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Risk of Leukemia after Dengue Virus Infection: A Population-Based Cohort Study.

Chien YW, Wang CC, Wang YP, Lee CY, Perng GC.

Cancer Epidemiol Biomarkers Prev. 2020 Mar;29(3):558-564. doi: 10.1158/1055-9965.EPI-19-1214. Epub 2020 Feb 12.


Dynamic changes of soluble ST2 levels predicted fatality and were involved in coagulopathy in dengue fever in the elderly.

Hsieh CC, Hong MY, Ho TS, Liu CC, Perng GC, Chuang CC.

PLoS Negl Trop Dis. 2019 Dec 26;13(12):e0007974. doi: 10.1371/journal.pntd.0007974. eCollection 2019 Dec.


Low seroprevalence of Zika virus infection among adults in Southern Taiwan.

Chien YW, Ho TC, Huang PW, Ko NY, Ko WC, Perng GC.

BMC Infect Dis. 2019 Oct 23;19(1):884. doi: 10.1186/s12879-019-4491-4.


Identification and characterization of permissive cells to dengue virus infection in human hematopoietic stem and progenitor cells.

Hsu AY, Ho TC, Lai ML, Tan SS, Chen TY, Lee M, Chien YW, Chen YP, Perng GC.

Transfusion. 2019 Sep;59(9):2938-2951. doi: 10.1111/trf.15416. Epub 2019 Jun 28.


Seroepidemiology of dengue virus infection among adults during the ending phase of a severe dengue epidemic in southern Taiwan, 2015.

Chien YW, Huang HM, Ho TC, Tseng FC, Ko NY, Ko WC, Perng GC.

BMC Infect Dis. 2019 Apr 24;19(1):338. doi: 10.1186/s12879-019-3946-y.


Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage.

Chao CH, Wu WC, Lai YC, Tsai PJ, Perng GC, Lin YS, Yeh TM.

PLoS Pathog. 2019 Apr 22;15(4):e1007625. doi: 10.1371/journal.ppat.1007625. eCollection 2019 Apr.


Seroprevalence of Zika and Dengue Virus Antibodies among Migrant Workers, Taiwan, 2017.

Perng GC, Ho TC, Shih HI, Lee CH, Huang PW, Chung CH, Ko NY, Ko WC, Chien YW.

Emerg Infect Dis. 2019 Apr;25(4):814-816. doi: 10.3201/eid2504.181449.


Human glucose-regulated protein 78 modulates intracellular production and secretion of nonstructural protein 1 of dengue virus.

Songprakhon P, Limjindaporn T, Perng GC, Puttikhunt C, Thaingtamtanha T, Dechtawewat T, Saitornuang S, Uthaipibull C, Thongsima S, Yenchitsomanus PT, Malasit P, Noisakran S.

J Gen Virol. 2018 Oct;99(10):1391-1406. doi: 10.1099/jgv.0.001134. Epub 2018 Aug 10.


Minocycline suppresses dengue virus replication by down-regulation of macrophage migration inhibitory factor-induced autophagy.

Lai YC, Chuang YC, Chang CP, Lin YS, Perng GC, Wu HC, Hsieh SL, Yeh TM.

Antiviral Res. 2018 Jul;155:28-38. doi: 10.1016/j.antiviral.2018.05.002. Epub 2018 May 9.


Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability.

Chen HR, Chao CH, Liu CC, Ho TS, Tsai HP, Perng GC, Lin YS, Wang JR, Yeh TM.

PLoS Pathog. 2018 Apr 27;14(4):e1007033. doi: 10.1371/journal.ppat.1007033. eCollection 2018 Apr.


Prolonged persistence of IgM against dengue virus detected by commonly used commercial assays.

Chien YW, Liu ZH, Tseng FC, Ho TC, Guo HR, Ko NY, Ko WC, Perng GC.

BMC Infect Dis. 2018 Apr 2;18(1):156. doi: 10.1186/s12879-018-3058-0.


Symptoms associated with adverse dengue fever prognoses at the time of reporting in the 2015 dengue outbreak in Taiwan.

