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Items: 34

1.

Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo.

Urtz N, Gaertner F, von Bruehl ML, Chandraratne S, Rahimi F, Zhang L, Orban M, Barocke V, Beil J, Schubert I, Lorenz M, Legate KR, Huwiler A, Pfeilschifter JM, Beerli C, Ledieu D, Persohn E, Billich A, Baumruker T, Mederos y Schnitzler M, Massberg S.

Circ Res. 2015 Jul 31;117(4):376-87. doi: 10.1161/CIRCRESAHA.115.306901. Epub 2015 Jun 30.

PMID:
26129975
2.

The direct renin inhibitor aliskiren localizes and persists in rat kidneys.

Feldman DL, Jin L, Xuan H, Persohn E, Zhou W, Schuetz H, Park JK, Muller DN, Luft FC.

Am J Physiol Renal Physiol. 2013 Dec 1;305(11):F1593-602. doi: 10.1152/ajprenal.00655.2012. Epub 2013 Aug 7.

3.

Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism.

Fournier B, Murray B, Gutzwiller S, Marcaletti S, Marcellin D, Bergling S, Brachat S, Persohn E, Pierrel E, Bombard F, Hatakeyama S, Trendelenburg AU, Morvan F, Richardson B, Glass DJ, Lach-Trifilieff E, Feige JN.

Mol Cell Biol. 2012 Jul;32(14):2871-9. doi: 10.1128/MCB.06575-11. Epub 2012 May 14.

4.

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.

Herzig MC, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, Stemmelen C, Troxler TJ, Schmid P, Danner S, Schnell CR, Mueller M, Kinzel B, Grevot A, Bolognani F, Stirn M, Kuhn RR, Kaupmann K, van der Putten PH, Rovelli G, Shimshek DR.

Hum Mol Genet. 2011 Nov 1;20(21):4209-23. doi: 10.1093/hmg/ddr348. Epub 2011 Aug 9.

5.

Preclinical evaluation of potential nilotinib cardiotoxicity.

Wolf A, Couttet P, Dong M, Grenet O, Heron M, Junker U, Ledieu D, Mahl A, Marrer E, Persohn E, Pognan F, Zhou W, Tsao J, Roman D.

Leuk Res. 2011 May;35(5):631-7. doi: 10.1016/j.leukres.2010.11.001. Epub 2010 Dec 3.

PMID:
21129774
6.

Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies.

Wolf A, Couttet P, Dong M, Grenet O, Heron M, Junker U, Laengle U, Ledieu D, Marrer E, Nussher A, Persohn E, Pognan F, Rivière GJ, Roth DR, Trendelenburg C, Tsao J, Roman D.

Leuk Res. 2010 Sep;34(9):1180-8. doi: 10.1016/j.leukres.2010.01.004. Epub 2010 Jan 31.

PMID:
20122731
7.

Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats.

Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL, Mueller DN, Feldt S, Cumin F, Maniara W, Persohn E, Schuetz H, Jan Danser AH, Nguyen G.

Hypertension. 2008 Jul;52(1):130-6. doi: 10.1161/HYPERTENSIONAHA.107.108845. Epub 2008 May 19.

PMID:
18490518
8.

Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis.

Foster CA, Howard LM, Schweitzer A, Persohn E, Hiestand PC, Balatoni B, Reuschel R, Beerli C, Schwartz M, Billich A.

J Pharmacol Exp Ther. 2007 Nov;323(2):469-75. Epub 2007 Aug 6.

PMID:
17682127
9.

Cell proliferation measurement in cecum and colon of rats using scanned images and fully automated image analysis: validation of method.

Persohn E, Seewald W, Bauer J, Schreiber J.

Exp Toxicol Pathol. 2007 Aug;58(6):411-8. Epub 2007 Apr 30.

PMID:
17467963
10.

Penetration of ASM 981 in canine skin: a comparative study.

Gutzwiller ME, Reist M, Persohn E, Peel JE, Roosje PJ.

Eur J Drug Metab Pharmacokinet. 2006 Apr-Jun;31(2):53-8.

PMID:
16898071
11.

Morphological and morphometric analysis of paclitaxel and docetaxel-induced peripheral neuropathy in rats.

Persohn E, Canta A, Schoepfer S, Traebert M, Mueller L, Gilardini A, Galbiati S, Nicolini G, Scuteri A, Lanzani F, Giussani G, Cavaletti G.

Eur J Cancer. 2005 Jul;41(10):1460-6.

PMID:
15913989
12.

Imaging of macrophages in soft-tissue infection in rats: relationship between ultrasmall superparamagnetic iron oxide dose and MR signal characteristics.

Lutz AM, Weishaupt D, Persohn E, Goepfert K, Froehlich J, Sasse B, Gottschalk J, Marincek B, Kaim AH.

