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Improved performance predicting clarithromycin resistance in Mycobacterium abscessus on an independent dataset.

Lipworth S, Hough N, Buchanan R, Smith EG, Robinson E, Alexander E, Peto T, Crook D, Walker T.

Antimicrob Agents Chemother. 2019 Jun 3. pii: AAC.00400-19. doi: 10.1128/AAC.00400-19. [Epub ahead of print]


Promising Artificial Intelligence-Machine Learning-Deep Learning Algorithms in Ophthalmology.

Balyen L, Peto T.

Asia Pac J Ophthalmol (Phila). 2019 May-Jun;8(3):264-272. doi: 10.22608/APO.2018479. Epub 2019 May 31. Review.


Zinc Nutrition and Inflammation in the Aging Retina.

Gilbert R, Peto T, Lengyel I, Emri E.

Mol Nutr Food Res. 2019 May 30:e1801049. doi: 10.1002/mnfr.201801049. [Epub ahead of print] Review.


A qualitative study on barriers and enablers to uptake of diabetic retinopathy screening by people with diabetes in the Western Province of Sri Lanka.

Piyasena MMPN, Murthy GVS, Yip JLY, Gilbert C, Peto T, Premarathna M, Zuurmond M.

Trop Med Health. 2019 May 17;47:34. doi: 10.1186/s41182-019-0160-y. eCollection 2019.


Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR.

Grauslund J, Frydkjaer-Olsen U, Peto T, Fernández-Carneado J, Ponsati B, Hernández C, Cunha-Vaz J, Simó R; EUROCONDOR.

Invest Ophthalmol Vis Sci. 2019 May 1;60(6):2257-2262. doi: 10.1167/iovs.18-26487.


Making the most of cataract surgery in patients with diabetes.

Peto T, Sandi F, Kumar V.

Community Eye Health. 2019;31(104):80-81. No abstract available.


Novel Approaches to Control Malaria in Forested Areas of Southeast Asia.

von Seidlein L, Peto TJ, Tripura R, Pell C, Yeung S, Kindermans JM, Dondorp A, Maude R.

Trends Parasitol. 2019 Jun;35(6):388-398. doi: 10.1016/ Epub 2019 May 7. Review.


Correction to: Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging.

Piyasena MMPN, Murthy GVS, Yip JLY, Gilbert C, Peto T, Gordon I, Hewage S, Kamalakannan S.

Syst Rev. 2019 Apr 30;8(1):106. doi: 10.1186/s13643-019-1023-7.


Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration.

Heesterbeek TJ, de Jong EK, Acar IE, Groenewoud JMM, Liefers B, Sánchez CI, Peto T, Hoyng CB, Pauleikhoff D, Hense HW, den Hollander AI.

Sci Rep. 2019 Apr 29;9(1):6611. doi: 10.1038/s41598-019-43144-3.


Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage.

Eyre DW, Didelot X, Buckley AM, Freeman J, Moura IB, Crook DW, Peto TEA, Walker AS, Wilcox MH, Dingle KE.

EBioMedicine. 2019 May;43:347-355. doi: 10.1016/j.ebiom.2019.04.038. Epub 2019 Apr 27.


Long-Term Outcome of Patients Operated with Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment.

Poulsen CD, Green A, Grauslund J, Peto T.

Ophthalmic Res. 2019 Apr 23:1-9. doi: 10.1159/000499130. [Epub ahead of print]


Systematic review on barriers and enablers for access to diabetic retinopathy screening services in different income settings.

Piyasena MMPN, Murthy GVS, Yip JLY, Gilbert C, Zuurmond M, Peto T, Gordon I, Hewage S, Kamalakannan S.

PLoS One. 2019 Apr 23;14(4):e0198979. doi: 10.1371/journal.pone.0198979. eCollection 2019.


Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2.

Pauleikhoff D, Bonelli R, Dubis AM, Gunnemann F, Rothaus K, Charbel Issa P, Heeren TF, Peto T, Clemons TE, Chew EY, Bird AC, Sallo FB; MacTel Study Group.

Acta Ophthalmol. 2019 Apr 9. doi: 10.1111/aos.14110. [Epub ahead of print]


Polymorphisms in Pvkelch12 and gene amplification of Pvplasmepsin4 in Plasmodium vivax from Thailand, Lao PDR and Cambodia.

