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Items: 1 to 50 of 251

1.

Correction: Silica-Triggered Autoimmunity in Lupus-Prone Mice Blocked by Docosahexaenoic Acid Consumption.

Bates MA, Brandenberger C, Langohr IM, Kumagai K, Lock AL, Harkema JR, Holian A, Pestka JJ.

PLoS One. 2019 Jul 24;14(7):e0220469. doi: 10.1371/journal.pone.0220469. eCollection 2019.

2.

Correction: Pestka, J.J., et al. Sex Is a Determinant for Deoxynivalenol Metabolism and Elimination in the Mouse. Toxins 2017, 9, 240.

Pestka JJ, Clark ES, Schwartz-Zimmermann HE, Berthiller F.

Toxins (Basel). 2019 Apr 26;11(5). pii: E238. doi: 10.3390/toxins11050238.

3.

Mapping of Dynamic Transcriptome Changes Associated With Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse.

Bates MA, Benninghoff AD, Gilley KN, Holian A, Harkema JR, Pestka JJ.

Front Immunol. 2019 Mar 29;10:632. doi: 10.3389/fimmu.2019.00632. eCollection 2019.

4.

Dietary Docosahexaenoic Acid Prevents Silica-Induced Development of Pulmonary Ectopic Germinal Centers and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse.

Bates MA, Akbari P, Gilley KN, Wagner JG, Li N, Kopec AK, Wierenga KA, Jackson-Humbles D, Brandenberger C, Holian A, Benninghoff AD, Harkema JR, Pestka JJ.

Front Immunol. 2018 Sep 12;9:2002. doi: 10.3389/fimmu.2018.02002. eCollection 2018.

5.

Correction to: Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

Schwartz-Zimmermann HE, Hametner C, Nagl V, Fiby I, Macheiner L, Winkler J, Dänicke S, Clark E, Pestka JJ, Berthiller F.

Arch Toxicol. 2018 Oct;92(10):3245-3246. doi: 10.1007/s00204-018-2273-1.

PMID:
30088018
6.

Sex Is a Determinant for Deoxynivalenol Metabolism and Elimination in the Mouse.

Pestka JJ, Clark ES, Schwartz-Zimmermann HE, Berthiller F.

Toxins (Basel). 2017 Aug 4;9(8). pii: E240. doi: 10.3390/toxins9080240. Erratum in: Toxins (Basel). 2019 Apr 26;11(5):.

7.

Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

Schwartz-Zimmermann HE, Hametner C, Nagl V, Fiby I, Macheiner L, Winkler J, Dänicke S, Clark E, Pestka JJ, Berthiller F.

Arch Toxicol. 2017 Dec;91(12):3857-3872. doi: 10.1007/s00204-017-2012-z. Epub 2017 Jun 21. Erratum in: Arch Toxicol. 2018 Oct;92(10):3245-3246.

8.

Correction: Silica-Triggered Autoimmunity in Lupus-Prone Mice Blocked by Docosahexaenoic Acid Consumption.

Bates MA, Brandenberger C, Langohr IM, Kumagai K, Lock AL, Harkema JR, Holian A, Pestka JJ.

PLoS One. 2017 Feb 6;12(2):e0171877. doi: 10.1371/journal.pone.0171877. eCollection 2017.

9.

Calcium-Sensing Receptor and Transient Receptor Ankyrin-1 Mediate Emesis Induction by Deoxynivalenol (Vomitoxin).

Wu W, Zhou HR, Bursian SJ, Link JE, Pestka JJ.

Toxicol Sci. 2017 Jan;155(1):32-42. doi: 10.1093/toxsci/kfw191. Epub 2016 Sep 25.

10.

Silica-Triggered Autoimmunity in Lupus-Prone Mice Blocked by Docosahexaenoic Acid Consumption.

Bates MA, Brandenberger C, Langohr II, Kumagai K, Lock AL, Harkema JR, Holian A, Pestka JJ.

PLoS One. 2016 Aug 11;11(8):e0160622. doi: 10.1371/journal.pone.0160622. eCollection 2016. Erratum in: PLoS One. 2017 Feb 6;12 (2):e0171877. PLoS One. 2019 Jul 24;14(7):e0220469.

11.

Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology.

Male D, Wu W, Mitchell NJ, Bursian S, Pestka JJ, Wu F.

Food Chem Toxicol. 2016 Aug;94:178-85. doi: 10.1016/j.fct.2016.06.009. Epub 2016 Jun 10.

12.

Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin).

Wu W, Zhou HR, Pestka JJ.

Arch Toxicol. 2017 Jan;91(1):495-507. doi: 10.1007/s00204-016-1687-x. Epub 2016 Mar 15.

PMID:
26979077
13.

High Sensitivity of Aged Mice to Deoxynivalenol (Vomitoxin)-Induced Anorexia Corresponds to Elevated Proinflammatory Cytokine and Satiety Hormone Responses.

Clark ES, Flannery BM, Gardner EM, Pestka JJ.

Toxins (Basel). 2015 Oct 19;7(10):4199-215. doi: 10.3390/toxins7104199.

14.

