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Items: 1 to 50 of 2134

1.

Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives Against Pancreatic Cancer Cells.

Li Petri G, Cascioferro S, El Hassouni B, Carbone D, Parrino B, Cirrincione G, Peters GJ, Diana P, Giovannetti E.

Anticancer Res. 2019 Jul;39(7):3615-3620. doi: 10.21873/anticanres.13509.

PMID:
31262887
2.

Uridine Cytidine Kinase 2 as a Potential Biomarker for Treatment with RX-3117 in Pancreatic Cancer.

El Hassouni B, Infante J, Mantini G, Ricci C, Funel N, Giovannetti E, Peters GJ.

Anticancer Res. 2019 Jul;39(7):3609-3614. doi: 10.21873/anticanres.13508.

PMID:
31262886
3.

From 'Targeted Therapy' to Targeted Therapy.

Peters GJ.

Anticancer Res. 2019 Jul;39(7):3341-3345. doi: 10.21873/anticanres.13476. Review.

PMID:
31262854
4.

To Combine or Not Combine: Drug Interactions and Tools for Their Analysis. Reflections from the EORTC-PAMM Course on Preclinical and Early-phase Clinical Pharmacology.

El Hassouni B, Mantini G, Li Petri G, Capula M, Boyd L, Weinstein HNW, Vallés-Marti A, Kouwenhoven MCM, Giovannetti E, Westerman BA, Peters GJ; EORTC PAMM Group.

Anticancer Res. 2019 Jul;39(7):3303-3309. doi: 10.21873/anticanres.13472. Review.

PMID:
31262850
5.

Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold.

Zalar M, Indrakumar S, Levy CW, Tunnicliffe RB, Peters GHJ, Golovanov AP.

Sci Rep. 2019 Jun 21;9(1):9067. doi: 10.1038/s41598-019-45565-6.

6.

In Situ WAXD and SAXS during Tensile Deformation Of Moulded and Sintered Polyamide 12.

Paolucci F, Govaert L, Peters G.

Polymers (Basel). 2019 Jun 5;11(6). pii: E1001. doi: 10.3390/polym11061001.

7.

Predictors of Recurrent Ischemic Stroke in Patients with Embolic Strokes of Undetermined Source and Effects of Rivaroxaban Versus Aspirin According to Risk Status: The NAVIGATE ESUS Trial.

Hart RG, Veltkamp RC, Sheridan P, Sharma M, Kasner SE, Bangdiwala SI, Ntaios G, Shoamanesh A, Ameriso SF, Toni D, Czlonkowska A, Lindgren A, Hankey GJ, Perera KS, Shuaib A, Coutts SB, Gagliardi RJ, Berkowitz SD, Mundl H, Peters G, Connolly SJ; NAVIGATE ESUS Investigators.

J Stroke Cerebrovasc Dis. 2019 May 31. pii: S1052-3057(19)30234-4. doi: 10.1016/j.jstrokecerebrovasdis.2019.05.014. [Epub ahead of print]

PMID:
31160218
8.

Novel targeted strategies to overcome resistance in small-cell lung cancer: focus on PARP inhibitors and rovalpituzumab tesirine.

Van Den Borg R, Leonetti A, Tiseo M, Giovannetti E, Peters GJ.

Expert Rev Anticancer Ther. 2019 Jun;19(6):461-471. doi: 10.1080/14737140.2019.1624530. Epub 2019 May 31.

PMID:
31148500
9.

The prevalence of Staphylococcus aureus with mucoid phenotype in the airways of patients with cystic fibrosis-A prospective study.

Lennartz FE, Schwartbeck B, Dübbers A, Große-Onnebrink J, Kessler C, Küster P, Schültingkemper H, Peters G, Kahl BC.

Int J Med Microbiol. 2019 Jul;309(5):283-287. doi: 10.1016/j.ijmm.2019.05.002. Epub 2019 May 11.

PMID:
31122879
10.

Application of interpretable artificial neural networks to early monoclonal antibodies development.

Gentiluomo L, Roessner D, Augustijn D, Svilenov H, Kulakova A, Mahapatra S, Winter G, Streicher W, Rinnan Å, Peters GHJ, Harris P, Frieß W.

Eur J Pharm Biopharm. 2019 Aug;141:81-89. doi: 10.1016/j.ejpb.2019.05.017. Epub 2019 May 18.

PMID:
31112768
11.

Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR.

Indrakumar S, Zalar M, Pohl C, Nørgaard A, Streicher W, Harris P, Golovanov AP, Peters GHJ.

J Phys Chem B. 2019 Jun 13;123(23):4867-4877. doi: 10.1021/acs.jpcb.9b02370. Epub 2019 May 31.

PMID:
31099578
12.

