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Items: 1 to 50 of 99

1.

Proof of region-specific multipotent progenitors in human breast epithelia.

Fridriksdottir AJ, Villadsen R, Morsing M, Klitgaard MC, Kim J, Petersen OW, Rønnov-Jessen L.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10102-E10111. doi: 10.1073/pnas.1714063114. Epub 2017 Nov 6.

2.

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.

Hopkinson BM, Klitgaard MC, Petersen OW, Villadsen R, Rønnov-Jessen L, Kim J.

Oncotarget. 2017 Feb 7;8(6):10580-10593. doi: 10.18632/oncotarget.14554.

3.

Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections.

Sørensen KM, Meldgaard T, Melchjorsen CJ, Fridriksdottir AJ, Pedersen H, Petersen OW, Kristensen P.

BMC Cancer. 2017 Jan 5;17(1):19. doi: 10.1186/s12885-016-2987-5.

4.

Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.

Morsing M, Klitgaard MC, Jafari A, Villadsen R, Kassem M, Petersen OW, Rønnov-Jessen L.

Breast Cancer Res. 2016 Nov 3;18(1):108.

5.

Raising an Antibody Specific to Breast Cancer Subpopulations Using Phage Display on Tissue Sections.

Larsen SA, Meldgaard T, Fridriksdottir AJ, Lykkemark S, Poulsen PC, Overgaard LF, Petersen HB, Petersen OW, Kristensen P.

Cancer Genomics Proteomics. 2016 Jan-Feb;13(1):21-30.

PMID:
26708596
6.

Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture.

Fridriksdottir AJ, Kim J, Villadsen R, Klitgaard MC, Hopkinson BM, Petersen OW, Rønnov-Jessen L.

Nat Commun. 2015 Nov 13;6:8786. doi: 10.1038/ncomms9786.

7.

Selection of a breast cancer subpopulation-specific antibody using phage display on tissue sections.

Larsen SA, Meldgaard T, Fridriksdottir AJ, Lykkemark S, Poulsen PC, Overgaard LF, Petersen HB, Petersen OW, Kristensen P.

Immunol Res. 2015 Jul;62(3):263-72. doi: 10.1007/s12026-015-8657-x.

8.

A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched.

Balk-Møller E, Kim J, Hopkinson B, Timmermans-Wielenga V, Petersen OW, Villadsen R.

Am J Pathol. 2014 Apr;184(4):1198-208. doi: 10.1016/j.ajpath.2013.12.013.

PMID:
24655379
9.

Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells.

Vaapil M, Helczynska K, Villadsen R, Petersen OW, Johansson E, Beckman S, Larsson C, Påhlman S, Jögi A.

PLoS One. 2012;7(9):e46543. doi: 10.1371/journal.pone.0046543. Epub 2012 Sep 28.

10.

Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis.

Leth-Larsen R, Terp MG, Christensen AG, Elias D, Kühlwein T, Jensen ON, Petersen OW, Ditzel HJ.

Mol Med. 2012 Sep 25;18:1109-21. doi: 10.2119/molmed.2012.00091.

11.

Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.

Garbe JC, Pepin F, Pelissier FA, Sputova K, Fridriksdottir AJ, Guo DE, Villadsen R, Park M, Petersen OW, Borowsky AD, Stampfer MR, Labarge MA.

Cancer Res. 2012 Jul 15;72(14):3687-701. doi: 10.1158/0008-5472.CAN-12-0157. Epub 2012 May 2.

12.

Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.

Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6124-9. doi: 10.1073/pnas.1203203109. Epub 2012 Mar 27.

13.

Mammary gland stem cells: current status and future challenges.

Fridriksdottir AJ, Petersen OW, Rønnov-Jessen L.

Int J Dev Biol. 2011;55(7-9):719-29. doi: 10.1387/ijdb.113373af. Review.

14.

Endothelial induced EMT in breast epithelial cells with stem cell properties.

Sigurdsson V, Hilmarsdottir B, Sigmundsdottir H, Fridriksdottir AJ, Ringnér M, Villadsen R, Borg A, Agnarsson BA, Petersen OW, Magnusson MK, Gudjonsson T.

PLoS One. 2011;6(9):e23833. doi: 10.1371/journal.pone.0023833. Epub 2011 Sep 6.