Duanguppama J, Mathema VB, Tripura R, Day NPJ, Maxay M, Nguon C, von Seidlein L, Dhorda M, Peto TJ, Nosten F, White NJ, Dondorp AM, Imwong M.

Malar J. 2019 Apr 2;18(1):114. doi: 10.1186/s12936-019-2749-3.


National Eye Survey of Trinidad and Tobago (NESTT): prevalence, causes and risk factors for presenting vision impairment in adults over 40 years.

Braithwaite T, Verlander NQ, Peto T, Bartholomew D, Deomansingh F, Bridgemohan P, Saei A, Sharma S, Singh D, Ramsewak SS, Bourne RRA.

Br J Ophthalmol. 2019 Mar 26. pii: bjophthalmol-2018-313428. doi: 10.1136/bjophthalmol-2018-313428. [Epub ahead of print]


Community engagement, social context and coverage of mass anti-malarial administration: Comparative findings from multi-site research in the Greater Mekong sub-Region.

Pell CL, Adhikari B, Myo Thwin M, Kajeechiwa L, Nosten S, Nosten FH, Sahan KM, Smithuis FM, Nguyen TN, Hien TT, Tripura R, Peto TJ, Sanann N, Nguon C, Pongvongsa T, Phommasone K, Mayxay M, Mukaka M, Peerawaranun P, Kaehler N, Cheah PY, Day NPJ, White NJ, Dondorp AM, von Seidlein L.

PLoS One. 2019 Mar 25;14(3):e0214280. doi: 10.1371/journal.pone.0214280. eCollection 2019.


Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia.

van Aartsen JJ, Moore CE, Parry CM, Turner P, Phot N, Mao S, Suy K, Davies T, Giess A, Sheppard AE, Peto TEA, Day NPJ, Crook DW, Walker AS, Stoesser N.

BMC Microbiol. 2019 Mar 12;19(1):59. doi: 10.1186/s12866-019-1431-9.


A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Marwick CA, Coia J, Brown D, Buchanan S, Ijaz UZ, Goswami C, Douce G, Fawley WN, Wilcox MH, Peto TEA, Walker AS, Crook DW.

MBio. 2019 Mar 12;10(2). pii: e02790-18. doi: 10.1128/mBio.02790-18.


Cohort profile: design and methods in the eye and vision consortium of UK Biobank.

Chua SYL, Thomas D, Allen N, Lotery A, Desai P, Patel P, Muthy Z, Sudlow C, Peto T, Khaw PT, Foster PJ; UK Biobank Eye & Vision Consortium.

BMJ Open. 2019 Feb 21;9(2):e025077. doi: 10.1136/bmjopen-2018-025077.


SNP-IT Tool for Identifying Subspecies and Associated Lineages of Mycobacterium tuberculosis Complex.

Lipworth S, Jajou R, de Neeling A, Bradley P, van der Hoek W, Maphalala G, Bonnet M, Sanchez-Padilla E, Diel R, Niemann S, Iqbal Z, Smith G, Peto T, Crook D, Walker T, van Soolingen D.

Emerg Infect Dis. 2019 Mar;25(3):482-488. doi: 10.3201/eid2503.180894.


The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.

von Seidlein L, Peto TJ, Landier J, Nguyen TN, Tripura R, Phommasone K, Pongvongsa T, Lwin KM, Keereecharoen L, Kajeechiwa L, Thwin MM, Parker DM, Wiladphaingern J, Nosten S, Proux S, Corbel V, Tuong-Vy N, Phuc-Nhi TL, Son DH, Huong-Thu PN, Tuyen NTK, Tien NT, Dong LT, Hue DV, Quang HH, Nguon C, Davoeung C, Rekol H, Adhikari B, Henriques G, Phongmany P, Suangkanarat P, Jeeyapant A, Vihokhern B, van der Pluijm RW, Lubell Y, White LJ, Aguas R, Promnarate C, Sirithiranont P, Malleret B, Rénia L, Onsjö C, Chan XH, Chalk J, Miotto O, Patumrat K, Chotivanich K, Hanboonkunupakarn B, Jittmala P, Kaehler N, Cheah PY, Pell C, Dhorda M, Imwong M, Snounou G, Mukaka M, Peerawaranun P, Lee SJ, Simpson JA, Pukrittayakamee S, Singhasivanon P, Grobusch MP, Cobelens F, Smithuis F, Newton PN, Thwaites GE, Day NPJ, Mayxay M, Hien TT, Nosten FH, Dondorp AM, White NJ.

