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Items: 1 to 50 of 445

1.

Does Structured Exercise Improve Cognitive Impairment in People with Mild to Moderate Dementia? A Cost-Effectiveness Analysis from a Confirmatory Randomised Controlled Trial: The Dementia and Physical Activity (DAPA) Trial.

Khan I, Petrou S, Khan K, Mistry D, Lall R, Sheehan B, Lamb S; DAPA Trial Group.

Pharmacoecon Open. 2018 Sep 11. doi: 10.1007/s41669-018-0097-9. [Epub ahead of print]

2.

Lack of response to quinidine in KCNT1-related neonatal epilepsy.

Numis AL, Nair U, Datta AN, Sands TT, Oldham MS, Patel A, Li M, Gazina E, Petrou S, Cilio MR.

Epilepsia. 2018 Sep 4. doi: 10.1111/epi.14551. [Epub ahead of print]

PMID:
30182418
3.

Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death.

Richards KL, Milligan CJ, Richardson RJ, Jancovski N, Grunnet M, Jacobson LH, Undheim EAB, Mobli M, Chow CY, Herzig V, Csoti A, Panyi G, Reid CA, King GF, Petrou S.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8077-E8085. doi: 10.1073/pnas.1804764115. Epub 2018 Aug 3.

4.

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study.

May P, Girard S, Harrer M, Bobbili DR, Schubert J, Wolking S, Becker F, Lachance-Touchette P, Meloche C, Gravel M, Niturad CE, Knaus J, De Kovel C, Toliat M, Polvi A, Iacomino M, Guerrero-López R, Baulac S, Marini C, Thiele H, Altmüller J, Jabbari K, Ruppert AK, Jurkowski W, Lal D, Rusconi R, Cestèle S, Terragni B, Coombs ID, Reid CA, Striano P, Caglayan H, Siren A, Everett K, Møller RS, Hjalgrim H, Muhle H, Helbig I, Kunz WS, Weber YG, Weckhuysen S, Jonghe P, Sisodiya SM, Nabbout R, Franceschetti S, Coppola A, Vari MS, Kasteleijn-Nolst Trenité D, Baykan B, Ozbek U, Bebek N, Klein KM, Rosenow F, Nguyen DK, Dubeau F, Carmant L, Lortie A, Desbiens R, Clément JF, Cieuta-Walti C, Sills GJ, Auce P, Francis B, Johnson MR, Marson AG, Berghuis B, Sander JW, Avbersek A, McCormack M, Cavalleri GL, Delanty N, Depondt C, Krenn M, Zimprich F, Peter S, Nikanorova M, Kraaij R, van Rooij J, Balling R, Ikram MA, Uitterlinden AG, Avanzini G, Schorge S, Petrou S, Mantegazza M, Sander T, LeGuern E, Serratosa JM, Koeleman BPC, Palotie A, Lehesjoki AE, Nothnagel M, Nürnberg P, Maljevic S, Zara F, Cossette P, Krause R, Lerche H; Epicure Consortium; EuroEPINOMICS CoGIE Consortium; EpiPGX Consortium.

Lancet Neurol. 2018 Aug;17(8):699-708. doi: 10.1016/S1474-4422(18)30215-1. Epub 2018 Jul 17.

PMID:
30033060
5.

Neurons Specifically Activated by Fear Learning in Lateral Amygdala Display Increased Synaptic Strength.

Butler CW, Wilson YM, Oyrer J, Karle TJ, Petrou S, Gunnersen JM, Murphy M, Reid CA.

eNeuro. 2018 Jul 4;5(3). pii: ENEURO.0114-18.2018. doi: 10.1523/ENEURO.0114-18.2018. eCollection 2018 May-Jun.

6.

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest.

Perkins GD, Ji C, Deakin CD, Quinn T, Nolan JP, Scomparin C, Regan S, Long J, Slowther A, Pocock H, Black JJM, Moore F, Fothergill RT, Rees N, O'Shea L, Docherty M, Gunson I, Han K, Charlton K, Finn J, Petrou S, Stallard N, Gates S, Lall R; PARAMEDIC2 Collaborators.

N Engl J Med. 2018 Aug 23;379(8):711-721. doi: 10.1056/NEJMoa1806842. Epub 2018 Jul 18.

PMID:
30021076
7.

Is there an association between early weight status and utility-based health-related quality of life in young children?

Tan EJ, Brown V, Petrou S, D'Souza M, Moodie ML, Wen LM, Baur LA, Rissel C, Hayes AJ.

