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Items: 1 to 50 of 353

1.

Cut, copy, move, delete: The study of human interferon genes reveal multiple mechanisms underlying their evolution in amniotes.

Krause CD, Pestka S.

Cytokine. 2015 Dec;76(2):480-495. doi: 10.1016/j.cyto.2015.07.019. Epub 2015 Jul 27.

PMID:
26228976
2.

Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity.

Krause CD, Digioia G, Izotova LS, Xie J, Kim Y, Schwartz BJ, Mirochnitchenko OV, Pestka S.

Cytokine. 2013 Oct;64(1):286-97. doi: 10.1016/j.cyto.2013.06.309. Epub 2013 Jul 3.

3.

Improving the spectral analysis of Fluorescence Resonance Energy Transfer in live cells: application to interferon receptors and Janus kinases.

Krause CD, Digioia G, Izotova LS, Pestka S.

Cytokine. 2013 Oct;64(1):272-85. doi: 10.1016/j.cyto.2013.05.026. Epub 2013 Jun 21.

4.

Analytical use of multi-protein Fluorescence Resonance Energy Transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexes.

Krause CD, Izotova LS, Pestka S.

Cytokine. 2013 Oct;64(1):298-309. doi: 10.1016/j.cyto.2013.05.008. Epub 2013 Jun 13.

5.

Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells.

Wan S, Pestka S, Jubin RG, Lyu YL, Tsai YC, Liu LF.

PLoS One. 2012;7(3):e32542. doi: 10.1371/journal.pone.0032542. Epub 2012 Mar 1.

6.

Interferon-β signaling contributes to Ras transformation.

Tsai YC, Pestka S, Wang LH, Runnels LW, Wan S, Lyu YL, Liu LF.

PLoS One. 2011;6(8):e24291. doi: 10.1371/journal.pone.0024291. Epub 2011 Aug 29.

7.

Binding and activity of all human alpha interferon subtypes.

Lavoie TB, Kalie E, Crisafulli-Cabatu S, Abramovich R, DiGioia G, Moolchan K, Pestka S, Schreiber G.

Cytokine. 2011 Nov;56(2):282-9. doi: 10.1016/j.cyto.2011.07.019.

PMID:
21856167
8.

Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid.

Krause CD, Izotova LS, Ren G, Yuan ZR, Shi Y, Chen CC, Ron Y, Pestka S.

Stem Cell Res Ther. 2011 Mar 14;2(2):15. doi: 10.1186/scrt56.

9.

Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.

Knapinska AM, Gratacós FM, Krause CD, Hernandez K, Jensen AG, Bradley JJ, Wu X, Pestka S, Brewer G.

Mol Cell Biol. 2011 Apr;31(7):1419-31. doi: 10.1128/MCB.00907-10. Epub 2011 Jan 18.

10.

Contamination with recombinant IFN accounts for the unexpected stimulatory properties of commonly used IFN-blocking antibodies.

Moll HP, Freudenthaler H, Zommer A, Buchberger E, Lin XH, Crisafulli S, Pandya Y, Pestka S, Lavoie T, Brostjan C.

Eur J Immunol. 2011 Jan;41(1):252-4. doi: 10.1002/eji.200940145. Epub 2010 Nov 22. No abstract available.

11.

RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes.

Sarkar S, Han J, Sinsimer KS, Liao B, Foster RL, Brewer G, Pestka S.

Mol Cell Biol. 2011 Feb;31(4):602-15. doi: 10.1128/MCB.00835-10. Epub 2010 Dec 6.

12.

AUF1 isoform-specific regulation of anti-inflammatory IL10 expression in monocytes.

Sarkar S, Sinsimer KS, Foster RL, Brewer G, Pestka S.

J Interferon Cytokine Res. 2008 Nov;28(11):679-91. doi: 10.1089/jir.2008.0028.

13.

Interferon protects mice against inhalation anthrax.

Walberg K, Baron S, Poast J, Schwartz B, Izotova L, Pestka S, Peterson JW.

J Interferon Cytokine Res. 2008 Oct;28(10):597-601. doi: 10.1089/jir.2007.0143.

14.

Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay.

Sinsimer KS, Gratacós FM, Knapinska AM, Lu J, Krause CD, Wierzbowski AV, Maher LR, Scrudato S, Rivera YM, Gupta S, Turrin DK, De La Cruz MP, Pestka S, Brewer G.

