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Prediction of active human dose: learnings from 20 years of Merck KGaA experience, illustrated by case studies.

Peters SA, Petersson C, Blaukat A, Halle JP, Dolgos H.

Drug Discov Today. 2020 Jan 22. pii: S1359-6446(20)30028-3. doi: 10.1016/j.drudis.2020.01.002. [Epub ahead of print]


Sex differences in the risk of vascular disease associated with diabetes.

de Ritter R, de Jong M, Vos RC, van der Kallen CJH, Sep SJS, Woodward M, Stehouwer CDA, Bots ML, Peters SAE.

Biol Sex Differ. 2020 Jan 3;11(1):1. doi: 10.1186/s13293-019-0277-z. Review.


Meiotic recombination profiling of interspecific hybrid F1 tomato pollen by linked read sequencing.

Rommel Fuentes R, Hesselink T, Nieuwenhuis R, Bakker L, Schijlen E, van Dooijeweert W, Diaz Trivino S, de Haan JR, Sanchez Perez G, Zhang X, Fransz P, de Jong H, van Dijk ADJ, de Ridder D, Peters SA.

Plant J. 2019 Dec 9. doi: 10.1111/tpj.14640. [Epub ahead of print]


Adverse differences in cardiometabolic risk factor levels between individuals with pre-diabetes and normal glucose metabolism are more pronounced in women than in men: the Maastricht Study.

de Ritter R, Sep SJS, van der Kallen CJH, Schram MT, Koster A, Kroon AA, van Greevenbroek MMJ, Eussen SJPM, Dagnelie PC, de Jong M, Vos RC, Woodward M, Bots ML, Peters SAE, Stehouwer CDA.

BMJ Open Diabetes Res Care. 2019 Nov 15;7(1):e000787. doi: 10.1136/bmjdrc-2019-000787. eCollection 2019.


Pregnancy, pregnancy loss and the risk of diabetes in Chinese women: findings from the China Kadoorie Biobank.

Peters SAE, Yang L, Guo Y, Chen Y, Bian Z, Sun H, Li Y, Li L, Woodward M, Chen Z; China Kadoorie Biobank Collaboration Group.

Eur J Epidemiol. 2019 Nov 19. doi: 10.1007/s10654-019-00582-7. [Epub ahead of print]


Causal relationships between obesity and the leading causes of death in women and men.

Censin JC, Peters SAE, Bovijn J, Ferreira T, Pulit SL, Mägi R, Mahajan A, Holmes MV, Lindgren CM.

PLoS Genet. 2019 Oct 24;15(10):e1008405. doi: 10.1371/journal.pgen.1008405. eCollection 2019 Oct.


Evaluating the Role of Solubility in Oral Absorption of Poorly Water-Soluble Drugs Using Physiologically-Based Pharmacokinetic Modeling.

Fink C, Sun D, Wagner K, Schneider M, Bauer H, Dolgos H, Mäder K, Peters SA.

Clin Pharmacol Ther. 2019 Oct 14. doi: 10.1002/cpt.1672. [Epub ahead of print]


Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study.

de Jong M, Vos RC, de Ritter R, van der Kallen CJ, Sep SJ, Woodward M, Stehouwer CD, Bots ML, Peters SA.

BJGP Open. 2019 Jul 23;3(2). pii: bjgpopen19X101645. doi: 10.3399/bjgpopen19X101645. Print 2019 Jul.


Diabetes as a risk factor for heart failure in women and men: a systematic review and meta-analysis of 47 cohorts including 12 million individuals.

Ohkuma T, Komorita Y, Peters SAE, Woodward M.

Diabetologia. 2019 Sep;62(9):1550-1560. doi: 10.1007/s00125-019-4926-x. Epub 2019 Jul 18. Review.


Recommendations for the Design of Clinical Drug-Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically-Based Pharmacokinetic Model.

Chen Y, Cabalu TD, Callegari E, Einolf H, Liu L, Parrott N, Peters SA, Schuck E, Sharma P, Tracey H, Upreti VV, Zheng M, Zhu AZX, Hall SD.

CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):685-695. doi: 10.1002/psp4.12449. Epub 2019 Aug 7.


Trends in recruitment of women and reporting of sex differences in large-scale published randomized controlled trials in stroke.

Carcel C, Woodward M, Balicki G, Koroneos GL, Sousa DA, Cordonnier C, Lukaszyk C, Thompson K, Wang X, Davies L, Bassi M, Anderson CS, Peters SA, Sandset EC.

Int J Stroke. 2019 Dec;14(9):931-938. doi: 10.1177/1747493019851292. Epub 2019 May 27.


Sex Differences in the Assessment of Cardiovascular Risk in Primary Health Care: A Systematic Review.

