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Evaluation of the Xpert HCV Viral Load Finger-Stick Point-of-Care Assay.

Lamoury FMJ, Bajis S, Hajarizadeh B, Marshall AD, Martinello M, Ivanova E, Catlett B, Mowat Y, Marks P, Amin J, Smith J, Ezard N, Cock V, Hayllar J, Persing DH, Kleman M, Cunningham P, Dore GJ, Applegate TL, Grebely J; LiveRLife Study Group.

J Infect Dis. 2018 May 25;217(12):1889-1896. doi: 10.1093/infdis/jiy114.


Clinical Impact and Cost-effectiveness of Xpert MTB/RIF Testing in Hospitalized Patients With Presumptive Pulmonary Tuberculosis in the United States.

Cowan JF, Chandler AS, Kracen E, Park DR, Wallis CK, Liu E, Song C, Persing DH, Fang FC.

Clin Infect Dis. 2017 Feb 15;64(4):482-489. doi: 10.1093/cid/ciw803.


Correction: Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus.

Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH.

PLoS One. 2015 Dec 21;10(12):e0145896. doi: 10.1371/journal.pone.0145896. eCollection 2015. No abstract available.


Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus.

Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH.

PLoS One. 2015 Nov 12;10(11):e0142216. doi: 10.1371/journal.pone.0142216. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145896.


Latent tuberculosis: interferon and beyond?

Persing DH.

J Mol Diagn. 2015 Jan;17(1):2-3. doi: 10.1016/j.jmoldx.2014.08.004. No abstract available.


mRNA biomarker detection in liquid-based cytology: a new approach in the prevention of cervical cancer.

Del Pino M, Svanholm-Barrie C, Torné A, Marimon L, Gaber J, Sagasta A, Persing DH, Ordi J.

Mod Pathol. 2015 Feb;28(2):312-20. doi: 10.1038/modpathol.2014.106. Epub 2014 Sep 5.


Strain types and antimicrobial resistance patterns of Clostridium difficile isolates from the United States, 2011 to 2013.

Tickler IA, Goering RV, Whitmore JD, Lynn AN, Persing DH, Tenover FC; Healthcare Associated Infection Consortium.

Antimicrob Agents Chemother. 2014 Jul;58(7):4214-8. doi: 10.1128/AAC.02775-13. Epub 2014 Apr 21.


Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis.

Ma Y, Vilanova D, Atalar K, Delfour O, Edgeworth J, Ostermann M, Hernandez-Fuentes M, Razafimahatratra S, Michot B, Persing DH, Ziegler I, Törös B, Mölling P, Olcén P, Beale R, Lord GM.

PLoS One. 2013 Oct 16;8(10):e75918. doi: 10.1371/journal.pone.0075918. eCollection 2013.


Detection of colonization by carbapenemase-producing Gram-negative Bacilli in patients by use of the Xpert MDRO assay.

Tenover FC, Canton R, Kop J, Chan R, Ryan J, Weir F, Ruiz-Garbajosa P, LaBombardi V, Persing DH.

J Clin Microbiol. 2013 Nov;51(11):3780-7. doi: 10.1128/JCM.01092-13. Epub 2013 Sep 4.


Alternative processing of the U2 small nuclear RNA produces a 19-22nt fragment with relevance for the detection of non-small cell lung cancer in human serum.

Mazières J, Catherinne C, Delfour O, Gouin S, Rouquette I, Delisle MB, Prévot G, Escamilla R, Didier A, Persing DH, Bates M, Michot B.

PLoS One. 2013;8(3):e60134. doi: 10.1371/journal.pone.0060134. Epub 2013 Mar 20.


Antimicrobial-resistant strains of Clostridium difficile from North America.

Tenover FC, Tickler IA, Persing DH.

Antimicrob Agents Chemother. 2012 Jun;56(6):2929-32. doi: 10.1128/AAC.00220-12. Epub 2012 Mar 12.


Characterization of nasal and blood culture isolates of methicillin-resistant Staphylococcus aureus from patients in United States Hospitals.

Tenover FC, Tickler IA, Goering RV, Kreiswirth BN, Mediavilla JR, Persing DH; MRSA Consortium.

