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Insights into Praziquantel metabolism and potential enantiomeric CYP-mediated drug-drug interaction.

Vendrell-Navarro G, Scheible H, Lignet F, Burt H, Luepfert C, Marx A, Abla N, Swart P, Perrin D.

Drug Metab Dispos. 2020 Mar 19. pii: dmd.119.089888. doi: 10.1124/dmd.119.089888. [Epub ahead of print]


Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [18F]AmBF3-TATE.

Lau J, Pan J, Rousseau E, Uribe CF, Seelam SR, Sutherland BW, Perrin DM, Lin KS, Bénard F.

EJNMMI Res. 2020 Mar 19;10(1):25. doi: 10.1186/s13550-020-0611-9.


Designing a Rational Follow-Up Schedule for Patients with Extremity Soft Tissue Sarcoma.

Wilson DAJ, Gazendam A, Visgauss J, Perrin D, Griffin AM, Chung PW, Catton CN, Shultz D, Ferguson PC, Wunder JS.

Ann Surg Oncol. 2020 Mar 9. doi: 10.1245/s10434-020-08240-z. [Epub ahead of print]


Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms.

Schaffter T, Buist DSM, Lee CI, Nikulin Y, Ribli D, Guan Y, Lotter W, Jie Z, Du H, Wang S, Feng J, Feng M, Kim HE, Albiol F, Albiol A, Morrell S, Wojna Z, Ahsen ME, Asif U, Jimeno Yepes A, Yohanandan S, Rabinovici-Cohen S, Yi D, Hoff B, Yu T, Chaibub Neto E, Rubin DL, Lindholm P, Margolies LR, McBride RB, Rothstein JH, Sieh W, Ben-Ari R, Harrer S, Trister A, Friend S, Norman T, Sahiner B, Strand F, Guinney J, Stolovitzky G; and the DM DREAM Consortium, Mackey L, Cahoon J, Shen L, Sohn JH, Trivedi H, Shen Y, Buturovic L, Pereira JC, Cardoso JS, Castro E, Kalleberg KT, Pelka O, Nedjar I, Geras KJ, Nensa F, Goan E, Koitka S, Caballero L, Cox DD, Krishnaswamy P, Pandey G, Friedrich CM, Perrin D, Fookes C, Shi B, Cardoso Negrie G, Kawczynski M, Cho K, Khoo CS, Lo JY, Sorensen AG, Jung H.

JAMA Netw Open. 2020 Mar 2;3(3):e200265. doi: 10.1001/jamanetworkopen.2020.0265.


Midterm Success of a Custom, Non-Fluted, Diaphyseal, Press-Fit Stem Used With a Tumor Megaprosthesis System.

Visgauss JD, Perrin DL, Wilson DA, Griffin AM, Wunder JS, Ferguson PC.

J Arthroplasty. 2019 Dec 31. pii: S0883-5403(19)31181-7. doi: 10.1016/j.arth.2019.12.032. [Epub ahead of print]


Improving CRISPR guide design with consensus approaches.

Bradford J, Perrin D.

BMC Genomics. 2019 Dec 24;20(Suppl 9):931. doi: 10.1186/s12864-019-6291-z.


Patient Specific Computer Modelling for Automated Sizing of Fenestrated Stent Grafts.

Derycke L, Sénémaud J, Perrin D, Avril S, Desgranges P, Albertini JN, Cochennec F, Haulon S.

Eur J Vasc Endovasc Surg. 2020 Feb;59(2):237-246. doi: 10.1016/j.ejvs.2019.10.009. Epub 2019 Dec 19.


Toward 18 F-Labeled Theranostics: A Single Agent that Can Be Labeled with 18 F, 64 Cu, or 177 Lu.

Lepage ML, Kuo HT, Roxin Á, Huh S, Zhang Z, Kandasamy R, Merkens H, Kumlin JO, Limoges A, Zeisler SK, Lin KS, Bénard F, Perrin DM.

