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Items: 1 to 50 of 92

1.

Assessment of the safety of Bacillus Calmette-Guérin vaccine administered orally to badgers (Meles meles).

Perrett S, Lesellier S, Rogers F, Williams GA, Gowtage S, Palmer S, Dalley D, Davé D, Weyer U, Wood E, Salguero FJ, Nunez A, Reed N, Chambers MA.

Vaccine. 2018 Apr 5;36(15):1990-1995. doi: 10.1016/j.vaccine.2018.02.101. Epub 2018 Mar 7.

PMID:
29525277
2.

Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2.

Yang J, Dear AJ, Michaels TCT, Dobson CM, Knowles TPJ, Wu S, Perrett S.

J Am Chem Soc. 2018 Feb 21;140(7):2493-2503. doi: 10.1021/jacs.7b10439. Epub 2018 Feb 7.

3.

The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation.

Xu L, Gong W, Cusack SA, Wu H, Loovers HM, Zhang H, Perrett S, Jones GW.

Cell Mol Life Sci. 2018 Apr;75(8):1445-1459. doi: 10.1007/s00018-017-2698-3. Epub 2017 Nov 9.

4.

A co-expression strategy to achieve labeling of individual subunits within a dimeric protein for single molecule analysis.

Lou F, Yang J, Wu S, Perrett S.

Chem Commun (Camb). 2017 Jul 13;53(57):7986-7989. doi: 10.1039/c7cc03032k.

PMID:
28650509
5.

Selective Proteomic Proximity Labeling Assay Using Tyramide (SPPLAT): A Quantitative Method for the Proteomic Analysis of Localized Membrane-Bound Protein Clusters.

Rees JS, Li XW, Perrett S, Lilley KS, Jackson AP.

Curr Protoc Protein Sci. 2017 Apr 3;88:19.27.1-19.27.18. doi: 10.1002/cpps.27.

PMID:
28369668
6.

The propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor.

Yang W, Willemse J, Sawyer EB, Lou F, Gong W, Zhang H, Gras SL, Claessen D, Perrett S.

Sci Rep. 2017 Feb 17;7:42867. doi: 10.1038/srep42867.

7.

Glutathionylation of the Bacterial Hsp70 Chaperone DnaK Provides a Link between Oxidative Stress and the Heat Shock Response.

Zhang H, Yang J, Wu S, Gong W, Chen C, Perrett S.

J Biol Chem. 2016 Mar 25;291(13):6967-81. doi: 10.1074/jbc.M115.673608. Epub 2016 Jan 28.

8.

The C-terminal region of human eukaryotic elongation factor 1Bδ.

Wu H, Wang C, Gong W, Wang J, Xuan J, Perrett S, Feng Y.

J Biomol NMR. 2016 Feb;64(2):181-7. doi: 10.1007/s10858-016-0012-6. Epub 2016 Jan 13. No abstract available.

PMID:
26762120
9.

Protein Neighbors and Proximity Proteomics.

Rees JS, Li XW, Perrett S, Lilley KS, Jackson AP.

Mol Cell Proteomics. 2015 Nov;14(11):2848-56. doi: 10.1074/mcp.R115.052902. Epub 2015 Sep 8. Review.

10.

First-year student diary.

Perrett S.

Vet Rec. 2015 Jul 11;177(2):ii. doi: 10.1136/vr.h3680.

PMID:
26160800
11.

Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry.

Zhou XM, Shimanovich U, Herling TW, Wu S, Dobson CM, Knowles TP, Perrett S.

ACS Nano. 2015 Jun 23;9(6):5772-81. doi: 10.1021/acsnano.5b00061. Epub 2015 Jun 8.

12.

Self-Assembly of Amyloid Fibrils That Display Active Enzymes.

Zhou XM, Entwistle A, Zhang H, Jackson AP, Mason TO, Shimanovich U, Knowles TP, Smith AT, Sawyer EB, Perrett S.