Antimicrob Agents Chemother. 2012 Mar;56(3):1324-30. doi: 10.1128/AAC.05804-11. Epub 2011 Dec 12.


Laboratory diagnosis of Clostridium difficile infection can molecular amplification methods move us out of uncertainty?

Tenover FC, Baron EJ, Peterson LR, Persing DH.

J Mol Diagn. 2011 Nov;13(6):573-82. doi: 10.1016/j.jmoldx.2011.06.001. Epub 2011 Aug 18. Review.


A multisite assessment of the quantitative capabilities of the Xpert MTB/RIF assay.

Blakemore R, Nabeta P, Davidow AL, Vadwai V, Tahirli R, Munsamy V, Nicol M, Jones M, Persing DH, Hillemann D, Ruesch-Gerdes S, Leisegang F, Zamudio C, Rodrigues C, Boehme CC, Perkins MD, Alland D.

Am J Respir Crit Care Med. 2011 Nov 1;184(9):1076-84. doi: 10.1164/rccm.201103-0536OC.


Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitals.

Tenover FC, Tickler I, Armstrong ES, Kubo A, Lopez S, Persing DH, Miller GH.

Int J Antimicrob Agents. 2011 Oct;38(4):352-4. doi: 10.1016/j.ijantimicag.2011.05.016. Epub 2011 Aug 5.


Comparison of strain typing results for Clostridium difficile isolates from North America.

Tenover FC, Akerlund T, Gerding DN, Goering RV, Boström T, Jonsson AM, Wong E, Wortman AT, Persing DH.

J Clin Microbiol. 2011 May;49(5):1831-7. doi: 10.1128/JCM.02446-10. Epub 2011 Mar 9.


Evaluation of a rapid and completely automated real-time reverse transcriptase PCR assay for diagnosis of enteroviral meningitis.

Nolte FS, Rogers BB, Tang YW, Oberste MS, Robinson CC, Kehl KS, Rand KA, Rotbart HA, Romero JR, Nyquist AC, Persing DH.

J Clin Microbiol. 2011 Feb;49(2):528-33. doi: 10.1128/JCM.01570-10. Epub 2010 Dec 15.


Rapid molecular detection of tuberculosis and rifampin resistance.

Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD.

N Engl J Med. 2010 Sep 9;363(11):1005-15. doi: 10.1056/NEJMoa0907847. Epub 2010 Sep 1.


Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.

Tenover FC, Novak-Weekley S, Woods CW, Peterson LR, Davis T, Schreckenberger P, Fang FC, Dascal A, Gerding DN, Nomura JH, Goering RV, Akerlund T, Weissfeld AS, Baron EJ, Wong E, Marlowe EM, Whitmore J, Persing DH.

J Clin Microbiol. 2010 Oct;48(10):3719-24. doi: 10.1128/JCM.00427-10. Epub 2010 Aug 11.


Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology.

Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, Kop J, Owens MR, Rodgers R, Banada P, Safi H, Blakemore R, Lan NT, Jones-López EC, Levi M, Burday M, Ayakaka I, Mugerwa RD, McMillan B, Winn-Deen E, Christel L, Dailey P, Perkins MD, Persing DH, Alland D.

J Clin Microbiol. 2010 Jan;48(1):229-37. doi: 10.1128/JCM.01463-09. Epub 2009 Oct 28.


Prevalence and management of invalid GeneXpert enterovirus results obtained with cerebrospinal fluid samples: a 2-year study.

Sefers SE, Raymer AK, Kilby JT, Persing DH, Tang YW.

J Clin Microbiol. 2009 Sep;47(9):3008-10. doi: 10.1128/JCM.01238-09. Epub 2009 Jul 15.


Democratizing molecular diagnostics: the GeneXpert(®) enterovirus assay.

Patel SR, Weir F, Dailey P, Persing DH.

Expert Opin Med Diagn. 2009 Jan;3(1):91-7. doi: 10.1517/17530050802617307.


GeneXpert enterovirus assay: one-year experience in a routine laboratory setting and evaluation on three proficiency panels.

Seme K, Mocilnik T, Komlos KF, Doplihar A, Persing DH, Poljak M.

J Clin Microbiol. 2008 Apr;46(4):1510-3. doi: 10.1128/JCM.01694-07. Epub 2008 Feb 6.


