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Items: 1 to 50 of 59

1.

A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes.

Gondry M, Jacques IB, Thai R, Babin M, Canu N, Seguin J, Belin P, Pernodet JL, Moutiez M.

Front Microbiol. 2018 Feb 12;9:46. doi: 10.3389/fmicb.2018.00046. eCollection 2018.

2.

Complete Genome Sequence of Streptomyces sp. TN58, a Producer of Acyl Alpha-l-Rhamnopyranosides.

Najah S, Chong TM, Gerbaud C, Chan KG, Mellouli L, Pernodet JL.

Genome Announc. 2017 Aug 24;5(34). pii: e00828-17. doi: 10.1128/genomeA.00828-17.

3.

Draft Genome Sequence of Streptomyces sp. M1013, a Close Relative of Streptomyces ambofaciens and Streptomyces coelicolor.

Haas D, Gerbaud C, Sahin N, Pernodet JL, Lautru S.

Genome Announc. 2017 Jul 20;5(29). pii: e00643-17. doi: 10.1128/genomeA.00643-17.

4.

Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer.

Thibessard A, Haas D, Gerbaud C, Aigle B, Lautru S, Pernodet JL, Leblond P.

J Biotechnol. 2015 Nov 20;214:117-8. doi: 10.1016/j.jbiotec.2015.09.020. Epub 2015 Sep 26.

PMID:
26410452
5.

Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides.

Li Y, Ducasse R, Zirah S, Blond A, Goulard C, Lescop E, Giraud C, Hartke A, Guittet E, Pernodet JL, Rebuffat S.

ACS Chem Biol. 2015 Nov 20;10(11):2641-9. doi: 10.1021/acschembio.5b00584. Epub 2015 Sep 21.

PMID:
26343290
6.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

7.

The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor.

Boubakri H, Seghezzi N, Duchateau M, Gominet M, Kofroňová O, Benada O, Mazodier P, Pernodet JL.

J Bacteriol. 2015 Nov;197(21):3388-99. doi: 10.1128/JB.00591-15. Epub 2015 Aug 17.

8.

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity.

Jacques IB, Moutiez M, Witwinowski J, Darbon E, Martel C, Seguin J, Favry E, Thai R, Lecoq A, Dubois S, Pernodet JL, Gondry M, Belin P.

Nat Chem Biol. 2015 Sep;11(9):721-7. doi: 10.1038/nchembio.1868. Epub 2015 Aug 3.

PMID:
26236937
9.

Natural combinatorial biosynthesis involving two clusters for the synthesis of three pyrrolamides in Streptomyces netropsis.

Vingadassalon A, Lorieux F, Juguet M, Le Goff G, Gerbaud C, Pernodet JL, Lautru S.

ACS Chem Biol. 2015 Feb 20;10(2):601-10. doi: 10.1021/cb500652n. Epub 2014 Dec 4.

PMID:
25415678
10.

Genome mining of Streptomyces ambofaciens.

Aigle B, Lautru S, Spiteller D, Dickschat JS, Challis GL, Leblond P, Pernodet JL.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):251-63. doi: 10.1007/s10295-013-1379-y. Epub 2013 Nov 21. Review.

PMID:
24258629
11.

Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens.

Nguyen HC, Darbon E, Thai R, Pernodet JL, Lautru S.

Antimicrob Agents Chemother. 2013 Aug;57(8):3836-42. doi: 10.1128/AAC.00512-13. Epub 2013 May 28.

12.

The genome sequence of Streptomyces lividans 66 reveals a novel tRNA-dependent peptide biosynthetic system within a metal-related genomic island.

Cruz-Morales P, Vijgenboom E, Iruegas-Bocardo F, Girard G, Yáñez-Guerra LA, Ramos-Aboites HE, Pernodet JL, Anné J, van Wezel GP, Barona-Gómez F.

Genome Biol Evol. 2013;5(6):1165-75. doi: 10.1093/gbe/evt082.

13.

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways.

Belin P, Moutiez M, Lautru S, Seguin J, Pernodet JL, Gondry M.

Nat Prod Rep. 2012 Sep;29(9):961-79. doi: 10.1039/c2np20010d. Epub 2012 Jul 3. Review.

PMID:
22751625
14.

A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate.

Lautru S, Song L, Demange L, Lombès T, Galons H, Challis GL, Pernodet JL.

Angew Chem Int Ed Engl. 2012 Jul 23;51(30):7454-8. doi: 10.1002/anie.201201445. Epub 2012 Jun 15. No abstract available.

PMID:
22707277
15.

Nonribosomal peptide synthesis in animals: the cyclodipeptide synthase of Nematostella.

Seguin J, Moutiez M, Li Y, Belin P, Lecoq A, Fonvielle M, Charbonnier JB, Pernodet JL, Gondry M.

