Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 7

1.

Allergen Delivery Inhibitors: A Rationale for Targeting sentinel innate immune signaling of Group 1 house dust mite allergens through structure-based protease inhibitor design.

Zhang J, Chen J, Newton GK, Perrior TR, Robinson C.

Mol Pharmacol. 2018 Jul 5. pii: mol.118.112730. doi: 10.1124/mol.118.112730. [Epub ahead of print]

2.

Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).

Webster SP, McBride A, Binnie M, Sooy K, Seckl JR, Andrew R, Pallin TD, Hunt HJ, Perrior TR, Ruffles VS, Ketelbey JW, Boyd A, Walker BR.

Br J Pharmacol. 2017 Mar;174(5):396-408. doi: 10.1111/bph.13699. Epub 2017 Jan 25.

3.

Discovery to Development: Insecticides for Malaria Vector Control.

Turner JA, Ruscoe CN, Perrior TR.

Chimia (Aarau). 2016 Oct;70(10):684-693. Review.

PMID:
27779925
4.

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma.

Newton GK, Perrior TR, Jenkins K, Major MR, Key RE, Stewart MR, Firth-Clark S, Lloyd SM, Zhang J, Francis-Newton NJ, Richardson JP, Chen J, Lai P, Garrod DR, Robinson C.

J Med Chem. 2014 Nov 26;57(22):9447-62. doi: 10.1021/jm501102h. Epub 2014 Nov 17.

5.

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors.

Donahue EH, Dawson LF, Valiente E, Firth-Clark S, Major MR, Littler E, Perrior TR, Wren BW.

BMC Microbiol. 2014 Aug 31;14:219. doi: 10.1186/s12866-014-0219-1.

6.

Nonhuman targets in allergic lung conditions.

Robinson C, Zhang J, Newton GK, Perrior TR.

Future Med Chem. 2013 Feb;5(2):147-61. doi: 10.4155/fmc.12.204. Review.

PMID:
23360140
7.

Future inhaled drugs by virtual innovation: allergen delivery inhibitors.

Robinson C, Zhang J, Garrod DR, Newton GK, Jenkins K, Perrior TR.

Future Med Chem. 2011 Oct;3(13):1567-70. doi: 10.4155/fmc.11.107. No abstract available.

Supplemental Content

Loading ...
Support Center