Detection of alpha-methylacyl-coenzyme-A racemase transcripts in blood and urine samples of prostate cancer patients.

Zehentner BK, Secrist H, Zhang X, Hayes DC, Ostenson R, Goodman G, Xu J, Kiviat M, Kiviat N, Persing DH, Houghton RL.

Mol Diagn Ther. 2006;10(6):397-403.


Babesia microti and Borrelia burgdorferi coinfection associated with increased severity of arthritis.

Moro MH, Zegarra-Moro OL, Persing DH.

J Infect Dis. 2006 Sep 1;194(5):716. No abstract available.


Detection of circulating tumor cells in peripheral blood of breast cancer patients during or after therapy using a multigene real-time RT-PCR assay.

Zehentner BK, Secrist H, Hayes DC, Zhang X, Ostenson RC, Loop S, Goodman G, Houghton RL, Persing DH.

Mol Diagn Ther. 2006;10(1):41-7.


Multigene real-time PCR detection of circulating tumor cells in peripheral blood of lung cancer patients.

Hayes DC, Secrist H, Bangur CS, Wang T, Zhang X, Harlan D, Goodman GE, Houghton RL, Persing DH, Zehentner BK.

Anticancer Res. 2006 Mar-Apr;26(2B):1567-75.


Demonstrable parasitemia among Connecticut blood donors with antibodies to Babesia microti.

Leiby DA, Chung AP, Gill JE, Houghton RL, Persing DH, Badon S, Cable RG.

Transfusion. 2005 Nov;45(11):1804-10.


A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease.

Fort MM, Mozaffarian A, Stöver AG, Correia Jda S, Johnson DA, Crane RT, Ulevitch RJ, Persing DH, Bielefeldt-Ohmann H, Probst P, Jeffery E, Fling SP, Hershberg RM.

J Immunol. 2005 May 15;174(10):6416-23.


Decreased levels of interleukin-12p40 in the serum of patients with Whipple's disease.

Kalt A, Schneider T, Ring S, Hoffmann J, Zeitz M, Stallmach A, Persing DH, Marth T.

Int J Colorectal Dis. 2006 Mar;21(2):114-20. Epub 2005 May 5.


CAMP factor homologues in Propionibacterium acnes: a new protein family differentially expressed by types I and II.

Valanne S, McDowell A, Ramage G, Tunney MM, Einarsson GG, O'Hagan S, Wisdom GB, Fairley D, Bhatia A, Maisonneuve JF, Lodes M, Persing DH, Patrick S.

Microbiology. 2005 May;151(Pt 5):1369-79.


Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge.

Cluff CW, Baldridge JR, Stöver AG, Evans JT, Johnson DA, Lacy MJ, Clawson VG, Yorgensen VM, Johnson CL, Livesay MT, Hershberg RM, Persing DH.

Infect Immun. 2005 May;73(5):3044-52.


Propionibacterium acnes types I and II represent phylogenetically distinct groups.

McDowell A, Valanne S, Ramage G, Tunney MM, Glenn JV, McLorinan GC, Bhatia A, Maisonneuve JF, Lodes M, Persing DH, Patrick S.

J Clin Microbiol. 2005 Jan;43(1):326-34. Erratum in: J Clin Microbiol. 2010 Feb;48(2):681.


Mammaglobin as a novel breast cancer biomarker: multigene reverse transcription-PCR assay and sandwich ELISA.

Zehentner BK, Persing DH, Deme A, Toure P, Hawes SE, Brooks L, Feng Q, Hayes DC, Critichlow CW, Houghton RL, Kiviat NB.

Clin Chem. 2004 Nov;50(11):2069-76. Epub 2004 Sep 16.


Babesia divergens-like infection, Washington State.

Herwaldt BL, de Bruyn G, Pieniazek NJ, Homer M, Lofy KH, Slemenda SB, Fritsche TR, Persing DH, Limaye AP.

Emerg Infect Dis. 2004 Apr;10(4):622-9.


Subclinical reactivation of hepatitis B virus in liver transplant recipients with past exposure.

Abdelmalek MF, Pasha TM, Zein NN, Persing DH, Wiesner RH, Douglas DD.

Liver Transpl. 2003 Dec;9(12):1253-7.