Chem Biol. 2011 Nov 23;18(11):1362-8. doi: 10.1016/j.chembiol.2011.09.010.

16.

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis.

Sauguet L, Moutiez M, Li Y, Belin P, Seguin J, Le Du MH, Thai R, Masson C, Fonvielle M, Pernodet JL, Charbonnier JB, Gondry M.

Nucleic Acids Res. 2011 May;39(10):4475-89. doi: 10.1093/nar/gkr027. Epub 2011 Feb 3.

17.

Regulation of the biosynthesis of the macrolide antibiotic spiramycin in Streptomyces ambofaciens.

Karray F, Darbon E, Nguyen HC, Gagnat J, Pernodet JL.

J Bacteriol. 2010 Nov;192(21):5813-21. doi: 10.1128/JB.00712-10. Epub 2010 Sep 3.

18.

Glycosylation steps during spiramycin biosynthesis in Streptomyces ambofaciens: involvement of three glycosyltransferases and their interplay with two auxiliary proteins.

Nguyen HC, Karray F, Lautru S, Gagnat J, Lebrihi A, Huynh TD, Pernodet JL.

Antimicrob Agents Chemother. 2010 Jul;54(7):2830-9. doi: 10.1128/AAC.01602-09. Epub 2010 May 3.

19.

Transcriptional regulation of the novobiocin biosynthetic gene cluster.

Dangel V, Härle J, Goerke C, Wolz C, Gust B, Pernodet JL, Heide L.

Microbiology. 2009 Dec;155(Pt 12):4025-35. doi: 10.1099/mic.0.032649-0. Epub 2009 Sep 17.

PMID:
19762445
20.

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes.

Gondry M, Sauguet L, Belin P, Thai R, Amouroux R, Tellier C, Tuphile K, Jacquet M, Braud S, Courçon M, Masson C, Dubois S, Lautru S, Lecoq A, Hashimoto S, Genet R, Pernodet JL.

Nat Chem Biol. 2009 Jun;5(6):414-20. doi: 10.1038/nchembio.175.

PMID:
19430487
21.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.

Belin P, Le Du MH, Fielding A, Lequin O, Jacquet M, Charbonnier JB, Lecoq A, Thai R, Courçon M, Masson C, Dugave C, Genet R, Pernodet JL, Gondry M.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7426-31. doi: 10.1073/pnas.0812191106. Epub 2009 Apr 22.

22.

An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

Juguet M, Lautru S, Francou FX, Nezbedová S, Leblond P, Gondry M, Pernodet JL.

Chem Biol. 2009 Apr 24;16(4):421-31. doi: 10.1016/j.chembiol.2009.03.010.

23.

Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.

Karray F, Darbon E, Oestreicher N, Dominguez H, Tuphile K, Gagnat J, Blondelet-Rouault MH, Gerbaud C, Pernodet JL.

Microbiology. 2007 Dec;153(Pt 12):4111-22.

PMID:
18048924
24.
25.

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.

Barona-Gómez F, Lautru S, Francou FX, Leblond P, Pernodet JL, Challis GL.

Microbiology. 2006 Nov;152(Pt 11):3355-66.

PMID:
17074905
26.

Evolution of the terminal regions of the Streptomyces linear chromosome.

Choulet F, Aigle B, Gallois A, Mangenot S, Gerbaud C, Truong C, Francou FX, Fourrier C, Guérineau M, Decaris B, Barbe V, Pernodet JL, Leblond P.

Mol Biol Evol. 2006 Dec;23(12):2361-9. Epub 2006 Sep 6.

PMID:
16956972
27.

Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.

Choulet F, Gallois A, Aigle B, Mangenot S, Gerbaud C, Truong C, Francou FX, Borges F, Fourrier C, Guérineau M, Decaris B, Barbe V, Pernodet JL, Leblond P.

J Bacteriol. 2006 Sep;188(18):6599-610.

28.

Construction and testing of a bacterial luciferase reporter gene system for in vivo measurement of nonsense suppression in Streptomyces.

Weiser J, Buriánková K, Kalachová L, Branny P, Pernodet JL.

Folia Microbiol (Praha). 2006;51(1):62-4.

PMID:
16821714
29.

Excisable cassettes: new tools for functional analysis of Streptomyces genomes.

Raynal A, Karray F, Tuphile K, Darbon-Rongère E, Pernodet JL.

Appl Environ Microbiol. 2006 Jul;72(7):4839-44.

30.

Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis.

Madsen CT, Jakobsen L, Buriánková K, Doucet-Populaire F, Pernodet JL, Douthwaite S.

J Biol Chem. 2005 Nov 25;280(47):38942-7. Epub 2005 Sep 20.

31.

Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.

Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P.

Antimicrob Agents Chemother. 2004 Feb;48(2):575-88.

32.

Molecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complex.

Buriánková K, Doucet-Populaire F, Dorson O, Gondran A, Ghnassia JC, Weiser J, Pernodet JL.