ChemCatChem. 2014 Jul;6(7):1961-1968. Epub 2014 Jun 4.

13.

Selective Proteomic Proximity Labeling Assay Using Tyramide (SPPLAT): A Quantitative Method for the Proteomic Analysis of Localized Membrane-Bound Protein Clusters.

Rees JS, Li XW, Perrett S, Lilley KS, Jackson AP.

Curr Protoc Protein Sci. 2015 Apr 1;80:19.27.1-18. doi: 10.1002/0471140864.ps1927s80.

PMID:
25829300
14.

Resonance assignments for the substrate binding domain of Hsp70 chaperone Ssa1 from Saccharomyces cerevisiae.

Hu W, Wu H, Zhang H, Gong W, Perrett S.

Biomol NMR Assign. 2015 Oct;9(2):329-32. doi: 10.1007/s12104-015-9603-5. Epub 2015 Feb 15.

PMID:
25682100
15.

Evolutionarily conserved binding of translationally controlled tumor protein to eukaryotic elongation factor 1B.

Wu H, Gong W, Yao X, Wang J, Perrett S, Feng Y.

J Biol Chem. 2015 Apr 3;290(14):8694-710. doi: 10.1074/jbc.M114.628594. Epub 2015 Jan 29.

16.

A stepped wedge cluster randomized control trial of dried blood spot testing to improve the uptake of hepatitis C antibody testing within UK prisons.

Craine N, Whitaker R, Perrett S, Zou L, Hickman M, Lyons M.

Eur J Public Health. 2015 Apr;25(2):351-7. doi: 10.1093/eurpub/cku096. Epub 2014 Jul 24.

17.

New insights into the DT40 B cell receptor cluster using a proteomic proximity labeling assay.

Li XW, Rees JS, Xue P, Zhang H, Hamaia SW, Sanderson B, Funk PE, Farndale RW, Lilley KS, Perrett S, Jackson AP.

J Biol Chem. 2014 May 23;289(21):14434-47. doi: 10.1074/jbc.M113.529578. Epub 2014 Apr 4.

18.

Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity.

Gong W, Wang J, Perrett S, Feng Y.

J Biol Chem. 2014 Feb 21;289(8):4882-95. doi: 10.1074/jbc.M113.501940. Epub 2013 Dec 30.

19.

Raising public awareness of hepatitis B and C through a testing road show.

Perrett S, Hams P.

Br J Nurs. 2013 Dec 12-2014 Jan 8;22(22):1308, 1310-2.

PMID:
24335868
20.

Complex energy landscape of a giant repeat protein.

Tsytlonok M, Craig PO, Sivertsson E, Serquera D, Perrett S, Best RB, Wolynes PG, Itzhaki LS.

Structure. 2013 Nov 5;21(11):1954-65. doi: 10.1016/j.str.2013.08.028. Epub 2013 Oct 10.

21.

A Roy model study of adapting to being HIV positive.

Perrett SE, Biley FC.

Nurs Sci Q. 2013 Oct;26(4):337-43. doi: 10.1177/0894318413500310.

PMID:
24085671
22.

Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles.

Yao H, Mi S, Gong W, Lin J, Xu N, Perrett S, Xia B, Wang J, Feng Y.

Biochemistry. 2013 Sep 17;52(37):6324-34. doi: 10.1021/bi400690m. Epub 2013 Sep 4.

PMID:
23977882
23.

Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo.

Moran C, Kinsella GK, Zhang ZR, Perrett S, Jones GW.

G3 (Bethesda). 2013 Aug 7;3(8):1409-18. doi: 10.1534/g3.113.007112.

24.

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2.

Xu LQ, Wu S, Buell AK, Cohen SI, Chen LJ, Hu WH, Cusack SA, Itzhaki LS, Zhang H, Knowles TP, Dobson CM, Welland ME, Jones GW, Perrett S.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 25;368(1617):20110410. doi: 10.1098/rstb.2011.0410. Print 2013 May 5.