Radiology. 2005 Mar;234(3):765-75. Epub 2005 Jan 21.

PMID:
15665219
13.

A comparative immunohistochemical study of spontaneous and chemically induced pheochromocytomas in B6C3F1 mice.

Hill GD, Pace V, Persohn E, Bresser C, Haseman JK, Tischler AS, Nyska A.

Endocr Pathol. 2003 Spring;14(1):81-91.

PMID:
12746566
14.

Removal of anti-Galalpha1,3Gal xenoantibodies with an injectable polymer.

Katopodis AG, Warner RG, Duthaler RO, Streiff MB, Bruelisauer A, Kretz O, Dorobek B, Persohn E, Andres H, Schweitzer A, Thoma G, Kinzy W, Quesniaux VF, Cozzi E, Davies HF, Mañez R, White D.

J Clin Invest. 2002 Dec;110(12):1869-77.

15.

Combination of low-dose valsartan and enalapril improves endothelial dysfunction and coronary reserve in Nomega-nitro-L-arginine methyl ester-treated spontaneously hypertensive rats.

de Gasparo M, Hess P, Clozel M, Persohn E, Roman D, Germann PG, Clozel JP, Webb RL.

J Cardiovasc Pharmacol. 2002 Nov;40(5):789-800.

PMID:
12409988
16.

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

Wood JM, Bold G, Buchdunger E, Cozens R, Ferrari S, Frei J, Hofmann F, Mestan J, Mett H, O'Reilly T, Persohn E, Rösel J, Schnell C, Stover D, Theuer A, Towbin H, Wenger F, Woods-Cook K, Menrad A, Siemeister G, Schirner M, Thierauch KH, Schneider MR, Drevs J, Martiny-Baron G, Totzke F.

Cancer Res. 2000 Apr 15;60(8):2178-89.

17.

Induction of apoptosis by the O-hydroxyethyl-D(Ser)(8)-cyclosporine A derivative SDZ IMM 125 in rat hepatocytes.

Grub S, Persohn E, Trommer WE, Wolf A.

J Pharmacol Exp Ther. 2000 Apr;293(1):24-32.

PMID:
10734149
18.

Mechanisms of cyclosporine A-induced apoptosis in rat hepatocyte primary cultures.

Grub S, Persohn E, Trommer WE, Wolf A.

Toxicol Appl Pharmacol. 2000 Mar 15;163(3):209-20.

PMID:
10702360
19.

Effects of intestinal fatty acid-binding protein overexpression on fatty acid metabolism in Caco-2 cells.

Darimont C, Gradoux N, Persohn E, Cumin F, De Pover A.

J Lipid Res. 2000 Jan;41(1):84-92.

20.

Spontaneous malignant craniopharyngioma in an albino rat.

Pace V, Heider K, Persohn E, Schaetti P.

Vet Pathol. 1997 Mar;34(2):146-9.

PMID:
9066081
21.

Spontaneous osteosarcoma of the meninges in an albino rat.

Pace V, Persohn E, Heider K.

Vet Pathol. 1995 Mar;32(2):204-7.

PMID:
7771066
22.

Automated counting of nuclei in series of conventional liver sections to differentiate hypertrophy and hyperplasia.

Wachsmuth ED, Germer M, Paulus K, Persohn E.

Toxicol Appl Pharmacol. 1993 Aug;121(2):264-74.

PMID:
8346543
23.
24.

Comparative molecular neuroanatomy of cloned GABAA receptor subunits in the rat CNS.

Persohn E, Malherbe P, Richards JG.

J Comp Neurol. 1992 Dec 8;326(2):193-216.

PMID:
1336019
26.
27.

Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.

Malherbe P, Sigel E, Baur R, Persohn E, Richards JG, Mohler H.

J Neurosci. 1990 Jul;10(7):2330-7.

28.

Functional expression and sites of gene transcription of a novel alpha subunit of the GABAA receptor in rat brain.

Malherbe P, Sigel E, Baur R, Persohn E, Richards JG, Möhler H.

FEBS Lett. 1990 Jan 29;260(2):261-5.

29.

GABAA-receptor subunits: functional expression and gene localisation.

Mohler H, Malherbe P, Draguhn A, Sigel E, Sequier JM, Persohn E, Richards JG.

Adv Biochem Psychopharmacol. 1990;46:23-34. Review. No abstract available.

PMID:
1963268
30.

Antibodies to the L1 adhesion molecule inhibit Schwann cell ensheathment of neurons in vitro.

Seilheimer B, Persohn E, Schachner M.

J Cell Biol. 1989 Dec;109(6 Pt 1):3095-103.

31.
32.

Neural cell adhesion molecule expression is regulated by Schwann cell-neuron interactions in culture.

Seilheimer B, Persohn E, Schachner M.

J Cell Biol. 1989 May;108(5):1909-15.

34.

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