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Intraindividual comparison of 18F-PSMA-1007 with renally excreted PSMA ligands for PSMA-PET imaging in patients with relapsed prostate cancer.

Dietlein F, Kobe C, Hohberg M, Zlatopolskiy BD, Krapf P, Endepols H, Täger P, Hammes J, Heidenreich A, Persigehl T, Neumaier B, Drzezga AE, Dietlein M.

J Nucl Med. 2019 Oct 18. pii: jnumed.119.234898. doi: 10.2967/jnumed.119.234898. [Epub ahead of print]


Structured Reporting in Cross-Sectional Imaging of the Heart: Reporting Templates for CMR Imaging of Cardiomyopathies (Myocarditis, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy and Siderosis).

Bunck AC, Baeßler B, Ritter C, Kröger JR, Persigehl T, Pinto D, Steinmetz M, Niehaus A, Bamberg F, Beer M, Ley S, Tiemann K, Beerbaum P, Maintz D, Lotz J.

Rofo. 2019 Oct 9. doi: 10.1055/a-0998-4116. [Epub ahead of print] English, German.


Value of spectral detector computed tomography for assessment of pancreatic lesions.

El Kayal N, Lennartz S, Ekdawi S, Holz J, Slebocki K, Haneder S, Wybranski C, Mohallel A, Eid M, Grüll H, Persigehl T, Borggrefe J, Maintz D, Heneweer C.

Eur J Radiol. 2019 Sep;118:215-222. doi: 10.1016/j.ejrad.2019.07.016. Epub 2019 Jul 16.


Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells.

Erber J, Steiner JD, Isensee J, Lobbes LA, Toschka A, Beleggia F, Schmitt A, Kaiser RWJ, Siedek F, Persigehl T, Hucho T, Reinhardt HC.

Cancer Res. 2019 Oct 1;79(19):4855-4868. doi: 10.1158/0008-5472.CAN-18-3959. Epub 2019 Aug 12.


Stellenwert der MRT in der Differenzialdiagnose des akuten Abdomens einer Schwangeren – Placenta percreta mit akuter, hämodynamisch relevanter Blutung.

Siedek F, Morgenstern B, Alakus H, Persigehl T.

Rofo. 2019 Jul 30. doi: 10.1055/a-0966-8977. [Epub ahead of print] German. No abstract available.


Diagnostic value of spectral reconstructions in detecting incidental skeletal muscle metastases in CT staging examinations.

Lennartz S, Große Hokamp N, Abdullayev N, Le Blanc M, Iuga AI, Bratke G, Zopfs D, Maintz D, Borggrefe J, Persigehl T.

Cancer Imaging. 2019 Jul 17;19(1):50. doi: 10.1186/s40644-019-0235-3.


Intra-individual consistency of spectral detector CT-enabled iodine quantification of the vascular and renal blood pool.

Lennartz S, Abdullayev N, Zopfs D, Borggrefe J, Neuhaus VF, Persigehl T, Haneder S, Große Hokamp N.

Eur Radiol. 2019 Jun 7. doi: 10.1007/s00330-019-06266-w. [Epub ahead of print]


Abscopal Effects in Radio-Immunotherapy-Response Analysis of Metastatic Cancer Patients With Progressive Disease Under Anti-PD-1 Immune Checkpoint Inhibition.

Trommer M, Yeo SY, Persigehl T, Bunck A, Grüll H, Schlaak M, Theurich S, von Bergwelt M, Morgenthaler J, Herter JM, Celik E, Marnitz S, Baues C.

Front Pharmacol. 2019 May 14;10:511. doi: 10.3389/fphar.2019.00511. eCollection 2019.


Low-keV virtual monoenergetic imaging reconstructions of excretory phase spectral dual-energy CT in patients with urothelial carcinoma: A feasibility study.

Zopfs D, Laukamp KR, Pinto Dos Santos D, Sokolowski M, Große Hokamp N, Maintz D, Borggrefe J, Persigehl T, Lennartz S.

Eur J Radiol. 2019 Jul;116:135-143. doi: 10.1016/j.ejrad.2019.05.003. Epub 2019 May 6.


Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial.

Michels S, Massutí B, Schildhaus HU, Franklin J, Sebastian M, Felip E, Grohé C, Rodriguez-Abreu D, Abdulla DSY, Bischoff H, Brandts C, Carcereny E, Corral J, Dingemans AC, Pereira E, Fassunke J, Fischer RN, Gardizi M, Heukamp L, Insa A, Kron A, Menon R, Persigehl T, Reck M, Riedel R, Rothschild SI, Scheel AH, Scheffler M, Schmalz P, Smit EF, Limburg M, Provencio M, Karachaliou N, Merkelbach-Bruse S, Hellmich M, Nogova L, Büttner R, Rosell R, Wolf J.

