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mRNA Detection in Anal Cytology: A Feasible Approach for Anal Cancer Screening in Men Who Have Sex with Men Living With HIV.

Del Pino M, Martí C, Gaber J, Svanholm-Barrie C, Rodríguez-Carunchio L, Rodriguez-Trujillo A, Carreras N, Fuertes I, Barnadas E, Marimón L, Blanco JL, Persing DH, Torné A, Ordi J.

Diagnostics (Basel). 2019 Nov 2;9(4). pii: E173. doi: 10.3390/diagnostics9040173.


Guidelines Support the Value of Stand-Alone Nucleic Acid Amplification Tests for Clostridioides (Clostridium) difficile Infection.

Tenover FC, Persing DH, Fang F.

J Clin Microbiol. 2019 Sep 24;57(10). pii: e01079-19. doi: 10.1128/JCM.01079-19. Print 2019 Oct. No abstract available.


Automatic identification of individual rpoB gene mutations responsible for rifampin resistance in Mycobacterium tuberculosis using melting temperature signatures generated by the Xpert® MTB/RIF Ultra* assay.

Cao Y, Parmar H, Simmons AM, Kale D, Tong K, Lieu D, Persing D, Kwiatkowski R, Alland D, Chakravorty S.

J Clin Microbiol. 2019 Sep 18. pii: JCM.00907-19. doi: 10.1128/JCM.00907-19. [Epub ahead of print]


Multiplex Detection of Three Select Agents Directly from Blood by Use of the GeneXpert System.

Banada PP, Deshpande S, Banik S, Shah D, Koshy R, Patel B, Kwiatkowski R, Persing D, Alland D.

J Clin Microbiol. 2019 Apr 26;57(5). pii: e00036-19. doi: 10.1128/JCM.00036-19. Print 2019 May.


South African women's perspectives on self-sampling for cervical cancer screening: A mixed-methods study.

Saidu R, Moodley J, Tergas A, Momberg M, Boa R, Wright T, Campbell S, Svanholm-Barrie C, Persing D, Kuhn L, Denny L.

S Afr Med J. 2018 Dec 13;109(1):47-52. doi: 10.7196/SAMJ.2018.v109i1.13278.


Evaluation of the Xpert HCV Viral Load Finger-Stick Point-of-Care Assay.

Lamoury FMJ, Bajis S, Hajarizadeh B, Marshall AD, Martinello M, Ivanova E, Catlett B, Mowat Y, Marks P, Amin J, Smith J, Ezard N, Cock V, Hayllar J, Persing DH, Kleman M, Cunningham P, Dore GJ, Applegate TL, Grebely J; LiveRLife Study Group.

J Infect Dis. 2018 May 25;217(12):1889-1896. doi: 10.1093/infdis/jiy114.


Prospective study of the feasibility of point-of-care testing strategy for carbapenem-resistant organism detection.

Pannala R, Baldwin B, Aluru V, Grys TE, Holmes J, Miller LJ, Harrison ME, Nguyen CC, Tenover FC, Persing D, Faigel DO.

Endosc Int Open. 2018 Jan;6(1):E58-E63. doi: 10.1055/s-0043-122141. Epub 2018 Jan 12.


The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing.

Chakravorty S, Simmons AM, Rowneki M, Parmar H, Cao Y, Ryan J, Banada PP, Deshpande S, Shenai S, Gall A, Glass J, Krieswirth B, Schumacher SG, Nabeta P, Tukvadze N, Rodrigues C, Skrahina A, Tagliani E, Cirillo DM, Davidow A, Denkinger CM, Persing D, Kwiatkowski R, Jones M, Alland D.

MBio. 2017 Aug 29;8(4). pii: e00812-17. doi: 10.1128/mBio.00812-17.


Rapid Detection of Bacillus anthracis Bloodstream Infections by Use of a Novel Assay in the GeneXpert System.

Banada PP, Deshpande S, Russo R, Singleton E, Shah D, Patel B, Burday M, Koshy R, Wang Q, Jones M, Gall A, Lokhov S, Kwiatkowski R, Persing D, Connell N, Alland D.

J Clin Microbiol. 2017 Oct;55(10):2964-2971. doi: 10.1128/JCM.00466-17. Epub 2017 Jul 26.


Evaluation of the Xpert HCV Viral Load point-of-care assay from venepuncture-collected and finger-stick capillary whole-blood samples: a cohort study.

Grebely J, Lamoury FMJ, Hajarizadeh B, Mowat Y, Marshall AD, Bajis S, Marks P, Amin J, Smith J, Edwards M, Gorton C, Ezard N, Persing D, Kleman M, Cunningham P, Catlett B, Dore GJ, Applegate TL; LiveRLife Study Group.

