

J Control Release. 2018 Oct 28;288:199-211. doi: 10.1016/j.jconrel.2018.09.006. Epub 2018 Sep 12.


Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy.

Graham PS, Kaidonis G, Abhary S, Gillies MC, Daniell M, Essex RW, Chang JH, Lake SR, Pal B, Jenkins AJ, Hewitt AW, Lamoureux EL, Hykin PG, Petrovsky N, Brown MA, Craig JE, Burdon KP.

BMC Med Genet. 2018 May 8;19(1):71. doi: 10.1186/s12881-018-0587-8.


Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats.

Mailybayeva A, Yespembetov B, Ryskeldinova S, Zinina N, Sansyzbay A, Renukaradhya GJ, Petrovsky N, Tabynov K.

PLoS One. 2017 Oct 12;12(10):e0186484. doi: 10.1371/journal.pone.0186484. eCollection 2017.


Advax4 delta inulin combination adjuvant together with ECMX, a fusion construct of four protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection.

de Paula Oliveira Santos B, Trentini MM, Machado RB, Rúbia Nunes Celes M, Kipnis A, Petrovsky N, Junqueira-Kipnis AP.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2967-2976. doi: 10.1080/21645515.2017.1368598.


Proteomic analysis of influenza haemagglutinin-specific antibodies following vaccination reveals convergent immunoglobulin variable region signatures.

Adamson PJ, Al Kindi MA, Wang JJ, Colella AD, Chataway TK, Petrovsky N, Gordon TP, Gordon DL.

Vaccine. 2017 Oct 9;35(42):5576-5580. doi: 10.1016/j.vaccine.2017.08.053. Epub 2017 Sep 6.


Delta inulin-based adjuvants promote the generation of polyfunctional CD4+ T cell responses and protection against Mycobacterium tuberculosis infection.

Counoupas C, Pinto R, Nagalingam G, Britton WJ, Petrovsky N, Triccas JA.

Sci Rep. 2017 Aug 17;7(1):8582. doi: 10.1038/s41598-017-09119-y.


DNA prime/protein boost vaccination elicits robust humoral response in rhesus macaques using oligomeric simian immunodeficiency virus envelope and Advax delta inulin adjuvant.

Menon V, Ayala VI, Rangaswamy SP, Kalisz I, Whitney S, Galmin L, Ashraf A, LaBranche C, Montefiori D, Petrovsky N, Kalyanaraman VS, Pal R.

J Gen Virol. 2017 Aug;98(8):2143-2155. doi: 10.1099/jgv.0.000863. Epub 2017 Jul 31.


Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant.

Wang L, Barclay T, Song Y, Joyce P, Sakala IG, Petrovsky N, Garg S.

Vaccine. 2017 Aug 3;35(34):4382-4388. doi: 10.1016/j.vaccine.2017.06.045. Epub 2017 Jul 1.


Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and pathology.

O'Meara CP, Armitage CW, Andrew DW, Kollipara A, Lycke NY, Potter AA, Gerdts V, Petrovsky N, Beagley KW.

Vaccine. 2017 Jul 5;35(31):3883-3888. doi: 10.1016/j.vaccine.2017.05.063. Epub 2017 Jun 8.


X-ray crystal structure of rivoglitazone bound to PPARγ and PPAR subtype selectivity of TZDs.

Rajapaksha H, Bhatia H, Wegener K, Petrovsky N, Bruning JB.

Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):1981-1991. doi: 10.1016/j.bbagen.2017.05.008. Epub 2017 May 9.


Sleep deprivation as an experimental model system for psychosis: Effects on smooth pursuit, prosaccades, and antisaccades.

Meyhöfer I, Kumari V, Hill A, Petrovsky N, Ettinger U.

J Psychopharmacol. 2017 Apr;31(4):418-433. doi: 10.1177/0269881116675511. Epub 2016 Nov 11.