Qual Life Res. 2018 Jul 10. doi: 10.1007/s11136-018-1932-2. [Epub ahead of print]

PMID:
29992501
8.

Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM).

Norman JE, Marlow N, Messow CM, Shennan A, Bennett PR, Thornton S, Robson SC, McConnachie A, Petrou S, Sebire NJ, Lavender T, Whyte S, Norrie J.

Health Technol Assess. 2018 Jun;22(35):1-304. doi: 10.3310/hta22350.

9.

Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial.

Costa ML, Achten J, Bruce J, Tutton E, Petrou S, Lamb SE, Parsons NR; UK WOLLF Collaboration.

JAMA. 2018 Jun 12;319(22):2280-2288. doi: 10.1001/jama.2018.6452.

PMID:
29896626
10.

Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial.

Griffin DR, Dickenson EJ, Wall PDH, Achana F, Donovan JL, Griffin J, Hobson R, Hutchinson CE, Jepson M, Parsons NR, Petrou S, Realpe A, Smith J, Foster NE; FASHIoN Study Group.

Lancet. 2018 Jun 2;391(10136):2225-2235. doi: 10.1016/S0140-6736(18)31202-9. Epub 2018 Jun 1.

11.

Protocol of a randomised controlled trial of real-time continuous glucose monitoring in neonatal intensive care 'REACT'.

Beardsall K, Thomson L, Guy C, van Weissenbruch MM, Iglesias I, Muthukumar P, Somisetty SK, Bond S, Petrou S, Dunger D; REACT Investigators.

BMJ Open. 2018 Jun 4;8(6):e020816. doi: 10.1136/bmjopen-2017-020816.

12.

Aerobic and strength training exercise programme for cognitive impairment in people with mild to moderate dementia: the DAPA RCT.

Lamb SE, Mistry D, Alleyne S, Atherton N, Brown D, Copsey B, Dosanjh S, Finnegan S, Fordham B, Griffiths F, Hennings S, Khan I, Khan K, Lall R, Lyle S, Nichols V, Petrou S, Zeh P, Sheehan B.

Health Technol Assess. 2018 May;22(28):1-202. doi: 10.3310/hta22280.

13.

Dynamic action potential clamp predicts functional separation in mild familial and severe de novo forms of SCN2A epilepsy.

Berecki G, Howell KB, Deerasooriya YH, Cilio MR, Oliva MK, Kaplan D, Scheffer IE, Berkovic SF, Petrou S.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5516-E5525. doi: 10.1073/pnas.1800077115. Epub 2018 May 29.

PMID:
29844171
14.

Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT.

Costa ML, Achten J, Hennings S, Boota N, Griffin J, Petrou S, Maredza M, Dritsaki M, Wood T, Masters J, Pallister I, Lamb SE, Parsons NR.

Health Technol Assess. 2018 May;22(25):1-148. doi: 10.3310/hta22250.

15.

Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial.

Lamb SE, Sheehan B, Atherton N, Nichols V, Collins H, Mistry D, Dosanjh S, Slowther AM, Khan I, Petrou S, Lall R; DAPA Trial Investigators.

BMJ. 2018 May 16;361:k1675. doi: 10.1136/bmj.k1675.

16.

A Practical Guide to Conducting a Systematic Review and Meta-analysis of Health State Utility Values.

Petrou S, Kwon J, Madan J.

Pharmacoeconomics. 2018 May 10. doi: 10.1007/s40273-018-0670-1. [Epub ahead of print]

PMID:
29750430
17.

Comparison of an Oral Factor Xa Inhibitor With Low Molecular Weight Heparin in Patients With Cancer With Venous Thromboembolism: Results of a Randomized Trial (SELECT-D).

Young AM, Marshall A, Thirlwall J, Chapman O, Lokare A, Hill C, Hale D, Dunn JA, Lyman GH, Hutchinson C, MacCallum P, Kakkar A, Hobbs FDR, Petrou S, Dale J, Poole CJ, Maraveyas A, Levine M.

J Clin Oncol. 2018 Jul 10;36(20):2017-2023. doi: 10.1200/JCO.2018.78.8034. Epub 2018 May 10.

PMID:
29746227
18.

Infographic: Economic justification for intramedullary nail fixation over locking plate fixation for extra-articular distal tibial fractures.

Maredza M, Petrou S, Dritsaki M, Achten J, Griffin J, Lamb SE, Parsons NR, Costa ML.

Bone Joint J. 2018 May 1;100-B(5):622-623. doi: 10.1302/0301-620X.100B5.BJJ-2017-0393. No abstract available.

PMID:
29701095
19.