Lancet Gastroenterol Hepatol. 2017 Jul;2(7):514-520. doi: 10.1016/S2468-1253(17)30075-4. Epub 2017 Apr 22.


Clinical Impact and Cost-effectiveness of Xpert MTB/RIF Testing in Hospitalized Patients With Presumptive Pulmonary Tuberculosis in the United States.

Cowan JF, Chandler AS, Kracen E, Park DR, Wallis CK, Liu E, Song C, Persing DH, Fang FC.

Clin Infect Dis. 2017 Feb 15;64(4):482-489. doi: 10.1093/cid/ciw803.


Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.

Chakravorty S, Roh SS, Glass J, Smith LE, Simmons AM, Lund K, Lokhov S, Liu X, Xu P, Zhang G, Via LE, Shen Q, Ruan X, Yuan X, Zhu HZ, Viazovkina E, Shenai S, Rowneki M, Lee JS, Barry CE 3rd, Gao Q, Persing D, Kwiatkawoski R, Jones M, Gall A, Alland D.

J Clin Microbiol. 2016 Dec 28;55(1):183-198. doi: 10.1128/JCM.01771-16. Print 2017 Jan.


Chlamydia trachomatis and Neisseria gonorrhoeae in HIV-infected Pregnant Women and Adverse Infant Outcomes.

Adachi K, Klausner JD, Xu J, Ank B, Bristow CC, Morgado MG, Watts DH, Weir F, Persing D, Mofenson LM, Veloso VG, Pilotto JH, Joao E, Gray G, Theron G, Santos B, Fonseca R, Kreitchmann R, Pinto J, Mussi-Pinhata MM, Ceriotto M, Machado DM, Bryson YJ, Grinsztejn B, Bastos FI, Siberry G, Nielsen-Saines K; NICHD HPTN 040 Study Team.

Pediatr Infect Dis J. 2016 Aug;35(8):894-900. doi: 10.1097/INF.0000000000001199.


Correction: Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus.

Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH.

PLoS One. 2015 Dec 21;10(12):e0145896. doi: 10.1371/journal.pone.0145896. eCollection 2015. No abstract available.


Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus.

Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH.

PLoS One. 2015 Nov 12;10(11):e0142216. doi: 10.1371/journal.pone.0142216. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145896.


Chlamydia and Gonorrhea in HIV-Infected Pregnant Women and Infant HIV Transmission.

Adachi K, Klausner JD, Bristow CC, Xu J, Ank B, Morgado MG, Watts DH, Weir F, Persing D, Mofenson LM, Veloso VG, Pilotto JH, Joao E, Nielsen-Saines K; NICHD HPTN 040 Study Team.

Sex Transm Dis. 2015 Oct;42(10):554-65. doi: 10.1097/OLQ.0000000000000340.


Latent tuberculosis: interferon and beyond?

Persing DH.

J Mol Diagn. 2015 Jan;17(1):2-3. doi: 10.1016/j.jmoldx.2014.08.004. No abstract available.


mRNA biomarker detection in liquid-based cytology: a new approach in the prevention of cervical cancer.

Del Pino M, Svanholm-Barrie C, Torné A, Marimon L, Gaber J, Sagasta A, Persing DH, Ordi J.

Mod Pathol. 2015 Feb;28(2):312-20. doi: 10.1038/modpathol.2014.106. Epub 2014 Sep 5.


Strain types and antimicrobial resistance patterns of Clostridium difficile isolates from the United States, 2011 to 2013.

Tickler IA, Goering RV, Whitmore JD, Lynn AN, Persing DH, Tenover FC; Healthcare Associated Infection Consortium.

Antimicrob Agents Chemother. 2014 Jul;58(7):4214-8. doi: 10.1128/AAC.02775-13. Epub 2014 Apr 21.


Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis.

Ma Y, Vilanova D, Atalar K, Delfour O, Edgeworth J, Ostermann M, Hernandez-Fuentes M, Razafimahatratra S, Michot B, Persing DH, Ziegler I, Törös B, Mölling P, Olcén P, Beale R, Lord GM.

PLoS One. 2013 Oct 16;8(10):e75918. doi: 10.1371/journal.pone.0075918. eCollection 2013.


Detection of colonization by carbapenemase-producing Gram-negative Bacilli in patients by use of the Xpert MDRO assay.

Tenover FC, Canton R, Kop J, Chan R, Ryan J, Weir F, Ruiz-Garbajosa P, LaBombardi V, Persing DH.

J Clin Microbiol. 2013 Nov;51(11):3780-7. doi: 10.1128/JCM.01092-13. Epub 2013 Sep 4.


Alternative processing of the U2 small nuclear RNA produces a 19-22nt fragment with relevance for the detection of non-small cell lung cancer in human serum.