15.

[Basic stem cell biology and cancer].

Porse BT, Petersen OW, Helin K.

Ugeskr Laeger. 2010 Sep 20;172(38):2600-3. Danish.

PMID:
20920403
16.

Stem cells in the human breast.

Petersen OW, Polyak K.

Cold Spring Harb Perspect Biol. 2010 May;2(5):a003160. doi: 10.1101/cshperspect.a003160. Review.

17.

Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment.

de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L.

Am J Pathol. 2010 Mar;176(3):1229-40. doi: 10.2353/ajpath.2010.090648. Epub 2010 Feb 4.

18.

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments.

LaBarge MA, Nelson CM, Villadsen R, Fridriksdottir A, Ruth JR, Stampfer MR, Petersen OW, Bissell MJ.

Integr Biol (Camb). 2009 Jan;1(1):70-9. doi: 10.1039/b816472j. Epub 2008 Nov 12.

19.

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.

Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, Spellman PT, Lorenz K, Lee EH, Barcellos-Hoff MH, Petersen OW, Gray JW, Bissell MJ.

Mol Oncol. 2007 Jun;1(1):84-96. doi: 10.1016/j.molonc.2007.02.004.

20.

A human breast cell model of preinvasive to invasive transition.

Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, Chen DJ, Petersen OW, Gray JW, Bissell MJ.

Cancer Res. 2008 Mar 1;68(5):1378-87. doi: 10.1158/0008-5472.CAN-07-2225.

21.

[Pathogenesis of breast cancer].

Petersen OW, Celis JE.

Ugeskr Laeger. 2007 Sep 3;169(36):2968-72. Review. Danish.

PMID:
17953870
22.

Of microenvironments and mammary stem cells.

LaBarge MA, Petersen OW, Bissell MJ.

Stem Cell Rev. 2007 Jun;3(2):137-46. Review.

23.

Evidence for a stem cell hierarchy in the adult human breast.

Villadsen R, Fridriksdottir AJ, Rønnov-Jessen L, Gudjonsson T, Rank F, LaBarge MA, Bissell MJ, Petersen OW.

J Cell Biol. 2007 Apr 9;177(1):87-101.

24.

Human breast microvascular endothelial cells retain phenotypic traits in long-term finite life span culture.

Sigurdsson V, Fridriksdottir AJ, Kjartansson J, Jonasson JG, Steinarsdottir M, Petersen OW, Ogmundsdottir HM, Gudjonsson T.

In Vitro Cell Dev Biol Anim. 2006 Nov-Dec;42(10):332-40.

PMID:
17316068
25.

Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia.

Gudjonsson T, Adriance MC, Sternlicht MD, Petersen OW, Bissell MJ.

J Mammary Gland Biol Neoplasia. 2005 Jul;10(3):261-72. Review.

26.

Estrogenic effect of soy isoflavones on mammary gland morphogenesis and gene expression profile.

Thomsen AR, Almstrup K, Nielsen JE, Sørensen IK, Petersen OW, Leffers H, Breinholt VM.

Toxicol Sci. 2006 Oct;93(2):357-68. Epub 2006 Jun 6.

PMID:
16757570
27.

Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.

Stein T, Price KN, Morris JS, Heath VJ, Ferrier RK, Bell AK, Pringle MA, Villadsen R, Petersen OW, Sauter G, Bryson G, Mallon EA, Gusterson BA.

Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6872-9.

28.

Myoepithelial cells: good fences make good neighbors.

Adriance MC, Inman JL, Petersen OW, Bissell MJ.

Breast Cancer Res. 2005;7(5):190-7. Epub 2005 Jul 12.

29.

Maintenance of cell type diversification in the human breast.

Fridriksdottir AJ, Villadsen R, Gudjonsson T, Petersen OW.

J Mammary Gland Biol Neoplasia. 2005 Jan;10(1):61-74. Review.

PMID:
15886887
30.

Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2.

Kaminker P, Plachot C, Kim SH, Chung P, Crippen D, Petersen OW, Bissell MJ, Campisi J, Lelièvre SA.

J Cell Sci. 2005 Mar 15;118(Pt 6):1321-30. Epub 2005 Mar 1.

31.

