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Items: 18

1.

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium.

Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R.

Nat Commun. 2019 Aug 8;10(1):3577. doi: 10.1038/s41467-019-11423-2.

2.

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells.

Monteiro R, Pinheiro P, Joseph N, Peterkin T, Koth J, Repapi E, Bonkhofer F, Kirmizitas A, Patient R.

Dev Cell. 2016 Aug 22;38(4):358-70. doi: 10.1016/j.devcel.2016.06.024. Epub 2016 Aug 4.

3.

Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors.

Short S, Peterkin T, Guille M, Patient R, Sharpe C.

Open Biol. 2015 Aug;5(8). pii: 150063. doi: 10.1098/rsob.150063.

4.

FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway.

Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R.

Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588.

5.

A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.

Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM.

Cancer Cell. 2013 Aug 12;24(2):229-41. doi: 10.1016/j.ccr.2013.06.004. Epub 2013 Jul 18.

6.

Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency.

Qian W, Chen JJ, Human J, Aya T, Zhu J, Biswas K, Peterkin T, Hungate RW, Arik L, Johnson E, Kumar G, Joseph S, Jona J, Guo HX, Wu Z.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1061-7. doi: 10.1016/j.bmcl.2011.11.112. Epub 2011 Dec 8.

PMID:
22197141
7.

Chromenones as potent bradykinin B1 antagonists.

Bryan MC, Biswas K, Peterkin TA, Rzasa RM, Arik L, Lehto SG, Sun H, Hsieh FY, Xu C, Fremeau RT, Allen JR.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):619-22. doi: 10.1016/j.bmcl.2011.10.068. Epub 2011 Oct 28.

PMID:
22088753
8.

Discovery of potent, orally bioavailable phthalazinone bradykinin B1 receptor antagonists.

Biswas K, Peterkin TA, Bryan MC, Arik L, Lehto SG, Sun H, Hsieh FY, Xu C, Fremeau RT, Allen JR.

J Med Chem. 2011 Oct 27;54(20):7232-46. doi: 10.1021/jm200808v. Epub 2011 Sep 26.

PMID:
21902230
9.

Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators.

Simões FC, Peterkin T, Patient R.

Development. 2011 Aug;138(15):3235-45. doi: 10.1242/dev.059634.

10.

3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation.

Chen JJ, Nguyen T, D'Amico DC, Qian W, Human J, Aya T, Biswas K, Fotsch C, Han N, Liu Q, Nishimura N, Peterkin TA, Yang K, Zhu J, Riahi BB, Hungate RW, Andersen NG, Colyer JT, Faul MM, Kamassah A, Wang J, Jona J, Kumar G, Johnson E, Askew BC.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3384-9. doi: 10.1016/j.bmcl.2011.03.115. Epub 2011 Apr 7.

PMID:
21514825
11.

Cardiopoietic factors: extracellular signals for cardiac lineage commitment.

Noseda M, Peterkin T, Simões FC, Patient R, Schneider MD.

Circ Res. 2011 Jan 7;108(1):129-52. doi: 10.1161/CIRCRESAHA.110.223792.

12.

Common genetic control of haemangioblast and cardiac development in zebrafish.

Peterkin T, Gibson A, Patient R.

Development. 2009 May;136(9):1465-74. doi: 10.1242/dev.032748. Epub 2009 Mar 18.

13.

Aryl sulfones as novel bradykinin B1 receptor antagonists for treatment of chronic pain.

Biswas K, Aya T, Qian W, Peterkin TA, Chen JJ, Human J, Hungate RW, Kumar G, Arik L, Lester-Zeiner D, Biddlecome G, Manning BH, Sun H, Dong H, Huang M, Loeloff R, Johnson EJ, Askew BC.

Bioorg Med Chem Lett. 2008 Sep 1;18(17):4764-9. doi: 10.1016/j.bmcl.2008.07.108. Epub 2008 Jul 31.

PMID:
18706809
14.

Discovery of novel hydroxy-thiazoles as HIF-alpha prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation.

Tegley CM, Viswanadhan VN, Biswas K, Frohn MJ, Peterkin TA, Chang C, Bürli RW, Dao JH, Veith H, Rogers N, Yoder SC, Biddlecome G, Tagari P, Allen JR, Hungate RW.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):3925-8. doi: 10.1016/j.bmcl.2008.06.031. Epub 2008 Jun 13.

PMID:
18579373
15.

Redundancy and evolution of GATA factor requirements in development of the myocardium.

Peterkin T, Gibson A, Patient R.

Dev Biol. 2007 Nov 15;311(2):623-35. Epub 2007 Aug 16.

16.

The roles of GATA-4, -5 and -6 in vertebrate heart development.

Peterkin T, Gibson A, Loose M, Patient R.

Semin Cell Dev Biol. 2005 Feb;16(1):83-94. Epub 2004 Dec 15. Review.

PMID:
15659343
17.

GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation.

Peterkin T, Gibson A, Patient R.

EMBO J. 2003 Aug 15;22(16):4260-73.

18.

RNA-dependent cytoplasmic anchoring of a transcription factor subunit during Xenopus development.

Brzostowski J, Robinson C, Orford R, Elgar S, Scarlett G, Peterkin T, Malartre M, Kneale G, Wormington M, Guille M.

EMBO J. 2000 Jul 17;19(14):3683-93.

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