Mazières J, Catherinne C, Delfour O, Gouin S, Rouquette I, Delisle MB, Prévot G, Escamilla R, Didier A, Persing DH, Bates M, Michot B.

PLoS One. 2013;8(3):e60134. doi: 10.1371/journal.pone.0060134. Epub 2013 Mar 20.


Antimicrobial-resistant strains of Clostridium difficile from North America.

Tenover FC, Tickler IA, Persing DH.

Antimicrob Agents Chemother. 2012 Jun;56(6):2929-32. doi: 10.1128/AAC.00220-12. Epub 2012 Mar 12.


Characterization of nasal and blood culture isolates of methicillin-resistant Staphylococcus aureus from patients in United States Hospitals.

Tenover FC, Tickler IA, Goering RV, Kreiswirth BN, Mediavilla JR, Persing DH; MRSA Consortium.

Antimicrob Agents Chemother. 2012 Mar;56(3):1324-30. doi: 10.1128/AAC.05804-11. Epub 2011 Dec 12.


Laboratory diagnosis of Clostridium difficile infection can molecular amplification methods move us out of uncertainty?

Tenover FC, Baron EJ, Peterson LR, Persing DH.

J Mol Diagn. 2011 Nov;13(6):573-82. doi: 10.1016/j.jmoldx.2011.06.001. Epub 2011 Aug 18. Review.


A multisite assessment of the quantitative capabilities of the Xpert MTB/RIF assay.

Blakemore R, Nabeta P, Davidow AL, Vadwai V, Tahirli R, Munsamy V, Nicol M, Jones M, Persing DH, Hillemann D, Ruesch-Gerdes S, Leisegang F, Zamudio C, Rodrigues C, Boehme CC, Perkins MD, Alland D.

Am J Respir Crit Care Med. 2011 Nov 1;184(9):1076-84. doi: 10.1164/rccm.201103-0536OC.


Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitals.

Tenover FC, Tickler I, Armstrong ES, Kubo A, Lopez S, Persing DH, Miller GH.

Int J Antimicrob Agents. 2011 Oct;38(4):352-4. doi: 10.1016/j.ijantimicag.2011.05.016. Epub 2011 Aug 5.


Comparison of strain typing results for Clostridium difficile isolates from North America.

Tenover FC, Akerlund T, Gerding DN, Goering RV, Boström T, Jonsson AM, Wong E, Wortman AT, Persing DH.

J Clin Microbiol. 2011 May;49(5):1831-7. doi: 10.1128/JCM.02446-10. Epub 2011 Mar 9.


Evaluation of a rapid and completely automated real-time reverse transcriptase PCR assay for diagnosis of enteroviral meningitis.

Nolte FS, Rogers BB, Tang YW, Oberste MS, Robinson CC, Kehl KS, Rand KA, Rotbart HA, Romero JR, Nyquist AC, Persing DH.

J Clin Microbiol. 2011 Feb;49(2):528-33. doi: 10.1128/JCM.01570-10. Epub 2010 Dec 15.


Rapid molecular detection of tuberculosis and rifampin resistance.

Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD.

N Engl J Med. 2010 Sep 9;363(11):1005-15. doi: 10.1056/NEJMoa0907847. Epub 2010 Sep 1.


Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.

Tenover FC, Novak-Weekley S, Woods CW, Peterson LR, Davis T, Schreckenberger P, Fang FC, Dascal A, Gerding DN, Nomura JH, Goering RV, Akerlund T, Weissfeld AS, Baron EJ, Wong E, Marlowe EM, Whitmore J, Persing DH.

J Clin Microbiol. 2010 Oct;48(10):3719-24. doi: 10.1128/JCM.00427-10. Epub 2010 Aug 11.


Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology.

Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, Kop J, Owens MR, Rodgers R, Banada P, Safi H, Blakemore R, Lan NT, Jones-López EC, Levi M, Burday M, Ayakaka I, Mugerwa RD, McMillan B, Winn-Deen E, Christel L, Dailey P, Perkins MD, Persing DH, Alland D.

J Clin Microbiol. 2010 Jan;48(1):229-37. doi: 10.1128/JCM.01463-09. Epub 2009 Oct 28.


Prevalence and management of invalid GeneXpert enterovirus results obtained with cerebrospinal fluid samples: a 2-year study.

Sefers SE, Raymer AK, Kilby JT, Persing DH, Tang YW.

J Clin Microbiol. 2009 Sep;47(9):3008-10. doi: 10.1128/JCM.01238-09. Epub 2009 Jul 15.


Implementing a real-time PCR assay for rapid surveillance of MRSA.

Persing D, Baron EJ.

MLO Med Lab Obs. 2009 Feb;41(2):18, 20-1. No abstract available.


