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Items: 9


Reproducing human and cross-species drug toxicities using a Liver-Chip.

Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA.

Sci Transl Med. 2019 Nov 6;11(517). pii: eaax5516. doi: 10.1126/scitranslmed.aax5516.


Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.

Foster AJ, Chouhan B, Regan SL, Rollison H, Amberntsson S, Andersson LC, Srivastava A, Darnell M, Cairns J, Lazic SE, Jang KJ, Petropolis DB, Kodella K, Rubins JE, Williams D, Hamilton GA, Ewart L, Morgan P.

Arch Toxicol. 2019 Apr;93(4):1021-1037. doi: 10.1007/s00204-019-02427-4. Epub 2019 Mar 26.


Introducing an automated high content confocal imaging approach for Organs-on-Chips.

Peel S, Corrigan AM, Ehrhardt B, Jang KJ, Caetano-Pinto P, Boeckeler M, Rubins JE, Kodella K, Petropolis DB, Ronxhi J, Kulkarni G, Foster AJ, Williams D, Hamilton GA, Ewart L.

Lab Chip. 2019 Jan 29;19(3):410-421. doi: 10.1039/c8lc00829a.


Human Liver Infection in a Dish: Easy-To-Build 3D Liver Models for Studying Microbial Infection.

Petropolis DB, Faust DM, Tolle M, Rivière L, Valentin T, Neuveut C, Hernandez-Cuevas N, Dufour A, Olivo-Marin JC, Guillen N.

PLoS One. 2016 Feb 10;11(2):e0148667. doi: 10.1371/journal.pone.0148667. eCollection 2016.


A new human 3D-liver model unravels the role of galectins in liver infection by the parasite Entamoeba histolytica.

Petropolis DB, Faust DM, Deep Jhingan G, Guillen N.

PLoS Pathog. 2014 Sep 11;10(9):e1004381. doi: 10.1371/journal.ppat.1004381. eCollection 2014 Sep.


Leishmania amazonensis promastigotes in 3D Collagen I culture: an in vitro physiological environment for the study of extracellular matrix and host cell interactions.

Petropolis DB, Rodrigues JC, Viana NB, Pontes B, Pereira CF, Silva-Filho FC.

PeerJ. 2014 Apr 3;2:e317. doi: 10.7717/peerj.317. eCollection 2014.


The redox potential interferes with the expression of laminin binding molecules in Bacteroides fragilis.

Ferreira Ede O, Yates EA, Goldner M, Vommaro RC, Silva Filho FC, Petrópolis DB, Domingues RM.

Mem Inst Oswaldo Cruz. 2008 Nov;103(7):683-9.


The binding of Tritrichomonas foetus to immobilized laminin-1 and its role in the cytotoxicity exerted by the parasite.

Petrópolis DB, Fernandes Rodrigues JC, da Rocha-Azevedo B, Costa e Silva-Filho F.

Microbiology. 2008 Aug;154(Pt 8):2283-90. doi: 10.1099/mic.0.2007/015941-0.


How laminin-1 can be recognized by the protozoan parasite Tritrichomonas foetus: possible role played by the extracellular matrix glycoprotein in both cytoadhesion and cytotoxicity exerted by the parasite.

Silva-Filho FC, Kasai S, Nomizu M, López LB, Melo-Braga MB, Rocha-Azevedo B, Petrópolis DB, Horbach IS.

Parasitol Int. 2002 Sep;51(3):305-7. Review.


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