Hyun KK, Millett ERC, Redfern J, Brieger D, Peters SAE, Woodward M.

Heart Lung Circ. 2019 Oct;28(10):1535-1548. doi: 10.1016/j.hlc.2019.04.005. Epub 2019 Apr 30. Review.


Prediction models for preeclampsia: A systematic review.

De Kat AC, Hirst J, Woodward M, Kennedy S, Peters SA.

Pregnancy Hypertens. 2019 Apr;16:48-66. doi: 10.1016/j.preghy.2019.03.005. Epub 2019 Mar 11.


Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders.

Saffouri GB, Shields-Cutler RR, Chen J, Yang Y, Lekatz HR, Hale VL, Cho JM, Battaglioli EJ, Bhattarai Y, Thompson KJ, Kalari KK, Behera G, Berry JC, Peters SA, Patel R, Schuetz AN, Faith JJ, Camilleri M, Sonnenburg JL, Farrugia G, Swann JR, Grover M, Knights D, Kashyap PC.

Nat Commun. 2019 May 1;10(1):2012. doi: 10.1038/s41467-019-09964-7.


Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS.

Edogawa S, Edwinson AL, Peters SA, Chikkamenahalli LL, Sundt W, Graves S, Gurunathan SV, Breen-Lyles M, Johnson S, Dyer R, Graham R, Chen J, Kashyap P, Farrugia G, Grover M.

Gut. 2020 Jan;69(1):62-73. doi: 10.1136/gutjnl-2018-317416. Epub 2019 Mar 28.


Association of menopausal characteristics and risk of coronary heart disease: a pan-European case-cohort analysis.

Dam V, van der Schouw YT, Onland-Moret NC, Groenwold RHH, Peters SAE, Burgess S, Wood AM, Chirlaque MD, Moons KGM, Oliver-Williams C, Schuit E, Tikk K, Weiderpass E, Holm M, Tjønneland A, Kühn T, Fortner RT, Trichopoulou A, Karakatsani A, La Vecchia C, Ferrari P, Gunter M, Masala G, Sieri S, Tumino R, Panico S, Boer JMA, Verschuren WMM, Salamanca-Fernández E, Arriola L, Moreno-Iribas C, Engström G, Melander O, Nordendahl M, Wennberg P, Key TJ, Colorado-Yohar S, Matullo G, Overvad K, Clavel-Chapelon F, Boeing H, Quiros JR, di Angelantonio E, Langenberg C, Sweeting MJ, Riboli E, Wareham NJ, Danesh J, Butterworth A.

Int J Epidemiol. 2019 Aug 1;48(4):1275-1285. doi: 10.1093/ije/dyz016.


Sex Differences in the Prevalence of, and Trends in, Cardiovascular Risk Factors, Treatment, and Control in the United States, 2001 to 2016.

Peters SAE, Muntner P, Woodward M.

Circulation. 2019 Feb 19;139(8):1025-1035. doi: 10.1161/CIRCULATIONAHA.118.035550.


A Retrospective Evaluation of Allometry, Population Pharmacokinetics, and Physiologically-Based Pharmacokinetics for Pediatric Dosing Using Clearance as a Surrogate.

Wu Q, Peters SA.

CPT Pharmacometrics Syst Pharmacol. 2019 Apr;8(4):220-229. doi: 10.1002/psp4.12385. Epub 2019 Feb 26.


Sex differences in the awareness, treatment, and control of hypertension in China: a systematic review with meta-analyses.

Redfern A, Peters SAE, Luo R, Cheng Y, Li C, Wang J, Anderson C, Wang H, Norton R.

Hypertens Res. 2019 Feb;42(2):273-283. doi: 10.1038/s41440-018-0154-x. Epub 2018 Dec 6.


Sex differences in risk factors for myocardial infarction: cohort study of UK Biobank participants.

Millett ERC, Peters SAE, Woodward M.

BMJ. 2018 Nov 7;363:k4247. doi: 10.1136/bmj.k4247.


Is there evidence for sex differences in the association between diabetes and cancer? Reply to Dankner R, Boker LK, Freedman LS [letter].

Ohkuma T, Peters SAE, Woodward M.

Diabetologia. 2019 Jan;62(1):201. doi: 10.1007/s00125-018-4761-5. Epub 2018 Nov 3. No abstract available.


Comparative analysis of repetitive sequences among species from the potato and the tomato clades.

Gaiero P, Vaio M, Peters SA, Schranz ME, de Jong H, Speranza PR.

Ann Bot. 2019 Feb 15;123(3):521-532. doi: 10.1093/aob/mcy186.


Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis.