A comparison of the cost-effectiveness of intramedullary nail fixation and locking plate fixation in the treatment of adult patients with an extra-articular fracture of the distal tibia.

Maredza M, Petrou S, Dritsaki M, Achten J, Griffin J, Lamb SE, Parsons NR, Costa ML.

Bone Joint J. 2018 May 1;100-B(5):624-633. doi: 10.1302/0301-620X.100B5.BJJ-2017-1329.R2.

PMID:
29701091
20.

Progress in Understanding and Treating SCN2A-Mediated Disorders.

Sanders SJ, Campbell AJ, Cottrell JR, Moller RS, Wagner FF, Auldridge AL, Bernier RA, Catterall WA, Chung WK, Empfield JR, George AL Jr, Hipp JF, Khwaja O, Kiskinis E, Lal D, Malhotra D, Millichap JJ, Otis TS, Petrou S, Pitt G, Schust LF, Taylor CM, Tjernagel J, Spiro JE, Bender KJ.

Trends Neurosci. 2018 Jul;41(7):442-456. doi: 10.1016/j.tins.2018.03.011. Epub 2018 Apr 23. Review.

PMID:
29691040
21.

Can mutation-mediated effects occurring early in development cause long-term seizure susceptibility in genetic generalized epilepsies?

Reid CA, Rollo B, Petrou S, Berkovic SF.

Epilepsia. 2018 May;59(5):915-922. doi: 10.1111/epi.14077. Epub 2018 Apr 16.

PMID:
29658992
22.

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.

Anderson DJ, Kaplan DI, Bell KM, Koutsis K, Haynes JM, Mills RJ, Phelan DG, Qian EL, Leitoguinho AR, Arasaratnam D, Labonne T, Ng ES, Davis RP, Casini S, Passier R, Hudson JE, Porrello ER, Costa MW, Rafii A, Curl CL, Delbridge LM, Harvey RP, Oshlack A, Cheung MM, Mummery CL, Petrou S, Elefanty AG, Stanley EG, Elliott DA.

Nat Commun. 2018 Apr 10;9(1):1373. doi: 10.1038/s41467-018-03714-x.

23.

The coma in glaucoma: Retinal ganglion cell dysfunction and recovery.

Fry LE, Fahy E, Chrysostomou V, Hui F, Tang J, van Wijngaarden P, Petrou S, Crowston JG.

Prog Retin Eye Res. 2018 Jul;65:77-92. doi: 10.1016/j.preteyeres.2018.04.001. Epub 2018 Apr 6. Review.

PMID:
29631042
24.

Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy.

Becker F, Reid CA, Hallmann K, Tae HS, Phillips AM, Teodorescu G, Weber YG, Kleefuss-Lie A, Elger C, Perez-Reyes E, Petrou S, Kunz WS, Lerche H, Maljevic S.

Epilepsia Open. 2017 Aug 5;2(3):334-342. doi: 10.1002/epi4.12068. eCollection 2017 Sep.

25.

A comprehensive approach to identifying repurposed drugs to treat SCN8A epilepsy.

Atkin TA, Maher CM, Gerlach AC, Gay BC, Antonio BM, Santos SC, Padilla KM, Rader J, Krafte DS, Fox MA, Stewart GR, Petrovski S, Devinsky O, Might M, Petrou S, Goldstein DB.

Epilepsia. 2018 Apr;59(4):802-813. doi: 10.1111/epi.14037. Epub 2018 Mar 25.

PMID:
29574705
26.

Randomised controlled trial of exercise to prevent shoulder problems in women undergoing breast cancer treatment: study protocol for the prevention of shoulder problems trial (UK PROSPER).

Bruce J, Williamson E, Lait C, Richmond H, Betteley L, Lall R, Petrou S, Rees S, Withers EJ, Lamb SE, Thompson AM; PROSPER Study Group.

BMJ Open. 2018 Mar 23;8(3):e019078. doi: 10.1136/bmjopen-2017-019078.

27.

Economic costs and health-related quality of life outcomes of hospitalised patients with high HIV prevalence: A prospective hospital cohort study in Malawi.

Maheswaran H, Petrou S, Cohen D, MacPherson P, Kumwenda F, Lalloo DG, Corbett EL, Clarke A.

PLoS One. 2018 Mar 15;13(3):e0192991. doi: 10.1371/journal.pone.0192991. eCollection 2018.

28.

Outcomes assessment of hepatitis C virus-positive psoriatic patients treated using pegylated interferon in combination with ribavirin compared to new Direct-Acting Antiviral agents.

