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Items: 29


The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.

Dong X, Leksa NC, Chhabra ES, Arndt JW, Lu Q, Knockenhauer KE, Peters RT, Springer TA.

Blood. 2019 Apr 4;133(14):1523-1533. doi: 10.1182/blood-2018-10-876300. Epub 2019 Jan 14.


Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarization.

Kis-Toth K, Rajani GM, Simpson A, Henry KL, Dumont J, Peters RT, Salas J, Loh C.

Blood Adv. 2018 Nov 13;2(21):2904-2916. doi: 10.1182/bloodadvances.2018024497.


Management of suspected thyroglossal duct cysts.

Povey HG, Selvachandran H, Peters RT, Jones MO.

J Pediatr Surg. 2018 Feb;53(2):281-282. doi: 10.1016/j.jpedsurg.2017.11.019. Epub 2017 Nov 13.


Mortality and morbidity in oesophageal atresia.

Peters RT, Ragab H, Columb MO, Bruce J, MacKinnon RJ, Craigie RJ.

Pediatr Surg Int. 2017 Sep;33(9):989-994. doi: 10.1007/s00383-017-4124-1. Epub 2017 Jul 12.


Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype.

Driessler F, Miguelino MG, Pierce GF, Peters RT, Sommer JM.

Blood Coagul Fibrinolysis. 2017 Oct;28(7):540-550. doi: 10.1097/MBC.0000000000000638.


The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein.

Leksa NC, Chiu PL, Bou-Assaf GM, Quan C, Liu Z, Goodman AB, Chambers MG, Tsutakawa SE, Hammel M, Peters RT, Walz T, Kulman JD.

J Thromb Haemost. 2017 Jun;15(6):1167-1179. doi: 10.1111/jth.13700. Epub 2017 May 3.


Recombinant Factor IX Fc Fusion Protein Maintains Full Procoagulant Properties and Exhibits Prolonged Efficacy in Hemophilia B Mice.

Toby GG, Liu T, Buyue Y, Zhang X, Bitonti AJ, Pierce GF, Sommer JM, Jiang H, Peters RT.

PLoS One. 2016 Feb 3;11(2):e0148255. doi: 10.1371/journal.pone.0148255. eCollection 2016.


Extension of in vivo half-life of biologically active molecules by XTEN protein polymers.

Podust VN, Balan S, Sim BC, Coyle MP, Ernst U, Peters RT, Schellenberger V.

J Control Release. 2016 Oct 28;240:52-66. doi: 10.1016/j.jconrel.2015.10.038. Epub 2015 Oct 30. Review.


Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry.

Chiu PL, Bou-Assaf GM, Chhabra ES, Chambers MG, Peters RT, Kulman JD, Walz T.

Blood. 2015 Aug 20;126(8):935-8. doi: 10.1182/blood-2015-04-641688. Epub 2015 Jun 11.


A single chain variant of factor VIII Fc fusion protein retains normal in vivo efficacy but exhibits altered in vitro activity.

Buyue Y, Liu T, Kulman JD, Toby GG, Kamphaus GD, Patarroyo-White S, Lu Q, Reidy TJ, Mei B, Jiang H, Pierce GF, Sommer JM, Peters RT.

PLoS One. 2014 Nov 21;9(11):e113600. doi: 10.1371/journal.pone.0113600. eCollection 2014.


Congenital infantile fibrosarcoma of the colon: a case series and literature review.

Parmar V, Peters RT, Cheesman E, Edi-Osagie N, Craigie RJ.

Pediatr Surg Int. 2014 Oct;30(10):1079-85. doi: 10.1007/s00383-014-3589-4. Epub 2014 Aug 24. Review.


Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity.

Sommer JM, Buyue Y, Bardan S, Peters RT, Jiang H, Kamphaus GD, Gray E, Pierce GF.

Thromb Haemost. 2014 Nov;112(5):932-40. doi: 10.1160/TH13-11-0971. Epub 2014 Aug 21.


Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics.

Rath T, Baker K, Dumont JA, Peters RT, Jiang H, Qiao SW, Lencer WI, Pierce GF, Blumberg RS.

Crit Rev Biotechnol. 2015 Jun;35(2):235-54. doi: 10.3109/07388551.2013.834293. Epub 2013 Oct 24. Review.


Morbidity and mortality in total esophagogastric dissociation: a systematic review.

