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Anti-adenovirus humoral responses influence on the efficacy of vaccines based on epitope display on adenovirus capsid.

Lanzi A, Ben Youssef G, Perricaudet M, Benihoud K.

Vaccine. 2011 Feb 4;29(7):1463-71. doi: 10.1016/j.vaccine.2010.12.025. Epub 2010 Dec 22.


HARPΔ111-136 enhances radiation-induced apoptosis of U87MG glioblastoma by induction of the proapoptotic protein CHOP.

Karaky R, Gobbo E, Opolon P, Delbé J, Courty J, Griscelli F, Perricaudet M, Martel-Renoir D.

Int J Oncol. 2011 Jan;38(1):179-88.


The soluble fragment of VE-cadherin inhibits angiogenesis by reducing endothelial cell proliferation and tube capillary formation.

Li H, Shi X, Liu J, Hu C, Zhang X, Liu H, Jin J, Opolon P, Vannier JP, Perricaudet M, Janin A, Soria C, Lu H.

Cancer Gene Ther. 2010 Oct;17(10):700-7. doi: 10.1038/cgt.2010.26. Epub 2010 Jun 18.


Antitumorigenic effects of a mutant of the heparin affin regulatory peptide on the U87 MG glioblastoma cell line.

Dos Santos C, Karaky R, Renoir D, Hamma-Kourbali Y, Albanese P, Gobbo E, Griscelli F, Opolon P, Dalle S, Perricaudet M, Courty J, Delbé J.

Int J Cancer. 2010 Sep 1;127(5):1038-51. doi: 10.1002/ijc.25110.


Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid.

Jullienne B, Vigant F, Muth E, Chaligné R, Bouquet C, Giraudier S, Perricaudet M, Benihoud K.

Gene Ther. 2009 Dec;16(12):1405-15. doi: 10.1038/gt.2009.97.


16-kDa fragment of pleiotrophin acts on endothelial and breast tumor cells and inhibits tumor development.

Ducès A, Karaky R, Martel-Renoir D, Mir L, Hamma-Kourbali Y, Biéche I, Opolon P, Delbé J, Courty J, Perricaudet M, Griscelli F.

Mol Cancer Ther. 2008 Sep;7(9):2817-27. doi: 10.1158/1535-7163.MCT-08-0301.


Antitumoral activity and osteogenic potential of mesenchymal stem cells expressing the urokinase-type plasminogen antagonist amino-terminal fragment in a murine model of osteolytic tumor.

Fritz V, Noël D, Bouquet C, Opolon P, Voide R, Apparailly F, Louis-Plence P, Bouffi C, Drissi H, Xie C, Perricaudet M, Müller R, Schwarz E, Jorgensen C.

Stem Cells. 2008 Nov;26(11):2981-90. doi: 10.1634/stemcells.2008-0139. Epub 2008 Aug 28.


Reduction of brain metastases in plasminogen activator inhibitor-1-deficient mice with transgenic ocular tumors.

Maillard CM, Bouquet C, Petitjean MM, Mestdagt M, Frau E, Jost M, Masset AM, Opolon PH, Beermann F, Abitbol MM, Foidart JM, Perricaudet MJ, Noël AC.

Carcinogenesis. 2008 Nov;29(11):2236-42. doi: 10.1093/carcin/bgn204. Epub 2008 Aug 27.


Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver.

Vigant F, Descamps D, Jullienne B, Esselin S, Connault E, Opolon P, Tordjmann T, Vigne E, Perricaudet M, Benihoud K.

Mol Ther. 2008 Aug;16(8):1474-80. doi: 10.1038/mt.2008.132. Epub 2008 Jun 17.


Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment.

Magnon C, Opolon P, Connault E, Mir LM, Perricaudet M, Martel-Renoir D.

Gene Ther. 2008 Nov;15(21):1436-45. doi: 10.1038/gt.2008.100. Epub 2008 Jun 12.


High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.

