Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 116

1.

Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.

Van Steenwinckel J, Schang AL, Krishnan ML, Degos V, Delahaye-Duriez A, Bokobza C, Csaba Z, Verdonk F, Montané A, Sigaut S, Hennebert O, Lebon S, Schwendimann L, Le Charpentier T, Hassan-Abdi R, Ball G, Aljabar P, Saxena A, Holloway RK, Birchmeier W, Baud O, Rowitch D, Miron V, Chretien F, Leconte C, Besson VC, Petretto EG, Edwards AD, Hagberg H, Soussi-Yanicostas N, Fleiss B, Gressens P.

Brain. 2019 Oct 30. pii: awz319. doi: 10.1093/brain/awz319. [Epub ahead of print]

PMID:
31665242
2.

Transcriptional Networks of Microglia in Alzheimer's Disease and Insights into Pathogenesis.

Chew G, Petretto E.

Genes (Basel). 2019 Oct 12;10(10). pii: E798. doi: 10.3390/genes10100798. Review.

3.

Broad regulation of gene isoform expression by Wnt signaling in cancer.

Idris M, Harmston N, Petretto EG, Madan B, Virshup DM.

RNA. 2019 Sep 10. pii: rna.071506.119. doi: 10.1261/rna.071506.119. [Epub ahead of print]

PMID:
31506381
4.

Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.

Chen H, Moreno-Moral A, Pesce F, Devapragash N, Mancini M, Heng EL, Rotival M, Srivastava PK, Harmston N, Shkura K, Rackham OJL, Yu WP, Sun XM, Tee NGZ, Tan ELS, Barton PJR, Felkin LE, Lara-Pezzi E, Angelini G, Beltrami C, Pravenec M, Schafer S, Bottolo L, Hubner N, Emanueli C, Cook SA, Petretto E.

Nat Commun. 2019 Sep 9;10(1):4085. doi: 10.1038/s41467-019-12060-5.

5.

Integrated systems-genetic analyses reveal a network target for delaying glioma progression.

Laaniste L, Srivastava PK, Stylianou J, Syed N, Cases-Cunillera S, Shkura K, Zeng Q, Rackham OJL, Langley SR, Delahaye-Duriez A, O'Neill K, Williams M, Becker A, Roncaroli F, Petretto E, Johnson MR.

Ann Clin Transl Neurol. 2019 Sep;6(9):1616-1638. doi: 10.1002/acn3.50850. Epub 2019 Aug 17.

6.

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.

Chen H, Moreno-Moral A, Pesce F, Devapragash N, Mancini M, Heng EL, Rotival M, Srivastava PK, Harmston N, Shkura K, Rackham OJL, Yu WP, Sun XM, Tee NGZ, Tan ELS, Barton PJR, Felkin LE, Lara-Pezzi E, Angelini G, Beltrami C, Pravenec M, Schafer S, Bottolo L, Hubner N, Emanueli C, Cook SA, Petretto E.

Nat Commun. 2019 Aug 9;10(1):3616. doi: 10.1038/s41467-019-11551-9. Erratum in: Nat Commun. 2019 Sep 9;10(1):4085.

7.

miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia.

Besnier M, Shantikumar S, Anwar M, Dixit P, Chamorro-Jorganes A, Sweaad W, Sala-Newby G, Madeddu P, Thomas AC, Howard L, Mushtaq S, Petretto E, Caporali A, Emanueli C.

Mol Ther Nucleic Acids. 2019 Sep 6;17:49-62. doi: 10.1016/j.omtn.2019.05.002. Epub 2019 May 17.

8.

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.

Ferrari Bardile C, Garcia-Miralles M, Caron NS, Rayan NA, Langley SR, Harmston N, Rondelli AM, Teo RTY, Waltl S, Anderson LM, Bae HG, Jung S, Williams A, Prabhakar S, Petretto E, Hayden MR, Pouladi MA.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9622-9627. doi: 10.1073/pnas.1818042116. Epub 2019 Apr 23.

9.

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors.

Yap L, Wang JW, Moreno-Moral A, Chong LY, Sun Y, Harmston N, Wang X, Chong SY, Öhman MK, Wei H, Bunte R, Gosh S, Cook S, Hovatta O, de Kleijn DPV, Petretto E, Tryggvason K.

Cell Rep. 2019 Mar 19;26(12):3231-3245.e9. doi: 10.1016/j.celrep.2019.02.083.

10.

Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance.

Ford KL, Anwar M, Heys R, Ahmed EM, Caputo M, Game L, Reeves BC, Punjabi PP, Angelini GD, Petretto E, Emanueli C.

PLoS One. 2019 Mar 14;14(3):e0213685. doi: 10.1371/journal.pone.0213685. eCollection 2019.

