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Items: 1 to 50 of 485

1.

Antiepileptic drugs: evolution of our knowledge and changes in drug trials.

Perucca E.

Epileptic Disord. 2019 Aug 1;21(4):319-329. doi: 10.1684/epd.2019.1083.

PMID:
31403463
2.

Declining malformation rates with changed antiepileptic drug prescribing: An observational study.

Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Sabers A, Thomas SV, Vajda F; EURAP Study Group.

Neurology. 2019 Aug 27;93(9):e831-e840. doi: 10.1212/WNL.0000000000008001. Epub 2019 Aug 7.

PMID:
31391249
3.

Pharmacological and Therapeutic Properties of Cannabidiol for Epilepsy.

Franco V, Perucca E.

Drugs. 2019 Sep;79(13):1435-1454. doi: 10.1007/s40265-019-01171-4. Review.

PMID:
31372958
4.

Determination of Perampanel in Dried Plasma Spots: Applicability to Therapeutic Drug Monitoring.

Franco V, Baruffi K, Francesca Crema RM, Fattore C, Romigi A, Valentina G, Tartara E, Maurizio E, D'Avolio A, Perucca E.

Ther Drug Monit. 2019 Jul 29. doi: 10.1097/FTD.0000000000000680. [Epub ahead of print]

PMID:
31365481
5.

Classification as autonomic versus sensory seizures.

Fisher RS, Cross H, D'Souza C, French JA, Haut S, Higurashi N, Hirsch E, Jansen FE, Peltola J, Moshe SL, Perucca E, Lagae L, Roulet-Perez E, Schulze-Bonhage A, Scheffer IE, Somerville E, Sperling MR, Wiebe S, Yacubian EM, Zuberi S.

Epilepsia. 2019 Sep;60(9):2003-2005. doi: 10.1111/epi.16308. Epub 2019 Jul 29. No abstract available.

PMID:
31353460
6.

Novel therapies for epilepsy in the pipeline.

Mesraoua B, Deleu D, Kullmann DM, Shetty AK, Boon P, Perucca E, Mikati MA, Asadi-Pooya AA.

Epilepsy Behav. 2019 Aug;97:282-290. doi: 10.1016/j.yebeh.2019.04.042. Epub 2019 Jul 6. Review.

PMID:
31284159
7.

Neurovascular Drug Biotransformation Machinery in Focal Human Epilepsies: Brain CYP3A4 Correlates with Seizure Frequency and Antiepileptic Drug Therapy.

Williams S, Hossain M, Ferguson L, Busch RM, Marchi N, Gonzalez-Martinez J, Perucca E, Najm IM, Ghosh C.

Mol Neurobiol. 2019 Dec;56(12):8392-8407. doi: 10.1007/s12035-019-01673-y. Epub 2019 Jun 26.

PMID:
31243719
8.

The ILAE at 110-Reflections on the last decade.

Wiebe S, Perucca E, Moshe S.

Epilepsia Open. 2019 May 25;4(2):247-253. doi: 10.1002/epi4.12340. eCollection 2019 Jun. No abstract available.

9.

2017 International League Against Epilepsy classifications of seizures and epilepsy are steps in the right direction.

Fisher RS, Cross H, D'Souza C, French JA, Haut S, Higurashi N, Hirsch E, Jansen FE, Peltola J, Moshé SL, Perucca E, Lagae L, Roulet-Perez E, Schulze-Bonhage A, Scheffer IE, Somerville E, Sperling MR, Wiebe S, Yacubian EM, Zuberi S.

Epilepsia. 2019 Jun;60(6):1040-1044. doi: 10.1111/epi.15052. Epub 2019 May 10. No abstract available.

PMID:
31074833
10.

Low risk pragmatic trials do not always require participants' informed consent.

Dal-Ré R, Avendaño-Solà C, Bloechl-Daum B, de Boer A, Eriksson S, Fuhr U, Holm S, James SK, Mentz RJ, Perucca E, Rosendaal FR, Treweek S.

BMJ. 2019 Mar 27;364:l1092. doi: 10.1136/bmj.l1092. No abstract available. Erratum in: BMJ. 2019 Apr 1;365:l1518.

PMID:
30917969
11.