Marot D, Bieche I, Aumas C, Esselin S, Bouquet C, Vacher S, Lazennec G, Perricaudet M, Kuttenn F, Lidereau R, de Roux N.

Endocr Relat Cancer. 2007 Sep;14(3):691-702.


Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1alpha-mediated tumor apoptotic switch.

Magnon C, Opolon P, Ricard M, Connault E, Ardouin P, Galaup A, Métivier D, Bidart JM, Germain S, Perricaudet M, Schlumberger M.

J Clin Invest. 2007 Jul;117(7):1844-55.


Adenoviral-mediated TGF-beta1 inhibition in a mouse model of myelofibrosis inhibit bone marrow fibrosis development.

Gastinne T, Vigant F, Lavenu-Bombled C, Wagner-Ballon O, Tulliez M, Chagraoui H, Villeval JL, Lacout C, Perricaudet M, Vainchenker W, Benihoud K, Giraudier S.

Exp Hematol. 2007 Jan;35(1):64-74.


Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice.

Benihoud K, Esselin S, Descamps D, Jullienne B, Salone B, Bobé P, Bonardelle D, Connault E, Opolon P, Saggio I, Perricaudet M.

Gene Ther. 2007 Mar;14(6):533-44. Epub 2006 Nov 16. Erratum in: Gene Ther. 2007 Mar;14(6):551.


A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer.

Frau E, Magnon C, Opolon P, Connault E, Opolon D, Beermann F, Abitbol M, Perricaudet M, Bouquet C.

Cancer Gene Ther. 2007 Mar;14(3):251-61. Epub 2006 Nov 3. Erratum in: Cancer Gene Ther. 2007 Apr;14(4):440. Beerman, F [corrected to Beermann, F].


Dynamic assessment of antiangiogenic therapy by monitoring both tumoral vascularization and tissue degeneration.

Magnon C, Galaup A, Rouffiac V, Opolon P, Connault E, Rosé M, Perricaudet M, Roche A, Germain S, Griscelli F, Lassau N.

Gene Ther. 2007 Jan;14(2):108-17. Epub 2006 Aug 31. Erratum in: Gene Ther. 2007 Jan;14(2):190.


Expression of non-signaling membrane-anchored death receptors protects murine livers in different models of hepatitis.

Descamps D, Vigant F, Esselin S, Connault E, Opolon P, Perricaudet M, Benihoud K.

Hepatology. 2006 Aug;44(2):399-409.


A soluble truncated cadherin induces breast cancer cell apoptosis and growth inhibition.

Shi XY, Lu H, Li WL, Tang HL, Xiong JJ, Zhang JQ, Opolon P, Legrand C, Perricaudet M, Li H.

J Cancer Res Clin Oncol. 2006 Sep;132(9):561-71. Epub 2006 Jun 9.


Suppression of angiogenesis, tumor growth, and metastasis by adenovirus-mediated gene transfer of human angiotensinogen.

Bouquet C, Lamandé N, Brand M, Gasc JM, Jullienne B, Faure G, Griscelli F, Opolon P, Connault E, Perricaudet M, Corvol P.

Mol Ther. 2006 Aug;14(2):175-82. Epub 2006 Apr 5.


Recombinant interleukin-2 pre-treatment increases anti-tumor response to paclitaxel by affecting lung P-glycoprotein expression on the Lewis lung carcinoma.

Hosten B, Challuau D, Gil S, Bouquet C, Marion S, Perricaudet M, Di Palma M, Farinotti R, Bonhomme-Faivre L.

Anticancer Drugs. 2006 Feb;17(2):195-9.


Amino-terminal fragment of urokinase inhibits tumor cell invasion in vitro and in vivo: respective contribution of the urokinase plasminogen activator receptor-dependent or -independent pathway.

Li H, Soria C, Griscelli F, Opolon P, Soria J, Yeh P, Legrand C, Vannier JP, Belin D, Perricaudet M, Lu H.

Hum Gene Ther. 2005 Oct;16(10):1157-67.


The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers.