Immortalization protocols used in cell culture models of human breast morphogenesis.

Gudjonsson T, Villadsen R, Rønnov-Jessen L, Petersen OW.

Cell Mol Life Sci. 2004 Oct;61(19-20):2523-34. Review.

PMID:
15526159
32.

Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia.

Petersen OW, Gudjonsson T, Villadsen R, Bissell MJ, Rønnov-Jessen L.

Cell Prolif. 2003 Oct;36 Suppl 1:33-44. Review.

33.

Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression.

Nielsen HL, Gudjonsson T, Villadsen R, Rønnov-Jessen L, Petersen OW.

In Vitro Cell Dev Biol Anim. 2003 Jul-Aug;39(7):297-303.

PMID:
12908855
34.

To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia.

Gudjonsson T, Rønnov-Jessen L, Villadsen R, Bissell MJ, Petersen OW.

Methods. 2003 Jul;30(3):247-55.

35.

Characterization of a novel breast carcinoma xenograft and cell line derived from a BRCA1 germ-line mutation carrier.

Johannsson OT, Staff S, Vallon-Christersson J, Kytöla S, Gudjonsson T, Rennstam K, Hedenfalk IA, Adeyinka A, Kjellén E, Wennerberg J, Baldetorp B, Petersen OW, Olsson H, Oredsson S, Isola J, Borg A.

Lab Invest. 2003 Mar;83(3):387-96.

PMID:
12649339
36.

Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma.

Petersen OW, Nielsen HL, Gudjonsson T, Villadsen R, Rank F, Niebuhr E, Bissell MJ, Rønnov-Jessen L.

Am J Pathol. 2003 Feb;162(2):391-402.

37.

The organizing principle: microenvironmental influences in the normal and malignant breast.

Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW.

Differentiation. 2002 Dec;70(9-10):537-46. Review.

38.

Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts.

Wang F, Hansen RK, Radisky D, Yoneda T, Barcellos-Hoff MH, Petersen OW, Turley EA, Bissell MJ.

J Natl Cancer Inst. 2002 Oct 2;94(19):1494-503.

39.
40.

Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer.

Nielsen HL, Rønnov-Jessen L, Villadsen R, Petersen OW.

Genomics. 2002 May;79(5):703-10.

PMID:
11991720
41.

Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties.

Gudjonsson T, Villadsen R, Nielsen HL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Genes Dev. 2002 Mar 15;16(6):693-706.

42.

Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition.

Gudjonsson T, Rønnov-Jessen L, Villadsen R, Rank F, Bissell MJ, Petersen OW.

J Cell Sci. 2002 Jan 1;115(Pt 1):39-50.

43.

The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion.

Petersen OW, Lind Nielsen H, Gudjonsson T, Villadsen R, Rønnov-Jessen L, Bissell MJ.

Breast Cancer Res. 2001;3(4):213-7. Epub 2001 Jun 12. Review.

44.

AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression.

Chen HM, Schmeichel KL, Mian IS, Lelièvre S, Petersen OW, Bissell MJ.

Mol Biol Cell. 2000 Apr;11(4):1357-67.

45.

Tissue structure, nuclear organization, and gene expression in normal and malignant breast.

Bissell MJ, Weaver VM, Lelièvre SA, Wang F, Petersen OW, Schmeichel KL.

Cancer Res. 1999 Apr 1;59(7 Suppl):1757-1763s; discussion 1763s-1764s. Review.

PMID:
10197593
46.

Human mammary luminal epithelial cells contain progenitors to myoepithelial cells.

Péchoux C, Gudjonsson T, Ronnov-Jessen L, Bissell MJ, Petersen OW.

Dev Biol. 1999 Feb 1;206(1):88-99.

47.

Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology.

Wang F, Weaver VM, Petersen OW, Larabell CA, Dedhar S, Briand P, Lupu R, Bissell MJ.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14821-6.

48.

Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus.

Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14711-6.

49.

Differentiation and cancer in the mammary gland: shedding light on an old dichotomy.

Petersen OW, Rønnov-Jessen L, Weaver VM, Bissell MJ.

Adv Cancer Res. 1998;75:135-61. Review.

50.

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies.

Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ.

J Cell Biol. 1997 Apr 7;137(1):231-45.

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