J Thorac Oncol. 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020. Epub 2019 Apr 9.


Gadofosveset-enhanced MRI as simple surrogate parameter for real-time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF-NGR.

Höink A, Persigehl T, Kwiecien R, Balthasar M, Mesters R, Berdel W, Heindel W, Bremer C, Schwöppe C.

Oncol Lett. 2019 Jan;17(1):270-280. doi: 10.3892/ol.2018.9638. Epub 2018 Oct 29.


Dual-Energy CT-derived Iodine Maps: Use in Assessing Pleural Carcinomatosis.

Lennartz S, Le Blanc M, Zopfs D, Große Hokamp N, Abdullayev N, Laukamp KR, Haneder S, Borggrefe J, Maintz D, Persigehl T.

Radiology. 2019 Mar;290(3):796-804. doi: 10.1148/radiol.2018181567. Epub 2019 Jan 15.


Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU): Technical Background and Overview of Current Clinical Applications (Part 1).

Siedek F, Yeo SY, Heijman E, Grinstein O, Bratke G, Heneweer C, Puesken M, Persigehl T, Maintz D, Grüll H.

Rofo. 2019 Jun;191(6):522-530. doi: 10.1055/a-0817-5645. Epub 2019 Jan 10.


Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU): Overview of Emerging Applications (Part 2).

Siedek F, Yeo SY, Heijman E, Grinstein O, Bratke G, Heneweer C, Puesken M, Persigehl T, Maintz D, Grüll H.

Rofo. 2019 Jun;191(6):531-539. doi: 10.1055/a-0817-5686. Epub 2019 Jan 10.


Monitoring Treatment Response to Erlotinib in EGFR-mutated Non-small-cell Lung Cancer Brain Metastases Using Serial O-(2-[18F]fluoroethyl)-L-tyrosine PET.

Abdulla DSY, Scheffler M, Brandes V, Ruge M, Kunze S, Merkelbach-Bruse S, Nogova L, Michels S, Fischer R, Riedel R, Büttner R, Persigehl T, Grau S, Galldiks N, Drzezga A, Kobe C, Wolf J.

Clin Lung Cancer. 2019 Mar;20(2):e148-e151. doi: 10.1016/j.cllc.2018.10.011. Epub 2018 Nov 5. No abstract available.


Improved visualization of hypodense liver lesions in virtual monoenergetic images from spectral detector CT: Proof of concept in a 3D-printed phantom and evaluation in 74 patients.

Große Hokamp N, Obmann VC, Kessner R, Laukamp KR, Persigehl T, Haneder S, Ramaiya N.

Eur J Radiol. 2018 Dec;109:114-123. doi: 10.1016/j.ejrad.2018.11.001. Epub 2018 Nov 3.


Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors.

Fassunke J, Müller F, Keul M, Michels S, Dammert MA, Schmitt A, Plenker D, Lategahn J, Heydt C, Brägelmann J, Tumbrink HL, Alber Y, Klein S, Heimsoeth A, Dahmen I, Fischer RN, Scheffler M, Ihle MA, Priesner V, Scheel AH, Wagener S, Kron A, Frank K, Garbert K, Persigehl T, Püsken M, Haneder S, Schaaf B, Rodermann E, Engel-Riedel W, Felip E, Smit EF, Merkelbach-Bruse S, Reinhardt HC, Kast SM, Wolf J, Rauh D, Büttner R, Sos ML.

Nat Commun. 2018 Nov 7;9(1):4655. doi: 10.1038/s41467-018-07078-0.


Virtual Monoenergetic Images for Diagnostic Assessment of Hypodense Lesions Within the Liver: Semiautomatic Estimation of Window Settings Using Linear Models.

Große Hokamp N, Obmann VC, Kessner R, Gilkeson RC, Gupta A, Persigehl T, Haneder S, Ramaiya N.

J Comput Assist Tomogr. 2018 Nov/Dec;42(6):925-931. doi: 10.1097/RCT.0000000000000794.


The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression.

Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B, Reinhardt HC.

Cell Rep. 2018 Oct 23;25(4):1027-1039.e6. doi: 10.1016/j.celrep.2018.09.079.


Precision and reliability of liver iodine quantification from spectral detector CT: evidence from phantom and patient data.