Yeh CY, Chen PL, Chuang KT, Shu YC, Chien YW, Perng GC, Ko WC, Ko NY.

PLoS Negl Trop Dis. 2017 Dec 6;11(12):e0006091. doi: 10.1371/journal.pntd.0006091. eCollection 2017 Dec.


High estimated prevalence of asymptomatic dengue viremia in blood donors during a dengue epidemic in southern Taiwan, 2015.

Chien YW, Shu YC, Chuang KT, Yeh CY, Ko WC, Ko NY, Perng GC.

Transfusion. 2017 Nov;57(11):2649-2656. doi: 10.1111/trf.14281. Epub 2017 Aug 24.


A bead-based immunofluorescence-assay on a microfluidic dielectrophoresis platform for rapid dengue virus detection.

Iswardy E, Tsai TC, Cheng IF, Ho TC, Perng GC, Chang HC.

Biosens Bioelectron. 2017 Sep 15;95:174-180. doi: 10.1016/j.bios.2017.04.011. Epub 2017 Apr 12. Erratum in: Biosens Bioelectron. 2017 Nov 15;97:400.


Transient Monocytosis Subjugates Low Platelet Count in Adult Dengue Patients.

Tsai JJ, Chang JS, Chang K, Chen PC, Liu LT, Ho TC, Tan SS, Chien YW, Lo YC, Perng GC.

Biomed Hub. 2017 Mar 3;2(1):1-16. doi: 10.1159/000457785. eCollection 2017 Jan-Apr.


Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization.

Wu YW, Mettling C, Wu SR, Yu CY, Perng GC, Lin YS, Lin YL.

Sci Rep. 2016 Aug 25;6:32243. doi: 10.1038/srep32243.


Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy.

Chen HR, Chuang YC, Lin YS, Liu HS, Liu CC, Perng GC, Yeh TM.

PLoS Negl Trop Dis. 2016 Jul 13;10(7):e0004828. doi: 10.1371/journal.pntd.0004828. eCollection 2016 Jul.


Novel concept on antiviral strategies to dengue.

Lo YC, Perng GC.

Curr Opin Virol. 2016 Jun;18:97-108. doi: 10.1016/j.coviro.2016.05.009. Epub 2016 Jun 7. Review.


Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology.

Keller AC, Badani H, McClatchey PM, Baird NL, Bowlin JL, Bouchard R, Perng GC, Reusch JE, Kaufer BB, Gilden D, Shahzad A, Kennedy PG, Cohrs RJ.

J Neurovirol. 2016 Oct;22(5):674-682. Epub 2016 May 31.


Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells.

Clark KB, Hsiao HM, Bassit L, Crowe JE Jr, Schinazi RF, Perng GC, Villinger F.

Virology. 2016 Jun;493:162-72. doi: 10.1016/j.virol.2016.03.024. Epub 2016 Apr 6.


Infectious dengue vesicles derived from CD61+ cells in acute patient plasma exhibited a diaphanous appearance.

Hsu AY, Wu SR, Tsai JJ, Chen PL, Chen YP, Chen TY, Lo YC, Ho TC, Lee M, Chen MT, Chiu YC, Perng GC.

Sci Rep. 2015 Dec 11;5:17990. doi: 10.1038/srep17990.


Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis.

Jester JV, Morishige N, BenMohamed L, Brown DJ, Osorio N, Hsiang C, Perng GC, Jones C, Wechsler SL.

Cornea. 2016 Jan;35(1):81-8. doi: 10.1097/ICO.0000000000000666.


Biomarkers of severe dengue disease - a review.

John DV, Lin YS, Perng GC.

J Biomed Sci. 2015 Oct 14;22:83. doi: 10.1186/s12929-015-0191-6. Review.


Current neurological observations and complications of dengue virus infection.

Solbrig MV, Perng GC.

Curr Neurol Neurosci Rep. 2015 Jun;15(6):29. doi: 10.1007/s11910-015-0550-4. Review.


Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus.

Perng GC, Osorio N, Jiang X, Geertsema R, Hsiang C, Brown D, BenMohamed L, Wechsler SL.