A summary of data presented at the XIV conference on new antiepileptic drug and devices (EILAT XIV).

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsy Res. 2019 Jul;153:66-67. doi: 10.1016/j.eplepsyres.2019.03.002. Epub 2019 Mar 11.

PMID:
30910314
12.

Seizure-alerting behavior in dogs owned by people experiencing seizures.

Martos Martinez-Caja A, De Herdt V, Boon P, Brandl U, Cock H, Parra J, Perucca E, Thadani V, Moons CPH.

Epilepsy Behav. 2019 May;94:104-111. doi: 10.1016/j.yebeh.2019.02.001. Epub 2019 Mar 18.

PMID:
30897533
13.

Identifying mutations in epilepsy genes: Impact on treatment selection.

Perucca P, Perucca E.

Epilepsy Res. 2019 May;152:18-30. doi: 10.1016/j.eplepsyres.2019.03.001. Epub 2019 Mar 4. Review.

PMID:
30870728
14.

Validated outcome of treatment changes according to International League Against Epilepsy criteria in adults with drug-resistant focal epilepsy.

Mula M, Zaccara G, Galimberti CA, Ferrò B, Canevini MP, Mascia A, Mecarelli O, Michelucci R, Pisani LR, Specchio LM, Striano S, Perucca E.

Epilepsia. 2019 Jun;60(6):1114-1123. doi: 10.1111/epi.14685. Epub 2019 Mar 13.

15.

Teratogenicity of antiepileptic drugs.

Tomson T, Battino D, Perucca E.

Curr Opin Neurol. 2019 Apr;32(2):246-252. doi: 10.1097/WCO.0000000000000659.

PMID:
30664067
16.

Perinatal outcome and healthcare resource utilization in the first year of life after antiepileptic exposure during pregnancy.

Putignano D, Clavenna A, Campi R, Canevini MP, Vignoli A, Battino D, Beghi E, Perucca E, Bortolotti A, Fortino I, Merlino L, Bonati M.

Epilepsy Behav. 2019 Mar;92:14-17. doi: 10.1016/j.yebeh.2018.09.033. Epub 2018 Dec 29.

PMID:
30599457
17.

Do neurologists agree in diagnosing drug resistance in adults with focal epilepsy?

Zaccara G, Mula M, Ferrò B, Consoli D, Elia M, Giallonardo AT, Iudice A, La Neve A, Meletti S, Tinuper P, Zummo L, Perucca E.

Epilepsia. 2019 Jan;60(1):175-183. doi: 10.1111/epi.14622. Epub 2018 Dec 25.

PMID:
30585315
18.

From clinical trials of antiepileptic drugs to treatment.

Perucca E.

Epilepsia Open. 2018 Jul 10;3(Suppl Suppl 2):220-230. doi: 10.1002/epi4.12239. eCollection 2018 Dec.

19.

Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development.

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2018 Oct;59(10):1811-1841. doi: 10.1111/epi.14557.

20.

Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). II. Drugs in more advanced clinical development.

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2018 Oct;59(10):1842-1866. doi: 10.1111/epi.14555. Erratum in: Epilepsia. 2019 Jan;60(1):187.

21.

Drug interactions with carbamazepine: An ever expanding list?

Perucca E.

Epilepsy Res. 2018 Nov;147:119-120. doi: 10.1016/j.eplepsyres.2018.08.001. Epub 2018 Aug 6.

PMID:
30220619
22.

EURAP registry: inadequate monitoring of prescribed drugs in pregnancy - Authors' reply.

Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Sabers A, Thomas SV, Vajda F.

Lancet Neurol. 2018 Sep;17(9):741-742. doi: 10.1016/S1474-4422(18)30281-3. No abstract available.

PMID:
30129470
23.

No Evidence of a Causal Role of Antiepileptic Drug Treatment with Regard to the Development of Dementia.

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt JA.

J Am Geriatr Soc. 2018 Sep;66(9):1850-1852. doi: 10.1111/jgs.15467. Epub 2018 Aug 9. No abstract available.

PMID:
30094813
24.

Advocacy for children with epilepsy: Leveraging the WHA resolution. Advocacy Task Force, Commission of Pediatrics, International League Against Epilepsy.