Große Hokamp N, Abdullayev N, Persigehl T, Schlaak M, Wybranski C, Holz JA, Streichert T, Alkadhi H, Maintz D, Haneder S.

Eur Radiol. 2019 Apr;29(4):2098-2106. doi: 10.1007/s00330-018-5744-0. Epub 2018 Oct 15.


Accelerated MRI of the Lumbar Spine Using Compressed Sensing: Quality and Efficiency.

Bratke G, Rau R, Weiss K, Kabbasch C, Sircar K, Morelli JN, Persigehl T, Maintz D, Giese D, Haneder S.

J Magn Reson Imaging. 2019 Jun;49(7):e164-e175. doi: 10.1002/jmri.26526. Epub 2018 Sep 29.


Structured Reporting in Clinical Routine.

Pinto Dos Santos D, Hempel JM, Mildenberger P, Klöckner R, Persigehl T.

Rofo. 2019 Jan;191(1):33-39. doi: 10.1055/a-0636-3851. Epub 2018 Aug 13. English, German.


[Image-guided, minimally invasive surgery and other local therapeutic procedures for primary liver tumors].

Stippel DL, Wahba R, Bruns CJ, Bunck A, Baues C, Persigehl T.

Chirurg. 2018 Nov;89(11):872-879. doi: 10.1007/s00104-018-0688-0. Review. German.


4D flow MRI for the analysis of celiac trunk and mesenteric artery stenoses.

Siedek F, Giese D, Weiss K, Ekdawi S, Brinkmann S, Schroeder W, Bruns C, Chang DH, Persigehl T, Maintz D, Haneder S.

Magn Reson Imaging. 2018 Nov;53:52-62. doi: 10.1016/j.mri.2018.06.021. Epub 2018 Jul 3.


Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.

Dafinger C, Rinschen MM, Borgal L, Ehrenberg C, Basten SG, Franke M, Höhne M, Rauh M, Göbel H, Bloch W, Wunderlich FT, Peters DJM, Tasche D, Mishra T, Habbig S, Dötsch J, Müller RU, Brüning JC, Persigehl T, Giles RH, Benzing T, Schermer B, Liebau MC.

Exp Mol Med. 2018 Jun 28;50(6):75. doi: 10.1038/s12276-018-0108-z.


Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?

Safi AF, Kauke M, Jung H, Timmer M, Borggrefe J, Persigehl T, Nickenig HJ, Zinser M, Maintz D, Kreppel M, Zöller J.

J Craniomaxillofac Surg. 2018 Jun;46(6):1013-1018. doi: 10.1016/j.jcms.2018.04.001. Epub 2018 Apr 10.


Anatomical investigations on intraosseous access in stillborns - Comparison of different devices and techniques.

Fuchs Z, Scaal M, Haverkamp H, Koerber F, Persigehl T, Eifinger F.

Resuscitation. 2018 Jun;127:79-82. doi: 10.1016/j.resuscitation.2018.04.003. Epub 2018 Apr 5.


Clinical Evaluation of Free-Breathing Contrast-Enhanced T1w MRI of the Liver using Pseudo Golden Angle Radial k-Space Sampling.

Hedderich DM, Weiss K, Spiro JE, Giese D, Beck GM, Maintz D, Persigehl T.

Rofo. 2018 Jul;190(7):601-609. doi: 10.1055/s-0044-101263. Epub 2018 Mar 13.


Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.

Herling CD, Abedpour N, Weiss J, Schmitt A, Jachimowicz RD, Merkel O, Cartolano M, Oberbeck S, Mayer P, Berg V, Thomalla D, Kutsch N, Stiefelhagen M, Cramer P, Wendtner CM, Persigehl T, Saleh A, Altmüller J, Nürnberg P, Pallasch C, Achter V, Lang U, Eichhorst B, Castiglione R, Schäfer SC, Büttner R, Kreuzer KA, Reinhardt HC, Hallek M, Frenzel LP, Peifer M.

Nat Commun. 2018 Feb 20;9(1):727. doi: 10.1038/s41467-018-03170-7.


AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.

Welcker D, Jain M, Khurshid S, Jokić M, Höhne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Büttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Höpker K.

Oncogene. 2018 Mar;37(11):1503-1518. doi: 10.1038/s41388-017-0054-6. Epub 2018 Jan 11.


Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients.