Curr Eye Res. 2016;41(3):284-91. doi: 10.3109/02713683.2015.1020172. Epub 2015 Apr 10.


Neuropathogenesis of Japanese encephalitis in a primate model.

Myint KS, Kipar A, Jarman RG, Gibbons RV, Perng GC, Flanagan B, Mongkolsirichaikul D, Van Gessel Y, Solomon T.

PLoS Negl Trop Dis. 2014 Aug 7;8(8):e2980. doi: 10.1371/journal.pntd.0002980. eCollection 2014 Aug.


Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation.

Kwissa M, Nakaya HI, Onlamoon N, Wrammert J, Villinger F, Perng GC, Yoksan S, Pattanapanyasat K, Chokephaibulkit K, Ahmed R, Pulendran B.

Cell Host Microbe. 2014 Jul 9;16(1):115-27. doi: 10.1016/j.chom.2014.06.001. Epub 2014 Jun 26.


Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes.

Tsetsarkin KA, Chen R, Yun R, Rossi SL, Plante KS, Guerbois M, Forrester N, Perng GC, Sreekumar E, Leal G, Huang J, Mukhopadhyay S, Weaver SC.

Nat Commun. 2014 Jun 16;5:4084. doi: 10.1038/ncomms5084.


Tranylcypromine reduces herpes simplex virus 1 infection in mice.

Yao HW, Lin PH, Shen FH, Perng GC, Tung YY, Hsu SM, Chen SH.

Antimicrob Agents Chemother. 2014 May;58(5):2807-15. doi: 10.1128/AAC.02617-13. Epub 2014 Mar 3.


Role of cognitive parameters in dengue hemorrhagic fever and dengue shock syndrome.

Tsai JJ, Chokephaibulkit K, Chen PC, Liu LT, Hsiao HM, Lo YC, Perng GC.

J Biomed Sci. 2013 Dec 5;20:88. doi: 10.1186/1423-0127-20-88. Review.


Can non-human primates serve as models for investigating dengue disease pathogenesis?

Clark KB, Onlamoon N, Hsiao HM, Perng GC, Villinger F.

Front Microbiol. 2013 Oct 11;4:305. doi: 10.3389/fmicb.2013.00305. Review.


Mortality from septic shock in a dengue infected patient: a case report.

Tsai JJ, Hsieh MH, Liu LT, Hsiao HM, Perng GC.

Southeast Asian J Trop Med Public Health. 2013 Jul 4;44(4):623-9.


Challenges for the formulation of a universal vaccine against dengue.

Chokephaibulkit K, Perng GC.

Exp Biol Med (Maywood). 2013 May;238(5):566-78. doi: 10.1177/1535370212473703. Review.


Immunologic hypo- or non-responder in natural dengue virus infection.

Perng GC, Chokephaibulkit K.

J Biomed Sci. 2013 May 31;20:34. doi: 10.1186/1423-0127-20-34.


Multiploid CD61+ cells are the pre-dominant cell lineage infected during acute dengue virus infection in bone marrow.

Clark KB, Noisakran S, Onlamoon N, Hsiao HM, Roback J, Villinger F, Ansari AA, Perng GC.

PLoS One. 2012;7(12):e52902. doi: 10.1371/journal.pone.0052902. Epub 2012 Dec 27.


Role of Bone Marrow in Pathogenesis of Viral Infections.

Perng GC.

J Bone Marrow Res. 2012 Dec 29;1. pii: 104. No abstract available.


Role of CD61+ cells in thrombocytopenia of dengue patients.

Noisakran S, Onlamoon N, Pattanapanyasat K, Hsiao HM, Songprakhon P, Angkasekwinai N, Chokephaibulkit K, Villinger F, Ansari AA, Perng GC.

Int J Hematol. 2012 Nov;96(5):600-10. doi: 10.1007/s12185-012-1175-x. Epub 2012 Sep 18.


Role of microparticles in dengue virus infection and its impact on medical intervention strategies.

Bargeron Clark K, Hsiao HM, Noisakran S, Tsai JJ, Perng GC.