Chembiochem. 2019 Oct 16. doi: 10.1002/cbic.201900632. [Epub ahead of print]


Synthesis and Activation of Bench-Stable 3a-Fluoropyrroloindolines as Latent Electrophiles for the Synthesis of C-2-Thiol-Substituted Tryptophans and C-3a-Substituted Pyrroloindolines.

Pryyma A, Bu YJ, Wai Y, Patrick BO, Perrin DM.

Org Lett. 2019 Oct 18;21(20):8234-8238. doi: 10.1021/acs.orglett.9b02972. Epub 2019 Oct 9.


18F-Labeled Cyclized α-Melanocyte-Stimulating Hormone Derivatives for Imaging Human Melanoma Xenograft with Positron Emission Tomography.

Zhang C, Zhang Z, Merkens H, Zeisler J, Colpo N, Hundal-Jabal N, Perrin DM, Lin KS, Bénard F.

Sci Rep. 2019 Sep 19;9(1):13575. doi: 10.1038/s41598-019-50014-5.


ACL Size and Notch Width Between ACLR and Healthy Individuals: A Pilot Study.

Wang HM, Shultz SJ, Ross SE, Henson RA, Perrin DH, Schmitz RJ.

Sports Health. 2020 Jan/Feb;12(1):61-65. doi: 10.1177/1941738119873631. Epub 2019 Sep 17.


A benchmark of computational CRISPR-Cas9 guide design methods.

Bradford J, Perrin D.

PLoS Comput Biol. 2019 Aug 29;15(8):e1007274. doi: 10.1371/journal.pcbi.1007274. eCollection 2019 Aug.


MIR spectral characterization of plastic to enable discrimination in an industrial recycling context: II. Specific case of polyolefins.

Signoret C, Caro-Bretelle AS, Lopez-Cuesta JM, Ienny P, Perrin D.

Waste Manag. 2019 Oct;98:160-172. doi: 10.1016/j.wasman.2019.08.010. Epub 2019 Aug 23.


MIR spectral characterization of plastic to enable discrimination in an industrial recycling context: I. Specific case of styrenic polymers.

Signoret C, Caro-Bretelle AS, Lopez-Cuesta JM, Ienny P, Perrin D.

Waste Manag. 2019 Jul 15;95:513-525. doi: 10.1016/j.wasman.2019.05.050. Epub 2019 Jul 1.


Fluorescent Isoindole Crosslink (FlICk) Chemistry: A Rapid, User-friendly Stapling Reaction.

Todorovic M, Schwab KD, Zeisler J, Zhang C, Bénard F, Perrin DM.

Angew Chem Int Ed Engl. 2019 Oct 1;58(40):14120-14124. doi: 10.1002/anie.201906514. Epub 2019 Jul 18.


Sex Comparisons of In Vivo Anterior Cruciate Ligament Morphometry.

Wang HM, Shultz SJ, Ross SE, Henson RA, Perrin DH, Kraft RA, Schmitz RJ.

J Athl Train. 2019 May;54(5):513-518. doi: 10.4085/1062-6050-371-17. Epub 2019 May 6.


A Metal-Free DOTA-Conjugated 18F-Labeled Radiotracer: [18F]DOTA-AMBF3-LLP2A for Imaging VLA-4 Over-Expression in Murine Melanoma with Improved Tumor Uptake and Greatly Enhanced Renal Clearance.

Roxin Á, Zhang C, Huh S, Lepage M, Zhang Z, Lin KS, Bénard F, Perrin DM.

Bioconjug Chem. 2019 Apr 17;30(4):1210-1219. doi: 10.1021/acs.bioconjchem.9b00146. Epub 2019 Apr 8.


Haplotype-resolved and integrated genome analysis of the cancer cell line HepG2.

Zhou B, Ho SS, Greer SU, Spies N, Bell JM, Zhang X, Zhu X, Arthur JG, Byeon S, Pattni R, Saha I, Huang Y, Song G, Perrin D, Wong WH, Ji HP, Abyzov A, Urban AE.

Nucleic Acids Res. 2019 May 7;47(8):3846-3861. doi: 10.1093/nar/gkz169.