11.

An Atomistic Look into Bio-inspired Nanoparticles and their Molecular Interactions with Cells.

Petretto E, Campomanes P, Stellacci F, Rothen-Rutishauser B, Petri-Fink A, Vanni S.

Chimia (Aarau). 2019 Feb 27;73(1):78-80. doi: 10.2533/chimia.2019.78. Review.

PMID:
30814004
12.

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.

Ooi J, Langley SR, Xu X, Utami KH, Sim B, Huang Y, Harmston NP, Tay YL, Ziaei A, Zeng R, Low D, Aminkeng F, Sobota RM, Ginhoux F, Petretto E, Pouladi MA.

Cell Rep. 2019 Feb 26;26(9):2494-2508.e7. doi: 10.1016/j.celrep.2019.02.008.

13.

Sleeve gastrectomy rapidly enhances islet function independently of body weight.

Douros JD, Niu J, Sdao S, Gregg T, Fisher-Wellman K, Bharadwaj M, Molina A, Arumugam R, Martin M, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell J, D'Alessio D.

JCI Insight. 2019 Mar 21;4(6). pii: 126688. doi: 10.1172/jci.insight.126688. eCollection 2019 Mar 21.

14.

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing.

Bagnati M, Moreno-Moral A, Ko JH, Nicod J, Harmston N, Imprialou M, Game L, Gil J, Petretto E, Behmoaras J.

JCI Insight. 2019 Jan 24;4(2). pii: 125736. doi: 10.1172/jci.insight.125736. [Epub ahead of print]

15.

Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction.

Adriaens ME, Lodder EM, Moreno-Moral A, Šilhavý J, Heinig M, Glinge C, Belterman C, Wolswinkel R, Petretto E, Pravenec M, Remme CA, Bezzina CR.

J Am Heart Assoc. 2018 Nov 6;7(21):e009243. doi: 10.1161/JAHA.118.009243.

16.

Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture.

Tjin MS, Chua AWC, Moreno-Moral A, Chong LY, Tang PY, Harmston NP, Cai Z, Petretto E, Tan BK, Tryggvason K.

Nat Commun. 2018 Oct 30;9(1):4432. doi: 10.1038/s41467-018-06934-3.

17.

Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis.

Madan B, Harmston N, Nallan G, Montoya A, Faull P, Petretto E, Virshup DM.

J Clin Invest. 2018 Dec 3;128(12):5620-5633. doi: 10.1172/JCI122383. Epub 2018 Nov 12.

18.

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.

Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR.

Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4.

19.

Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.

Tan ALM, Langley SR, Tan CF, Chai JF, Khoo CM, Leow MK, Khoo EYH, Moreno-Moral A, Pravenec M, Rotival M, Sadananthan SA, Velan SS, Venkataraman K, Chong YS, Lee YS, Sim X, Stunkel W, Liu MH, Tai ES, Petretto E.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):465-486. doi: 10.1210/jc.2018-00309.

PMID:
30137523
20.

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.

Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M.

Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20.

21.

Universal effects of solvent species on the stabilized structure of a protein.

Hayashi T, Inoue M, Yasuda S, Petretto E, Škrbić T, Giacometti A, Kinoshita M.

J Chem Phys. 2018 Jul 28;149(4):045105. doi: 10.1063/1.5042111.

PMID:
30068177
22.

Common signalling pathways in macrophage and osteoclast multinucleation.

Pereira M, Petretto E, Gordon S, Bassett JHD, Williams GR, Behmoaras J.

J Cell Sci. 2018 Jun 5;131(11). pii: jcs216267. doi: 10.1242/jcs.216267. Review.

23.

Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.

Olona A, Terra X, Ko JH, Grau-Bové C, Pinent M, Ardevol A, Diaz AG, Moreno-Moral A, Edin M, Bishop-Bailey D, Zeldin DC, Aitman TJ, Petretto E, Blay M, Behmoaras J.

Mol Metab. 2018 May;11:18-32. doi: 10.1016/j.molmet.2018.03.003. Epub 2018 Mar 9.

24.

Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice.

Sigmundsson K, Ojala JRM, Öhman MK, Österholm AM, Moreno-Moral A, Domogatskaya A, Chong LY, Sun Y, Chai X, Steele JAM, George B, Patarroyo M, Nilsson AS, Rodin S, Ghosh S, Stevens MM, Petretto E, Tryggvason K.

Matrix Biol. 2018 Sep;70:5-19. doi: 10.1016/j.matbio.2018.03.018. Epub 2018 Mar 27.

25.

Response to: 'M-CSF and GM-CSF monocyte-derived macrophages in systemic sclerosis: the two sides of the same coin?' by Lescoat et al.