Wilmshurst JM, Guekht A, Secco M, Helen Cross J, Perucca E; Advocacy Task Force, Commission of Pediatrics, International League Against Epilepsy.

Epilepsia Open. 2018 May 14;3(2):167-174. doi: 10.1002/epi4.12220. eCollection 2018 Jun. Review.

25.

No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk-An analysis of Finnish health register and German health insurance data.

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt JA.

Epilepsia. 2018 Jul;59(7):1303-1306. doi: 10.1111/epi.14432. Epub 2018 May 28. No abstract available.

26.

Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.

Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Sabers A, Thomas SV, Vajda F; EURAP Study Group.

Lancet Neurol. 2018 Jun;17(6):530-538. doi: 10.1016/S1474-4422(18)30107-8. Epub 2018 Apr 18.

PMID:
29680205
27.

Final safety, tolerability, and seizure outcomes in patients with focal epilepsy treated with adjunctive perampanel for up to 4 years in an open-label extension of phase III randomized trials: Study 307.

Krauss GL, Perucca E, Kwan P, Ben-Menachem E, Wang XF, Shih JJ, Patten A, Yang H, Williams B, Laurenza A.

Epilepsia. 2018 Apr;59(4):866-876. doi: 10.1111/epi.14044. Epub 2018 Mar 25.

28.

Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?

Perucca E.

J Epilepsy Res. 2017 Dec 31;7(2):61-76. doi: 10.14581/jer.17012. eCollection 2017 Dec. Review.

29.

Genetic testing to prevent adverse reactions to antiepileptic drugs: Primum non nocere.

Guerrini R, Perucca E.

Neurology. 2018 Jan 23;90(4):155-156. doi: 10.1212/WNL.0000000000004869. Epub 2017 Dec 29. No abstract available.

PMID:
29288230
30.

A simple and rapid HPLC-UV method for the determination of retigabine in human plasma.

Franco V, Baruffi K, Gatti G, Marchiselli R, Fattore C, Canevini MP, Crema F, Perucca E.

Biomed Chromatogr. 2018 May;32(5):e4168. doi: 10.1002/bmc.4168. Epub 2018 Jan 24.

PMID:
29235121
31.

Maternal and fetal outcomes associated with vagus nerve stimulation during pregnancy.

Sabers A, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Thomas SV, Tomson T, Vajda F.

Epilepsy Res. 2017 Nov;137:159-162. doi: 10.1016/j.eplepsyres.2017.05.013.

PMID:
29054513
32.

Midazolam vs diazepam in prolonged seizures in children: A pharmacoeconomic approach.

Beghi E, Capovilla G, Franzoni E, Minicucci F, Romeo A, Verrotti A, Vigevano F, Perucca E.

Acta Neurol Scand. 2018 Jan;137(1):24-28. doi: 10.1111/ane.12814. Epub 2017 Sep 6.

PMID:
28875555
33.

How long for epilepsy remission in the ILAE definition?

Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J Jr, Forsgren L, French JA, Hesdorffer DC, Lee BI, Mathern GW, Moshe SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S.

Epilepsia. 2017 Aug;58(8):1486-1487. doi: 10.1111/epi.13821. No abstract available.

34.

Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies.

Pérez-Palma E, Helbig I, Klein KM, Anttila V, Horn H, Reinthaler EM, Gormley P, Ganna A, Byrnes A, Pernhorst K, Toliat MR, Saarentaus E, Howrigan DP, Hoffman P, Miquel JF, De Ferrari GV, Nürnberg P, Lerche H, Zimprich F, Neubauer BA, Becker AJ, Rosenow F, Perucca E, Zara F, Weber YG, Lal D.

J Med Genet. 2017 Sep;54(9):598-606. doi: 10.1136/jmedgenet-2016-104495. Epub 2017 Jul 29.

35.

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology.

Scheffer IE, Berkovic S, Capovilla G, Connolly MB, French J, Guilhoto L, Hirsch E, Jain S, Mathern GW, Moshé SL, Nordli DR, Perucca E, Tomson T, Wiebe S, Zhang YH, Zuberi SM.

Epilepsia. 2017 Apr;58(4):512-521. doi: 10.1111/epi.13709. Epub 2017 Mar 8.

36.

A new classification is born.

Zuberi SM, Perucca E.

