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Items: 13


Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals.

Hawkins JL, Robbins MD, Warren LC, Xia D, Petras SF, Valentine JJ, Varghese AH, Wang IK, Subashi TA, Shelly LD, Hay BA, Landschulz KT, Geoghegan KF, Harwood HJ Jr.

J Pharmacol Exp Ther. 2008 Sep;326(3):801-8. doi: 10.1124/jpet.108.139626. Epub 2008 Jun 24.


Aminopyrrolidineamide inhibitors of site-1 protease.

Hay BA, Abrams B, Zumbrunn AY, Valentine JJ, Warren LC, Petras SF, Shelly LD, Xia A, Varghese AH, Hawkins JL, Van Camp JA, Robbins MD, Landschulz K, Harwood HJ Jr.

Bioorg Med Chem Lett. 2007 Aug 15;17(16):4411-4. Epub 2007 Jun 10.


Regulation of osteoclast differentiation by statins.

Grasser WA, Baumann AP, Petras SF, Harwood HJ Jr, Devalaraja R, Renkiewicz R, Baragi V, Thompson DD, Paraklar VM.

J Musculoskelet Neuronal Interact. 2003 Mar;3(1):53-62.


Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.

Harwood HJ Jr, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL.

J Lipid Res. 2005 Mar;46(3):547-63. Epub 2004 Dec 16.


Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals.

Harwood HJ Jr, Petras SF, Shelly LD, Zaccaro LM, Perry DA, Makowski MR, Hargrove DM, Martin KA, Tracey WR, Chapman JG, Magee WP, Dalvie DK, Soliman VF, Martin WH, Mularski CJ, Eisenbeis SA.

J Biol Chem. 2003 Sep 26;278(39):37099-111. Epub 2003 Jul 3.


CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans.

Chandler CE, Wilder DE, Pettini JL, Savoy YE, Petras SF, Chang G, Vincent J, Harwood HJ Jr.

J Lipid Res. 2003 Oct;44(10):1887-901. Epub 2003 Jul 1.


Antigenic and virulence properties of Pasteurella haemolytica leukotoxin mutants.

Petras SF, Chidambaram M, Illyes EF, Froshauer S, Weinstock GM, Reese CP.

Infect Immun. 1995 Mar;63(3):1033-9.


Isolation of Pasteurella haemolytica leukotoxin mutants.

Chidambaram M, Sharma B, Petras SF, Reese CP, Froshauer S, Weinstock GM.

Infect Immun. 1995 Mar;63(3):1027-32.


Alveolar macrophage function is selectively altered after endotoxemia in rats.

Christman JW, Petras SF, Hacker M, Absher PM, Davis GS.

Infect Immun. 1988 May;56(5):1254-9.


Survival of Bacillus thuringiensis Spores in Soil.

Petras SF, Casida LE.

Appl Environ Microbiol. 1985 Dec;50(6):1496-501.

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