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Items: 1 to 50 of 114

1.

Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors.

Shapiguzov A, Vainonen JP, Hunter K, Tossavainen H, Tiwari A, Järvi S, Hellman M, Aarabi F, Alseekh S, Wybouw B, Van Der Kelen K, Nikkanen L, Krasensky-Wrzaczek J, Sipari N, Keinänen M, Tyystjärvi E, Rintamäki E, De Rybel B, Salojärvi J, van Breusegem F, Fernie AR, Brosché M, Permi P, Aro EM, Wrzaczek M, Kangasjarvi J.

Elife. 2019 Feb 15;8. pii: e43284. doi: 10.7554/eLife.43284. [Epub ahead of print]

2.

Alternative Biosynthetic Starter Units Enhance the Structural Diversity of Cyanobacterial Lipopeptides.

Mareš J, Hájek J, Urajová P, Kust A, Jokela J, Saurav K, Galica T, Čapková K, Mattila A, Haapaniemi E, Permi P, Mysterud I, Skulberg OM, Karlsen J, Fewer DP, Sivonen K, Tønnesen HH, Hrouzek P.

Appl Environ Microbiol. 2019 Feb 6;85(4). pii: e02675-18. doi: 10.1128/AEM.02675-18. Print 2019 Feb 15.

PMID:
30504214
3.

Structural and Functional Insights Into Lysostaphin-Substrate Interaction.

Tossavainen H, Raulinaitis V, Kauppinen L, Pentikäinen U, Maaheimo H, Permi P.

Front Mol Biosci. 2018 Jul 3;5:60. doi: 10.3389/fmolb.2018.00060. eCollection 2018.

4.

Maternal Inheritance of a Recessive RBP4 Defect in Canine Congenital Eye Disease.

Kaukonen M, Woods S, Ahonen S, Lemberg S, Hellman M, Hytönen MK, Permi P, Glaser T, Lohi H.

Cell Rep. 2018 May 29;23(9):2643-2652. doi: 10.1016/j.celrep.2018.04.118.

5.

Discovery of a Pederin Family Compound in a Nonsymbiotic Bloom-Forming Cyanobacterium.

Kust A, Mareš J, Jokela J, Urajová P, Hájek J, Saurav K, Voráčová K, Fewer DP, Haapaniemi E, Permi P, Řeháková K, Sivonen K, Hrouzek P.

ACS Chem Biol. 2018 May 18;13(5):1123-1129. doi: 10.1021/acschembio.7b01048. Epub 2018 May 2.

PMID:
29570981
6.

Characterization of sulfhydryl oxidase from Aspergillus tubingensis.

Nivala O, Faccio G, Arvas M, Permi P, Buchert J, Kruus K, Mattinen ML.

BMC Biochem. 2017 Dec 8;18(1):15. doi: 10.1186/s12858-017-0090-4.

7.

The swinholide biosynthetic gene cluster from a terrestrial cyanobacterium Nostoc sp. UHCC 0450.

Humisto A, Jokela J, Liu L, Wahlsten M, Wang H, Permi P, Machado JP, Antunes A, Fewer DP, Sivonen K.

Appl Environ Microbiol. 2017 Nov 17. pii: AEM.02321-17. doi: 10.1128/AEM.02321-17. [Epub ahead of print]

8.

Dynamic Stabilization of the Ligand-Metal Interface in Atomically Precise Gold Nanoclusters Au68 and Au144 Protected by meta-Mercaptobenzoic Acid.

Tero TR, Malola S, Koncz B, Pohjolainen E, Lautala S, Mustalahti S, Permi P, Groenhof G, Pettersson M, Häkkinen H.

ACS Nano. 2017 Dec 26;11(12):11872-11879. doi: 10.1021/acsnano.7b07787. Epub 2017 Nov 21.

PMID:
29136363
9.

Structural Tuning and Conformational Stability of Aromatic Oligoamide Foldamers.

Annala R, Suhonen A, Laakkonen H, Permi P, Nissinen M.

Chemistry. 2017 Nov 21;23(65):16671-16680. doi: 10.1002/chem.201703985. Epub 2017 Nov 3.

PMID:
29105164
10.

Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543.

Jokela J, Heinilä LMP, Shishido TK, Wahlsten M, Fewer DP, Fiore MF, Wang H, Haapaniemi E, Permi P, Sivonen K.

Front Microbiol. 2017 Oct 9;8:1963. doi: 10.3389/fmicb.2017.01963. eCollection 2017.

11.

Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family.

Raulinaitis V, Tossavainen H, Aitio O, Juuti JT, Hiramatsu K, Kontinen V, Permi P.