Behmoaras J, Petretto E.

Ann Rheum Dis. 2019 Mar;78(3):e20. doi: 10.1136/annrheumdis-2018-213121. Epub 2018 Mar 9. No abstract available.

26.

Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk.

Moreno-Moral A, Bagnati M, Koturan S, Ko JH, Fonseca C, Harmston N, Game L, Martin J, Ong V, Abraham DJ, Denton CP, Behmoaras J, Petretto E.

Ann Rheum Dis. 2018 Apr;77(4):596-601. doi: 10.1136/annrheumdis-2017-212454. Epub 2018 Jan 17.

27.

Meta-Analysis of MicroRNAs Dysregulated in the Hippocampal Dentate Gyrus of Animal Models of Epilepsy.

Srivastava PK, Roncon P, Lukasiuk K, Gorter JA, Aronica E, Pitkänen A, Petretto E, Johnson MR, Simonato M.

eNeuro. 2017 Dec 28;4(6). pii: ENEURO.0152-17.2017. doi: 10.1523/ENEURO.0152-17.2017. eCollection 2017 Nov-Dec.

28.

Cell Type of Origin Dictates the Route to Pluripotency.

Nefzger CM, Rossello FJ, Chen J, Liu X, Knaupp AS, Firas J, Paynter JM, Pflueger J, Buckberry S, Lim SM, Williams B, Alaei S, Faye-Chauhan K, Petretto E, Nilsson SK, Lister R, Ramialison M, Powell DR, Rackham OJL, Polo JM.

Cell Rep. 2017 Dec 5;21(10):2649-2660. doi: 10.1016/j.celrep.2017.11.029.

29.

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.

Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P.

Diabetologia. 2018 Mar;61(3):641-657. doi: 10.1007/s00125-017-4500-3. Epub 2017 Nov 28.

30.

IL-11 is a crucial determinant of cardiovascular fibrosis.

Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimarães-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA.

Nature. 2017 Dec 7;552(7683):110-115. doi: 10.1038/nature24676. Epub 2017 Nov 13.

31.

MWASTools: an R/bioconductor package for metabolome-wide association studies.

Rodriguez-Martinez A, Posma JM, Ayala R, Neves AL, Anwar M, Petretto E, Emanueli C, Gauguier D, Nicholson JK, Dumas ME.

Bioinformatics. 2018 Mar 1;34(5):890-892. doi: 10.1093/bioinformatics/btx477.

32.

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.

Heinig M, Adriaens ME, Schafer S, van Deutekom HWM, Lodder EM, Ware JS, Schneider V, Felkin LE, Creemers EE, Meder B, Katus HA, Rühle F, Stoll M, Cambien F, Villard E, Charron P, Varro A, Bishopric NH, George AL Jr, Dos Remedios C, Moreno-Moral A, Pesce F, Bauerfeind A, Rüschendorf F, Rintisch C, Petretto E, Barton PJ, Cook SA, Pinto YM, Bezzina CR, Hubner N.

Genome Biol. 2017 Sep 14;18(1):170. doi: 10.1186/s13059-017-1286-z.

33.

An embryonic system to assess direct and indirect Wnt transcriptional targets.

Suresh J, Harmston N, Lim KK, Kaur P, Jin HJ, Lusk JB, Petretto E, Tolwinski NS.

Sci Rep. 2017 Sep 11;7(1):11092. doi: 10.1038/s41598-017-11519-z.

34.

Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants.

Krishnan ML, Van Steenwinckel J, Schang AL, Yan J, Arnadottir J, Le Charpentier T, Csaba Z, Dournaud P, Cipriani S, Auvynet C, Titomanlio L, Pansiot J, Ball G, Boardman JP, Walley AJ, Saxena A, Mirza G, Fleiss B, Edwards AD, Petretto E, Gressens P.

Nat Commun. 2017 Sep 5;8(1):428. doi: 10.1038/s41467-017-00422-w.

35.

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.

Chen TD, Rotival M, Chiu LY, Bagnati M, Ko JH, Srivastava PK, Petretto E, Pusey CD, Lai PC, Aitman TJ, Cook HT, Behmoaras J.

Genetics. 2017 Jun;206(2):1139-1151. doi: 10.1534/genetics.116.197376. Epub 2017 Apr 26.

36.

Genome-wide analysis of differential RNA editing in epilepsy.

Srivastava PK, Bagnati M, Delahaye-Duriez A, Ko JH, Rotival M, Langley SR, Shkura K, Mazzuferi M, Danis B, van Eyll J, Foerch P, Behmoaras J, Kaminski RM, Petretto E, Johnson MR.

Genome Res. 2017 Mar;27(3):440-450. doi: 10.1101/gr.210740.116.

37.

A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation.

