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Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System.

Marín Morales JM, Münch N, Peter K, Freund D, Oelschlägel U, Hölig K, Böhm T, Flach AC, Keßler J, Bonifacio E, Bornhäuser M, Fuchs A.

Front Immunol. 2019 Feb 1;10:38. doi: 10.3389/fimmu.2019.00038. eCollection 2019.


Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA.

Michel T, Link A, Abraham MK, Schlensak C, Peter K, Wendel HP, Wang X, Krajewski S.

J Vis Exp. 2019 Feb 1;(144). doi: 10.3791/58444.


Opioids and ST Elevation Myocardial Infarction: A Systematic Review.

Koh JQS, Fernando H, Peter K, Stub D.

Heart Lung Circ. 2019 Feb 1. pii: S1443-9506(19)30037-X. doi: 10.1016/j.hlc.2018.12.015. [Epub ahead of print] Review.


D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells.

Ugele I, Cárdenas-Conejo ZE, Hammon K, Wehrstein M, Bruss C, Peter K, Singer K, Gottfried E, Boesch J, Oefner P, Dettmer K, Renner K, Kreutz M.

Int J Mol Sci. 2019 Feb 10;20(3). pii: E742. doi: 10.3390/ijms20030742.


Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis: A Preclinical Pilot Study.

Granja T, Körner A, Glück C, Hohmann JD, Wang X, Köhler D, Streißenberger A, Nandurkar HH, Mirakaj V, Rosenberger P, Peter K, Straub A.

Crit Care Med. 2019 Feb 5. doi: 10.1097/CCM.0000000000003682. [Epub ahead of print]


Platelet Depletion is Effective in Ameliorating Anxiety-Like Behavior and Reducing the Pro-Inflammatory Environment in the Hippocampus in Murine Experimental Autoimmune Encephalomyelitis.

Kocovski P, Jiang X, D'Souza CS, Li Z, Dang PT, Wang X, Chen W, Peter K, Hale MW, Orian JM.

J Clin Med. 2019 Feb 1;8(2). pii: E162. doi: 10.3390/jcm8020162.


Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients.

Zaldivia MTK, Hering D, Marusic P, Sata Y, Lee R, Esler MD, Htun NM, Duval J, Hammond L, Flierl U, Wang X, Drummond GR, Walton A, Gardiner EE, Andrews RK, Schlaich MP, Peter K.

Cardiovasc Res. 2019 Feb 4. doi: 10.1093/cvr/cvz033. [Epub ahead of print]


Whole-genome comparisons of Penicillium spp. reveals secondary metabolic gene clusters and candidate genes associated with fungal aggressiveness during apple fruit decay.

Wu G, Jurick Ii WM, Lichtner FJ, Peng H, Yin G, Gaskins VL, Yin Y, Hua SS, Peter KA, Bennett JW.

PeerJ. 2019 Jan 9;7:e6170. doi: 10.7717/peerj.6170. eCollection 2019.


Impact of single-room contact precautions on hospital-acquisition and transmission of multidrug-resistant Escherichia coli: a prospective multicentre cohort study in haematological and oncological wards.

Biehl LM, Higgins P, Wille T, Peter K, Hamprecht A, Peter S, Dörfel D, Vogel W, Häfner H, Lemmen S, Panse J, Rohde H, Klupp EM, Schafhausen P, Imirzalioglu C, Falgenhauer L, Salmanton-García J, Stecher M, Vehreschild JJ, Seifert H, Vehreschild MJGT.

Clin Microbiol Infect. 2019 Jan 12. pii: S1198-743X(18)30840-1. doi: 10.1016/j.cmi.2018.12.029. [Epub ahead of print]


What matters in Cardiovascular Research? Scientific discovery driving clinical delivery.

Guzik TJ, Antoniades C, Baker AH, Harrison DG, Loughrey CM, Maffia P, Murphy E, Nicklin SA, Peter K, Pearson J, Casadei B.

Cardiovasc Res. 2018 Oct 1;114(12):1565-1568. doi: 10.1093/cvr/cvy214. No abstract available.


Baseline Sensitivity of Penicillium spp. to Difenoconazole.

Jurick WM 2nd, Macarisin O, Gaskins VL, Janisiewicz WJ, Peter KA, Cox KD.

Plant Dis. 2019 Feb;103(2):331-337. doi: 10.1094/PDIS-05-18-0860-RE. Epub 2018 Dec 18.


Evaluating emerging organic contaminant removal in an engineered hyporheic zone using high resolution mass spectrometry.

Peter KT, Herzog S, Tian Z, Wu C, McCray JE, Lynch K, Kolodziej EP.