Murine Anorectic Response to Deoxynivalenol (Vomitoxin) Is Sex-Dependent.

Clark ES, Flannery BM, Pestka JJ.

Toxins (Basel). 2015 Jul 29;7(8):2845-59. doi: 10.3390/toxins7082845.

15.

Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse.

Bates MA, Brandenberger C, Langohr I, Kumagai K, Harkema JR, Holian A, Pestka JJ.

PLoS One. 2015 May 15;10(5):e0125481. doi: 10.1371/journal.pone.0125481. eCollection 2015.

17.

Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations of peptide YY3-36 and 5-hydroxytryptamine.

Wu W, Zhou HR, Bursian SJ, Link JE, Pestka JJ.

Arch Toxicol. 2016 Apr;90(4):997-1007. doi: 10.1007/s00204-015-1508-7. Epub 2015 Apr 9.

PMID:
25855062
19.
20.

Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544.

Wu W, Zhou HR, Bursian SJ, Pan X, Link JE, Berthiller F, Adam G, Krantis A, Durst T, Pestka JJ.

Toxicol Sci. 2014 Nov;142(1):167-81. doi: 10.1093/toxsci/kfu166. Epub 2014 Aug 30.

21.
22.

Effects of oral exposure to naturally-occurring and synthetic deoxynivalenol congeners on proinflammatory cytokine and chemokine mRNA expression in the mouse.

Wu W, He K, Zhou HR, Berthiller F, Adam G, Sugita-Konishi Y, Watanabe M, Krantis A, Durst T, Zhang H, Pestka JJ.

Toxicol Appl Pharmacol. 2014 Jul 15;278(2):107-15. doi: 10.1016/j.taap.2014.04.016. Epub 2014 Apr 29.

23.

Public health impacts of foodborne mycotoxins.

Wu F, Groopman JD, Pestka JJ.

Annu Rev Food Sci Technol. 2014;5:351-72. doi: 10.1146/annurev-food-030713-092431. Epub 2014 Jan 9. Review.

PMID:
24422587
24.

Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.

Wu W, Zhou HR, He K, Pan X, Sugita-Konishi Y, Watanabe M, Zhang H, Pestka JJ.

Toxicol Sci. 2014 Apr;138(2):278-89. doi: 10.1093/toxsci/kft335. Epub 2014 Jan 2.

25.

Dynamic changes in ribosome-associated proteome and phosphoproteome during deoxynivalenol-induced translation inhibition and ribotoxic stress.

Pan X, Whitten DA, Wilkerson CG, Pestka JJ.

Toxicol Sci. 2014 Mar;138(1):217-33. doi: 10.1093/toxsci/kft270. Epub 2013 Nov 27.

26.

Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stress.

Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ.

Toxicol Sci. 2013 Sep;135(1):129-43. doi: 10.1093/toxsci/kft145. Epub 2013 Jun 29.

27.

Deoxynivalenol-induced weight loss in the diet-induced obese mouse is reversible and PKR-independent.

Flannery BM, He K, Pestka JJ.

Toxicol Lett. 2013 Jul 31;221(1):9-14. doi: 10.1016/j.toxlet.2013.05.008. Epub 2013 May 24.

PMID:
23707852
28.

Peptide YY3-36 and 5-hydroxytryptamine mediate emesis induction by trichothecene deoxynivalenol (vomitoxin).

Wu W, Bates MA, Bursian SJ, Flannery B, Zhou HR, Link JE, Zhang H, Pestka JJ.

Toxicol Sci. 2013 May;133(1):186-95. doi: 10.1093/toxsci/kft033. Epub 2013 Mar 1.

29.

Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage.

Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ.

Toxicol Appl Pharmacol. 2013 Apr 15;268(2):201-11. doi: 10.1016/j.taap.2013.01.007. Epub 2013 Jan 23.

30.

Evaluation of insulin-like growth factor acid-labile subunit as a potential biomarker of effect for deoxynivalenol-induced proinflammatory cytokine expression.

Flannery BM, Amuzie CJ, Pestka JJ.

Toxicology. 2013 Feb 8;304:192-8. doi: 10.1016/j.tox.2012.12.017. Epub 2013 Jan 5.

31.

Mechanisms for ribotoxin-induced ribosomal RNA cleavage.

He K, Zhou HR, Pestka JJ.

Toxicol Appl Pharmacol. 2012 Nov 15;265(1):10-8. doi: 10.1016/j.taap.2012.09.017. Epub 2012 Sep 27.

32.

Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.

Wu W, Bates MA, Bursian SJ, Link JE, Flannery BM, Sugita-Konishi Y, Watanabe M, Zhang H, Pestka JJ.

Toxicol Sci. 2013 Jan;131(1):279-91. doi: 10.1093/toxsci/kfs286. Epub 2012 Sep 20.

33.

Modulation of inflammatory gene expression by the ribotoxin deoxynivalenol involves coordinate regulation of the transcriptome and translatome.

He K, Pan X, Zhou HR, Pestka JJ.

Toxicol Sci. 2013 Jan;131(1):153-63. doi: 10.1093/toxsci/kfs266. Epub 2012 Sep 11.

34.