Damiani G, Franchi C, Pigatto P, Altomare A, Pacifico A, Petrou S, Leone S, Pace MC, Fiore M.

World J Hepatol. 2018 Feb 27;10(2):329-336. doi: 10.4254/wjh.v10.i2.329.

29.

Epidemiological trends and risk factors for tobacco, alcohol and drug use among adolescents in Scotland, 2002-13.

Petrou S, Kupek E.

J Public Health (Oxf). 2018 Feb 2. doi: 10.1093/pubmed/fdy006. [Epub ahead of print]

PMID:
29409021
30.

Estimating the health-care costs of children born to pregnant smokers in England: cohort study using primary and secondary health-care data.

Vaz LR, Jones MJ, Szatkowski L, Tata LJ, Petrou S, Coleman T.

Addiction. 2018 Jul;113(7):1305-1316. doi: 10.1111/add.14183. Epub 2018 Mar 2.

31.

Authors' reply re: Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data.

Achana F, Fleming K, Tata LJ, Sultan AA, Petrou S.

BJOG. 2018 Jun;125(7):906-907. doi: 10.1111/1471-0528.15104. Epub 2018 Jan 23. No abstract available.

PMID:
29359474
32.

Utility values for childhood obesity interventions: a systematic review and meta-analysis of the evidence for use in economic evaluation.

Brown V, Tan EJ, Hayes AJ, Petrou S, Moodie ML.

Obes Rev. 2018 Jul;19(7):905-916. doi: 10.1111/obr.12672. Epub 2018 Jan 21. Review.

PMID:
29356315
33.

Wide variation in severe neonatal morbidity among very preterm infants in European regions.

Edstedt Bonamy AK, Zeitlin J, Piedvache A, Maier RF, van Heijst A, Varendi H, Manktelow BN, Fenton A, Mazela J, Cuttini M, Norman M, Petrou S, Reempts PV, Barros H, Draper ES; Epice Research Group.

Arch Dis Child Fetal Neonatal Ed. 2018 Jan 20. pii: fetalneonatal-2017-313697. doi: 10.1136/archdischild-2017-313697. [Epub ahead of print]

PMID:
29353260
34.

Expensive care? Resource-based thresholds for potentially inappropriate treatment in intensive care.

Wilkinson D, Petrou S, Savulescu J.

Monash Bioeth Rev. 2018 Jul;35(1-4):2-23. doi: 10.1007/s40592-017-0075-5.

35.

A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY.

Scott DJ, Gunn NJ, Yong KJ, Wimmer VC, Veldhuis NA, Challis LM, Haidar M, Petrou S, Bathgate RAD, Griffin MDW.

Sci Rep. 2018 Jan 12;8(1):667. doi: 10.1038/s41598-017-18045-y.

36.

Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy.

Pederick DT, Richards KL, Piltz SG, Kumar R, Mincheva-Tasheva S, Mandelstam SA, Dale RC, Scheffer IE, Gecz J, Petrou S, Hughes JN, Thomas PQ.

Neuron. 2018 Jan 3;97(1):59-66.e5. doi: 10.1016/j.neuron.2017.12.005.

PMID:
29301106
37.

Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies.

Oyrer J, Maljevic S, Scheffer IE, Berkovic SF, Petrou S, Reid CA.

Pharmacol Rev. 2018 Jan;70(1):142-173. doi: 10.1124/pr.117.014456. Review.

PMID:
29263209
38.

Current UK Practices on Health Economics Analysis Plans (HEAPs): Are We Using Heaps of Them?

Dritsaki M, Gray A, Petrou S, Dutton S, Lamb SE, Thorn JC.

Pharmacoeconomics. 2018 Feb;36(2):253-257. doi: 10.1007/s40273-017-0598-x. No abstract available.

PMID:
29214388
39.

Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy.

McTague A, Nair U, Malhotra S, Meyer E, Trump N, Gazina EV, Papandreou A, Ngoh A, Ackermann S, Ambegaonkar G, Appleton R, Desurkar A, Eltze C, Kneen R, Kumar AV, Lascelles K, Montgomery T, Ramesh V, Samanta R, Scott RH, Tan J, Whitehouse W, Poduri A, Scheffer IE, Chong WKK, Cross JH, Topf M, Petrou S, Kurian MA.

Neurology. 2018 Jan 2;90(1):e55-e66. doi: 10.1212/WNL.0000000000004762. Epub 2017 Dec 1.

40.

Precision therapy for epilepsy due to KCNT1 mutations: A randomized trial of oral quinidine.