25.

Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation.

Xu L, Hasin N, Shen M, He J, Xue Y, Zhou X, Perrett S, Song Y, Jones GW.

PLoS Comput Biol. 2013;9(1):e1002896. doi: 10.1371/journal.pcbi.1002896. Epub 2013 Jan 31.

26.

Developing blood borne virus services across prisons in Wales, UK.

Perrett SE, Craine N, Lyons M.

Int J Prison Health. 2013;9(1):31-9. doi: 10.1108/17449201311310788.

PMID:
25758321
27.

Understanding the particokinetics of engineered nanomaterials for safe and effective therapeutic applications.

Zhu M, Perrett S, Nie G.

Small. 2013 May 27;9(9-10):1619-34. doi: 10.1002/smll.201201630. Epub 2012 Dec 6. Review.

PMID:
23225644
28.

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.

Truman AW, Kristjansdottir K, Wolfgeher D, Hasin N, Polier S, Zhang H, Perrett S, Prodromou C, Jones GW, Kron SJ.

Cell. 2012 Dec 7;151(6):1308-18. doi: 10.1016/j.cell.2012.10.051.

29.

Probing the function of the Tyr-Cys cross-link in metalloenzymes by the genetic incorporation of 3-methylthiotyrosine.

Zhou Q, Hu M, Zhang W, Jiang L, Perrett S, Zhou J, Wang J.

Angew Chem Int Ed Engl. 2013 Jan 21;52(4):1203-7. doi: 10.1002/anie.201207229. Epub 2012 Nov 29. No abstract available.

PMID:
23197358
30.

Negotiating uncertainty: the transitional process of adapting to life with HIV.

Perrett SE, Biley FC.

J Assoc Nurses AIDS Care. 2013 May-Jun;24(3):207-18. doi: 10.1016/j.jana.2012.06.007. Epub 2012 Nov 2.

PMID:
23122905
31.

Exploiting amyloid: how and why bacteria use cross-β fibrils.

Sawyer EB, Claessen D, Gras SL, Perrett S.

Biochem Soc Trans. 2012 Aug;40(4):728-34. doi: 10.1042/BST20120013. Review.

PMID:
22817724
32.

Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1.

Gong W, Zhou T, Mo J, Perrett S, Wang J, Feng Y.

J Biol Chem. 2012 Mar 9;287(11):8531-40. doi: 10.1074/jbc.M111.299149. Epub 2012 Jan 12.

33.

The yeast prion protein Ure2: insights into the mechanism of amyloid formation.

Chen LJ, Sawyer EB, Perrett S.

Biochem Soc Trans. 2011 Oct;39(5):1359-64. doi: 10.1042/BST0391359. Review.

PMID:
21936815
34.

Prisoner health: assessing a nurse-led hepatitis C testing clinic.

Perrett SE.

Br J Nurs. 2011 May 27-Jun 9;20(10):611-4.

PMID:
21646992
35.

Chirality of glutathione surface coating affects the cytotoxicity of quantum dots.

Li Y, Zhou Y, Wang HY, Perrett S, Zhao Y, Tang Z, Nie G.

Angew Chem Int Ed Engl. 2011 Jun 20;50(26):5860-4. doi: 10.1002/anie.201008206. Epub 2011 May 12. No abstract available.

PMID:
21567671
36.

The fibrils of Ure2p homologs from Saccharomyces cerevisiae and Saccharoymyces paradoxus have similar cross-β structure in both dried and hydrated forms.

Wang YQ, Bongiovanni M, Gras SL, Perrett S.

J Struct Biol. 2011 Jun;174(3):505-11. doi: 10.1016/j.jsb.2011.03.008. Epub 2011 Mar 17.

PMID:
21419850
37.

Relationship between prion propensity and the rates of individual molecular steps of fibril assembly.