Temporal enhancement of 2D color Doppler echocardiography sequences by fragment-based frame reordering and refinement.

Terentjev AB, Perrin DP, Settlemier SH, Zurakowski D, Smirnov PO, Del Nido PJ, Shturts IV, Vasilyev NV.

Int J Comput Assist Radiol Surg. 2019 Apr;14(4):577-586. doi: 10.1007/s11548-019-01926-0. Epub 2019 Feb 23.


One-Step 18F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging.

Kuo HT, Lepage ML, Lin KS, Pan J, Zhang Z, Liu Z, Pryyma A, Zhang C, Merkens H, Roxin A, Perrin DM, Bénard F.

J Nucl Med. 2019 Aug;60(8):1160-1166. doi: 10.2967/jnumed.118.216598. Epub 2019 Feb 8.


Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562.

Zhou B, Ho SS, Greer SU, Zhu X, Bell JM, Arthur JG, Spies N, Zhang X, Byeon S, Pattni R, Ben-Efraim N, Haney MS, Haraksingh RR, Song G, Ji HP, Perrin D, Wong WH, Abyzov A, Urban AE.

Genome Res. 2019 Mar;29(3):472-484. doi: 10.1101/gr.234948.118. Epub 2019 Feb 8.


Predictive Numerical Simulations of Double Branch Stent-Graft Deployment in an Aortic Arch Aneurysm.

Derycke L, Perrin D, Cochennec F, Albertini JN, Avril S.

Ann Biomed Eng. 2019 Apr;47(4):1051-1062. doi: 10.1007/s10439-019-02215-2. Epub 2019 Jan 31.


Rapid analysis of metagenomic data using signature-based clustering.

Chappell T, Geva S, Hogan JM, Huygens F, Rathnayake IU, Rudd S, Kelly W, Perrin D.

BMC Bioinformatics. 2018 Dec 21;19(Suppl 20):509. doi: 10.1186/s12859-018-2540-4.


An intraoperative test device for aortic valve repair.

Berra IG, Hammer PE, Berra S, Irusta AO, Chang Ryu S, Perrin DP, Vasilyev NV, Cornelis CJ, Delucis PG, Del Nido PJ.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):126-132. doi: 10.1016/j.jtcvs.2018.07.113. Epub 2018 Oct 24.


Solid-phase synthesis of a novel phalloidin analog with on-bead and off-bead actin-binding activity.

Blanc A, Todorovic M, Perrin DM.

Chem Commun (Camb). 2019 Jan 2;55(3):385-388. doi: 10.1039/c8cc08379g.


Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy.

Stephansen JB, Olesen AN, Olsen M, Ambati A, Leary EB, Moore HE, Carrillo O, Lin L, Han F, Yan H, Sun YL, Dauvilliers Y, Scholz S, Barateau L, Hogl B, Stefani A, Hong SC, Kim TW, Pizza F, Plazzi G, Vandi S, Antelmi E, Perrin D, Kuna ST, Schweitzer PK, Kushida C, Peppard PE, Sorensen HBD, Jennum P, Mignot E.

Nat Commun. 2018 Dec 6;9(1):5229. doi: 10.1038/s41467-018-07229-3.


How to manage biocomposites wastes end of life? A life cycle assessment approach (LCA) focused on polypropylene (PP)/wood flour and polylactic acid (PLA)/flax fibres biocomposites.

Beigbeder J, Soccalingame L, Perrin D, Bénézet JC, Bergeret A.

Waste Manag. 2019 Jan;83:184-193. doi: 10.1016/j.wasman.2018.11.012. Epub 2018 Nov 15.


Performance of Registration Tools on High-Resolution 3D Brain Images.

Nazib A, Galloway J, Fookes C, Perrin D.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:566-569. doi: 10.1109/EMBC.2018.8512403.


Recursive module extraction using Louvain and PageRank.

Perrin D, Zuccon G.

F1000Res. 2018 Aug 14;7:1286. doi: 10.12688/f1000research.15845.1. eCollection 2018.