Rackham OJ, Langley SR, Oates T, Vradi E, Harmston N, Srivastava PK, Behmoaras J, Dellaportas P, Bottolo L, Petretto E.

Genetics. 2017 Apr;205(4):1443-1458. doi: 10.1534/genetics.116.195008. Epub 2017 Feb 17.

38.

Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis.

Beltrami C, Besnier M, Shantikumar S, Shearn AI, Rajakaruna C, Laftah A, Sessa F, Spinetti G, Petretto E, Angelini GD, Emanueli C.

Mol Ther. 2017 Mar 1;25(3):679-693. doi: 10.1016/j.ymthe.2016.12.022. Epub 2017 Feb 1.

39.

Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.

McDermott-Roe C, Leleu M, Rowe GC, Palygin O, Bukowy JD, Kuo J, Rech M, Hermans-Beijnsberger S, Schaefer S, Adami E, Creemers EE, Heinig M, Schroen B, Arany Z, Petretto E, Geurts AM.

PLoS One. 2017 Feb 3;12(2):e0170458. doi: 10.1371/journal.pone.0170458. eCollection 2017.

40.

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat.

Coan PM, Hummel O, Garcia Diaz A, Barrier M, Alfazema N, Norsworthy PJ, Pravenec M, Petretto E, Hübner N, Aitman TJ.

Dis Model Mech. 2017 Mar 1;10(3):297-306. doi: 10.1242/dmm.026716. Epub 2017 Jan 26.

41.

The State of Systems Genetics in 2017.

Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, Steinmetz LM, Vonesch SC.

Cell Syst. 2017 Jan 25;4(1):7-15. doi: 10.1016/j.cels.2017.01.005.

42.

Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery.

Delahaye-Duriez A, Srivastava P, Shkura K, Langley SR, Laaniste L, Moreno-Moral A, Danis B, Mazzuferi M, Foerch P, Gazina EV, Richards K, Petrou S, Kaminski RM, Petretto E, Johnson MR.

Genome Biol. 2016 Dec 13;17(1):245.

43.

Systems Genetics as a Tool to Identify Master Genetic Regulators in Complex Disease.

Moreno-Moral A, Pesce F, Behmoaras J, Petretto E.

Methods Mol Biol. 2017;1488:337-362.

PMID:
27933533
44.

Expression QTLs Mapping and Analysis: A Bayesian Perspective.

Imprialou M, Petretto E, Bottolo L.

Methods Mol Biol. 2017;1488:189-215. Review.

PMID:
27933525
45.

Influence of shear stress magnitude and direction on atherosclerotic plaque composition.

Pedrigi RM, Mehta VV, Bovens SM, Mohri Z, Poulsen CB, Gsell W, Tremoleda JL, Towhidi L, de Silva R, Petretto E, Krams R.

R Soc Open Sci. 2016 Oct 19;3(10):160588. eCollection 2016 Oct.

46.

Computational methods for direct cell conversion.

Kamaraj US, Gough J, Polo JM, Petretto E, Rackham OJ.

Cell Cycle. 2016 Dec 16;15(24):3343-3354. doi: 10.1080/15384101.2016.1238119. Epub 2016 Oct 13. Review.

47.

From integrative genomics to systems genetics in the rat to link genotypes to phenotypes.

Moreno-Moral A, Petretto E.

Dis Model Mech. 2016 Oct 1;9(10):1097-1110. Review.

48.

Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet.

Martínez-Micaelo N, González-Abuín N, Terra X, Ardévol A, Pinent M, Petretto E, Behmoaras J, Blay M.

Dis Model Mech. 2016 Oct 1;9(10):1231-1239. Epub 2016 Jul 13.

49.

Wars2 is a determinant of angiogenesis.

Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, Widjaja AA, Schafer S, Yusoff P, Choksi PK, Ko NS, Singh MK, Epstein D, Guan Y, Houštěk J, Mracek T, Nuskova H, Mikell B, Tan J, Pesce F, Kolar F, Bottolo L, Mancini M, Hubner N, Pravenec M, Petretto E, MacRae C, Cook SA.

Nat Commun. 2016 Jul 8;7:12061. doi: 10.1038/ncomms12061.

50.

A predictive computational framework for direct reprogramming between human cell types.

Rackham OJ, Firas J, Fang H, Oates ME, Holmes ML, Knaupp AS; FANTOM Consortium, Suzuki H, Nefzger CM, Daub CO, Shin JW, Petretto E, Forrest AR, Hayashizaki Y, Polo JM, Gough J.

Nat Genet. 2016 Mar;48(3):331-5. doi: 10.1038/ng.3487. Epub 2016 Jan 18.

PMID:
26780608

Supplemental Content

Loading ...
Support Center