Water Res. 2019 Mar 1;150:140-152. doi: 10.1016/j.watres.2018.11.050. Epub 2018 Nov 23.


Platelets in the Pathogenesis of Vascular Disease and their Role as a Therapeutic Target.

Prabhu S, Sharma R, Peter K.

In: Fitridge R, Thompson M, editors. Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists [Internet]. Adelaide (AU): University of Adelaide Press; 2011. No abstract available. 11.


Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.

Renner K, Seilbeck A, Kauer N, Ugele I, Siska PJ, Brummer C, Bruss C, Decking SM, Fante M, Schmidt A, Hammon K, Singer K, Klobuch S, Thomas S, Gottfried E, Peter K, Kreutz M.

Front Pharmacol. 2018 Nov 2;9:1258. doi: 10.3389/fphar.2018.01258. eCollection 2018.


Automated Measurement and Subtask Analysis of the Timed Upand- Go Test in the Field of Geriatrics.

Andreas Z, Peter K, Robert MO, Gunter S.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1526-1529. doi: 10.1109/EMBC.2018.8512464.


Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage and dysfunction in salt-sensitive hypertension.

Krishnan SM, Ling YH, Huuskes BM, Ferens D, Saini N, Chan CT, Diep H, Kett MM, Samuel CS, Kemp-Harper BK, Robertson AAB, Cooper MA, Peter K, Latz E, Mansell A, Sobey CG, Drummond GR, Vinh A.

Cardiovasc Res. 2018 Oct 24. doi: 10.1093/cvr/cvy252. [Epub ahead of print]


Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque.

Rashid I, Maghzal GJ, Chen YC, Cheng D, Talib J, Newington D, Ren M, Vajandar SK, Searle A, Maluenda A, Lindstedt EL, Jabbour A, Kettle AJ, Bongers A, Power C, Michaëlsson E, Peter K, Stocker R.

Eur Heart J. 2018 Sep 14;39(35):3301-3310. doi: 10.1093/eurheartj/ehy419.


Using High-Resolution Mass Spectrometry to Identify Organic Contaminants Linked to Urban Stormwater Mortality Syndrome in Coho Salmon.

Peter KT, Tian Z, Wu C, Lin P, White S, Du B, McIntyre JK, Scholz NL, Kolodziej EP.

Environ Sci Technol. 2018 Sep 18;52(18):10317-10327. doi: 10.1021/acs.est.8b03287. Epub 2018 Sep 7.


Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.

Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M.

J Biol Chem. 2018 Oct 12;293(41):15947-15961. doi: 10.1074/jbc.RA118.004180. Epub 2018 Aug 29.


The bidirectional interaction between the sympathetic nervous system and immune mechanisms in the pathogenesis of hypertension.

Carnagarin R, Matthews V, Zaldivia MTK, Peter K, Schlaich MP.

Br J Pharmacol. 2018 Aug 20. doi: 10.1111/bph.14481. [Epub ahead of print] Review.


Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis.

Hanjaya-Putra D, Haller C, Wang X, Dai E, Lim B, Liu L, Jaminet P, Yao J, Searle A, Bonnard T, Hagemeyer CE, Peter K, Chaikof EL.

JCI Insight. 2018 Aug 9;3(15). pii: 99329. doi: 10.1172/jci.insight.99329. [Epub ahead of print]


Platelet lipidomics and function: joining the dots.

McFadyen JD, Peter K.

Blood. 2018 Aug 2;132(5):465-466. doi: 10.1182/blood-2018-06-854950. No abstract available.


The pulmonary microvasculature entraps induced vascular progenitor cells (iVPCs) systemically delivered after cardiac ischemia-reperfusion injury: Indication for preservation of heart function via paracrine effects beyond engraftment.

Ziegler M, Haigh K, Nguyen T, Wang X, Lim B, Yap ML, Eddy EM, Haigh JJ, Peter K.

Microcirculation. 2018 Jul 21:e12493. doi: 10.1111/micc.12493. [Epub ahead of print]


Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes.

McFadyen JD, Kiefer J, Braig D, Loseff-Silver J, Potempa LA, Eisenhardt SU, Peter K.

Front Immunol. 2018 Jun 12;9:1351. doi: 10.3389/fimmu.2018.01351. eCollection 2018. Review.


Anti-TIM-1 Monoclonal Antibody (RMT1-10) Attenuates Atherosclerosis By Expanding IgM-producing B1a Cells.

Hosseini H, Yi L, Kanellakis P, Cao A, Tay C, Peter K, Bobik A, Toh BH, Kyaw T.