Panblok-H1+advax H1N1/2009pdm vaccine: Insights into rapid development of a delta inulin adjuvanted recombinant pandemic influenza vaccine.

Honda-Okubo Y, Rajapaksha H, Sajkov D, Gordon D, Cox MMJ, Petrovsky N.

Hum Vaccin Immunother. 2017 Jun 3;13(6):1-11. doi: 10.1080/21645515.2017.1279765. Epub 2017 Feb 14.


Effects of nicotine on response inhibition and interference control.

Ettinger U, Faiola E, Kasparbauer AM, Petrovsky N, Chan RC, Liepelt R, Kumari V.

Psychopharmacology (Berl). 2017 Apr;234(7):1093-1111. doi: 10.1007/s00213-017-4542-8. Epub 2017 Feb 1.


Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines.

Hayashi M, Aoshi T, Haseda Y, Kobiyama K, Wijaya E, Nakatsu N, Igarashi Y, Standley DM, Yamada H, Honda-Okubo Y, Hara H, Saito T, Takai T, Coban C, Petrovsky N, Ishii KJ.

EBioMedicine. 2017 Feb;15:127-136. doi: 10.1016/j.ebiom.2016.11.015. Epub 2016 Dec 1.


Molecular Adjuvants for DNA Vaccines.

Li L, Petrovsky N.

Curr Issues Mol Biol. 2017;22:17-40. Epub 2016 Sep 20. Review.


Influenza immunization during pregnancy: Benefits for mother and infant.

Sakala IG, Honda-Okubo Y, Fung J, Petrovsky N.

Hum Vaccin Immunother. 2016 Dec;12(12):3065-3071. doi: 10.1080/21645515.2016.1215392. Epub 2016 Aug 5. Review.


Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens.

Ali ES, Rajapaksha H, Carr JM, Petrovsky N.

Antiviral Res. 2016 Sep;133:14-22. doi: 10.1016/j.antiviral.2016.07.006. Epub 2016 Jul 13. Review.


The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice.

Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D.

PLoS Negl Trop Dis. 2016 Jul 7;10(7):e0004797. doi: 10.1371/journal.pntd.0004797. eCollection 2016 Jul.


Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules.

Davtyan H, Zagorski K, Rajapaksha H, Hovakimyan A, Davtyan A, Petrushina I, Kazarian K, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A.

Sci Rep. 2016 Jul 1;6:28912. doi: 10.1038/srep28912.


Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax™ delta inulin adjuvant.

Gordon DL, Sajkov D, Honda-Okubo Y, Wilks SH, Aban M, Barr IG, Petrovsky N.

Vaccine. 2016 Jul 19;34(33):3780-6. doi: 10.1016/j.vaccine.2016.05.071. Epub 2016 Jun 21.



Petrovsky N.

Hum Vaccin Immunother. 2016 Nov;12(11):2726-2728. Epub 2016 May 31. No abstract available.


Physical characterization and in silico modeling of inulin polymer conformation during vaccine adjuvant particle formation.

Barclay TG, Rajapaksha H, Thilagam A, Qian G, Ginic-Markovic M, Cooper PD, Gerson A, Petrovsky N.

Carbohydr Polym. 2016 Jun 5;143:108-15. doi: 10.1016/j.carbpol.2016.01.062. Epub 2016 Jan 29.


Development of a SARS Coronavirus Vaccine from Recombinant Spike Protein Plus Delta Inulin Adjuvant.

McPherson C, Chubet R, Holtz K, Honda-Okubo Y, Barnard D, Cox M, Petrovsky N.

Methods Mol Biol. 2016;1403:269-84. doi: 10.1007/978-1-4939-3387-7_14.


Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.