PLoS Med. 2019 Feb 15;16(2):e1002745. doi: 10.1371/journal.pmed.1002745. eCollection 2019 Feb.


How can interventions that target forest-goers be tailored to accelerate malaria elimination in the Greater Mekong Subregion? A systematic review of the qualitative literature.

Nofal SD, Peto TJ, Adhikari B, Tripura R, Callery J, Bui TM, von Seidlein L, Pell C.

Malar J. 2019 Feb 1;18(1):32. doi: 10.1186/s12936-019-2666-5.


DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.

Walker TM, Walker AS, Wilson DJ, Peto TEA, Crook DW, Shamout F; CRyPTIC consortium, Zhu T, Clifton DA.

Bioinformatics. 2019 Jan 28. doi: 10.1093/bioinformatics/btz067. [Epub ahead of print]


Orthostatic blood pressure variability is associated with lower visual contrast sensitivity function: Findings from The Irish Longitudinal Study on Aging.

Ní Bhuachalla B, McGarrigle CA, O'Leary N, Akuffo KO, Peto T, Beatty S, Kenny RA.

Exp Gerontol. 2019 May;119:14-24. doi: 10.1016/j.exger.2019.01.009. Epub 2019 Jan 22.


Fundus autofluorescence and spectral domain optical coherence tomography as predictors for long-term functional outcome in rhegmatogenous retinal detachment.

Poulsen CD, Petersen MP, Green A, Peto T, Grauslund J.

Graefes Arch Clin Exp Ophthalmol. 2019 Apr;257(4):715-723. doi: 10.1007/s00417-018-04222-w. Epub 2019 Jan 7.


[Transient diplopia and ophthalmoplegia following dental anaesthesia. Review of the literature and case report].

Seres L, Pethő G, Pető Z, Pető T.

Orv Hetil. 2018 Dec;159(52):2212-2216. doi: 10.1556/650.2018.31233. Hungarian.


How do we evaluate the role of focal/grid photocoagulation in the treatment of diabetic macular edema?

Blindbaek SL, Peto T, Grauslund J.

Acta Ophthalmol. 2019 Jun;97(4):339-346. doi: 10.1111/aos.13997. Epub 2018 Dec 21. Review.


WGS to determine the extent of Clostridioides difficile transmission in a high incidence setting in North Wales in 2015.

Eyre DW, Shaw R, Adams H, Cooper T, Crook DW, Griffin RM, Mannion P, Morgan M, Morris T, Perry M, Jones S, Peto TEA, Sutton J, Walker AS, Williams D, Craine N.

J Antimicrob Chemother. 2019 Apr 1;74(4):1092-1100. doi: 10.1093/jac/dky523.


Diagnostic Accuracy of Digital Retinal Fundus Image Analysis in Detecting Diabetic Maculopathy in Type 2 Diabetes Mellitus.

D'Aloisio R, Giglio R, Di Nicola M, De Giacinto C, Pastore MR, Tognetto D, Peto T.

Ophthalmic Res. 2019;61(2):100-106. doi: 10.1159/000494499. Epub 2018 Dec 14.


Retinal metabolic and structural alterations in response to aflibercept treatment in neovascular age-related macular degeneration.

Jakobsen DB, Torp TL, Stefansson E, Peto T, Grauslund J.

Acta Ophthalmol. 2018 Dec 13. doi: 10.1111/aos.13996. [Epub ahead of print]


Perceptions of asymptomatic malaria infection and their implications for malaria control and elimination in Laos.

Adhikari B, Phommasone K, Pongvongsa T, Soundala X, Koummarasy P, Henriques G, Peto TJ, Seidlein LV, White NJ, Day NPJ, Dondorp AM, Newton PN, Cheah PY, Mayxay M, Pell C.

PLoS One. 2018 Dec 11;13(12):e0208912. doi: 10.1371/journal.pone.0208912. eCollection 2018.


Development and Validation of a Diabetic Retinopathy Screening Modality Using a Hand-Held Nonmydriatic Digital Retinal Camera by Physician Graders at a Tertiary-Level Medical Clinic: Protocol for a Validation Study.

Piyasena MMPN, Gudlavalleti VSM, Gilbert C, Yip JL, Peto T, MacLeod D, Fonseka C, Kulatunga A, Bandutilake B, Dhanapala M, Pathirana L, Dissanayake H.

