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Items: 15


Charting cellular identity during human in vitro β-cell differentiation.

Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA.

Nature. 2019 May;569(7756):368-373. doi: 10.1038/s41586-019-1168-5. Epub 2019 May 8.


Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System.

Rigamonti A, Repetti GG, Sun C, Price FD, Reny DC, Rapino F, Weisinger K, Benkler C, Peterson QP, Davidow LS, Hansson EM, Rubin LL.

Stem Cell Reports. 2016 Jun 14;6(6):993-1008. doi: 10.1016/j.stemcr.2016.05.010.


Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.

Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15498-503. doi: 10.1073/pnas.1513872112. Epub 2015 Nov 30.


Generation of functional human pancreatic β cells in vitro.

Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA.

Cell. 2014 Oct 9;159(2):428-39. doi: 10.1016/j.cell.2014.09.040.


Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.

Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA.

Elife. 2014 Sep 16;3:e02809. doi: 10.7554/eLife.02809.


Differential effects of procaspase-3 activating compounds in the induction of cancer cell death.

West DC, Qin Y, Peterson QP, Thomas DL, Palchaudhuri R, Morrison KC, Lucas PW, Palmer AE, Fan TM, Hergenrother PJ.

Mol Pharm. 2012 May 7;9(5):1425-34. doi: 10.1021/mp200673n. Epub 2012 Apr 27.


Discovery and canine preclinical assessment of a nontoxic procaspase-3-activating compound.

Peterson QP, Hsu DC, Novotny CJ, West DC, Kim D, Schmit JM, Dirikolu L, Hergenrother PJ, Fan TM.

Cancer Res. 2010 Sep 15;70(18):7232-41. doi: 10.1158/0008-5472.CAN-10-0766. Epub 2010 Sep 7.


Pharmacokinetics and derivation of an anticancer dosing regimen for PAC-1, a preferential small molecule activator of procaspase-3, in healthy dogs.

Lucas PW, Schmit JM, Peterson QP, West DC, Hsu DC, Novotny CJ, Dirikolu L, Churchwell MI, Doerge DR, Garrett LD, Hergenrother PJ, Fan TM.

Invest New Drugs. 2011 Oct;29(5):901-11. doi: 10.1007/s10637-010-9445-z. Epub 2010 May 25.


Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis.

Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ.

Nat Protoc. 2010 Feb;5(2):294-302. doi: 10.1038/nprot.2009.223. Epub 2010 Jan 28.


Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3.

Peterson QP, Hsu DC, Goode DR, Novotny CJ, Totten RK, Hergenrother PJ.

J Med Chem. 2009 Sep 24;52(18):5721-31. doi: 10.1021/jm900722z.


PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition.

Peterson QP, Goode DR, West DC, Ramsey KN, Lee JJ, Hergenrother PJ.

J Mol Biol. 2009 Apr 24;388(1):144-58. doi: 10.1016/j.jmb.2009.03.003. Epub 2009 Mar 10.


Identification of a novel retinoid by small molecule screening with zebrafish embryos.

Sachidanandan C, Yeh JR, Peterson QP, Peterson RT.

PLoS One. 2008 Apr 9;3(4):e1947. doi: 10.1371/journal.pone.0001947.


AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression.

Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT.

Development. 2008 Jan;135(2):401-10.


Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling.

Hong CC, Peterson QP, Hong JY, Peterson RT.

Curr Biol. 2006 Jul 11;16(13):1366-72.


Determination of perchlorate in drinking water by ion chromatography using macrocycle-based concentration and separation methods.

Lamb JD, Simpson D, Jensen BD, Gardner JS, Peterson QP.

J Chromatogr A. 2006 Jun 16;1118(1):100-5. Epub 2006 Mar 3.


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