Dooley J, Tian L, Schonefeldt S, Delghingaro-Augusto V, Garcia-Perez JE, Pasciuto E, Di Marino D, Carr EJ, Oskolkov N, Lyssenko V, Franckaert D, Lagou V, Overbergh L, Vandenbussche J, Allemeersch J, Chabot-Roy G, Dahlstrom JE, Laybutt DR, Petrovsky N, Socha L, Gevaert K, Jetten AM, Lambrechts D, Linterman MA, Goodnow CC, Nolan CJ, Lesage S, Schlenner SM, Liston A.

Nat Genet. 2016 May;48(5):519-27. doi: 10.1038/ng.3531. Epub 2016 Mar 21.


A single-nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients.

Kaidonis G, Gillies MC, Abhary S, Liu E, Essex RW, Chang JH, Pal B, Sivaprasad S, Pefkianaki M, Daniell M, Lake S, Petrovsky N, Hewitt AW, Jenkins A, Lamoureux EL, Gleadle JM, Craig JE, Burdon KP.

Acta Diabetol. 2016 Aug;53(4):643-50. doi: 10.1007/s00592-016-0850-4. Epub 2016 Mar 21.


Promoter polymorphism at the tumour necrosis factor/lymphotoxin-alpha locus is associated with type of diabetes but not with susceptibility to sight-threatening diabetic retinopathy.

Kaidonis G, Craig JE, Gillies MC, Abhary S, Essex RW, Chang JH, Pal B, Pefkianaki M, Daniell M, Lake S, Petrovsky N, Burdon KP.

Diab Vasc Dis Res. 2016 Mar;13(2):164-7. doi: 10.1177/1479164115616902. Epub 2016 Jan 28.


Molecular mechanisms for enhanced DNA vaccine immunogenicity.

Li L, Petrovsky N.

Expert Rev Vaccines. 2016;15(3):313-29. doi: 10.1586/14760584.2016.1124762. Epub 2015 Dec 28. Review.


Neurocognitive functioning in parents of schizophrenia patients: Attentional and executive performance vary with genetic loading.

Schulze-Rauschenbach S, Lennertz L, Ruhrmann S, Petrovsky N, Ettinger U, Pukrop R, Dreher J, Klosterkötter J, Maier W, Wagner M.

Psychiatry Res. 2015 Dec 30;230(3):885-91. doi: 10.1016/j.psychres.2015.11.031. Epub 2015 Nov 19.


Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample.

Bey K, Lennertz L, Markett S, Petrovsky N, Gallinat J, Gründer G, Spreckelmeyer KN, Wienker TF, Mobascher A, Dahmen N, Thuerauf N, Kornhuber J, Kiefer F, Toliat MR, Nürnberg P, Winterer G, Wagner M.

Eur Neuropsychopharmacol. 2016 Jan;26(1):150-155. doi: 10.1016/j.euroneuro.2015.11.007. Epub 2015 Nov 14.


Comparative Safety of Vaccine Adjuvants: A Summary of Current Evidence and Future Needs.

Petrovsky N.

Drug Saf. 2015 Nov;38(11):1059-74. doi: 10.1007/s40264-015-0350-4. Review.


Advax™, a novel microcrystalline polysaccharide particle engineered from delta inulin, provides robust adjuvant potency together with tolerability and safety.

Petrovsky N, Cooper PD.

Vaccine. 2015 Nov 4;33(44):5920-6. doi: 10.1016/j.vaccine.2015.09.030. Epub 2015 Sep 25. Review.


Novel nanoparticle vaccines for Listeriosis.

Calderon-Gonzalez R, Marradi M, Garcia I, Petrovsky N, Alvarez-Dominguez C.

Hum Vaccin Immunother. 2015;11(10):2501-3. doi: 10.1080/21645515.2015.1063756.


Advax delta inulin adjuvant overcomes immune immaturity in neonatal mice thereby allowing single-dose influenza vaccine protection.

Honda-Okubo Y, Ong CH, Petrovsky N.

Vaccine. 2015 Sep 11;33(38):4892-900. doi: 10.1016/j.vaccine.2015.07.051. Epub 2015 Jul 29.

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