JMIR Res Protoc. 2018 Dec 10;7(12):e10900. doi: 10.2196/10900.


Application of machine learning techniques to tuberculosis drug resistance analysis.

Kouchaki S, Yang Y, Walker TM, Walker AS, Wilson DJ, Peto TEA, Crook DW, Clifton DA; CRyPTIC consortium.

Bioinformatics. 2018 Nov 21. doi: 10.1093/bioinformatics/bty949. [Epub ahead of print]


Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging.

Piyasena MMPN, Murthy GVS, Yip JLY, Gilbert C, Peto T, Gordon I, Hewage S, Kamalakannan S.

Syst Rev. 2018 Nov 7;7(1):182. doi: 10.1186/s13643-018-0846-y. Erratum in: Syst Rev. 2019 Apr 30;8(1):106.


Using linked electronic health records to report healthcare-associated infections.

Quan TP, Hope R, Clarke T, Moroney R, Butcher L, Knight P, Crook D, Hopkins S, Peto TEA, Johnson AP, Walker AS.

PLoS One. 2018 Nov 7;13(11):e0206860. doi: 10.1371/journal.pone.0206860. eCollection 2018.


Whole-Genome Sequencing for Predicting Clarithromycin Resistance in Mycobacterium abscessus.

Lipworth S, Hough N, Leach L, Morgan M, Jeffery K, Andersson M, Robinson E, Smith EG, Crook D, Peto T, Walker T.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01204-18. doi: 10.1128/AAC.01204-18. Print 2019 Jan.


Automated detection of bacterial growth on 96-well plates for high-throughput drug susceptibility testing of Mycobacterium tuberculosis.

Fowler PW, Gibertoni Cruz AL, Hoosdally SJ, Jarrett L, Borroni E, Chiacchiaretta M, Rathod P, Lehmann S, Molodtsov N, Walker TM, Robinson E, Hoffmann H, Peto TEA, Cirillo DM, Smith GE, Crook DW.

Microbiology. 2018 Dec;164(12):1522-1530. doi: 10.1099/mic.0.000733. Epub 2018 Oct 23.


The clinical relevance of visualising the peripheral retina.

Quinn N, Csincsik L, Flynn E, Curcio CA, Kiss S, Sadda SR, Hogg R, Peto T, Lengyel I.

Prog Retin Eye Res. 2019 Jan;68:83-109. doi: 10.1016/j.preteyeres.2018.10.001. Epub 2018 Oct 10. Review.


Intralesional Macular Atrophy in Anti-Vascular Endothelial Growth Factor Therapy for Age-Related Macular Degeneration in the IVAN Trial.

Bailey C, Scott LJ, Rogers CA, Reeves BC, Hamill B, Peto T, Chakravarthy U, Harding SP; writing committee for the IVAN Study Group.

Ophthalmology. 2019 Jan;126(1):75-86. doi: 10.1016/j.ophtha.2018.07.013. Epub 2018 Oct 6.


Asymptomatic Natural Human Infections With the Simian Malaria Parasites Plasmodium cynomolgi and Plasmodium knowlesi.

Imwong M, Madmanee W, Suwannasin K, Kunasol C, Peto TJ, Tripura R, von Seidlein L, Nguon C, Davoeung C, Day NPJ, Dondorp AM, White NJ.

J Infect Dis. 2019 Feb 15;219(5):695-702. doi: 10.1093/infdis/jiy519.


Detection of Viral Pathogens With Multiplex Nanopore MinION Sequencing: Be Careful With Cross-Talk.

Xu Y, Lewandowski K, Lumley S, Pullan S, Vipond R, Carroll M, Foster D, Matthews PC, Peto T, Crook D.

Front Microbiol. 2018 Sep 19;9:2225. doi: 10.3389/fmicb.2018.02225. eCollection 2018.


A Candida auris Outbreak and Its Control in an Intensive Care Setting.

Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP, Griffiths D, George S, Butcher L, Morgan M, Newnham R, Sunderland M, Clarke T, Foster D, Hoffman P, Borman AM, Johnson EM, Moore G, Brown CS, Walker AS, Peto TEA, Crook DW, Jeffery KJM.

N Engl J Med. 2018 Oct 4;379(14):1322-1331. doi: 10.1056/NEJMoa1714373.


Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.