Wang YQ, Buell AK, Wang XY, Welland ME, Dobson CM, Knowles TP, Perrett S.

J Biol Chem. 2011 Apr 8;286(14):12101-7. doi: 10.1074/jbc.M110.208934. Epub 2011 Jan 13.

38.

Studying the effects of chaperones on amyloid fibril formation.

Zhang H, Xu LQ, Perrett S.

Methods. 2011 Mar;53(3):285-94. doi: 10.1016/j.ymeth.2010.11.009. Epub 2010 Dec 7. Review.

PMID:
21144901
39.

Flexibility of the Ure2 prion domain is important for amyloid fibril formation.

Yu Y, Wang HY, Bai M, Perrett S.

Biochem J. 2011 Feb 15;434(1):143-51. doi: 10.1042/BJ20101895.

PMID:
21091436
40.

Deletion of a Ure2 C-terminal prion-inhibiting region promotes the rate of fibril seed formation and alters interaction with Hsp40.

Chen L, Chen LJ, Wang HY, Wang YQ, Perrett S.

Protein Eng Des Sel. 2011 Jan;24(1-2):69-78. doi: 10.1093/protein/gzq100. Epub 2010 Nov 12.

PMID:
21076138
41.

Amyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.

Zhang C, Jackson AP, Zhang ZR, Han Y, Yu S, He RQ, Perrett S.

PLoS One. 2010 Sep 2;5(9). pii: e12529. doi: 10.1371/journal.pone.0012529.

42.

New insights into the molecular mechanism of amyloid formation from cysteine scanning.

Fei L, Perrett S.

Prion. 2010 Jan-Mar;4(1):9-12. Epub 2010 Jan 16.

43.

Effect of nanoparticles on protein folding and fibrillogenesis.

Fei L, Perrett S.

Int J Mol Sci. 2009 Feb;10(2):646-55. doi: 10.3390/ijms10020646. Epub 2009 Feb 20. Review.

44.

Novel glutaredoxin activity of the yeast prion protein Ure2 reveals a native-like dimer within fibrils.

Zhang ZR, Perrett S.

J Biol Chem. 2009 May 22;284(21):14058-67. doi: 10.1074/jbc.M901189200. Epub 2009 Mar 25.

45.

Disulfide bond formation significantly accelerates the assembly of Ure2p fibrils because of the proximity of a potential amyloid stretch.

Fei L, Perrett S.

J Biol Chem. 2009 Apr 24;284(17):11134-41. doi: 10.1074/jbc.M809673200. Epub 2009 Mar 3.

46.

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase.

Zhang H, Loovers HM, Xu LQ, Wang M, Rowling PJ, Itzhaki LS, Gong W, Zhou JM, Jones GW, Perrett S.

Mol Microbiol. 2009 Feb;71(3):702-16. doi: 10.1111/j.1365-2958.2008.06557.x. Epub 2008 Dec 11.

47.

"Restoration" of glutathione transferase activity by single-site mutation of the yeast prion protein Ure2.

Zhang ZR, Bai M, Wang XY, Zhou JM, Perrett S.

J Mol Biol. 2008 Dec 19;384(3):641-51. doi: 10.1016/j.jmb.2008.09.047. Epub 2008 Sep 27.

PMID:
18845158
48.
49.

Intrinsic peroxidase-like activity of ferromagnetic nanoparticles.

Gao L, Zhuang J, Nie L, Zhang J, Zhang Y, Gu N, Wang T, Feng J, Yang D, Perrett S, Yan X.

Nat Nanotechnol. 2007 Sep;2(9):577-83. doi: 10.1038/nnano.2007.260. Epub 2007 Aug 26.

PMID:
18654371
50.

Insights into the mechanism of prion propagation.

Perrett S, Jones GW.

Curr Opin Struct Biol. 2008 Feb;18(1):52-9. doi: 10.1016/j.sbi.2007.12.005. Review.

PMID:
18243685

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