Structure-activity relationship of synthetic toll-like receptor 4 agonists.

Stöver AG, Da Silva Correia J, Evans JT, Cluff CW, Elliott MW, Jeffery EW, Johnson DA, Lacy MJ, Baldridge JR, Probst P, Ulevitch RJ, Persing DH, Hershberg RM.

J Biol Chem. 2004 Feb 6;279(6):4440-9. Epub 2003 Oct 21.


Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529.

Evans JT, Cluff CW, Johnson DA, Lacy MJ, Persing DH, Baldridge JR.

Expert Rev Vaccines. 2003 Apr;2(2):219-29. Review.


Immunostimulatory activity of aminoalkyl glucosaminide 4-phosphates (AGPs): induction of protective innate immune responses by RC-524 and RC-529.

Baldridge JR, Cluff CW, Evans JT, Lacy MJ, Stephens JR, Brookshire VG, Wang R, Ward JR, Yorgensen YM, Persing DH, Johnson DA.

J Endotoxin Res. 2002;8(6):453-8.


TAP1, TAP2, and HLA-DR2 alleles are predictors of cervical cancer risk.

Gostout BS, Poland GA, Calhoun ES, Sohni YR, Giuntoli RL 2nd, McGovern RM, Sloan JA, Cha SS, Persing DH.

Gynecol Oncol. 2003 Mar;88(3):326-32.


L523S, an RNA-binding protein as a potential therapeutic target for lung cancer.

Wang T, Fan L, Watanabe Y, McNeill PD, Moulton GG, Bangur C, Fanger GR, Okada M, Inoue Y, Persing DH, Reed SG.

Br J Cancer. 2003 Mar 24;88(6):887-94.


Serum antibodies to lipophilin B detected in late stage breast cancer patients.

Carter D, Dillon DC, Reynolds LD, Retter MW, Fanger G, Molesh DA, Sleath PR, McNeill PD, Vedvick TS, Reed SG, Persing DH, Houghton RL.

Clin Cancer Res. 2003 Feb;9(2):749-54.


Identification and characterization of putative secreted antigens from Babesia microti.

Homer MJ, Lodes MJ, Reynolds LD, Zhang Y, Douglass JF, McNeill PD, Houghton RL, Persing DH.

J Clin Microbiol. 2003 Feb;41(2):723-9.


Systemic symptoms without erythema migrans as the presenting picture of early Lyme disease.

Steere AC, Dhar A, Hernandez J, Fischer PA, Sikand VK, Schoen RT, Nowakowski J, McHugh G, Persing DH.

Am J Med. 2003 Jan;114(1):58-62. No abstract available.


Detection of mammaglobin in the sera of patients with breast cancer.

Fanger GR, Houghton RL, Retter MW, Hendrickson RC, Babcook J, Dillon DC, Durham MD, Reynolds LD, Johnson JC, Carter D, Fleming TP, Roche PC, Persing DH, Reed SG.

Tumour Biol. 2002 Jul-Aug;23(4):212-21.


Relationship between tick bites and the seroprevalence of Babesia microti and Anaplasma phagocytophila (previously Ehrlichia sp.) in blood donors.

Leiby DA, Chung AP, Cable RG, Trouern-Trend J, McCullough J, Homer MJ, Reynolds LD, Houghton RL, Lodes MJ, Persing DH.

Transfusion. 2002 Dec;42(12):1585-91.


Identification of Babesia microti-specific immunodominant epitopes and development of a peptide EIA for detection of antibodies in serum.

Houghton RL, Homer MJ, Reynolds LD, Sleath PR, Lodes MJ, Berardi V, Leiby DA, Persing DH.

Transfusion. 2002 Nov;42(11):1488-96.


Taking toll: lipid A mimetics as adjuvants and immunomodulators.

Persing DH, Coler RN, Lacy MJ, Johnson DA, Baldridge JR, Hershberg RM, Reed SG.

Trends Microbiol. 2002;10(10 Suppl):S32-7. Review.


Host genetic polymorphism analysis in cervical cancer.

Calhoun ES, McGovern RM, Janney CA, Cerhan JR, Iturria SJ, Smith DI, Gostout BS, Persing DH.

Clin Chem. 2002 Aug;48(8):1218-24.

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