CRyPTIC Consortium and the 100,000 Genomes Project, Allix-Béguec C, Arandjelovic I, Bi L, Beckert P, Bonnet M, Bradley P, Cabibbe AM, Cancino-Muñoz I, Caulfield MJ, Chaiprasert A, Cirillo DM, Clifton DA, Comas I, Crook DW, De Filippo MR, de Neeling H, Diel R, Drobniewski FA, Faksri K, Farhat MR, Fleming J, Fowler P, Fowler TA, Gao Q, Gardy J, Gascoyne-Binzi D, Gibertoni-Cruz AL, Gil-Brusola A, Golubchik T, Gonzalo X, Grandjean L, He G, Guthrie JL, Hoosdally S, Hunt M, Iqbal Z, Ismail N, Johnston J, Khanzada FM, Khor CC, Kohl TA, Kong C, Lipworth S, Liu Q, Maphalala G, Martinez E, Mathys V, Merker M, Miotto P, Mistry N, Moore DAJ, Murray M, Niemann S, Omar SV, Ong RT, Peto TEA, Posey JE, Prammananan T, Pym A, Rodrigues C, Rodrigues M, Rodwell T, Rossolini GM, Sánchez Padilla E, Schito M, Shen X, Shendure J, Sintchenko V, Sloutsky A, Smith EG, Snyder M, Soetaert K, Starks AM, Supply P, Suriyapol P, Tahseen S, Tang P, Teo YY, Thuong TNT, Thwaites G, Tortoli E, van Soolingen D, Walker AS, Walker TM, Wilcox M, Wilson DJ, Wyllie D, Yang Y, Zhang H, Zhao Y, Zhu B.

N Engl J Med. 2018 Oct 11;379(15):1403-1415. doi: 10.1056/NEJMoa1800474. Epub 2018 Sep 26.


Real-time analysis of nanopore-based metagenomic sequencing from infected orthopaedic devices.

Sanderson ND, Street TL, Foster D, Swann J, Atkins BL, Brent AJ, McNally MA, Oakley S, Taylor A, Peto TEA, Crook DW, Eyre DW.

BMC Genomics. 2018 Sep 27;19(1):714. doi: 10.1186/s12864-018-5094-y.


The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies.

Gattoussi S, Buitendijk GHS, Peto T, Leung I, Schmitz-Valckenberg S, Oishi A, Wolf S, Deák G, Delcourt C, Klaver CCW, Korobelnik JF; European Eye Epidemiology (E3) consortium.

Acta Ophthalmol. 2019 Jun;97(4):364-371. doi: 10.1111/aos.13883. Epub 2018 Sep 22.


Strengthen Village Malaria Reporting to Better Target Reservoirs of Persistent Infections in Southeast Asia.

Peto TJ, Tripura R, Maude RJ.

Clin Infect Dis. 2019 Mar 5;68(6):1066-1067. doi: 10.1093/cid/ciy793. No abstract available.


Identifying Mixed Mycobacterium tuberculosis Infection and Laboratory Cross-Contamination during Mycobacterial Sequencing Programs.

Wyllie DH, Robinson E, Peto T, Crook DW, Ajileye A, Rathod P, Allen R, Jarrett L, Smith EG, Walker AS.

J Clin Microbiol. 2018 Oct 25;56(11). pii: e00923-18. doi: 10.1128/JCM.00923-18. Print 2018 Nov.


Trends over time in Escherichia coli bloodstream infections, urinary tract infections, and antibiotic susceptibilities in Oxfordshire, UK, 1998-2016: a study of electronic health records.

Vihta KD, Stoesser N, Llewelyn MJ, Quan TP, Davies T, Fawcett NJ, Dunn L, Jeffery K, Butler CC, Hayward G, Andersson M, Morgan M, Oakley S, Mason A, Hopkins S, Wyllie DH, Crook DW, Wilcox MH, Johnson AP, Peto TEA, Walker AS.

Lancet Infect Dis. 2018 Oct;18(10):1138-1149. doi: 10.1016/S1473-3099(18)30353-0. Epub 2018 Aug 17.


A Quantitative Evaluation of MIRU-VNTR Typing Against Whole-Genome Sequencing for Identifying Mycobacterium tuberculosis Transmission: A Prospective Observational Cohort Study.

Wyllie DH, Davidson JA, Grace Smith E, Rathod P, Crook DW, Peto TEA, Robinson E, Walker T, Campbell C.

EBioMedicine. 2018 Aug;34:122-130. doi: 10.1016/j.ebiom.2018.07.019. Epub 2018 Aug 1.

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