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Items: 23


The in vitro effects of interferon-gamma, alone or in combination with amphotericin B, tested against the pathogenic fungi Candida albicans and Aspergillus fumigatus.

El-Khoury M, Ligot R, Mahoney S, Stack CM, Perrone GG, Morton CO.

BMC Res Notes. 2017 Aug 1;10(1):364. doi: 10.1186/s13104-017-2696-4.


Unravelling the role of protein kinase CK2 in metal toxicity using gene deletion mutants.

Johnson AJ, Zaman MS, Veljanoski F, Phrakaysone AA, Li S, O'Doherty PJ, Petersingham G, Perrone GG, Molloy MP, Wu MJ.

Metallomics. 2017 Mar 22;9(3):301-308. doi: 10.1039/c6mt00230g.


The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides.

Serhan G, Stack CM, Perrone GG, Morton CO.

Ann Clin Microbiol Antimicrob. 2014 May 12;13:18. doi: 10.1186/1476-0711-13-18.


Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis.

Nair S, Traini M, Dawes IW, Perrone GG.

Mol Biol Cell. 2014 Aug 1;25(15):2235-49. doi: 10.1091/mbc.E13-04-0216. Epub 2014 May 28.


Saccharomyces cerevisiae genes involved in survival of heat shock.

Jarolim S, Ayer A, Pillay B, Gee AC, Phrakaysone A, Perrone GG, Breitenbach M, Dawes IW.

G3 (Bethesda). 2013 Dec 9;3(12):2321-33. doi: 10.1534/g3.113.007971.


Disulfide stress-induced aluminium toxicity: molecular insights through genome-wide screening of Saccharomyces cerevisiae.

Tun NM, O'Doherty PJ, Perrone GG, Bailey TD, Kersaitis C, Wu MJ.

Metallomics. 2013 Aug;5(8):1068-75. doi: 10.1039/c3mt00083d.


Distinct redox regulation in sub-cellular compartments in response to various stress conditions in Saccharomyces cerevisiae.

Ayer A, Sanwald J, Pillay BA, Meyer AJ, Perrone GG, Dawes IW.

PLoS One. 2013 Jun 7;8(6):e65240. doi: 10.1371/journal.pone.0065240. Print 2013.


Oxidative stress and neurodegeneration: the yeast model system.

Breitenbach M, Ralser M, Perrone GG, Iglseder B, Rinnerthaler M, Dawes IW.

Front Biosci (Landmark Ed). 2013 Jun 1;18:1174-93. Review.


A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis.

Ayer A, Fellermeier S, Fife C, Li SS, Smits G, Meyer AJ, Dawes IW, Perrone GG.

PLoS One. 2012;7(9):e44278. doi: 10.1371/journal.pone.0044278. Epub 2012 Sep 6.


The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase.

Park D, Chiu J, Perrone GG, Dilda PJ, Hogg PJ.

Cancer Cell Int. 2012 Mar 26;12(1):11. doi: 10.1186/1475-2867-12-11.


The critical role of glutathione in maintenance of the mitochondrial genome.

Ayer A, Tan SX, Grant CM, Meyer AJ, Dawes IW, Perrone GG.

Free Radic Biol Med. 2010 Dec 15;49(12):1956-68. doi: 10.1016/j.freeradbiomed.2010.09.023. Epub 2010 Sep 29.


Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae.

Greetham D, Vickerstaff J, Shenton D, Perrone GG, Dawes IW, Grant CM.

BMC Biochem. 2010 Jan 14;11:3. doi: 10.1186/1471-2091-11-3.


The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae.

Tan SX, Greetham D, Raeth S, Grant CM, Dawes IW, Perrone GG.

J Biol Chem. 2010 Feb 26;285(9):6118-26. doi: 10.1074/jbc.M109.062844. Epub 2009 Dec 1.


Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae.

Thorsen M, Perrone GG, Kristiansson E, Traini M, Ye T, Dawes IW, Nerman O, Tamás MJ.

BMC Genomics. 2009 Mar 12;10:105. doi: 10.1186/1471-2164-10-105.


Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae.

Tan SX, Teo M, Lam YT, Dawes IW, Perrone GG.

Mol Biol Cell. 2009 Mar;20(5):1493-508. doi: 10.1091/mbc.E08-07-0697. Epub 2009 Jan 7.


Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits.

Herst PM, Perrone GG, Dawes IW, Bircham PW, Berridge MV.

FEMS Yeast Res. 2008 Sep;8(6):897-905. doi: 10.1111/j.1567-1364.2008.00418.x. Epub 2008 Jul 23.


Reactive oxygen species and yeast apoptosis.

Perrone GG, Tan SX, Dawes IW.

Biochim Biophys Acta. 2008 Jul;1783(7):1354-68. doi: 10.1016/j.bbamcr.2008.01.023. Epub 2008 Feb 11. Review.


Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: the role of NADPH-generating systems and the SKN7 transcription factor.

Ng CH, Tan SX, Perrone GG, Thorpe GW, Higgins VJ, Dawes IW.

Free Radic Biol Med. 2008 Mar 15;44(6):1131-45. doi: 10.1016/j.freeradbiomed.2007.12.008. Epub 2007 Dec 23.


Complex cellular responses to reactive oxygen species.

Temple MD, Perrone GG, Dawes IW.

Trends Cell Biol. 2005 Jun;15(6):319-26. Review.


Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae.

Perrone GG, Grant CM, Dawes IW.

Mol Biol Cell. 2005 Jan;16(1):218-30. Epub 2004 Oct 27.


The role of respiration, reactive oxygen species and oxidative stress in mother cell-specific ageing of yeast strains defective in the RAS signalling pathway.

Heeren G, Jarolim S, Laun P, Rinnerthaler M, Stolze K, Perrone GG, Kohlwein SD, Nohl H, Dawes IW, Breitenbach M.

FEMS Yeast Res. 2004 Nov;5(2):157-67.


The selective enzymatic synthesis of lipophilic esters of swainsonine.

Perrone GG, Barrow KD, McFarlane IJ.

Bioorg Med Chem. 1999 May;7(5):831-5.


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