Sci Rep. 2017 Jul 20;7(1):6020. doi: 10.1038/s41598-017-06135-w.

12.

Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing.

Seppälä J, Bernardi RC, Haataja TJK, Hellman M, Pentikäinen OT, Schulten K, Permi P, Ylänne J, Pentikäinen U.

Sci Rep. 2017 Jun 26;7(1):4218. doi: 10.1038/s41598-017-04441-x.

13.

1H, 13C and 15N NMR chemical shift assignments of A. thaliana RCD1 RST.

Tossavainen H, Hellman M, Vainonen JP, Kangasjärvi J, Permi P.

Biomol NMR Assign. 2017 Oct;11(2):207-210. doi: 10.1007/s12104-017-9749-4. Epub 2017 Jun 7.

PMID:
28593560
14.
15.

1H, 13C and 15N resonance assignments of the new lysostaphin family endopeptidase catalytic domain from Staphylococcus aureus.

Raulinaitis V, Tossavainen H, Aitio O, Seppala R, Permi P.

Biomol NMR Assign. 2017 Apr;11(1):69-73. doi: 10.1007/s12104-016-9722-7. Epub 2016 Dec 9.

PMID:
27943001
16.

A novel intrinsically disordered outer membrane lipoprotein of Aggregatibacter actinomycetemcomitans binds various cytokines and plays a role in biofilm response to interleukin-1β and interleukin-8.

Ahlstrand T, Tuominen H, Beklen A, Torittu A, Oscarsson J, Sormunen R, Pöllänen MT, Permi P, Ihalin R.

Virulence. 2017 Feb 17;8(2):115-134. doi: 10.1080/21505594.2016.1216294. Epub 2016 Jul 26.

17.

Structural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2.

Tossavainen H, Aitio O, Hellman M, Saksela K, Permi P.

J Biol Chem. 2016 Jul 29;291(31):16307-17. doi: 10.1074/jbc.M116.732412. Epub 2016 Jun 6.

18.

Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity.

Mätlik K, Yu LY, Eesmaa A, Hellman M, Lindholm P, Peränen J, Galli E, Anttila J, Saarma M, Permi P, Airavaara M, Arumäe U.

Cell Death Dis. 2015 Dec 31;6:e2032. doi: 10.1038/cddis.2015.371.

19.

Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function.

Laitaoja M, Tossavainen H, Pihlajamaa T, Valjakka J, Viiri K, Lohi O, Permi P, Jänis J.

Protein Sci. 2016 Mar;25(3):572-86. doi: 10.1002/pro.2849. Epub 2015 Dec 10.

20.

Antifungal activity improved by coproduction of cyclodextrins and anabaenolysins in Cyanobacteria.

Shishido TK, Jokela J, Kolehmainen CT, Fewer DP, Wahlsten M, Wang H, Rouhiainen L, Rizzi E, De Bellis G, Permi P, Sivonen K.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13669-74. doi: 10.1073/pnas.1510432112. Epub 2015 Oct 16.

21.

Hydrophobic pocket targeting probes for enteroviruses.

Martikainen M, Salorinne K, Lahtinen T, Malola S, Permi P, Häkkinen H, Marjomäki V.

Nanoscale. 2015 Nov 7;7(41):17457-67. doi: 10.1039/c5nr04139b.

PMID:
26440968
22.

Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21.

Seppälä J, Tossavainen H, Rodic N, Permi P, Pentikäinen U, Ylänne J.

PLoS One. 2015 Aug 31;10(8):e0136969. doi: 10.1371/journal.pone.0136969. eCollection 2015.

23.

H(N), N, C(α), C(β) and C' assignments of the intrinsically disordered C-terminus of human adenosine A2A receptor.

Tossavainen H, Hellman M, Piirainen H, Jaakola VP, Permi P.

Biomol NMR Assign. 2015 Oct;9(2):403-6. doi: 10.1007/s12104-015-9618-y. Epub 2015 May 8.

PMID:
25952762
24.

Antifungal compounds from cyanobacteria.

Shishido TK, Humisto A, Jokela J, Liu L, Wahlsten M, Tamrakar A, Fewer DP, Permi P, Andreote AP, Fiore MF, Sivonen K.

Mar Drugs. 2015 Apr 13;13(4):2124-40. doi: 10.3390/md13042124.

25.

Human adenosine A2A receptor binds calmodulin with high affinity in a calcium-dependent manner.

Piirainen H, Hellman M, Tossavainen H, Permi P, Kursula P, Jaakola VP.

