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Year Number of Results
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1999 1
2000 3
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2002 1
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2005 4
2006 6
2007 7
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125 results

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Page 1
PES1 reduces CD8(+) T cell infiltration and immunotherapy sensitivity via interrupting ILF3-IL15 complex in esophageal squamous cell carcinoma.
Ma N, Hua R, Yang Y, Liu ZC, Pan J, Yu BY, Sun YF, Xie D, Wang Y, Li ZG. Ma N, et al. J Biomed Sci. 2023 Mar 23;30(1):20. doi: 10.1186/s12929-023-00912-8. J Biomed Sci. 2023. PMID: 36959575 Free PMC article.
RESULTS: PES1 was significantly upregulated and correlated with poor prognosis in ESCC patients. ...Analyses on RNA sequencing and mass spectrometry suggested that PES1 expression was negatively correlated with IL15 and ILF3 was one of the PES1-associated pro …
RESULTS: PES1 was significantly upregulated and correlated with poor prognosis in ESCC patients. ...Analyses on RNA sequencing and ma …
PES1 is a biomarker of head and neck squamous cell carcinoma and is associated with the tumor microenvironment.
He Y, Xiang J, Li Y, Huang W, Gu F, Wang Y, Chen R. He Y, et al. Cancer Med. 2023 Jun;12(11):12622-12638. doi: 10.1002/cam4.5948. Epub 2023 Apr 19. Cancer Med. 2023. PMID: 37076985 Free PMC article.
However, in head and neck squamous cell carcinoma (HNSCC), the role of PES1 on the prognosis and immune infiltration remains unknown. METHODS: Multiple databases and qRT-PCR evaluated the expression of PES1 in HNSCC. ...CONCLUSION: We have demonstrated that PES1 …
However, in head and neck squamous cell carcinoma (HNSCC), the role of PES1 on the prognosis and immune infiltration remains unknown. …
PES1 In Liver Cancer: A Prognostic Biomarker With Tumorigenic Roles.
Fu Z, Jiao Y, Li YQ, Ke JJ, Xu YH, Jia BX, Liu B. Fu Z, et al. Cancer Manag Res. 2019 Nov 14;11:9641-9653. doi: 10.2147/CMAR.S226471. eCollection 2019. Cancer Manag Res. 2019. PMID: 31814761 Free PMC article.
Based on bio-informatic analysis, cell experiments and animal models, the aim of this study is to investigate the expression patterns and specific roles of PES1 in liver cancer. PATIENTS AND METHODS: PES1 expression was represented by boxplots. ...GSEA further illum …
Based on bio-informatic analysis, cell experiments and animal models, the aim of this study is to investigate the expression patterns and sp …
PES1 enhances proliferation and tumorigenesis in hepatocellular carcinoma via the PI3K/AKT pathway.
Wang J, Sun J, Zhang N, Yang R, Li H, Zhang Y, Chen K, Kong D. Wang J, et al. Life Sci. 2019 Feb 15;219:182-189. doi: 10.1016/j.lfs.2018.12.054. Epub 2019 Jan 8. Life Sci. 2019. PMID: 30630006
Finally, we found that PES1 affected cell proliferation by regulating the PI3K/AKT/GSK3beta/cyclinD1 signaling pathway. ...Furthermore, PES1 knockdown inhibited the proliferation and tumorigenesis in hepatocellular carcinoma cell lines. ...
Finally, we found that PES1 affected cell proliferation by regulating the PI3K/AKT/GSK3beta/cyclinD1 signaling pathway. ...Furthermor …
PES1 is regulated by CD44 in liver cancer stem cells via miR-105-5p.
Wei S, Liu K, He Q, Gao Y, Shen L. Wei S, et al. FEBS Lett. 2019 Jul;593(14):1777-1786. doi: 10.1002/1873-3468.13459. Epub 2019 Jun 17. FEBS Lett. 2019. PMID: 31127852 Free article.