Epilepsia. 2017 Apr;58(4):511. doi: 10.1111/epi.13694. Epub 2017 Mar 8. No abstract available.

37.

Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII).

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ.

Epilepsy Res. 2017 Feb;130:27-36. doi: 10.1016/j.eplepsyres.2017.01.004. Epub 2017 Jan 16.

PMID:
28113141
38.

Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII).

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2017 Feb;58(2):181-221. doi: 10.1111/epi.13634. Epub 2017 Jan 23. Review.

39.

Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy, and comorbid depressive-like behavior.

Citraro R, Leo A, Franco V, Marchiselli R, Perucca E, De Sarro G, Russo E.

Epilepsia. 2017 Feb;58(2):231-238. doi: 10.1111/epi.13629. Epub 2016 Dec 18.

40.

Development and Validation of an HPLC-UV Assay for the Therapeutic Monitoring of the New Antiepileptic Drug Perampanel in Human Plasma.

Franco V, Marchiselli R, Fattore C, Tartara E, De Sarro G, Russo E, Perucca E.

Ther Drug Monit. 2016 Dec;38(6):744-750.

PMID:
27753779
41.

A Tribute to Steve White.

Perucca E.

Neurochem Res. 2017 Jul;42(7):1867-1868. doi: 10.1007/s11064-016-2071-1. Epub 2016 Oct 1. No abstract available.

PMID:
27696118
42.

Not all that glitters is gold: A guide to the critical interpretation of drug trials in epilepsy.

Perucca E, Wiebe S.

Epilepsia Open. 2016 Jul 27;1(1-2):9-21. doi: 10.1002/epi4.3. eCollection 2016 Sep. Review.

43.

Classification of the epilepsies: New concepts for discussion and debate-Special report of the ILAE Classification Task Force of the Commission for Classification and Terminology.

Scheffer IE, French J, Hirsch E, Jain S, Mathern GW, Moshé SL, Perucca E, Tomson T, Wiebe S, Zhang YH, Zuberi SM.

Epilepsia Open. 2016 Jul 21;1(1-2):37-44. doi: 10.1002/epi4.5. eCollection 2016 Sep.

44.

Commentary: Message from the ILAE president.

Perucca E.

Epilepsia Open. 2016 Jul 21;1(1-2):8. doi: 10.1002/epi4.6. eCollection 2016 Sep. No abstract available.

45.

Withdrawal of valproic acid treatment during pregnancy and seizure outcome: Observations from EURAP.

Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, Sabers A, Thomas SV, Vajda F; EURAP Study Group.

Epilepsia. 2016 Aug;57(8):e173-7. doi: 10.1111/epi.13437. Epub 2016 Jun 20.

46.

Reflections on monotherapy trials for epilepsy - Authors' reply.

French JA, Mintzer S, Perucca E, Blum DE, Cramer JA, Messenheimer JA, Baulac M.

Lancet Neurol. 2016 Jun;15(7):657-658. doi: 10.1016/S1474-4422(16)00119-8. Epub 2016 May 9. No abstract available.

PMID:
27302226
47.

An investigation of the influence of patient-related factors and comedications on lamotrigine clearance in patients with epilepsy.

Baldoni AO, Freitas-Lima P, de Santi Ferreira FI, Martinez EZ, Queiroz RH, Sakamoto AC, Alexandre V, Perucca E, Pereira LR.

Clin Exp Pharmacol Physiol. 2016 Jul;43(7):685-9. doi: 10.1111/1440-1681.12584.

PMID:
27120710
48.

The safety of generic substitution in epilepsy.

Perucca E.

Lancet Neurol. 2016 Apr;15(4):344-5. doi: 10.1016/S1474-4422(16)00042-9. Epub 2016 Feb 12. No abstract available.

PMID:
26875742
49.

The remarkable story of valproic acid.

Tomson T, Battino D, Perucca E.

Lancet Neurol. 2016 Feb;15(2):141. doi: 10.1016/S1474-4422(15)00398-1. Epub 2016 Jan 12. No abstract available.

PMID:
28463122
50.

In Memoriam: Hanneke De Boer (1946-2015).

Reynolds ET, Covanis A, Perucca E.

Epilepsia. 2016 Jan;57(1):162-3. doi: 10.1111/epi.13293. No abstract available.

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