J Am Heart Assoc. 2018 Jun 23;7(13). pii: e008447. doi: 10.1161/JAHA.117.008447.


Can Predictive Modeling Identify Head and Neck Oncology Patients at Risk for Readmission?

Manning AM, Casper KA, Peter KS, Wilson KM, Mark JR, Collar RM.

Otolaryngol Head Neck Surg. 2018 Oct;159(4):669-674. doi: 10.1177/0194599818775938. Epub 2018 May 22.


The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts.

Diehl P, Gaul DS, Sogl J, Flierl U, Henstridge D, Pahla J, Bugger H, Emmert MY, Ruschitzka F, Bode C, Lüscher TF, Moser M, Matter CM, Peter K, Winnik S.

J Thromb Thrombolysis. 2018 Jul;46(1):102-112. doi: 10.1007/s11239-018-1677-3.


Characterization of a new apple luteovirus identified by high-throughput sequencing.

Liu H, Wu L, Nikolaeva E, Peter K, Liu Z, Mollov D, Cao M, Li R.

Virol J. 2018 May 15;15(1):85. doi: 10.1186/s12985-018-0998-3.


Platelets Drive Inflammation and Target Gray Matter and the Retina in Autoimmune-Mediated Encephalomyelitis.

Sonia D'Souza C, Li Z, Luke Maxwell D, Trusler O, Murphy M, Crewther S, Peter K, Orian JM.

J Neuropathol Exp Neurol. 2018 Jul 1;77(7):567-576. doi: 10.1093/jnen/nly032.


A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury.

Thiele JR, Zeller J, Kiefer J, Braig D, Kreuzaler S, Lenz Y, Potempa LA, Grahammer F, Huber TB, Huber-Lang M, Bannasch H, Stark GB, Peter K, Eisenhardt SU.

Front Immunol. 2018 Apr 16;9:675. doi: 10.3389/fimmu.2018.00675. eCollection 2018.


Dual-Targeted Theranostic Delivery of miRs Arrests Abdominal Aortic Aneurysm Development.

Wang X, Searle AK, Hohmann JD, Liu AL, Abraham MK, Palasubramaniam J, Lim B, Yao Y, Wallert M, Yu E, Chen YC, Peter K.

Mol Ther. 2018 Apr 4;26(4):1056-1065. doi: 10.1016/j.ymthe.2018.02.010. Epub 2018 Feb 16.


Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction.

Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Tewari M, Duerschmied D, Peter K, Bode C, Ahrens I, Hortmann M.

Int J Cardiol. 2018 Apr 15;257:247-254. doi: 10.1016/j.ijcard.2017.10.111.


Ambulatory arterial stiffness index as a predictor of blood pressure response to renal denervation.

Sata Y, Hering D, Head GA, Walton AS, Peter K, Marusic P, Duval J, Lee R, Hammond LJ, Lambert EA, Lambert GW, Esler MD, Schlaich MP.

J Hypertens. 2018 Jun;36(6):1414-1422. doi: 10.1097/HJH.0000000000001682.


A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.

Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc DM, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von Zur Muhlen C, Reinöhl J, Gerhardt T, Plow EF, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A.

Nat Commun. 2018 Feb 6;9(1):525. doi: 10.1038/s41467-018-02896-8.


Current and future antiplatelet therapies: emphasis on preserving haemostasis.

McFadyen JD, Schaff M, Peter K.

Nat Rev Cardiol. 2018 Mar;15(3):181-191. doi: 10.1038/nrcardio.2017.206. Epub 2018 Jan 3. Review.


An Erwinia amylovora yjeK mutant exhibits reduced virulence, increased chemical sensitivity and numerous environmentally dependent proteomic alterations.

Klee SM, Mostafa I, Chen S, Dufresne C, Lehman BL, Sinn JP, Peter KA, McNellis TW.

Mol Plant Pathol. 2018 Jul;19(7):1667-1678. doi: 10.1111/mpp.12650. Epub 2018 Feb 1.


Platelet-Derived Microvesicles in Cardiovascular Diseases.

Zaldivia MTK, McFadyen JD, Lim B, Wang X, Peter K.

Front Cardiovasc Med. 2017 Nov 21;4:74. doi: 10.3389/fcvm.2017.00074. eCollection 2017. Review.


Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients.

Robinson S, Follo M, Haenel D, Mauler M, Stallmann D, Heger LA, Helbing T, Duerschmied D, Peter K, Bode C, Ahrens I, Hortmann M.

Acta Pharmacol Sin. 2018 Jul;39(7):1217-1227. doi: 10.1038/aps.2017.136. Epub 2017 Nov 30.