Peters RT, Goh YL, Veitch JM, Khalil BA, Morabito A.

J Pediatr Surg. 2013 Apr;48(4):707-12. doi: 10.1016/j.jpedsurg.2012.11.049. Review.


Congenital lung malformations: an ongoing controversy.

Peters RT, Burge DM, Marven SS.

Ann R Coll Surg Engl. 2013 Mar;95(2):144-7. doi: 10.1308/003588412X13373405387735.


Biochemical and functional characterization of a recombinant monomeric factor VIII-Fc fusion protein.

Peters RT, Toby G, Lu Q, Liu T, Kulman JD, Low SC, Bitonti AJ, Pierce GF.

J Thromb Haemost. 2013 Jan;11(1):132-41. doi: 10.1111/jth.12076.


Pneumonectomy: The final cut in a rare incidence of persistent bronchopleural fistula following empyema.

Peters RT, Child F, Long AM, Humphrey GM, Rakoczy G.

Pediatr Pulmonol. 2013 Jun;48(6):617-21. doi: 10.1002/ppul.22649. Epub 2012 Aug 21.


Treat the patient not the X-ray!

Peters RT, Rakoczy G.

Pediatr Int. 2012 Aug;54(4):569-70. doi: 10.1111/j.1442-200X.2012.03640.x. No abstract available.


Atrial natriuretic peptide-Fc, ANP-Fc, fusion proteins: semisynthesis, in vitro activity and pharmacokinetics in rats.

Mezo AR, McDonnell KA, Low SC, Song J, Reidy TJ, Lu Q, Amari JV, Hoehn T, Peters RT, Dumont J, Bitonti AJ.

Bioconjug Chem. 2012 Mar 21;23(3):518-26. doi: 10.1021/bc200592c. Epub 2012 Feb 14.


Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.

Shapiro AD, Ragni MV, Valentino LA, Key NS, Josephson NC, Powell JS, Cheng G, Thompson AR, Goyal J, Tubridy KL, Peters RT, Dumont JA, Euwart D, Li L, Hallén B, Gozzi P, Bitonti AJ, Jiang H, Luk A, Pierce GF.

Blood. 2012 Jan 19;119(3):666-72. doi: 10.1182/blood-2011-07-367003. Epub 2011 Nov 22.


Gastrostomy complications in infants and children: a comparative study.

Peters RT, Balduyck B, Nour S.

Pediatr Surg Int. 2010 Jul;26(7):707-9. doi: 10.1007/s00383-010-2612-7. Epub 2010 May 8.


Prolonged activity of factor IX as a monomeric Fc fusion protein.

Peters RT, Low SC, Kamphaus GD, Dumont JA, Amari JV, Lu Q, Zarbis-Papastoitsis G, Reidy TJ, Merricks EP, Nichols TC, Bitonti AJ.

Blood. 2010 Mar 11;115(10):2057-64. doi: 10.1182/blood-2009-08-239665. Epub 2010 Jan 7.


Paediatric circumcision using bipolar diathermy.

Peters RT, Fisher R.

Ann R Coll Surg Engl. 2009 Jul;91(5):436. No abstract available.


Computed tomography in the assessment of suspected large bowel obstruction.

Beattie GC, Peters RT, Guy S, Mendelson RM.

ANZ J Surg. 2007 Mar;77(3):160-5.


Monomeric Fc fusions: impact on pharmacokinetic and biological activity of protein therapeutics.

Dumont JA, Low SC, Peters RT, Bitonti AJ.

BioDrugs. 2006;20(3):151-60. Review.


Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway.

Bitonti AJ, Dumont JA, Low SC, Peters RT, Kropp KE, Palombella VJ, Stattel JM, Lu Y, Tan CA, Song JJ, Garcia AM, Simister NE, Spiekermann GM, Lencer WI, Blumberg RS.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9763-8. Epub 2004 Jun 21.


A new family of IKK-related kinases may function as I kappa B kinase kinases.

Peters RT, Maniatis T.

Biochim Biophys Acta. 2001;1471(2):M57-62. Review. No abstract available.


IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex.

Peters RT, Liao SM, Maniatis T.

Mol Cell. 2000 Mar;5(3):513-22.


MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta.

Lee FS, Peters RT, Dang LC, Maniatis T.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9319-24.

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