Mol Cell Biol. 2008 Sep;28(17):5223-37. doi: 10.1128/MCB.00431-08. Epub 2008 Jun 23.

15.

Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase.

Adler V, Bowne W, Michl J, Sookraj KA, Ikram K, Pestka S, Izotova L, Zenilman M, Friedman FK, Qu Y, Pincus MR.

Ann Clin Lab Sci. 2008 Winter;38(1):47-56.

PMID:
18316782
16.

Purification and cloning of interferon alpha.

Pestka S.

Curr Top Microbiol Immunol. 2007;316:23-37. Review.

PMID:
17969442
17.

Historical developments in the research of interferon receptors.

Krause CD, Pestka S.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):473-82. Epub 2007 Aug 10. Review.

PMID:
17693124
18.

The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein.

Qu Y, Adler V, Izotova L, Pestka S, Bowne W, Michl J, Boutjdir M, Friedman FK, Pincus MR.

Front Biosci. 2007 Sep 1;12:5089-97.

PMID:
17569632
19.

The interferons: 50 years after their discovery, there is much more to learn.

Pestka S.

J Biol Chem. 2007 Jul 13;282(28):20047-51. Epub 2007 May 14. Review.

20.

Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.

Krause CD, Yang ZH, Kim YS, Lee JH, Cook JR, Pestka S.

Pharmacol Ther. 2007 Jan;113(1):50-87. Epub 2006 Sep 26. Review.

PMID:
17005254
21.
22.

Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes.

Qu Y, Adler V, Chu T, Platica O, Michl J, Pestka S, Izotova L, Boutjdir M, Pincus MR.

Front Biosci. 2006 Sep 1;11:2420-7.

PMID:
16720323
23.

FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.

Cook JR, Lee JH, Yang ZH, Krause CD, Herth N, Hoffmann R, Pestka S.

Biochem Biophys Res Commun. 2006 Apr 7;342(2):472-81. Epub 2006 Feb 8.

PMID:
16487488
24.

Modulation of the activation of Stat1 by the interferon-gamma receptor complex.

Krause CD, He W, Kotenko S, Pestka S.

Cell Res. 2006 Jan;16(1):113-23.

25.

Preassembly and ligand-induced restructuring of the chains of the IFN-gamma receptor complex: the roles of Jak kinases, Stat1 and the receptor chains.

Krause CD, Lavnikova N, Xie J, Mei E, Mirochnitchenko OV, Jia Y, Hochstrasser RM, Pestka S.

Cell Res. 2006 Jan;16(1):55-69.

26.

Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway.

Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, Saleem A, Nur-E-Kamal A, Liu LF.

Cancer Res. 2006 Jan 15;66(2):921-8.

27.

Interactions among the components of the interleukin-10 receptor complex.

Krause CD, Mei E, Mirochnitchenko O, Lavnikova N, Xie J, Jia Y, Hochstrasser RM, Pestka S.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):377-85. Epub 2005 Dec 13.

PMID:
16364239
28.

Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.

Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR.

Biochemistry. 2005 Aug 16;44(32):10784-95.

PMID:
16086581
29.

Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives.

Krause CD, Pestka S.

Pharmacol Ther. 2005 Jun;106(3):299-346. Epub 2005 Apr 14. Review.

PMID:
15922016
30.

Design and construction of a phosphorylatable chimeric monoclonal antibody with a highly stable phosphate.

Wu W, Kerrigan JE, Yadav P, Schwartz B, Izotova L, Lavoie TB, Pestka S.

Oncol Res. 2004;14(11-12):541-58.

PMID:
15666996
31.

Interferons, interferon-like cytokines, and their receptors.

Pestka S, Krause CD, Walter MR.

Immunol Rev. 2004 Dec;202:8-32. Review.

PMID:
15546383
32.

PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine.

Lee JH, Cook JR, Yang ZH, Mirochnitchenko O, Gunderson SI, Felix AM, Herth N, Hoffmann R, Pestka S.

J Biol Chem. 2005 Feb 4;280(5):3656-64. Epub 2004 Oct 19.

33.

Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically dimethylated at arginine residues in the nucleus.