Rethinking gut microbiome residency and the Enterobacteriaceae in healthy human adults.

Martinson JNV, Pinkham NV, Peters GW, Cho H, Heng J, Rauch M, Broadaway SC, Walk ST.

ISME J. 2019 May 14. doi: 10.1038/s41396-019-0435-7. [Epub ahead of print]

PMID:
31089259
13.

Combining in Silico Tools with Multicriteria Analysis for Alternatives Assessment of Hazardous Chemicals: A Case Study of Decabromodiphenyl Ether Alternatives.

Zheng Z, Peters GM, Arp HPH, Andersson PL.

Environ Sci Technol. 2019 Jun 4;53(11):6341-6351. doi: 10.1021/acs.est.8b07163. Epub 2019 May 23.

PMID:
31081616
14.

Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line.

Van Der Steen N, Leonetti A, Keller K, Dekker H, Funel N, Lardon F, Ruijtenbeek R, Tiseo M, Rolfo C, Pauwels P, Peters GJ, Giovannetti E.

Biochem Pharmacol. 2019 Aug;166:128-138. doi: 10.1016/j.bcp.2019.05.014. Epub 2019 May 10.

PMID:
31078602
15.

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells.

Firuzi O, Che PP, El Hassouni B, Buijs M, Coppola S, Löhr M, Funel N, Heuchel R, Carnevale I, Schmidt T, Mantini G, Avan A, Saso L, Peters GJ, Giovannetti E.

Cancers (Basel). 2019 May 8;11(5). pii: E638. doi: 10.3390/cancers11050638.

16.

Effect of Thermal History and Shear on the Viscoelastic Response of iPP Containing an Oxalamide-Based Organic Compound.

Wilsens CHRM, Hawke LGD, de Kort GW, Saidi S, Roy M, Leoné N, Hermida-Merino D, Peters GWM, Rastogi S.

Macromolecules. 2019 Apr 9;52(7):2789-2802. doi: 10.1021/acs.macromol.8b02612. Epub 2019 Mar 21.

17.

Structure-Properties Relations for Polyamide 6, Part 2: Influence of Processing Conditions during Injection Moulding on Deformation and Failure Kinetics.

Parodi E, Peters GWM, Govaert LE.

Polymers (Basel). 2018 Jul 16;10(7). pii: E779. doi: 10.3390/polym10070779.

18.
19.

Solution structures of long-acting insulin analogues and their complexes with albumin.

Ryberg LA, Sønderby P, Barrientos F, Bukrinski JT, Peters GHJ, Harris P.

Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):272-282. doi: 10.1107/S2059798318017552. Epub 2019 Feb 26.

PMID:
30950398
20.

Energy- and conformer-dependent excited-state relaxation of an E/Z photoswitchable thienyl-ethene.

Young JD, Honick CR, Zhou J, Pitts CR, Ghorbani F, Peters GM, Lectka T, Tovar JD, Bragg AE.

Phys Chem Chem Phys. 2019 Jul 14;21(26):14440-14452. doi: 10.1039/c9cp01226e. Epub 2019 Mar 28.

PMID:
30920561
21.

RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.

Balboni B, El Hassouni B, Honeywell RJ, Sarkisjan D, Giovannetti E, Poore J, Heaton C, Peterson C, Benaim E, Lee YB, Kim DJ, Peters GJ.

Expert Opin Investig Drugs. 2019 Apr;28(4):311-322. doi: 10.1080/13543784.2019.1583742. Epub 2019 Mar 16. Review.

PMID:
30879349
22.

Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases.

Frigerio B, Bizzoni C, Jansen G, Leamon CP, Peters GJ, Low PS, Matherly LH, Figini M.

J Exp Clin Cancer Res. 2019 Mar 12;38(1):125. doi: 10.1186/s13046-019-1123-1.

23.

Can cytidine deaminase be used as predictive biomarker for gemcitabine toxicity and response?

Peters GJ, Giovannetti E, Honeywell RJ, Ciccolini J.

Br J Clin Pharmacol. 2019 Jun;85(6):1213-1214. doi: 10.1111/bcp.13921. Epub 2019 Apr 23. No abstract available.

24.

Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.

Jaramillo AC, Cloos J, Lemos C, Stam RW, Kaspers GJL, Jansen G, Peters GJ.

Leuk Res. 2019 Apr;79:45-51. doi: 10.1016/j.leukres.2019.02.008. Epub 2019 Feb 23.

PMID:
30849662
25.

E-drug delivery: a futuristic approach.

Yadav KS, Kapse-Mistry S, Peters GJ, Mayur YC.

Drug Discov Today. 2019 Apr;24(4):1023-1030. doi: 10.1016/j.drudis.2019.02.005. Epub 2019 Feb 19. Review.