Marot D, Opolon P, Brailly-Tabard S, Elie N, Randrianarison V, Connault E, Foray N, Feunteun J, Perricaudet M.

Gene Ther. 2006 Feb;13(3):235-44.


In vitro echogenicity characterization of poly[lactide-coglycolide] (plga) microparticles and preliminary in vivo ultrasound enhancement study for ultrasound contrast agent application.

Lavisse S, Paci A, Rouffiac V, Adotevi C, Opolon P, Peronneau P, Bourget P, Roche A, Perricaudet M, Fattal E, Lassau N.

Invest Radiol. 2005 Aug;40(8):536-44.


Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with alphavbeta3 and alphavbeta5 integrins.

Magnon C, Galaup A, Mullan B, Rouffiac V, Bouquet C, Bidart JM, Griscelli F, Opolon P, Perricaudet M.

Cancer Res. 2005 May 15;65(10):4353-61. Erratum in: Cancer Res. 2005 Jul 1;65(13):5989. Bouquet, Céline [added].


Full kringles of plasminogen (aa 1-566) mediate complete regression of human MDA-MB-231 breast tumor xenografted in nude mice.

Galaup A, Magnon C, Rouffiac V, Opolon P, Opolon D, Lassau N, Tursz T, Perricaudet M, Griscelli F.

Gene Ther. 2005 May;12(10):831-42.


Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats.

Faivre J, Clerc J, Gérolami R, Hervé J, Longuet M, Liu B, Roux J, Moal F, Perricaudet M, Bréchot C.

Cancer Res. 2004 Nov 1;64(21):8045-51. Erratum in: Cancer Res. 2004 Dec 15;64(24):9230.


Robust functional gene validation by adenoviral vectors: one-step Escherichia coli-derived recombinant adenoviral genome construction.

Mullan B, Dugué C, Moutard V, Raoux D, Tremp G, Denèfle P, Perricaudet M, Robert JJ.

Gene Ther. 2004 Nov;11(21):1599-605.


Validation of a new method for quantifying in vivo murine tumor necrosis by sonography.

Rouffiac V, Bouquet C, Lassau N, Opolon P, Koscielny S, Peronneau P, Perricaudet M, Roche A.

Invest Radiol. 2004 Jun;39(6):350-6.


Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin.

Trochon-Joseph V, Martel-Renoir D, Mir LM, Thomaïdis A, Opolon P, Connault E, Li H, Grenet C, Fauvel-Lafève F, Soria J, Legrand C, Soria C, Perricaudet M, Lu H.

Cancer Res. 2004 Mar 15;64(6):2062-9.


Short-term BMP-2 expression is sufficient for in vivo osteochondral differentiation of mesenchymal stem cells.

Noël D, Gazit D, Bouquet C, Apparailly F, Bony C, Plence P, Millet V, Turgeman G, Perricaudet M, Sany J, Jorgensen C.

Stem Cells. 2004;22(1):74-85.


High level of stabilized angiostatin mediated by adenovirus delivery does not impair the growth of human neuroblastoma xenografts.

Joseph JM, Bouquet C, Opolon P, Morizet J, Aubert G, Rössler J, Gross N, Griscelli F, Perricaudet M, Vassal G.

Cancer Gene Ther. 2003 Nov;10(11):859-66.


In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy.

Le Gat L, Gogat K, Bouquet C, Saint-Geniez M, Darland D, Van Den Berghe L, Marchant D, Provost A, Perricaudet M, Menasche M, Abitbol M.

Gene Ther. 2003 Dec;10(25):2098-103.


Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase.

Thévenot E, Côté F, Colin P, He Y, Leblois H, Perricaudet M, Mallet J, Vodjdani G.

Mol Cell Neurosci. 2003 Sep;24(1):139-47.


Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse).

de Pontual L, Népote V, Attié-Bitach T, Al Halabiah H, Trang H, Elghouzzi V, Levacher B, Benihoud K, Augé J, Faure C, Laudier B, Vekemans M, Munnich A, Perricaudet M, Guillemot F, Gaultier C, Lyonnet S, Simonneau M, Amiel J.