Pescadillo (PES1) is a key molecule for ribosome formation in mammalian cells. ...In summary, CD44 regulates PES1 in liver cancer stem cells via miR-105-5p to promote cell growth....
Pescadillo (PES1) is a key molecule for ribosome formation in mammalian cells. ...In summary, CD44 regulates PES1 in liver can …
PES1 is a critical component of telomerase assembly and regulates cellular senescence.
Cheng L, Yuan B, Ying S, Niu C, Mai H, Guan X, Yang X, Teng Y, Lin J, Huang J, Jin R, Wu J, Liu B, Chang S, Wang E, Zhang C, Hou N, Cheng X, Xu D, Yang X, Gao S, Ye Q. Cheng L, et al. Sci Adv. 2019 May 15;5(5):eaav1090. doi: 10.1126/sciadv.aav1090. eCollection 2019 May. Sci Adv. 2019. PMID: 31106266 Free PMC article.
PES1 does not interact with the previously reported telomerase components Reptin, Pontin, p23, and Hsp90. ...Thus, we identify a previously unknown telomerase complex, and targeting PES1 may open a new avenue for cancer therapy....
PES1 does not interact with the previously reported telomerase components Reptin, Pontin, p23, and Hsp90. ...Thus, we identify a prev …
PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.
Xie W, Qu L, Meng L, Liu C, Wu J, Shou C. Xie W, et al. Biochem Biophys Res Commun. 2013 Feb 15;431(3):460-5. doi: 10.1016/j.bbrc.2012.12.145. Epub 2013 Jan 16. Biochem Biophys Res Commun. 2013. PMID: 23333390
Up-regulation of PES1 has been documented in some human cancers, indicating that PES1 may play some crucial roles in tumorigenesis. ...Next, results of comet assay revealed decreased DNA repair after PES1-ablation. PES1-ablated cells were more sensitiv …
Up-regulation of PES1 has been documented in some human cancers, indicating that PES1 may play some crucial roles in tumorigen …
PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer.
Jin X, Fang R, Fan P, Zeng L, Zhang B, Lu X, Liu T. Jin X, et al. J Exp Clin Cancer Res. 2019 Nov 12;38(1):463. doi: 10.1186/s13046-019-1466-7. J Exp Clin Cancer Res. 2019. PMID: 31718704 Free PMC article.
BACKGROUND: Overexpressed PES1 promotes carcinogenesis in various types of malignant tumors. ...Targeting PES1 with CDK5 inhibitors might help overcome cancer cell resistance to BET inhibitors in pancreatic cancer cells....
BACKGROUND: Overexpressed PES1 promotes carcinogenesis in various types of malignant tumors. ...Targeting PES1 with CDK5 inhib …
PES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERalpha/ERbeta protein ratio.
Qiu YB, Liao LY, Jiang R, Xu M, Xu LW, Chen GG, Liu ZM. Qiu YB, et al. Sci Rep. 2019 Jan 31;9(1):1032. doi: 10.1038/s41598-018-37648-7. Sci Rep. 2019. PMID: 30705367 Free PMC article.
In PTC tissues, PES1 protein level was positively correlated with the ERalpha protein level and negatively correlated with the ERbeta protein level. The PES1 and ERalpha protein levels were gradually increased and the ERbeta protein level was decreased by degree in …
In PTC tissues, PES1 protein level was positively correlated with the ERalpha protein level and negatively correlated with the ERbeta …
PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma.
Fan P, Wang B, Meng Z, Zhao J, Jin X. Fan P, et al. Int J Biochem Cell Biol. 2018 Nov;104:1-8. doi: 10.1016/j.biocel.2018.08.014. Epub 2018 Aug 29. Int J Biochem Cell Biol. 2018. PMID: 30172011
Here, we reported that PES1 was upregulated and associated with a poor prognosis in HCC specimens. ...Taken together, our results suggest that PES1 plays an important role in promoting the proliferation of human liver cancer cells, suggesting that PES1 may be …
Here, we reported that PES1 was upregulated and associated with a poor prognosis in HCC specimens. ...Taken together, our results sug …
125 results