PMID:
30794860
26.

Progestin therapy to prevent preterm birth: History and effectiveness of current strategies and development of novel approaches.

Mesiano SA, Peters GA, Amini P, Wilson RA, Tochtrop GP, van Den Akker F.

Placenta. 2019 Apr;79:46-52. doi: 10.1016/j.placenta.2019.01.018. Epub 2019 Jan 28. Review.

PMID:
30745115
27.

Authors' reply.

Verhofstadt M, Chambaere K, Thienpont L, Peters GY.

Br J Psychiatry. 2018 Mar;212(3):183-184. doi: 10.1192/bjp.2018.17. No abstract available.

PMID:
30741143
28.

Authors' reply.

Verhofstadt M, Chambaere K, Audenaert K, Thienpont L, Peters GY.

Br J Psychiatry. 2018 Apr;212(4):248. doi: 10.1192/bjp.2018.48. No abstract available.

PMID:
30741139
29.

Best Practices From the APDR: Improving Medical Student Exposure to Interventional Radiology.

Goldman DT, Peters GL, Fischman AM, Vatakencherry GG, Bream PR Jr, Martin JG, Newsome JM, Bercu ZL, Schacht MA, Johnson KS, Milburn JM, Ong S, Kalia V, England E, Heitkamp DE.

Acad Radiol. 2018 Jun;25(6):789-791. doi: 10.1016/j.acra.2017.11.021. Epub 2018 Jan 19. No abstract available.

PMID:
30691774
30.

Migraine overview and summary of current and emerging treatment options.

Peters GL.

Am J Manag Care. 2019 Jan;25(2 Suppl):S23-S34.

31.

Pendant Photochromic Conjugated Polymers Incorporating a Highly Functionalizable Thieno[3,4- b]thiophene Switching Motif.

Peters GM, Tovar JD.

J Am Chem Soc. 2019 Feb 20;141(7):3146-3152. doi: 10.1021/jacs.8b12617. Epub 2019 Feb 6.

PMID:
30672284
32.

DNA methyltransferases expression in normal tissues and various human cancer cell lines, xenografts and tumors.

Honeywell RJ, Sarkisjan D, Kristensen MH, de Klerk DJ, Peters GJ.

Nucleosides Nucleotides Nucleic Acids. 2018;37(12):696-708. doi: 10.1080/15257770.2018.1498516. Epub 2019 Jan 19.

PMID:
30663502
33.

Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.

Peters GJ.

Nucleosides Nucleotides Nucleic Acids. 2018;37(12):666-678. doi: 10.1080/15257770.2018.1508692. Epub 2019 Jan 19.

PMID:
30663496
34.

Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors.

Rovithi M, Gerritse SL, Honeywell RJ, Ten Tije AJ, Ruijter R, Peters GJ, Voortman J, Labots M, Verheul HMW.

J Clin Oncol. 2019 Feb 10;37(5):411-418. doi: 10.1200/JCO.18.00725. Epub 2018 Dec 26.

35.

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.

Sciarrillo R, Wojtuszkiewicz A, El Hassouni B, Funel N, Gandellini P, Lagerweij T, Buonamici S, Blijlevens M, Zeeuw van der Laan EA, Zaffaroni N, Deraco M, Kusamura S, Würdinger T, Peters GJ, Molthoff CFM, Jansen G, Kaspers GJL, Cloos J, Giovannetti E.

EBioMedicine. 2019 Jan;39:215-225. doi: 10.1016/j.ebiom.2018.12.025. Epub 2018 Dec 20.

36.

Systematic literature review on which maternal alcohol behaviours are related to fetal alcohol spectrum disorders (FASD).

Roozen S, Peters GY, Kok G, Townend D, Nijhuis J, Koek G, Curfs L.

BMJ Open. 2018 Dec 19;8(12):e022578. doi: 10.1136/bmjopen-2018-022578.

37.

Self-Interaction of Human Serum Albumin: A Formulation Perspective.

Sønderby P, Bukrinski JT, Hebditch M, Peters GHJ, Curtis RA, Harris P.

ACS Omega. 2018 Nov 30;3(11):16105-16117. doi: 10.1021/acsomega.8b02245. Epub 2018 Nov 28.

38.

Bactericidal activity of bacteriophage endolysin HY-133 against Staphylococcus aureus in comparison to other antibiotics as determined by minimum bactericidal concentrations and time-kill analysis.

Knaack D, Idelevich EA, Schleimer N, Molinaro S, Kriegeskorte A, Peters G, Becker K.

Diagn Microbiol Infect Dis. 2019 Apr;93(4):362-368. doi: 10.1016/j.diagmicrobio.2018.11.005. Epub 2018 Nov 20.