Physical fitness of medical residents: Is the health of surgical residents at risk?

Perrin DL, Cordingley DM, Leiter JR, MacDonald PB.

Can J Surg. 2018 Oct 1;61(5):345-349. doi: 10.1503/cjs.012617.


Muscarinic Acetylcholine Receptors Chrm1 and Chrm3 Are Essential for REM Sleep.

Niwa Y, Kanda GN, Yamada RG, Shi S, Sunagawa GA, Ukai-Tadenuma M, Fujishima H, Matsumoto N, Masumoto KH, Nagano M, Kasukawa T, Galloway J, Perrin D, Shigeyoshi Y, Ukai H, Kiyonari H, Sumiyama K, Ueda HR.

Cell Rep. 2018 Aug 28;24(9):2231-2247.e7. doi: 10.1016/j.celrep.2018.07.082.


Physical fitness of medical residents: Is the health of surgical residents at risk?

Perrin DL, Cordingley DM, Leiter JR, MacDonald PB.

Can J Surg. 2018 Aug 1;61(5):12617. doi: 10.1503/cjs.012617. [Epub ahead of print]


Expanding the Balz-Schiemann Reaction: Organotrifluoroborates Serve as Competent Sources of Fluoride Ion for Fluoro-Dediazoniation.

Mohy El Dine T, Sadek O, Gras E, Perrin DM.

Chemistry. 2018 Oct 9;24(56):14933-14937. doi: 10.1002/chem.201803575. Epub 2018 Sep 11.


Promises and Challenges in the Use of Consumer-Grade Devices for Sleep Monitoring.

Roomkham S, Lovell D, Cheung J, Perrin D.

IEEE Rev Biomed Eng. 2018;11:53-67. doi: 10.1109/RBME.2018.2811735. Epub 2018 Mar 8. Review.


Microscale radiosynthesis, preclinical imaging and dosimetry study of [18F]AMBF3-TATE: A potential PET tracer for clinical imaging of somatostatin receptors.

Lisova K, Sergeev M, Evans-Axelsson S, Stuparu AD, Beykan S, Collins J, Jones J, Lassmann M, Herrmann K, Perrin D, Lee JT, Slavik R, van Dam RM.

Nucl Med Biol. 2018 Jun;61:36-44. doi: 10.1016/j.nucmedbio.2018.04.001. Epub 2018 Apr 20.


Melanoma Imaging Using 18F-Labeled α-Melanocyte-Stimulating Hormone Derivatives with Positron Emission Tomography.

Zhang C, Zhang Z, Lin KS, Lau J, Zeisler J, Colpo N, Perrin DM, Bénard F.

Mol Pharm. 2018 Jun 4;15(6):2116-2122. doi: 10.1021/acs.molpharmaceut.7b01113. Epub 2018 May 10.


Organotrifluoroborates as prosthetic groups for Single-Step F18-Labeling of Complex Molecules.

Perrin DM.

Curr Opin Chem Biol. 2018 Aug;45:86-94. doi: 10.1016/j.cbpa.2018.03.001. Epub 2018 Apr 21. Review.


A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover.

Wang Y, Liu E, Lam CH, Perrin DM.

Chem Sci. 2018 Jan 16;9(7):1813-1821. doi: 10.1039/c7sc04491g. eCollection 2018 Feb 21.


Preliminary evaluation of 18F-labeled LLP2A-trifluoroborate conjugates as VLA-4 (α4β1 integrin) specific radiotracers for PET imaging of melanoma.

Roxin Á, Zhang C, Huh S, Lepage ML, Zhang Z, Lin KS, Bénard F, Perrin DM.

Nucl Med Biol. 2018 Jun;61:11-20. doi: 10.1016/j.nucmedbio.2018.02.005. Epub 2018 Mar 12.


Synthesis of the Death-Cap Mushroom Toxin α-Amanitin.

Matinkhoo K, Pryyma A, Todorovic M, Patrick BO, Perrin DM.