Biophys J. 2015 Feb 17;108(4):903-917. doi: 10.1016/j.bpj.2014.12.036.

26.

Pseudoaeruginosins, nonribosomal peptides in Nodularia spumigena.

Liu L, Budnjo A, Jokela J, Haug BE, Fewer DP, Wahlsten M, Rouhiainen L, Permi P, Fossen T, Sivonen K.

ACS Chem Biol. 2015 Mar 20;10(3):725-33. doi: 10.1021/cb5004306. Epub 2014 Dec 5.

PMID:
25419633
27.

4-Methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides.

Liu L, Jokela J, Herfindal L, Wahlsten M, Sinkkonen J, Permi P, Fewer DP, Døskeland SO, Sivonen K.

ACS Chem Biol. 2014 Nov 21;9(11):2646-55. doi: 10.1021/cb500436p. Epub 2014 Sep 25.

PMID:
25203327
28.

Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN.

Liu L, Jokela J, Wahlsten M, Nowruzi B, Permi P, Zhang YZ, Xhaard H, Fewer DP, Sivonen K.

J Nat Prod. 2014 Aug 22;77(8):1784-90. doi: 10.1021/np500106w.

PMID:
25069058
29.

Chimeric Avidin--NMR structure and dynamics of a 56 kDa homotetrameric thermostable protein.

Tossavainen H, Kukkurainen S, Määttä JA, Kähkönen N, Pihlajamaa T, Hytönen VP, Kulomaa MS, Permi P.

PLoS One. 2014 Jun 24;9(6):e100564. doi: 10.1371/journal.pone.0100564. eCollection 2014.

30.

Secondary metabolite from Nostoc XPORK14A inhibits photosynthesis and growth of Synechocystis PCC 6803.

Shunmugam S, Jokela J, Wahlsten M, Battchikova N, Ateeq ur Rehman, Vass I, Karonen M, Sinkkonen J, Permi P, Sivonen K, Aro EM, Allahverdiyeva Y.

Plant Cell Environ. 2014 Jun;37(6):1371-81.

PMID:
24895757
31.

Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway.

Vestola J, Shishido TK, Jokela J, Fewer DP, Aitio O, Permi P, Wahlsten M, Wang H, Rouhiainen L, Sivonen K.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1909-17. doi: 10.1073/pnas.1320913111. Epub 2014 Apr 17.

32.

A novel structural unit in the N-terminal region of filamins.

Sethi R, Seppälä J, Tossavainen H, Ylilauri M, Ruskamo S, Pentikäinen OT, Pentikäinen U, Permi P, Ylänne J.

J Biol Chem. 2014 Mar 21;289(12):8588-98. doi: 10.1074/jbc.M113.537456. Epub 2014 Jan 27.

33.

H(N), N(H), C (α), C (β), and methyl group assignments of filamin multidomain fragments IgFLNc4-5 and IgFLNa3-5.

Tossavainen H, Seppälä J, Sethi R, Pihlajamaa T, Permi P.

Biomol NMR Assign. 2015 Apr;9(1):47-50. doi: 10.1007/s12104-014-9542-6. Epub 2014 Jan 11.

PMID:
24414222
34.

Bridge over troubled proline: assignment of intrinsically disordered proteins using (HCA)CON(CAN)H and (HCA)N(CA)CO(N)H experiments concomitantly with HNCO and i(HCA)CO(CA)NH.

Hellman M, Piirainen H, Jaakola VP, Permi P.

J Biomol NMR. 2014 Jan;58(1):49-60. doi: 10.1007/s10858-013-9804-0. Epub 2013 Dec 18.

PMID:
24346685
35.

New structural variants of aeruginosin produced by the toxic bloom forming cyanobacterium Nodularia spumigena.

Fewer DP, Jokela J, Paukku E, Österholm J, Wahlsten M, Permi P, Aitio O, Rouhiainen L, Gomez-Saez GV, Sivonen K.

PLoS One. 2013 Sep 6;8(9):e73618. doi: 10.1371/journal.pone.0073618. eCollection 2013.

36.

Genome mining expands the chemical diversity of the cyanobactin family to include highly modified linear peptides.

Leikoski N, Liu L, Jokela J, Wahlsten M, Gugger M, Calteau A, Permi P, Kerfeld CA, Sivonen K, Fewer DP.

Chem Biol. 2013 Aug 22;20(8):1033-43. doi: 10.1016/j.chembiol.2013.06.015. Epub 2013 Aug 1.

37.

Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues.

Pihlajamaa T, Kajander T, Knuuti J, Horkka K, Sharma A, Permi P.