Mullen SA, Carney PW, Roten A, Ching M, Lightfoot PA, Churilov L, Nair U, Li M, Berkovic SF, Petrou S, Scheffer IE.

Neurology. 2018 Jan 2;90(1):e67-e72. doi: 10.1212/WNL.0000000000004769. Epub 2017 Dec 1.

PMID:
29196578
41.

Results of the First Steps study: a randomised controlled trial and economic evaluation of the Group Family Nurse Partnership (gFNP) programme compared with usual care in improving outcomes for high-risk mothers and their children and preventing abuse.

Barnes J, Stuart J, Allen E, Petrou S, Sturgess J, Barlow J, Macdonald G, Spiby H, Aistrop D, Melhuish E, Kim S, Pink J, Datta J, Elbourne D.

Southampton (UK): NIHR Journals Library; 2017 Nov.

42.

Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Trial.

Costa ML, Achten J, Griffin J, Petrou S, Pallister I, Lamb SE, Parsons NR; FixDT Trial Investigators.

JAMA. 2017 Nov 14;318(18):1767-1776. doi: 10.1001/jama.2017.16429.

43.

Cost-Effectiveness of Community-based Human Immunodeficiency Virus Self-Testing in Blantyre, Malawi.

Maheswaran H, Clarke A, MacPherson P, Kumwenda F, Lalloo DG, Corbett EL, Petrou S.

Clin Infect Dis. 2018 Apr 3;66(8):1211-1221. doi: 10.1093/cid/cix983.

44.

Non-Neurotoxic Nanodiamond Probes for Intraneuronal Temperature Mapping.

Simpson DA, Morrisroe E, McCoey JM, Lombard AH, Mendis DC, Treussart F, Hall LT, Petrou S, Hollenberg LCL.

ACS Nano. 2017 Dec 26;11(12):12077-12086. doi: 10.1021/acsnano.7b04850. Epub 2017 Nov 13.

PMID:
29111670
45.

An Organization Model to Assist Individual Physicians, Scientists, and Senior Health Care Administrators With Personal and Professional Needs.

Shanafelt TD, Lightner DJ, Conley CR, Petrou SP, Richardson JW, Schroeder PJ, Brown WA.

Mayo Clin Proc. 2017 Nov;92(11):1688-1696. doi: 10.1016/j.mayocp.2017.08.020. Epub 2017 Nov 1. Review.

PMID:
29101937
46.

Rationing potentially inappropriate treatment in newborn intensive care in developed countries.

Wilkinson D, Petrou S, Savulescu J.

Semin Fetal Neonatal Med. 2018 Feb;23(1):52-58. doi: 10.1016/j.siny.2017.10.004. Epub 2017 Oct 31. Review.

PMID:
29100870
47.

Randomized controlled trial and economic evaluation of nurse-led group support for young mothers during pregnancy and the first year postpartum versus usual care.

Barnes J, Stuart J, Allen E, Petrou S, Sturgess J, Barlow J, Macdonald G, Spiby H, Aistrop D, Melhuish E, Kim SW, Elbourne D.

Trials. 2017 Nov 1;18(1):508. doi: 10.1186/s13063-017-2259-y.

48.

Cast versus functional brace in the rehabilitation of patients treated non-operatively for a rupture of the Achilles tendon: protocol for the UK study of tendo achilles rehabilitation (UK STAR) multi-centre randomised trial.

Achten J, Parsons NR, Kearney RL, Maia Schlüssel M, Liew AS, Dutton S, Petrou S, Ollivere B, Lamb SE, Costa ML.

BMJ Open. 2017 Oct 24;7(10):e019628. doi: 10.1136/bmjopen-2017-019628.

49.

Gain-of-function HCN2 variants in genetic epilepsy.

Li M, Maljevic S, Phillips AM, Petrovski S, Hildebrand MS, Burgess R, Mount T, Zara F, Striano P, Schubert J, Thiele H, Nürnberg P, Wong M, Weisenberg JL, Thio LL, Lerche H, Scheffer IE, Berkovic SF, Petrou S, Reid CA.

Hum Mutat. 2018 Feb;39(2):202-209. doi: 10.1002/humu.23357. Epub 2017 Nov 13.

PMID:
29064616
50.

A Systematic Review and Meta-analysis of Childhood Health Utilities.

Kwon J, Kim SW, Ungar WJ, Tsiplova K, Madan J, Petrou S.

Med Decis Making. 2018 Apr;38(3):277-305. doi: 10.1177/0272989X17732990. Epub 2017 Oct 7.

PMID:
28990449

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