Mesoscale Nanoparticles: An Unexpected Means for Selective Therapeutic Targeting of Kidney Diseases!

Yap ML, Wang X, Pietersz GA, Peter K.

Hypertension. 2018 Jan;71(1):61-63. doi: 10.1161/HYPERTENSIONAHA.117.09944. Epub 2017 Nov 13. No abstract available.


Circulating HtrA2 after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A potential novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury.

Hortmann M, Robinson S, Mohr M, Haenel D, Mauler M, Laumann R, Stallmann D, Reinoehl J, Duerschmied D, Peter K, Bode C, Ahrens I.

Int J Cardiol. 2017 Dec 15;249:437. doi: 10.1016/j.ijcard.2017.08.022. No abstract available.


CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages.

Samudra AN, Dwyer KM, Selan C, Freddi S, Murray-Segal L, Nikpour M, Hickey MJ, Peter K, Robson SC, Sashindranath M, Cowan PJ, Nandurkar HH.

J Autoimmun. 2018 Mar;88:131-138. doi: 10.1016/j.jaut.2017.10.009. Epub 2017 Nov 3.


A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques.

Maier A, Plaza-Heck P, Meixner F, Guenther F, Kaufmann BA, Kramer M, Heidt T, Zirlik A, Hilgendorf I, Reinöhl J, Stachon P, Bronsert P, Birkemeyer R, Neudorfer I, Peter K, Bode C, von Zur Mühlen C.

Atherosclerosis. 2017 Dec;267:68-77. doi: 10.1016/j.atherosclerosis.2017.10.029. Epub 2017 Oct 24.


Indoxyl 3-sulfate inhibits maturation and activation of human monocyte-derived dendritic cells.

Ghimire S, Matos C, Caioni M, Weber D, Peter K, Holler E, Kreutz M, Renner K.

Immunobiology. 2018 Feb;223(2):239-245. doi: 10.1016/j.imbio.2017.10.014. Epub 2017 Oct 6.


Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.

Günther F, Heidt T, Kramer M, Khanicheh E, Klibanov AL, Geibel-Zehender A, Ferrante EA, Hilgendorf I, Wolf D, Zirlik A, Reinöhl J, Bode C, Peter K, Kaufmann BA, Mühlen CVZ.

Sci Rep. 2017 Nov 2;7(1):14898. doi: 10.1038/s41598-017-15080-7.


Novel Antithrombotic Drugs on the Horizon: The Ultimate Promise to Prevent Clotting While Avoiding Bleeding.

McFadyen JD, Peter K.

Circ Res. 2017 Oct 27;121(10):1133-1135. doi: 10.1161/CIRCRESAHA.117.312012. No abstract available.


Nanoliposomes for Safe and Efficient Therapeutic mRNA Delivery: A Step Toward Nanotheranostics in Inflammatory and Cardiovascular Diseases as well as Cancer.

Abraham MK, Peter K, Michel T, Wendel HP, Krajewski S, Wang X.

Nanotheranostics. 2017 Apr 5;1(2):154-165. doi: 10.7150/ntno.19449. eCollection 2017.


Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides: comment.

Flierl U, Nero TL, Lim B, Andrews RK, Parker MW, Gardiner EE, Peter K.

J Thromb Haemost. 2018 Jan;16(1):181-185. doi: 10.1111/jth.13877. Epub 2017 Nov 16. No abstract available.


Mast Cell: An Unexpected Villain in Venous Thromboembolism?

Huang AL, Bosco JJ, Peter K.

Circ Res. 2017 Sep 29;121(8):899-901. doi: 10.1161/CIRCRESAHA.117.311777. No abstract available.


The association between acute graft-versus-host disease and antimicrobial peptide expression in the gastrointestinal tract after allogeneic stem cell transplantation.

Weber D, Frauenschläger K, Ghimire S, Peter K, Panzer I, Hiergeist A, Weber M, Kutny D, Wolff D, Grube M, Huber E, Oefner P, Gessner A, Hehlgans T, Herr W, Holler E.

PLoS One. 2017 Sep 21;12(9):e0185265. doi: 10.1371/journal.pone.0185265. eCollection 2017.


Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications.

Michel T, Luft D, Abraham MK, Reinhardt S, Salinas Medina ML, Kurz J, Schaller M, Avci-Adali M, Schlensak C, Peter K, Wendel HP, Wang X, Krajewski S.

Mol Ther Nucleic Acids. 2017 Sep 15;8:459-468. doi: 10.1016/j.omtn.2017.07.013. Epub 2017 Jul 25.

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