Yale J Biol Med. 2012 Mar;85(1):3-18. Epub 2012 Mar 29. Review.


The importance of hematopoietic progenitor cells in dengue.

Tsai JJ, Liu LT, Chang K, Wang SH, Hsiao HM, Clark KB, Perng GC.

Ther Adv Hematol. 2012 Feb;3(1):59-71. doi: 10.1177/2040620711417660.


Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans.

Wrammert J, Onlamoon N, Akondy RS, Perng GC, Polsrila K, Chandele A, Kwissa M, Pulendran B, Wilson PC, Wittawatmongkol O, Yoksan S, Angkasekwinai N, Pattanapanyasat K, Chokephaibulkit K, Ahmed R.

J Virol. 2012 Mar;86(6):2911-8. doi: 10.1128/JVI.06075-11. Epub 2012 Jan 11.


Infection of bone marrow cells by dengue virus in vivo.

Noisakran S, Onlamoon N, Hsiao HM, Clark KB, Villinger F, Ansari AA, Perng GC.

Exp Hematol. 2012 Mar;40(3):250-259.e4. doi: 10.1016/j.exphem.2011.11.011. Epub 2011 Dec 19.


Frequency alterations in key innate immune cell components in the peripheral blood of dengue patients detected by FACS analysis.

Tsai JJ, Jen YH, Chang JS, Hsiao HM, Noisakran S, Perng GC.

J Innate Immun. 2011;3(5):530-40. doi: 10.1159/000322904. Epub 2011 Feb 18.


Role of infection in neurologic and psychiatric diseases.

Solbrig MV, Perng GC.

Interdiscip Perspect Infect Dis. 2010;2010:645834. doi: 10.1155/2010/645834. Epub 2010 Jul 1. No abstract available.


Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycle.

Perng GC, Jones C.

Interdiscip Perspect Infect Dis. 2010;2010:262415. doi: 10.1155/2010/262415. Epub 2010 Feb 15.


Dengue virus-induced hemorrhage in a nonhuman primate model.

Onlamoon N, Noisakran S, Hsiao HM, Duncan A, Villinger F, Ansari AA, Perng GC.

Blood. 2010 Mar 4;115(9):1823-34. doi: 10.1182/blood-2009-09-242990. Epub 2009 Dec 30.


Cells in dengue virus infection in vivo.

Noisakran S, Onlamoon N, Songprakhon P, Hsiao HM, Chokephaibulkit K, Perng GC.

Adv Virol. 2010;2010:164878. doi: 10.1155/2010/164878. Epub 2010 Aug 12.


A re-evaluation of the mechanisms leading to dengue hemorrhagic fever.

Noisakran S, Chokephaibulkit K, Songprakhon P, Onlamoon N, Hsiao HM, Villinger F, Ansari A, Perng GC.

Ann N Y Acad Sci. 2009 Sep;1171 Suppl 1:E24-35. doi: 10.1111/j.1749-6632.2009.05050.x.


ICAM-5 modulates cytokine/chemokine production in the CNS during the course of herpes simplex virus type 1 infection.

Tse MC, Lane C, Mott K, Onlamoon N, Hsiao HM, Perng GC.

J Neuroimmunol. 2009 Aug 18;213(1-2):12-9. doi: 10.1016/j.jneuroim.2009.06.007. Epub 2009 Jul 9.


Identification of a novel herpes simplex virus type 1 transcript and protein (AL3) expressed during latency.

Jaber T, Henderson G, Li S, Perng GC, Carpenter D, Wechsler SL, Jones C.

J Gen Virol. 2009 Oct;90(Pt 10):2342-2352. doi: 10.1099/vir.0.013318-0. Epub 2009 Jul 1.


Detection of dengue virus in platelets isolated from dengue patients.

Noisakran S, Gibbons RV, Songprakhon P, Jairungsri A, Ajariyakhajorn C, Nisalak A, Jarman RG, Malasit P, Chokephaibulkit K, Perng GC.

Southeast Asian J Trop Med Public Health. 2009 Mar;40(2):253-62.


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