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Items: 25


Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.

Ridinger J, Koeneke E, Kolbinger FR, Koerholz K, Mahboobi S, Hellweg L, Gunkel N, Miller AK, Peterziel H, Schmezer P, Hamacher-Brady A, Witt O, Oehme I.

Sci Rep. 2018 Jul 3;8(1):10039. doi: 10.1038/s41598-018-28265-5.


A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment.

Shen J, Najafi S, Stäble S, Fabian J, Koeneke E, Kolbinger FR, Wrobel JK, Meder B, Distel M, Heimburg T, Sippl W, Jung M, Peterziel H, Kranz D, Boutros M, Westermann F, Witt O, Oehme I.

Cell Death Differ. 2018 Mar 7. doi: 10.1038/s41418-018-0080-0. [Epub ahead of print]


An advanced glioma cell invasion assay based on organotypic brain slice cultures.

Eisemann T, Costa B, Strelau J, Mittelbronn M, Angel P, Peterziel H.

BMC Cancer. 2018 Jan 30;18(1):103. doi: 10.1186/s12885-018-4007-4.


Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.

Bingel C, Koeneke E, Ridinger J, Bittmann A, Sill M, Peterziel H, Wrobel JK, Rettig I, Milde T, Fernekorn U, Weise F, Schober A, Witt O, Oehme I.

Cell Death Dis. 2017 Aug 24;8(8):e3013. doi: 10.1038/cddis.2017.398.


Derivation of Pluripotent Cells from Mouse SSCs Seems to Be Age Dependent.

Azizi H, Conrad S, Hinz U, Asgari B, Nanus D, Peterziel H, Hajizadeh Moghaddam A, Baharvand H, Skutella T.

Stem Cells Int. 2016;2016:8216312. doi: 10.1155/2016/8216312. Epub 2015 Nov 9.


Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro.

Merz C, Strecker A, Sykora J, Hill O, Fricke H, Angel P, Gieffers C, Peterziel H.

Anticancer Drugs. 2015 Aug;26(7):716-27. doi: 10.1097/CAD.0000000000000237.


KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.

Brockschmidt A, Trost D, Peterziel H, Zimmermann K, Ehrler M, Grassmann H, Pfenning PN, Waha A, Wohlleber D, Brockschmidt FF, Jugold M, Hoischen A, Kalla C, Waha A, Seifert G, Knolle PA, Latz E, Hans VH, Wick W, Pfeifer A, Angel P, Weber RG.

Brain. 2012 Apr;135(Pt 4):1027-41. doi: 10.1093/brain/aws045. Epub 2012 Mar 16.


Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation.

Peterziel H, Müller J, Danner A, Barbus S, Liu HK, Radlwimmer B, Pietsch T, Lichter P, Schütz G, Hess J, Angel P.

Neuro Oncol. 2012 Apr;14(4):426-39. doi: 10.1093/neuonc/nos055. Epub 2012 Mar 6.


Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment.

Krenzer S, Peterziel H, Mauch C, Blaber SI, Blaber M, Angel P, Hess J.

J Invest Dermatol. 2011 Nov;131(11):2281-8. doi: 10.1038/jid.2011.190. Epub 2011 Jul 14.


F-spondin regulates neuronal survival through activation of disabled-1 in the chicken ciliary ganglion.

Peterziel H, Sackmann T, Strelau J, Kuhn PH, Lichtenthaler SF, Marom K, Klar A, Unsicker K.

Mol Cell Neurosci. 2011 Feb;46(2):483-97. doi: 10.1016/j.mcn.2010.12.001. Epub 2010 Dec 9.


Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival.

Ernst A, Hofmann S, Ahmadi R, Becker N, Korshunov A, Engel F, Hartmann C, Felsberg J, Sabel M, Peterziel H, Durchdewald M, Hess J, Barbus S, Campos B, Starzinski-Powitz A, Unterberg A, Reifenberger G, Lichter P, Herold-Mende C, Radlwimmer B.