Antimicrob Agents Chemother. 2004 Jan;48(1):143-50.

33.

Conjugal immunity of Streptomyces strains carrying the integrative element pSAM2 is due to the pif gene (pSAM2 immunity factor).

Possoz C, Gagnat J, Sezonov G, Guérineau M, Pernodet JL.

Mol Microbiol. 2003 Mar;47(5):1385-93.

34.

Natural and acquired macrolide resistance in mycobacteria.

Doucet-Populaire F, Buriánková K, Weiser J, Pernodet JL.

Curr Drug Targets Infect Disord. 2002 Dec;2(4):355-70. Review.

PMID:
12570741
35.

Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.

Courtois S, Cappellano CM, Ball M, Francou FX, Normand P, Helynck G, Martinez A, Kolvek SJ, Hopke J, Osburne MS, August PR, Nalin R, Guérineau M, Jeannin P, Simonet P, Pernodet JL.

Appl Environ Microbiol. 2003 Jan;69(1):49-55.

36.
37.

Characterization of the attP site of the integrative element pSAM2 from Streptomyces ambofaciens.

Raynal A, Friedmann A, Tuphile K, Guerineau M, Pernodet JL.

Microbiology. 2002 Jan;148(Pt 1):61-7.

PMID:
11782499
38.

The integrative element pSAM2 from Streptomyces: kinetics and mode of conjugal transfer.

Possoz C, Ribard C, Gagnat J, Pernodet JL, Guérineau M.

Mol Microbiol. 2001 Oct;42(1):159-66.

39.

KorSA from the Streptomyces integrative element pSAM2 is a central transcriptional repressor: target genes and binding sites.

Sezonov G, Possoz C, Friedmann A, Pernodet JL, Guérineau M.

J Bacteriol. 2000 Mar;182(5):1243-50.

40.

Dispensable ribosomal resistance to spiramycin conferred by srmA in the spiramycin producer Streptomyces ambofaciens.

Pernodet JL, Gourmelen A, Blondelet-Rouault MH, Cundliffe E.

Microbiology. 1999 Sep;145 ( Pt 9):2355-64.

PMID:
10517588
41.

Characterization of a glycosyl transferase inactivating macrolides, encoded by gimA from Streptomyces ambofaciens.

Gourmelen A, Blondelet-Rouault MH, Pernodet JL.

Antimicrob Agents Chemother. 1998 Oct;42(10):2612-9.

42.

Structure of the chromosomal insertion site for pSAM2: functional analysis in Escherichia coli.

Raynal A, Tuphile K, Gerbaud C, Luther T, Guérineau M, Pernodet JL.

Mol Microbiol. 1998 Apr;28(2):333-42.

43.

Replicase, excisionase, and integrase genes of the Streptomyces element pSAM2 constitute an operon positively regulated by the pra gene.

Sezonov G, Duchêne AM, Friedmann A, Guérineau M, Pernodet JL.

J Bacteriol. 1998 Jun;180(12):3056-61.

44.

Antibiotic resistance gene cassettes derived from the omega interposon for use in E. coli and Streptomyces.

Blondelet-Rouault MH, Weiser J, Lebrihi A, Branny P, Pernodet JL.

Gene. 1997 May 6;190(2):315-7.

PMID:
9197550
45.

Complete conversion of antibiotic precursor to pristinamycin IIA by overexpression of Streptomyces pristinaespiralis biosynthetic genes.

Sezonov G, Blanc V, Bamas-Jacques N, Friedmann A, Pernodet JL, Guérineau M.

Nat Biotechnol. 1997 Apr;15(4):349-53.

PMID:
9094136
46.
47.

Characterization of pra, a gene for replication control in pSAM2, the integrating element of Streptomyces ambofaciens.

Sezonov G, Hagège J, Pernodet JL, Friedmann A, Guérineau M.

Mol Microbiol. 1995 Aug;17(3):533-44.

PMID:
8559072
48.

Cloning of Frankia species putative tRNA(Pro) genes and their efficacy for pSAM2 site-specific integration in Streptomyces lividans.

Alegre MT, Cournoyer B, Mesas JM, Guérineau M, Normand P, Pernodet JL.

Appl Environ Microbiol. 1994 Dec;60(12):4279-83.

49.

Identification of a gene encoding the replication initiator protein of the Streptomyces integrating element, pSAM2.

Hagège J, Boccard F, Smokvina T, Pernodet JL, Friedmann A, Guérineau M.

Plasmid. 1994 Mar;31(2):166-83.

PMID:
8029324
50.

Mode and origin of replication of pSAM2, a conjugative integrating element of Streptomyces ambofaciens.

Hagège J, Pernodet JL, Friedmann A, Guérineau M.

Mol Microbiol. 1993 Nov;10(4):799-812.

PMID:
7934842

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