O'Keeffe LM, Taylor G, Huxley RR, Mitchell P, Woodward M, Peters SAE.

BMJ Open. 2018 Oct 3;8(10):e021611. doi: 10.1136/bmjopen-2018-021611.


Established and novel risk factors for atrial fibrillation in women compared with men.

Peters SAE, Woodward M.

Heart. 2019 Feb;105(3):226-234. doi: 10.1136/heartjnl-2018-313630. Epub 2018 Aug 29.


Sex and gender reporting in global health: new editorial policies.

Peters SAE, Norton R.

BMJ Glob Health. 2018 Jul 26;3(4):e001038. doi: 10.1136/bmjgh-2018-001038. eCollection 2018. No abstract available.


Evaluation of Alignment between the Health Claims Nutrient Profiling Scoring Criterion (NPSC) and the Health Star Rating (HSR) Nutrient Profiling Models.

Dunford EK, Huang L, Peters SAE, Crino M, Neal BC, Ni Mhurchu C.

Nutrients. 2018 Aug 10;10(8). pii: E1065. doi: 10.3390/nu10081065.


Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping and assembly in Solanum species.

Gaiero P, Šimková H, Vrána J, Santiñaque FF, López-Carro B, Folle GA, van de Belt J, Peters SA, Doležel J, de Jong H.

MethodsX. 2018 Apr 10;5:328-336. doi: 10.1016/j.mex.2018.03.009. eCollection 2018.


Sex differences in the association between diabetes and cancer: a systematic review and meta-analysis of 121 cohorts including 20 million individuals and one million events.

Ohkuma T, Peters SAE, Woodward M.

Diabetologia. 2018 Oct;61(10):2140-2154. doi: 10.1007/s00125-018-4664-5. Epub 2018 Jul 20.


Sex differences in utilisation of hospital care in a state-sponsored health insurance programme providing access to free services in South India.

Shaikh M, Peters SAE, Woodward M, Norton R, Jha V.

BMJ Glob Health. 2018 Jun 29;3(3):e000859. doi: 10.1136/bmjgh-2018-000859. eCollection 2018.


Reply to 'Hormone use missing from UK Biobank cardiovascular disease study'.

Peters SAE, Woodward M.

Heart. 2018 Jul;104(14):1225-1226. doi: 10.1136/heartjnl-2018-313141. No abstract available.


Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota.

Edogawa S, Peters SA, Jenkins GD, Gurunathan SV, Sundt WJ, Johnson S, Lennon RJ, Dyer RB, Camilleri M, Kashyap PC, Farrugia G, Chen J, Singh RJ, Grover M.

FASEB J. 2018 Jun 13:fj201800560R. doi: 10.1096/fj.201800560R. [Epub ahead of print]


DNA sequence and shape are predictive for meiotic crossovers throughout the plant kingdom.

Demirci S, Peters SA, de Ridder D, van Dijk ADJ.

Plant J. 2018 May 29. doi: 10.1111/tpj.13979. [Epub ahead of print]


Sex differences in macronutrient intake and adherence to dietary recommendations: findings from the UK Biobank.

Bennett E, Peters SAE, Woodward M.

BMJ Open. 2018 Apr 24;8(4):e020017. doi: 10.1136/bmjopen-2017-020017.


Sex Differences in High-Intensity Statin Use Following Myocardial Infarction in the United States.

Peters SAE, Colantonio LD, Zhao H, Bittner V, Dai Y, Farkouh ME, Monda KL, Safford MM, Muntner P, Woodward M.

J Am Coll Cardiol. 2018 Apr 24;71(16):1729-1737. doi: 10.1016/j.jacc.2018.02.032.


Sex Differences in the Burden and Complications of Diabetes.

Peters SAE, Woodward M.

Curr Diab Rep. 2018 Apr 18;18(6):33. doi: 10.1007/s11892-018-1005-5. Review.


Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration.

Peters SAE, Wang X, Lam TH, Kim HC, Ho S, Ninomiya T, Knuiman M, Vaartjes I, Bots ML, Woodward M; Asia Pacific Cohort Studies Collaboration.

BMJ Open. 2018 Mar 6;8(3):e019335. doi: 10.1136/bmjopen-2017-019335.


Sex Differences in the Association Between Measures of General and Central Adiposity and the Risk of Myocardial Infarction: Results From the UK Biobank.

Peters SAE, Bots SH, Woodward M.

J Am Heart Assoc. 2018 Feb 28;7(5). pii: e008507. doi: 10.1161/JAHA.117.008507.


Women's reproductive factors and incident cardiovascular disease in the UK Biobank.

Peters SA, Woodward M.

Heart. 2018 Jul;104(13):1069-1075. doi: 10.1136/heartjnl-2017-312289. Epub 2018 Jan 15.


Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective.

Shebley M, Sandhu P, Emami Riedmaier A, Jamei M, Narayanan R, Patel A, Peters SA, Reddy VP, Zheng M, de Zwart L, Beneton M, Bouzom F, Chen J, Chen Y, Cleary Y, Collins C, Dickinson GL, Djebli N, Einolf HJ, Gardner I, Huth F, Kazmi F, Khalil F, Lin J, Odinecs A, Patel C, Rong H, Schuck E, Sharma P, Wu SP, Xu Y, Yamazaki S, Yoshida K, Rowland M.

Clin Pharmacol Ther. 2018 Jul;104(1):88-110. doi: 10.1002/cpt.1013. Epub 2018 Feb 2. Review.


Sex differences in risk factor management of coronary heart disease across three regions.

Zhao M, Vaartjes I, Graham I, Grobbee D, Spiering W, Klipstein-Grobusch K, Woodward M, Peters SA.

Heart. 2017 Oct;103(20):1587-1594. doi: 10.1136/heartjnl-2017-311429. Epub 2017 Sep 20.


Twenty-Year Predictors of Peripheral Arterial Disease Compared With Coronary Heart Disease in the Scottish Heart Health Extended Cohort (SHHEC).

Tunstall-Pedoe H, Peters SAE, Woodward M, Struthers AD, Belch JJF.

J Am Heart Assoc. 2017 Sep 18;6(9). pii: e005967. doi: 10.1161/JAHA.117.005967. Erratum in: J Am Heart Assoc. 2017 Dec 23;6(12):e004215.


Pregnancy, pregnancy loss, and the risk of cardiovascular disease in Chinese women: findings from the China Kadoorie Biobank.

Peters SAE, Yang L, Guo Y, Chen Y, Bian Z, Tian X, Chang L, Zhang S, Liu J, Wang T, Chen J, Li L, Woodward M, Chen Z; China Kadoorie Biobank collaboration group.

BMC Med. 2017 Aug 8;15(1):148. doi: 10.1186/s12916-017-0912-7.


Identification of methylated GnTI-dependent N-glycans in Botryococcus brauni.

Schulze S, Urzica E, Reijnders MJMF, van de Geest H, Warris S, Bakker LV, Fufezan C, Martins Dos Santos VAP, Schaap PJ, Peters SA, Hippler M.

New Phytol. 2017 Sep;215(4):1361-1369. doi: 10.1111/nph.14713. Epub 2017 Jul 24.


Incorporating Added Sugar Improves the Performance of the Health Star Rating Front-of-Pack Labelling System in Australia.

Peters SAE, Dunford E, Jones A, Ni Mhurchu C, Crino M, Taylor F, Woodward M, Neal B.

Nutrients. 2017 Jul 5;9(7). pii: E701. doi: 10.3390/nu9070701.


Breastfeeding and the Risk of Maternal Cardiovascular Disease: A Prospective Study of 300 000 Chinese Women.

Peters SAE, Yang L, Guo Y, Chen Y, Bian Z, Du J, Yang J, Li S, Li L, Woodward M, Chen Z.

J Am Heart Assoc. 2017 Jun 21;6(6). pii: e006081. doi: 10.1161/JAHA.117.006081.


Age at Menarche and Incidence of Diabetes: A Prospective Study of 300,000 Women in China.

Yang L, Li L, Peters SAE, Clarke R, Guo Y, Chen Y, Bian Z, Sherliker P, Yin J, Tang Z, Wang C, Wang X, Zhang L, Woodward M, Chen Z.

Am J Epidemiol. 2018 Feb 1;187(2):190-198. doi: 10.1093/aje/kwx219.


Sex differences in coronary heart disease and stroke mortality: a global assessment of the effect of ageing between 1980 and 2010.

Bots SH, Peters SAE, Woodward M.

BMJ Glob Health. 2017 Mar 27;2(2):e000298. doi: 10.1136/bmjgh-2017-000298. eCollection 2017.


Women's health: a new global agenda.

Peters SAE, Woodward M, Jha V, Kennedy S, Norton R.

BMJ Glob Health. 2016 Nov 1;1(3):e000080. doi: 10.1136/bmjgh-2016-000080. eCollection 2016.


The Sodium Content of Processed Foods in South Africa during the Introduction of Mandatory Sodium Limits.

Peters SAE, Dunford E, Ware LJ, Harris T, Walker A, Wicks M, van Zyl T, Swanepoel B, Charlton KE, Woodward M, Webster J, Neal B.

Nutrients. 2017 Apr 20;9(4). pii: E404. doi: 10.3390/nu9040404.

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