Democratizing molecular diagnostics: the GeneXpert(®) enterovirus assay.

Patel SR, Weir F, Dailey P, Persing DH.

Expert Opin Med Diagn. 2009 Jan;3(1):91-7. doi: 10.1517/17530050802617307.


Sputum, the final frontier: PCR from the research bench to the MRSA diagnostic trench.

Persing D.

MLO Med Lab Obs. 2008 Nov;40(11):28, 30-1. No abstract available.


GeneXpert enterovirus assay: one-year experience in a routine laboratory setting and evaluation on three proficiency panels.

Seme K, Mocilnik T, Komlos KF, Doplihar A, Persing DH, Poljak M.

J Clin Microbiol. 2008 Apr;46(4):1510-3. doi: 10.1128/JCM.01694-07. Epub 2008 Feb 6.


Pretreatment with toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys.

Adams Waldorf KM, Persing D, Novy MJ, Sadowsky DW, Gravett MG.

Reprod Sci. 2008 Feb;15(2):121-7. doi: 10.1177/1933719107310992. Epub 2008 Jan 9.


Variable expression of immunoreactive surface proteins of Propionibacterium acnes.

Lodes MJ, Secrist H, Benson DR, Jen S, Shanebeck KD, Guderian J, Maisonneuve JF, Bhatia A, Persing D, Patrick S, Skeiky YA.

Microbiology. 2006 Dec;152(Pt 12):3667-81.


Detection of alpha-methylacyl-coenzyme-A racemase transcripts in blood and urine samples of prostate cancer patients.

Zehentner BK, Secrist H, Zhang X, Hayes DC, Ostenson R, Goodman G, Xu J, Kiviat M, Kiviat N, Persing DH, Houghton RL.

Mol Diagn Ther. 2006;10(6):397-403.


Babesia microti and Borrelia burgdorferi coinfection associated with increased severity of arthritis.

Moro MH, Zegarra-Moro OL, Persing DH.

J Infect Dis. 2006 Sep 1;194(5):716. No abstract available.


Detection of circulating tumor cells in peripheral blood of breast cancer patients during or after therapy using a multigene real-time RT-PCR assay.

Zehentner BK, Secrist H, Hayes DC, Zhang X, Ostenson RC, Loop S, Goodman G, Houghton RL, Persing DH.

Mol Diagn Ther. 2006;10(1):41-7.


Multigene real-time PCR detection of circulating tumor cells in peripheral blood of lung cancer patients.

Hayes DC, Secrist H, Bangur CS, Wang T, Zhang X, Harlan D, Goodman GE, Houghton RL, Persing DH, Zehentner BK.

Anticancer Res. 2006 Mar-Apr;26(2B):1567-75.


Demonstrable parasitemia among Connecticut blood donors with antibodies to Babesia microti.

Leiby DA, Chung AP, Gill JE, Houghton RL, Persing DH, Badon S, Cable RG.

Transfusion. 2005 Nov;45(11):1804-10.


A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease.

Fort MM, Mozaffarian A, Stöver AG, Correia Jda S, Johnson DA, Crane RT, Ulevitch RJ, Persing DH, Bielefeldt-Ohmann H, Probst P, Jeffery E, Fling SP, Hershberg RM.

J Immunol. 2005 May 15;174(10):6416-23.


Decreased levels of interleukin-12p40 in the serum of patients with Whipple's disease.

Kalt A, Schneider T, Ring S, Hoffmann J, Zeitz M, Stallmach A, Persing DH, Marth T.

Int J Colorectal Dis. 2006 Mar;21(2):114-20. Epub 2005 May 5.


CAMP factor homologues in Propionibacterium acnes: a new protein family differentially expressed by types I and II.

Valanne S, McDowell A, Ramage G, Tunney MM, Einarsson GG, O'Hagan S, Wisdom GB, Fairley D, Bhatia A, Maisonneuve JF, Lodes M, Persing DH, Patrick S.

Microbiology. 2005 May;151(Pt 5):1369-79.


Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge.

Cluff CW, Baldridge JR, Stöver AG, Evans JT, Johnson DA, Lacy MJ, Clawson VG, Yorgensen VM, Johnson CL, Livesay MT, Hershberg RM, Persing DH.

Infect Immun. 2005 May;73(5):3044-52.


Propionibacterium acnes types I and II represent phylogenetically distinct groups.

McDowell A, Valanne S, Ramage G, Tunney MM, Glenn JV, McLorinan GC, Bhatia A, Maisonneuve JF, Lodes M, Persing DH, Patrick S.

J Clin Microbiol. 2005 Jan;43(1):326-34. Erratum in: J Clin Microbiol. 2010 Feb;48(2):681.


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