Plenker D, Bertrand M, de Langen AJ, Riedel R, Lorenz C, Scheel AH, Müller J, Brägelmann J, Daßler-Plenker J, Kobe C, Persigehl T, Kluge A, Wurdinger T, Schellen P, Hartmann G, Zacherle T, Menon R, Thunnissen E, Büttner R, Griesinger F, Wolf J, Heukamp L, Sos ML, Heuckmann JM.

Clin Cancer Res. 2018 Mar 15;24(6):1337-1343. doi: 10.1158/1078-0432.CCR-17-3001. Epub 2017 Dec 28.


Assessment of arterially hyper-enhancing liver lesions using virtual monoenergetic images from spectral detector CT: phantom and patient experience.

Große Hokamp N, Höink AJ, Doerner J, Jordan DW, Pahn G, Persigehl T, Maintz D, Haneder S.

Abdom Radiol (NY). 2018 Aug;43(8):2066-2074. doi: 10.1007/s00261-017-1411-1.


Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer.

Doerr F, George J, Schmitt A, Beleggia F, Rehkämper T, Hermann S, Walter V, Weber JP, Thomas RK, Wittersheim M, Büttner R, Persigehl T, Reinhardt HC.

Sci Rep. 2017 Nov 14;7(1):15511. doi: 10.1038/s41598-017-15840-5.


Assessing renal changes after remote ischemic preconditioning (RIPC) of the upper extremity using BOLD imaging at 3T.

Siedek F, Persigehl T, Mueller RU, Burst V, Benzing T, Maintz D, Haneder S.

MAGMA. 2018 Jun;31(3):367-374. doi: 10.1007/s10334-017-0658-4. Epub 2017 Oct 23.


Investigation of umbilical venous vessels anatomy and diameters as a guideline for catheter placement in newborns.

Eifinger F, Fuchs Z, Koerber F, Persigehl T, Scaal M.

Clin Anat. 2018 Mar;31(2):269-274. doi: 10.1002/ca.22998. Epub 2017 Oct 31.


[Radiological response assessment of modern immunotherapy using iRECIST].

Persigehl T, Poeppel TD, Sedlaczek O.

Radiologe. 2017 Oct;57(10):826-833. doi: 10.1007/s00117-017-0289-9. Review. German.


Magnetic resonance T2 mapping and diffusion-weighted imaging for early detection of cystogenesis and response to therapy in a mouse model of polycystic kidney disease.

Franke M, Baeßler B, Vechtel J, Dafinger C, Höhne M, Borgal L, Göbel H, Koerber F, Maintz D, Benzing T, Schermer B, Persigehl T.

Kidney Int. 2017 Dec;92(6):1544-1554. doi: 10.1016/j.kint.2017.05.024. Epub 2017 Jul 26.


Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia.

Knittel G, Rehkämper T, Korovkina D, Liedgens P, Fritz C, Torgovnick A, Al-Baldawi Y, Al-Maarri M, Cun Y, Fedorchenko O, Riabinska A, Beleggia F, Nguyen PH, Wunderlich FT, Ortmann M, Montesinos-Rongen M, Tausch E, Stilgenbauer S, P Frenzel L, Herling M, Herling C, Bahlo J, Hallek M, Peifer M, Buettner R, Persigehl T, Reinhardt HC.

Nat Commun. 2017 Jul 28;8(1):153. doi: 10.1038/s41467-017-00210-6.


Targeting Fibroblast Growth Factor Receptor 1 for Treatment of Soft-Tissue Sarcoma.

Chudasama P, Renner M, Straub M, Mughal SS, Hutter B, Kosaloglu Z, Schweßinger R, Scheffler M, Alldinger I, Schimmack S, Persigehl T, Kobe C, Jäger D, von Kalle C, Schirmacher P, Beckhaus MK, Wolf S, Heining C, Gröschel S, Wolf J, Brors B, Weichert W, Glimm H, Scholl C, Mechtersheimer G, Specht K, Fröhling S.

Clin Cancer Res. 2017 Feb 15;23(4):962-973. doi: 10.1158/1078-0432.CCR-16-0860. Epub 2016 Aug 17.


Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner.

Jokić M, Vlašić I, Rinneburger M, Klümper N, Spiro J, Vogel W, Offermann A, Kümpers C, Fritz C, Schmitt A, Riabinska A, Wittersheim M, Michels S, Ozretić L, Florin A, Welcker D, Akyuz MD, Nowak M, Erkel M, Wolf J, Büttner R, Schumacher B, Thomale J, Persigehl T, Maintz D, Perner S, Reinhardt HC.

Mol Cancer Res. 2016 Nov;14(11):1110-1123. Epub 2016 Aug 11.