J Am Chem Soc. 2018 May 30;140(21):6513-6517. doi: 10.1021/jacs.7b12698. Epub 2018 Mar 21.


High dynamic range ultrasound imaging.

Degirmenci A, Perrin DP, Howe RD.

Int J Comput Assist Radiol Surg. 2018 May;13(5):721-729. doi: 10.1007/s11548-018-1729-3. Epub 2018 Mar 16.


Model reduction methodology for computational simulations of endovascular repair.

Acosta Santamaría VA, Daniel G, Perrin D, Albertini JN, Rosset E, Avril S.

Comput Methods Biomech Biomed Engin. 2018 Feb;21(2):139-148. doi: 10.1080/10255842.2018.1427740. Epub 2018 Jan 30.


Fast image-based mitral valve simulation from individualized geometry.

Villard PF, Hammer PE, Perrin DP, Del Nido PJ, Howe RD.

Int J Med Robot. 2018 Apr;14(2). doi: 10.1002/rcs.1880. Epub 2018 Jan 22.


Recent Advances in 18F Radiochemistry: A Focus on B-18F, Si-18F, Al-18F, and C-18F Radiofluorination via Spirocyclic Iodonium Ylides.

Bernard-Gauthier V, Lepage ML, Waengler B, Bailey JJ, Liang SH, Perrin DM, Vasdev N, Schirrmacher R.

J Nucl Med. 2018 Apr;59(4):568-572. doi: 10.2967/jnumed.117.197095. Epub 2017 Dec 28. Review.


Left Atrial Volumes and Strain in Healthy Children Measured by Three-Dimensional Echocardiography: Normal Values and Maturational Changes.

Ghelani SJ, Brown DW, Kuebler JD, Perrin D, Shakti D, Williams DN, Marx GR, Colan SD, Geva T, Harrild DM.

J Am Soc Echocardiogr. 2018 Feb;31(2):187-193.e1. doi: 10.1016/j.echo.2017.10.011. Epub 2017 Dec 6.


Direct Access to MIDA Acylboronates through Mild Oxidation of MIDA Vinylboronates.

Lepage ML, Lai S, Peressin N, Hadjerci R, Patrick BO, Perrin DM.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15257-15261. doi: 10.1002/anie.201707125. Epub 2017 Oct 25.


Impact of Multileaf Collimator Configuration Parameters on the Dosimetric Accuracy of 6-MV Intensity-Modulated Radiation Therapy Treatment Plans.

Petersen N, Perrin D, Newhauser W, Zhang R.

J Med Phys. 2017 Jul-Sep;42(3):151-155. doi: 10.4103/jmp.JMP_88_16.


Segregating bodily isomerism or heterotaxy: potential echocardiographic correlations of morphological findings.

Tremblay C, Loomba RS, Frommelt PC, Perrin D, Spicer DE, Backer C, Anderson RH.

Cardiol Young. 2017 Oct;27(8):1470-1480. doi: 10.1017/S104795111700049X. Epub 2017 Apr 3.


Analysis of professional competencies for the clinical research data management profession: implications for training and professional certification.

Zozus MN, Lazarov A, Smith LR, Breen TE, Krikorian SL, Zbyszewski PS, Knoll SK, Jendrasek DA, Perrin DC, Zambas DN, Williams TB, Pieper CF.

J Am Med Inform Assoc. 2017 Jul 1;24(4):737-745. doi: 10.1093/jamia/ocw179.


Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome.

Collins RL, Brand H, Redin CE, Hanscom C, Antolik C, Stone MR, Glessner JT, Mason T, Pregno G, Dorrani N, Mandrile G, Giachino D, Perrin D, Walsh C, Cipicchio M, Costello M, Stortchevoi A, An JY, Currall BB, Seabra CM, Ragavendran A, Margolin L, Martinez-Agosto JA, Lucente D, Levy B, Sanders SJ, Wapner RJ, Quintero-Rivera F, Kloosterman W, Talkowski ME.

Genome Biol. 2017 Mar 6;18(1):36. doi: 10.1186/s13059-017-1158-6.

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