Anorexia induction by the trichothecene deoxynivalenol (vomitoxin) is mediated by the release of the gut satiety hormone peptide YY.

Flannery BM, Clark ES, Pestka JJ.

Toxicol Sci. 2012 Dec;130(2):289-97. doi: 10.1093/toxsci/kfs255. Epub 2012 Aug 17.

35.

Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys.

Carey SA, Plopper CG, Hyde DM, Islam Z, Pestka JJ, Harkema JR.

Toxicol Pathol. 2012 Aug;40(6):887-98. doi: 10.1177/0192623312444028. Epub 2012 May 2.

PMID:
22552393
36.

Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage.

He K, Zhou HR, Pestka JJ.

Toxicol Sci. 2012 Jun;127(2):382-90. doi: 10.1093/toxsci/kfs134. Epub 2012 Apr 5.

37.

Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol.

Wu W, Flannery BM, Sugita-Konishi Y, Watanabe M, Zhang H, Pestka JJ.

Food Chem Toxicol. 2012 Jun;50(6):2056-61. doi: 10.1016/j.fct.2012.03.055. Epub 2012 Mar 22.

PMID:
22465835
38.

ATP mediates neuroprotective and neuroproliferative effects in mouse olfactory epithelium following exposure to satratoxin G in vitro and in vivo.

Jia C, Sangsiri S, Belock B, Iqbal TR, Pestka JJ, Hegg CC.

Toxicol Sci. 2011 Nov;124(1):169-78. doi: 10.1093/toxsci/kfr213. Epub 2011 Aug 24.

39.

Characterization of deoxynivalenol-induced anorexia using mouse bioassay.

Flannery BM, Wu W, Pestka JJ.

Food Chem Toxicol. 2011 Aug;49(8):1863-9. doi: 10.1016/j.fct.2011.05.004. Epub 2011 May 7.

40.

Body composition and hormonal effects following exposure to mycotoxin deoxynivalenol in the high-fat diet-induced obese mouse.

Kobayashi-Hattori K, Amuzie CJ, Flannery BM, Pestka JJ.

Mol Nutr Food Res. 2011 Jul;55(7):1070-8. doi: 10.1002/mnfr.201000640. Epub 2011 May 2.

41.

Effects of deoxynivalenol consumption on body weight and adiposity in the diet-induced obese mouse.

Amuzie CJ, Flannery BM, Ulrich AM, Pestka JJ.

J Toxicol Environ Health A. 2011;74(10):658-67. doi: 10.1080/15287394.2011.539119.

PMID:
21432715
42.

Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance.

Pestka JJ.

Arch Toxicol. 2010 Sep;84(9):663-79. doi: 10.1007/s00204-010-0579-8. Epub 2010 Aug 27. Review.

PMID:
20798930
43.

Deoxynivalenol-induced proinflammatory gene expression: mechanisms and pathological sequelae.

Pestka JJ.

Toxins (Basel). 2010 Jun;2(6):1300-17. doi: 10.3390/toxins2061300. Epub 2010 Jun 1. Review.

44.

Kinetics of satratoxin g tissue distribution and excretion following intranasal exposure in the mouse.

Amuzie CJ, Islam Z, Kim JK, Seo JH, Pestka JJ.

Toxicol Sci. 2010 Aug;116(2):433-40. doi: 10.1093/toxsci/kfq142. Epub 2010 May 13.

45.
46.

Pulmonary responses to Stachybotrys chartarum and its toxins: mouse strain affects clearance and macrophage cytotoxicity.

Lichtenstein JH, Molina RM, Donaghey TC, Amuzie CJ, Pestka JJ, Coull BA, Brain JD.

Toxicol Sci. 2010 Jul;116(1):113-21. doi: 10.1093/toxsci/kfq104. Epub 2010 Apr 12.

47.

n-3 polyunsaturated fatty acids and autoimmune-mediated glomerulonephritis.

Pestka JJ.

Prostaglandins Leukot Essent Fatty Acids. 2010 Apr-Jun;82(4-6):251-8. doi: 10.1016/j.plefa.2010.02.013. Epub 2010 Mar 1. Review.

48.

Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.

Bae H, Gray JS, Li M, Vines L, Kim J, Pestka JJ.

Toxicol Sci. 2010 Jun;115(2):444-52. doi: 10.1093/toxsci/kfq055. Epub 2010 Feb 24.

49.

DNA damage and DNA damage responses in THP-1 monocytes after exposure to spores of either Stachybotrys chartarum or Aspergillus versicolor or to T-2 toxin.

Rakkestad KE, Skaar I, Ansteinsson VE, Solhaug A, Holme JA, Pestka JJ, Samuelsen JT, Dahlman HJ, Hongslo JK, Becher R.

Toxicol Sci. 2010 May;115(1):140-55. doi: 10.1093/toxsci/kfq045. Epub 2010 Feb 11.

50.

Purification and comparative neurotoxicity of the trichothecenes satratoxin G and roridin L2 from Stachybotrys chartarum.

Islam Z, Shinozuka J, Harkema JR, Pestka JJ.

J Toxicol Environ Health A. 2009;72(20):1242-51. doi: 10.1080/15287390903129234.

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