Imaging Procedures for Colorectal Cancer.

Baeßler B, Maintz D, Persigehl T.

Visc Med. 2016 Jun;32(3):166-71. doi: 10.1159/000446143. Epub 2016 Jun 8. Review.


A cohort study on breakthrough invasive fungal infections in high-risk patients receiving antifungal prophylaxis.

Biehl LM, Vehreschild JJ, Liss B, Franke B, Markiefka B, Persigehl T, Bücker V, Wisplinghoff H, Scheid C, Cornely OA, Vehreschild MJ.

J Antimicrob Chemother. 2016 Sep;71(9):2634-41. doi: 10.1093/jac/dkw199. Epub 2016 Jun 17.


Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors.

Ortiz-Cuaran S, Scheffler M, Plenker D, Dahmen L, Scheel AH, Fernandez-Cuesta L, Meder L, Lovly CM, Persigehl T, Merkelbach-Bruse S, Bos M, Michels S, Fischer R, Albus K, König K, Schildhaus HU, Fassunke J, Ihle MA, Pasternack H, Heydt C, Becker C, Altmüller J, Ji H, Müller C, Florin A, Heuckmann JM, Nuernberg P, Ansén S, Heukamp LC, Berg J, Pao W, Peifer M, Buettner R, Wolf J, Thomas RK, Sos ML.

Clin Cancer Res. 2016 Oct 1;22(19):4837-4847. Epub 2016 Jun 1.


B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.

Knittel G, Liedgens P, Korovkina D, Seeger JM, Al-Baldawi Y, Al-Maarri M, Fritz C, Vlantis K, Bezhanova S, Scheel AH, Wolz OO, Reimann M, Möller P, López C, Schlesner M, Lohneis P, Weber AN, Trümper L; German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium, Staudt LM, Ortmann M, Pasparakis M, Siebert R, Schmitt CA, Klatt AR, Wunderlich FT, Schäfer SC, Persigehl T, Montesinos-Rongen M, Odenthal M, Büttner R, Frenzel LP, Kashkar H, Reinhardt HC.

Blood. 2016 Jun 2;127(22):2732-41. doi: 10.1182/blood-2015-11-684183. Epub 2016 Apr 5.


[Modern magnetic resonance imaging of the liver].

Hedderich DM, Weiss K, Maintz D, Persigehl T.

Radiologe. 2015 Dec;55(12):1045-56. doi: 10.1007/s00117-015-0031-4. Review. German.


Implantation of venous access devices under local anesthesia: patients' satisfaction with oral lorazepam.

Chang DH, Hiss S, Herich L, Becker I, Mammadov K, Franke M, Mpotsaris A, Kleinert R, Persigehl T, Maintz D, Bangard C.

Patient Prefer Adherence. 2015 Jul 7;9:943-9. doi: 10.2147/PPA.S80330. eCollection 2015.


A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozretić L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, Siedek F, Persigehl T, Mauch C, Bartkova J, Bradley A, Sprick MR, Trumpp A, Rad R, Saur D, Bartek J, Wolf J, Büttner R, Thomas RK, Reinhardt HC.

Cell. 2015 Jul 2;162(1):146-59. doi: 10.1016/j.cell.2015.05.053. Erratum in: Cell. 2015 Aug 27;162(5):1169.


[Response criteria for malignant melanoma: RECIST and irRC].

Spiro J, Maintz D, Persigehl T.

Radiologe. 2015 Feb;55(2):127-35. doi: 10.1007/s00117-014-2763-y. Review. German.


Assessment of tumor size reduction improves outcome prediction of positron emission tomography/computed tomography after chemotherapy in advanced-stage Hodgkin lymphoma.

Kobe C, Kuhnert G, Kahraman D, Haverkamp H, Eich HT, Franke M, Persigehl T, Klutmann S, Amthauer H, Bockisch A, Kluge R, Wolf HH, Maintz D, Fuchs M, Borchmann P, Diehl V, Drzezga A, Engert A, Dietlein M.

J Clin Oncol. 2014 Jun 10;32(17):1776-81. doi: 10.1200/JCO.2013.53.2507. Epub 2014 May 5.


Variability in assessing treatment response: metastatic colorectal cancer as a paradigm.

Zhao B, Lee SM, Lee HJ, Tan Y, Qi J, Persigehl T, Mozley DP, Schwartz LH.

Clin Cancer Res. 2014 Jul 1;20(13):3560-8. doi: 10.1158/1078-0432.CCR-14-0245. Epub 2014 Apr 29.

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