Miranda TB, Khusial P, Cook JR, Lee JH, Gunderson SI, Pestka S, Zieve GW, Clarke S.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):382-7.

PMID:
15369763
34.

The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.

Logsdon NJ, Jones BC, Allman JC, Izotova L, Schwartz B, Pestka S, Walter MR.

J Mol Biol. 2004 Sep 10;342(2):503-14.

PMID:
15327950
35.

Interleukin-10 and related cytokines and receptors.

Pestka S, Krause CD, Sarkar D, Walter MR, Shi Y, Fisher PB.

Annu Rev Immunol. 2004;22:929-79. Review.

PMID:
15032600
36.

Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.

Kang DC, Gopalkrishnan RV, Lin L, Randolph A, Valerie K, Pestka S, Fisher PB.

Oncogene. 2004 Mar 4;23(9):1789-800.

PMID:
14676839
37.

Increased interleukin-10 mRNA stability in melanoma cells is associated with decreased levels of A + U-rich element binding factor AUF1.

Brewer G, Saccani S, Sarkar S, Lewis A, Pestka S.

J Interferon Cytokine Res. 2003 Oct;23(10):553-64.

PMID:
14585195
39.

A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction.

Chie L, Cook JR, Chung D, Hoffmann R, Yang Z, Kim Y, Pestka S, Pincus MR.

Ann Clin Lab Sci. 2003 Spring;33(2):200-7.

PMID:
12817625
40.

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways.

Sauane M, Gopalkrishnan RV, Lebedeva I, Mei MX, Sarkar D, Su ZZ, Kang DC, Dent P, Pestka S, Fisher PB.

J Cell Physiol. 2003 Aug;196(2):334-45.

PMID:
12811827
41.

MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.

Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Lebedeva IV, Dent P, Pestka S, Fisher PB.

Cytokine Growth Factor Rev. 2003 Feb;14(1):35-51. Review.

PMID:
12485618
42.

Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells.

Krause CD, Mei E, Xie J, Jia Y, Bopp MA, Hochstrasser RM, Pestka S.

Mol Cell Proteomics. 2002 Oct;1(10):805-15.

43.

Site-specific 32P-labeling of cytokines, monoclonal antibodies, and other protein substrates for quantitative assays and therapeutic application.

Clark WA, Izotova L, Philipova D, Wu W, Lin L, Pestka S.

Biotechniques. 2002 Oct;Suppl:76-8, 80-7. Review.

PMID:
12395930
44.

Negative regulation of transcription by the type II arginine methyltransferase PRMT5.

Fabbrizio E, El Messaoudi S, Polanowska J, Paul C, Cook JR, Lee JH, Negre V, Rousset M, Pestka S, Le Cam A, Sardet C.

EMBO Rep. 2002 Jul;3(7):641-5.

45.

Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death.

Bernabei P, Coccia EM, Rigamonti L, Bosticardo M, Forni G, Pestka S, Krause CD, Battistini A, Novelli F.

J Leukoc Biol. 2001 Dec;70(6):950-60.

PMID:
11739558
46.

Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation.

Ding Y, Qin L, Zamarin D, Kotenko SV, Pestka S, Moore KW, Bromberg JS.

J Immunol. 2001 Dec 15;167(12):6884-92.

47.

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.

Huang EY, Madireddi MT, Gopalkrishnan RV, Leszczyniecka M, Su Z, Lebedeva IV, Kang D, Jiang H, Lin JJ, Alexandre D, Chen Y, Vozhilla N, Mei MX, Christiansen KA, Sivo F, Goldstein NI, Mhashilkar AB, Chada S, Huberman E, Pestka S, Fisher PB.

Oncogene. 2001 Oct 25;20(48):7051-63.

48.

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway.

Sarkar S, Pollack BP, Lin KT, Kotenko SV, Cook JR, Lewis A, Pestka S.

J Biol Chem. 2001 Dec 28;276(52):49034-42. Epub 2001 Oct 25.

49.

PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins.

Branscombe TL, Frankel A, Lee JH, Cook JR, Yang Z, Pestka S, Clarke S.

J Biol Chem. 2001 Aug 31;276(35):32971-6. Epub 2001 Jun 18.

50.

Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity.

Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S.

J Immunol. 2001 Jun 15;166(12):7096-103.

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