Biochem J. 2013 Mar 15;450(3):469-76. doi: 10.1042/BJ20121058.

PMID:
23317521
38.

Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.

Aitio O, Hellman M, Skehan B, Kesti T, Leong JM, Saksela K, Permi P.

Structure. 2012 Oct 10;20(10):1692-703. doi: 10.1016/j.str.2012.07.015. Epub 2012 Aug 23.

39.

Anabaenolysins, novel cytolytic lipopeptides from benthic Anabaena cyanobacteria.

Jokela J, Oftedal L, Herfindal L, Permi P, Wahlsten M, Døskeland SO, Sivonen K.

PLoS One. 2012;7(7):e41222. doi: 10.1371/journal.pone.0041222. Epub 2012 Jul 19.

40.

Alpha proton detection based backbone assignment of intrinsically disordered proteins.

Permi P, Hellman M.

Methods Mol Biol. 2012;895:211-26. doi: 10.1007/978-1-61779-927-3_15.

PMID:
22760322
41.

SH3 domain ligand binding: What's the consensus and where's the specificity?

Saksela K, Permi P.

FEBS Lett. 2012 Aug 14;586(17):2609-14. doi: 10.1016/j.febslet.2012.04.042. Epub 2012 May 2. Review.

42.

Model of a six immunoglobulin-like domain fragment of filamin A (16-21) built using residual dipolar couplings.

Tossavainen H, Koskela O, Jiang P, Ylänne J, Campbell ID, Kilpeläinen I, Permi P.

J Am Chem Soc. 2012 Apr 18;134(15):6660-72. doi: 10.1021/ja2114882. Epub 2012 Apr 10.

PMID:
22452512
43.

Diversity in prokaryotic glycosylation: an archaeal-derived N-linked glycan contains legionaminic acid.

Kandiba L, Aitio O, Helin J, Guan Z, Permi P, Bamford DH, Eichler J, Roine E.

Mol Microbiol. 2012 May;84(3):578-93. doi: 10.1111/j.1365-2958.2012.08045.x. Epub 2012 Apr 11.

44.

Resonance assignments of the 56 kDa chimeric avidin in the biotin-bound and free forms.

Tossavainen H, Helppolainen SH, Määttä JA, Pihlajamaa T, Hytönen VP, Kulomaa MS, Permi P.

Biomol NMR Assign. 2013 Apr;7(1):35-8. doi: 10.1007/s12104-012-9371-4. Epub 2012 Mar 6.

PMID:
22392339
45.

Loosening of globular structure under alkaline pH affects accessibility of β-lactoglobulin to tyrosinase-induced oxidation and subsequent cross-linking.

Partanen R, Torkkeli M, Hellman M, Permi P, Serimaa R, Buchert J, Mattinen ML.

Enzyme Microb Technol. 2011 Jul 10;49(2):131-8. doi: 10.1016/j.enzmictec.2011.04.010. Epub 2011 Apr 21.

PMID:
22112399
46.

Characterization of intrinsically disordered prostate associated gene (PAGE5) at single residue resolution by NMR spectroscopy.

Hellman M, Tossavainen H, Rappu P, Heino J, Permi P.

PLoS One. 2011;6(11):e26633. doi: 10.1371/journal.pone.0026633. Epub 2011 Nov 2.

47.

Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins.

Mäntylahti S, Hellman M, Permi P.

J Biomol NMR. 2011 Feb;49(2):99-109. doi: 10.1007/s10858-011-9470-z. Epub 2011 Jan 25.

PMID:
21259120
48.

Protein analysis by 31p NMR spectroscopy in ionic liquid: quantitative determination of enzymatically created cross-links.

Monogioudi E, Permi P, Filpponen I, Lienemann M, Li B, Argyropoulos D, Buchert J, Mattinen ML.

J Agric Food Chem. 2011 Feb 23;59(4):1352-62. doi: 10.1021/jf102973d. Epub 2011 Jan 10.

PMID:
21218836
49.

Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly.

Aitio O, Hellman M, Kazlauskas A, Vingadassalom DF, Leong JM, Saksela K, Permi P.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21743-8. doi: 10.1073/pnas.1010243107. Epub 2010 Nov 22.

50.

Effect of protein structural integrity on cross-linking by tyrosinase evidenced by multidimensional heteronuclear magnetic resonance spectroscopy.

Hellman M, Mattinen ML, Fu B, Buchert J, Permi P.

J Biotechnol. 2011 Jan 10;151(1):143-50. doi: 10.1016/j.jbiotec.2010.11.006. Epub 2010 Nov 16.

PMID:
21087642

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