Hum Mol Genet. 2003 Dec 1;12(23):3173-80. Epub 2003 Oct 7.


Simultaneous CAR- and alpha V integrin-binding ablation fails to reduce Ad5 liver tropism.

Martin K, Brie A, Saulnier P, Perricaudet M, Yeh P, Vigne E.

Mol Ther. 2003 Sep;8(3):485-94.


Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells.

Dkhissi F, Lu H, Soria C, Opolon P, Griscelli F, Liu H, Khattar P, Mishal Z, Perricaudet M, Li H.

Hum Gene Ther. 2003 Jul 1;14(10):997-1008.


Combined effects of docetaxel and angiostatin gene therapy in prostate tumor model.

Galaup A, Opolon P, Bouquet C, Li H, Opolon D, Bissery MC, Tursz T, Perricaudet M, Griscelli F.

Mol Ther. 2003 Jun;7(6):731-40.


A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.

Foray N, Marot D, Gabriel A, Randrianarison V, Carr AM, Perricaudet M, Ashworth A, Jeggo P.

EMBO J. 2003 Jun 2;22(11):2860-71.


Lung overexpression of angiostatin aggravates pulmonary hypertension in chronically hypoxic mice.

Pascaud MA, Griscelli F, Raoul W, Marcos E, Opolon P, Raffestin B, Perricaudet M, Adnot S, Eddahibi S.

Am J Respir Cell Mol Biol. 2003 Oct;29(4):449-57. Epub 2003 Apr 24.


Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation.

Vigne E, Dedieu JF, Brie A, Gillardeaux A, Briot D, Benihoud K, Latta-Mahieu M, Saulnier P, Perricaudet M, Yeh P.

Gene Ther. 2003 Jan;10(2):153-62.


Adenovirus-mediated gene transfer to the transplanted piglet heart after intracoronary injection.

Griscelli F, Belli E, Opolon P, Musset K, Connault E, Perricaudet M, Serraf A, Mazmanian GM, Ragot T.

J Gene Med. 2003 Feb;5(2):109-19.


Adenovirus-mediated gene transfer in dog prostate: a preclinical study of a relevant model system for gene therapy of human prostatic cancer.

Andrawiss M, Opolon P, Benihoud K, Devauchelle P, Di Falco N, Villette JM, Kremer E, Saulnier P, Berthon P, Perricaudet M, Cussenot O.

Prostate Cancer Prostatic Dis. 1999 Jan;2(1):25-35.


Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.

Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P.

Mol Cell Biol. 2002 Jun;22(12):4020-32.


Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse.

Kalamarides M, Niwa-Kawakita M, Leblois H, Abramowski V, Perricaudet M, Janin A, Thomas G, Gutmann DH, Giovannini M.

Genes Dev. 2002 May 1;16(9):1060-5.


Degenerated pIX-IVa2 adenoviral vector sequences lowers reacquisition of the E1 genes during virus amplification in 293 cells.

Robert JJ, Gauffeny I, Maccario J, Jullien C, Benoit P, Vigne E, Crouzet J, Perricaudet M, Yeh P.

Gene Ther. 2001 Nov;8(22):1713-20.


Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis.

Apparailly F, Bouquet C, Millet V, Noel D, Jacquet C, Opolon P, Perricaudet M, Sany J, Yeh P, Jorgensen C.

Gene Ther. 2002 Feb;9(3):192-200.


Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers.

Boland A, Magnon C, Filetti S, Bidart JM, Schlumberger M, Yeh P, Perricaudet M.

Thyroid. 2002 Jan;12(1):19-26.


BRCA1 carries tumor suppressor activity distinct from that of p53 and p21.

Randrianarison V, Marot D, Foray N, Cabannes J, Méret V, Connault E, Vitrat N, Opolon P, Perricaudet M, Feunteun J.

Cancer Gene Ther. 2001 Oct;8(10):759-70.

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