Clin Cancer Res. 2009 Nov 1;15(21):6541-50. doi: 10.1158/1078-0432.CCR-09-0695. Epub 2009 Oct 27.


Expression and putative functions of GDF-15, a member of the TGF-beta superfamily, in human glioma and glioblastoma cell lines.

Strelau J, Schmeer C, Peterziel H, Sackmann T, Herold-Mende C, Steiner H, Weller M, Unsicker K.

Cancer Lett. 2008 Oct 18;270(1):30-9. doi: 10.1016/j.canlet.2008.04.042. Epub 2008 Jun 11.


The androgen receptor as mediator of gene expression and signal transduction pathways.

Cato AC, Peterziel H.

Trends Endocrinol Metab. 1998 May-Jun;9(4):150-4.


Specificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors.

Peterziel H, Paech T, Strelau J, Unsicker K, Krieglstein K.

J Neurochem. 2007 Dec;103(6):2491-504. Epub 2007 Oct 22.


GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action.

Schober A, Peterziel H, von Bartheld CS, Simon H, Krieglstein K, Unsicker K.

Neurobiol Dis. 2007 Feb;25(2):378-91. Epub 2006 Dec 1.


Transforming growth factor beta2 is released from PC12 cells via the regulated pathway of secretion.

Specht H, Peterziel H, Bajohrs M, Gerdes HH, Krieglstein K, Unsicker K.

Mol Cell Neurosci. 2003 Jan;22(1):75-86.


TGFbeta induces GDNF responsiveness in neurons by recruitment of GFRalpha1 to the plasma membrane.

Peterziel H, Unsicker K, Krieglstein K.

J Cell Biol. 2002 Oct 14;159(1):157-67. Epub 2002 Oct 7.


Rapid signalling by androgen receptor in prostate cancer cells.

Peterziel H, Mink S, Schonert A, Becker M, Klocker H, Cato AC.

Oncogene. 1999 Nov 4;18(46):6322-9.


Mechanism of androgen receptor activation and possible implications for chemoprevention trials.

Klocker H, Culig Z, Eder IE, Nessler-Menardi C, Hobisch A, Putz T, Bartsch G, Peterziel H, Cato AC.

Eur Urol. 1999;35(5-6):413-9. Review.


Expression, structure, and function of androgen receptor in advanced prostatic carcinoma.

Culig Z, Hobisch A, Hittmair A, Peterziel H, Cato AC, Bartsch G, Klocker H.

Prostate. 1998 Apr 1;35(1):63-70. Review.


Hyperactive androgen receptor in prostate cancer: what does it mean for new therapy concepts?

Culig Z, Hobisch A, Hittmair A, Peterziel H, Radmayr C, Bartsch G, Cato AC, Klocker H.

Histol Histopathol. 1997 Jul;12(3):781-6. Review.


Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression.

Schneikert J, Peterziel H, Defossez PA, Klocker H, de Launoit Y, Cato AC.

J Biol Chem. 1996 Sep 27;271(39):23907-13.


CAG-repeat expansion in androgen receptor in Kennedy's disease is not a loss of function mutation.

Neuschmid-Kaspar F, Gast A, Peterziel H, Schneikert J, Muigg A, Ransmayr G, Klocker H, Bartsch G, Cato AC.

Mol Cell Endocrinol. 1996 Mar 25;117(2):149-56.


Activation of two mutant androgen receptors from human prostatic carcinoma by adrenal androgens and metabolic derivatives of testosterone.

Culig Z, Stober J, Gast A, Peterziel H, Hobisch A, Radmayr C, Hittmair A, Bartsch G, Cato AC, Klocker H.

Cancer Detect Prev. 1996;20(1):68-75.


Mutant androgen receptors in prostatic tumors distinguish between amino-acid-sequence requirements for transactivation and ligand binding.

Peterziel H, Culig Z, Stober J, Hobisch A, Radmayr C, Bartsch G, Klocker H, Cato AC.

Int J Cancer. 1995 Nov 15;63(4):544-50.


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