PMID:
30554844
39.

Transporter and Lysosomal Mediated (Multi)drug Resistance to Tyrosine Kinase Inhibitors and Potential Strategies to Overcome Resistance.

de Klerk DJ, Honeywell RJ, Jansen G, Peters GJ.

Cancers (Basel). 2018 Dec 10;10(12). pii: E503. doi: 10.3390/cancers10120503. Review.

40.

Emissions are still rising: ramp up the cuts.

Figueres C, Le Quéré C, Mahindra A, Bäte O, Whiteman G, Peters G, Guan D.

Nature. 2018 Dec;564(7734):27-30. doi: 10.1038/d41586-018-07585-6. No abstract available.

PMID:
30518903
41.

Targeting the ribosome biogenesis key molecule fibrillarin to avoid chemoresistance.

El Hassouni B, Sarkisjan D, Vos JC, Giovannetti E, Peters GJ.

Curr Med Chem. 2018 Dec 3. doi: 10.2174/0929867326666181203133332. [Epub ahead of print]

PMID:
30501594
42.

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients.

Willmann S, Zhang L, Mayer H, Siegmund HU, Tanigawa T, Kaneko M, Peters G, Weitz JI, Berkowitz SD, Burghaus R.

Blood Adv. 2018 Nov 27;2(22):3193-3195. doi: 10.1182/bloodadvances.2018027078. No abstract available.

43.

Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study.

Tibaldi C, Camerini A, Tiseo M, Mazzoni F, Barbieri F, Vittimberga I, Brighenti M, Boni L, Baldini E, Gilli A, Honeywell R, Chartoire M, Peters GJ, Giovannetti E; Italian Oncological Group of Clinical Research (GOIRC).

Br J Cancer. 2018 Nov;119(11):1326-1331. doi: 10.1038/s41416-018-0307-3. Epub 2018 Nov 8.

PMID:
30405211
44.

Serine integrase recombinational engineering (SIRE): A versatile toolbox for genome editing.

Snoeck N, De Mol ML, Van Herpe D, Goormans A, Maryns I, Coussement P, Peters G, Beauprez J, De Maeseneire SL, Soetaert W.

Biotechnol Bioeng. 2019 Feb;116(2):364-374. doi: 10.1002/bit.26854. Epub 2018 Nov 15.

PMID:
30345503
45.

Structural Changes in Provincial Emission Transfers within China.

Pan C, Peters GP, Andrew RM, Korsbakken JI, Li S, Zhou P, Zhou D.

Environ Sci Technol. 2018 Nov 20;52(22):12958-12967. doi: 10.1021/acs.est.8b03424. Epub 2018 Nov 5.

PMID:
30339021
46.

Controlling Structure Beyond the Initial Coordination Sphere: Complexation-Induced Reversed Micelle Formation in Calix[4]pyrrole-Containing Diblock Copolymers.

Chi X, Peters GM, Brockman C, Lynch VM, Sessler JL.

J Am Chem Soc. 2018 Oct 17;140(41):13219-13222. doi: 10.1021/jacs.8b09620. Epub 2018 Oct 9.

PMID:
30296081
47.

The State of Medical Student Teaching of Interventional Radiology: Implications for the Future.

Goldman DT, Magnowski A, Rochon PJ, Bream PR Jr, Kondo KL, Peters G, Martin JG, Fischman AM.

J Am Coll Radiol. 2018 Dec;15(12):1761-1764. doi: 10.1016/j.jacr.2018.07.016. Epub 2018 Sep 21.

PMID:
30245218
48.

Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies.

Schaumburg F, Witten A, Flamen A, Stoll M, Alabi AS, Kremsner PG, Löffler B, Zipfel PF, Velavan TP, Peters G.

Clin Infect Dis. 2019 Feb 15;68(5):854-856. doi: 10.1093/cid/ciy666.

PMID:
30192927
49.

Exosite 1 thrombin inhibition with JNJ-64179375 inhibits thrombus formation in a human translational model of thrombosis.

Wilson SJ, Connolly TM, Peters G, Ghosh A, Johnson M, Newby DE.

Cardiovasc Res. 2019 Mar 1;115(3):669-677. doi: 10.1093/cvr/cvy227.

50.

The Energy-Coupling Factor Transporter Module EcfAA'T, a Novel Candidate for the Genetic Basis of Fatty Acid-Auxotrophic Small-Colony Variants of Staphylococcus aureus.

Schleimer N, Kaspar U, Drescher M, Seggewiß J, von Eiff C, Proctor RA, Peters G, Kriegeskorte A, Becker K.

Front Microbiol. 2018 Aug 14;9:1863. doi: 10.3389/fmicb.2018.01863. eCollection 2018.

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